ATE443526T1 - Zusammensetzung für perkutane absorption mit einem melantoninrezeptor-agonistisch wirkendem wirkstoff - Google Patents
Zusammensetzung für perkutane absorption mit einem melantoninrezeptor-agonistisch wirkendem wirkstoffInfo
- Publication number
- ATE443526T1 ATE443526T1 AT00953481T AT00953481T ATE443526T1 AT E443526 T1 ATE443526 T1 AT E443526T1 AT 00953481 T AT00953481 T AT 00953481T AT 00953481 T AT00953481 T AT 00953481T AT E443526 T1 ATE443526 T1 AT E443526T1
- Authority
- AT
- Austria
- Prior art keywords
- melantonin
- percutane
- composition
- active ingredient
- receptor agonistic
- Prior art date
Links
- 238000010521 absorption reaction Methods 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 230000001270 agonistic effect Effects 0.000 title 1
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 1
- 229940121723 Melatonin receptor agonist Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 1
- 229960003987 melatonin Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23410699 | 1999-08-20 | ||
| PCT/JP2000/005525 WO2001013950A1 (en) | 1999-08-20 | 2000-08-18 | Percutaneous absorption agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443526T1 true ATE443526T1 (de) | 2009-10-15 |
Family
ID=16965732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00953481T ATE443526T1 (de) | 1999-08-20 | 2000-08-18 | Zusammensetzung für perkutane absorption mit einem melantoninrezeptor-agonistisch wirkendem wirkstoff |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20090264521A1 (de) |
| EP (1) | EP1214944B1 (de) |
| AT (1) | ATE443526T1 (de) |
| AU (1) | AU6595100A (de) |
| CA (1) | CA2381468C (de) |
| DE (1) | DE60043017D1 (de) |
| WO (1) | WO2001013950A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002016337A1 (en) * | 2000-08-18 | 2002-02-28 | Takeda Chemical Industries, Ltd. | Tricyclic compounds and pharmaceutical compositions containing the same |
| DE10154324A1 (de) * | 2001-11-06 | 2003-08-07 | Merz Pharma Gmbh & Co Kgaa | Topisch applizierbare Zusammensetzungen mit externer Wirkstoffdepotbildung, deren Herstellung sowie deren Verwendung |
| EP1696959A2 (de) * | 2003-12-24 | 2006-09-06 | Sepracor, Inc. | Melatonin-kombinationstherapie zur verbesserung der schlafqualität |
| US20060223877A1 (en) * | 2005-03-31 | 2006-10-05 | Zemlan Frank P | Methods of treatment utilizing certain melatonin derivatives |
| AU2006282896A1 (en) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| AR061478A1 (es) | 2006-06-19 | 2008-08-27 | Takeda Pharmaceutical | Compuesto triciclico y composicion farmaceutica |
| JP2011529477A (ja) | 2008-07-30 | 2011-12-08 | フエルレル インターナショナル，ソシエダッド アノニマ | １，６−ジヒドロ−２ｈ−３−オキサ−６−アザ−ａｓ−インダセン化合物 |
| WO2010109913A1 (ja) * | 2009-03-27 | 2010-09-30 | トーアエイヨー株式会社 | 経皮吸収製剤 |
| JP5636715B2 (ja) * | 2009-03-27 | 2014-12-10 | トーアエイヨー株式会社 | 経皮吸収製剤 |
| JP5664991B2 (ja) * | 2009-03-27 | 2015-02-04 | トーアエイヨー株式会社 | 経皮吸収製剤 |
| BR112017013255B1 (pt) * | 2014-12-22 | 2022-08-09 | Hisamitsu Pharmaceutical Co., Inc | Cataplasma |
