SK283970B6 - Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci - Google Patents

Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci Download PDF

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Publication number
SK283970B6
SK283970B6 SK1150-98A SK115098A SK283970B6 SK 283970 B6 SK283970 B6 SK 283970B6 SK 115098 A SK115098 A SK 115098A SK 283970 B6 SK283970 B6 SK 283970B6
Authority
SK
Slovakia
Prior art keywords
group
alkyl
carbon atoms
compound
aryl
Prior art date
Application number
SK1150-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK115098A3 (en
Inventor
Shigenori Ohkawa
Osamu Uchikawa
Kohji Fukatsu
Masaomi Miyamoto
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Publication of SK115098A3 publication Critical patent/SK115098A3/sk
Publication of SK283970B6 publication Critical patent/SK283970B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
SK1150-98A 1996-03-08 1997-03-05 Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci SK283970B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5149196 1996-03-08
JP18366796 1996-07-12
JP2918597 1997-02-13
PCT/JP1997/000677 WO1997032871A1 (en) 1996-03-08 1997-03-05 Tricyclic compounds, their production and use

Publications (2)

Publication Number Publication Date
SK115098A3 SK115098A3 (en) 1999-03-12
SK283970B6 true SK283970B6 (sk) 2004-06-08

Family

ID=27286462

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1150-98A SK283970B6 (sk) 1996-03-08 1997-03-05 Tricyklické zlúčeniny, spôsob výroby a farmaceutický prípravok ich obsahujúci

Country Status (20)

Country Link
US (1) US6218429B1 (no)
EP (2) EP1550655A1 (no)
JP (1) JP4358917B2 (no)
KR (1) KR100494214B1 (no)
CN (3) CN1900067A (no)
AT (1) ATE219071T1 (no)
CA (1) CA2241666C (no)
CZ (1) CZ291626B6 (no)
DE (1) DE69713294T3 (no)
DK (1) DK0885210T5 (no)
ES (1) ES2175350T5 (no)
HK (1) HK1087112A1 (no)
HU (1) HU224220B1 (no)
NO (1) NO322205B1 (no)
NZ (1) NZ330656A (no)
PL (1) PL188093B1 (no)
PT (1) PT885210E (no)
SK (1) SK283970B6 (no)
TW (1) TW562803B (no)
WO (1) WO1997032871A1 (no)

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AU6595000A (en) 1999-08-20 2001-03-19 Takeda Chemical Industries Ltd. Dihydrobenzofuran derivatives, process for the preparation thereof and agents
ATE443526T1 (de) * 1999-08-20 2009-10-15 Takeda Pharmaceutical Zusammensetzung für perkutane absorption mit einem melantoninrezeptor-agonistisch wirkendem wirkstoff
JP4632499B2 (ja) * 1999-08-26 2011-02-16 武田薬品工業株式会社 鼻粘膜付着マトリックス
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JP5588177B2 (ja) * 2008-01-31 2014-09-10 武田薬品工業株式会社 注意欠陥・多動性障害の予防または治療剤
US8871807B2 (en) 2008-03-28 2014-10-28 Ecolab Usa Inc. Detergents capable of cleaning, bleaching, sanitizing and/or disinfecting textiles including sulfoperoxycarboxylic acids
US8809392B2 (en) 2008-03-28 2014-08-19 Ecolab Usa Inc. Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents
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CN102321056B (zh) * 2011-07-29 2014-05-14 宁波人健药业集团股份有限公司 一种合成雷美替胺的方法
CN102391220A (zh) * 2011-10-10 2012-03-28 四川大学 三环乙醇类化合物及其制备方法和用途
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CN102924410A (zh) * 2012-10-29 2013-02-13 华润赛科药业有限责任公司 一种雷美替胺的制备方法及其中间体
US20140256811A1 (en) 2013-03-05 2014-09-11 Ecolab Usa Inc. Efficient stabilizer in controlling self accelerated decomposition temperature of peroxycarboxylic acid compositions with mineral acids
US10165774B2 (en) 2013-03-05 2019-01-01 Ecolab Usa Inc. Defoamer useful in a peracid composition with anionic surfactants
US8822719B1 (en) 2013-03-05 2014-09-02 Ecolab Usa Inc. Peroxycarboxylic acid compositions suitable for inline optical or conductivity monitoring
MX2016009180A (es) 2014-01-14 2016-10-05 Astellas Pharma Inc Compuesto de indol.
AU2017205519B2 (en) 2016-01-08 2022-01-27 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for delirium
US10759768B2 (en) 2016-01-08 2020-09-01 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for autism spectrum disorder
CN110776485B (zh) * 2019-11-22 2022-09-30 山东邹平大展新材料有限公司 一种雷美替胺杂质的制备方法
WO2023059546A1 (en) * 2021-10-04 2023-04-13 Psilosterics, Llc Serotonin receptor agonists and methods of making and using the same

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Also Published As

Publication number Publication date
US6218429B1 (en) 2001-04-17
DE69713294T3 (de) 2009-01-15
AU706610B2 (en) 1999-06-17
EP0885210B2 (en) 2008-06-18
DK0885210T3 (da) 2002-10-07
HU224220B1 (hu) 2005-06-28
WO1997032871A1 (en) 1997-09-12
CA2241666C (en) 2007-11-06
CN1727339A (zh) 2006-02-01
NO983970D0 (no) 1998-08-28
CN1212691A (zh) 1999-03-31
NZ330656A (en) 1999-06-29
CN1900067A (zh) 2007-01-24
DK0885210T4 (da) 2008-09-08
JPH11152281A (ja) 1999-06-08
PT885210E (pt) 2002-09-30
NO322205B1 (no) 2006-08-28
HK1087112A1 (en) 2006-10-06
KR100494214B1 (ko) 2005-11-25
CN100441574C (zh) 2008-12-10
DE69713294D1 (de) 2002-07-18
NO983970L (no) 1998-08-28
EP1550655A1 (en) 2005-07-06
PL328726A1 (en) 1999-02-15
EP0885210A1 (en) 1998-12-23
EP0885210B1 (en) 2002-06-12
DE69713294T2 (de) 2003-02-13
TW562803B (en) 2003-11-21
HUP9900616A2 (hu) 1999-06-28
KR19990087628A (ko) 1999-12-27
ATE219071T1 (de) 2002-06-15
HUP9900616A3 (en) 2002-11-28
SK115098A3 (en) 1999-03-12
AU2231897A (en) 1997-09-22
JP4358917B2 (ja) 2009-11-04
ES2175350T5 (es) 2008-12-16
DK0885210T5 (da) 2008-10-13
CZ277598A3 (cs) 1998-12-16
CA2241666A1 (en) 1997-09-12
PL188093B1 (pl) 2004-12-31
ES2175350T3 (es) 2002-11-16
CN100443480C (zh) 2008-12-17
CZ291626B6 (cs) 2003-04-16

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