| US10744122B2 (en) * | 2015-02-04 | 2020-08-18 | Soeur Josefa Menendez | Transdermal therapeutic system containing valentonin and use thereof as a medicament |
| MX2022004257A (es) | 2019-10-11 | 2022-05-26 | Pike Therapeutics Inc | Composicion farmaceutica y metodo para tratamiento de los trastornos convulsionales. |
| CN117959197B (zh) * | 2023-12-28 | 2025-12-19 | 上海家化联合股份有限公司 | 基于聚甘油-10肉豆蔻酸酯的渗透组合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750134A (en) | 1989-11-03 | 1998-05-12 | Riker Laboratories, Inc. | Bioadhesive composition and patch |
| IT1254995B (it) | 1992-06-24 | 1995-10-11 | Farmaco contenente melatonina e/o agonisti, con somministrazione particolarmente efficace nelle patologie che interferiscono con i ritmi circandiani | |
| US6271015B1 (en) * | 1995-06-12 | 2001-08-07 | The Scripps Research Institute | Fatty-acid amide hydrolase |
| JPH09160821A (ja) * | 1995-12-01 | 1997-06-20 | Matsushita Electric Ind Co Ltd | ハイパーテキスト文書作成装置 |
| CN1210463A (zh) * | 1996-02-07 | 1999-03-10 | 株式会社津村 | 透明双氯芬酸钠的水溶液以及它的药物组合物 |
| JP2884153B2 (ja) | 1996-03-08 | 1999-04-19 | 武田薬品工業株式会社 | 三環性化合物、その製造法および剤 |
| US6034239A (en) * | 1996-03-08 | 2000-03-07 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| EP0885210B2 (de) | 1996-03-08 | 2008-06-18 | Takeda Pharmaceutical Company Limited | Tricyclische Verbindungen mit Bindungsaffinität für Melatoninrezeptoren, deren Herstellung und Verwendung |
| US5736154A (en) | 1996-03-11 | 1998-04-07 | Fuisz Technologies Ltd. | Transdermal delivery system |
| JPH1029934A (ja) | 1996-07-17 | 1998-02-03 | Teisan Seiyaku Kk | メラトニンを含有する貼付剤 |
| JPH1029933A (ja) | 1996-07-17 | 1998-02-03 | Teisan Seiyaku Kk | メラトニン含有貼付剤 |
| AU4990797A (en) | 1996-10-24 | 1998-05-15 | Alza Corporation | Permeation enhancers for transdermal drug delivery compositions, devices, and methods |
| JPH10182455A (ja) | 1996-12-24 | 1998-07-07 | Teisan Seiyaku Kk | メラトニン含有貼付剤 |
| JP4275751B2 (ja) * | 1996-12-27 | 2009-06-10 | 久光製薬株式会社 | 外用組成物 |
-
2000
- 2000-08-18 CA CA2381468A patent/CA2381468C/en not_active Expired - Fee Related
- 2000-08-18 EP EP00953481A patent/EP1214944B1/de not_active Expired - Lifetime
- 2000-08-18 AT AT00953481T patent/ATE443526T1/de not_active IP Right Cessation
- 2000-08-18 DE DE60043017T patent/DE60043017D1/de not_active Expired - Lifetime
- 2000-08-18 AU AU65951/00A patent/AU6595100A/en not_active Abandoned
- 2000-08-18 WO PCT/JP2000/005525 patent/WO2001013950A1/ja not_active Ceased
-
2009
- 2009-06-22 US US12/457,772 patent/US20090264521A1/en not_active Abandoned
-
2012
- 2012-08-15 US US13/586,273 patent/US20120309823A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6595100A (en) | 2001-03-19 |
| CA2381468C (en) | 2013-05-28 |
| CA2381468A1 (en) | 2001-03-01 |
| EP1214944A1 (de) | 2002-06-19 |
| EP1214944A4 (de) | 2005-03-16 |
| US20120309823A1 (en) | 2012-12-06 |
| WO2001013950A1 (en) | 2001-03-01 |
| US20090264521A1 (en) | 2009-10-22 |
| EP1214944B1 (de) | 2009-09-23 |
| DE60043017D1 (de) | 2009-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |