SK283958B6 - Forma B sodnej soli omeprazolu, spôsob jej prípravy, farmaceutický prípravok s jej obsahom a jej použitie - Google Patents

Forma B sodnej soli omeprazolu, spôsob jej prípravy, farmaceutický prípravok s jej obsahom a jej použitie Download PDF

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Publication number
SK283958B6
SK283958B6 SK1729-99A SK172999A SK283958B6 SK 283958 B6 SK283958 B6 SK 283958B6 SK 172999 A SK172999 A SK 172999A SK 283958 B6 SK283958 B6 SK 283958B6
Authority
SK
Slovakia
Prior art keywords
omeprazole sodium
omeprazole
sodium form
preparation
sodium salt
Prior art date
Application number
SK1729-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK172999A3 (en
Inventor
Anders Gustavsson
Kristina Kjellbom
Ingvar Ym�N
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of SK172999A3 publication Critical patent/SK172999A3/sk
Publication of SK283958B6 publication Critical patent/SK283958B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1729-99A 1997-06-27 1998-06-11 Forma B sodnej soli omeprazolu, spôsob jej prípravy, farmaceutický prípravok s jej obsahom a jej použitie SK283958B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9702483A SE510643C2 (sv) 1997-06-27 1997-06-27 Termodynamiskt stabil omeprazol natrium form B
PCT/SE1998/001124 WO1999000380A1 (en) 1997-06-27 1998-06-11 Omeprazole sodium salt

Publications (2)

Publication Number Publication Date
SK172999A3 SK172999A3 (en) 2000-07-11
SK283958B6 true SK283958B6 (sk) 2004-06-08

Family

ID=20407555

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1729-99A SK283958B6 (sk) 1997-06-27 1998-06-11 Forma B sodnej soli omeprazolu, spôsob jej prípravy, farmaceutický prípravok s jej obsahom a jej použitie

Country Status (35)

Country Link
US (1) US6207188B1 (xx)
EP (2) EP1186602A3 (xx)
JP (1) JP3377218B2 (xx)
KR (1) KR100580987B1 (xx)
CN (1) CN1134432C (xx)
AR (1) AR013350A1 (xx)
AT (1) ATE233756T1 (xx)
AU (1) AU750239B2 (xx)
BR (1) BR9810483A (xx)
CA (1) CA2294614C (xx)
CZ (1) CZ296723B6 (xx)
DE (1) DE69811892T2 (xx)
DK (1) DK0991641T3 (xx)
EE (1) EE03613B1 (xx)
EG (1) EG24224A (xx)
ES (1) ES2191944T3 (xx)
HK (1) HK1026699A1 (xx)
HU (1) HU227976B1 (xx)
ID (1) ID24829A (xx)
IL (2) IL133559A0 (xx)
IS (1) IS1946B (xx)
MY (1) MY127871A (xx)
NO (1) NO318245B1 (xx)
NZ (1) NZ501929A (xx)
PL (1) PL190869B1 (xx)
PT (1) PT991641E (xx)
RU (1) RU2186778C2 (xx)
SA (1) SA98190410B1 (xx)
SE (1) SE510643C2 (xx)
SK (1) SK283958B6 (xx)
TR (1) TR199903270T2 (xx)
TW (1) TW483758B (xx)
UA (1) UA58556C2 (xx)
WO (1) WO1999000380A1 (xx)
ZA (1) ZA985317B (xx)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
GB2324093A (en) 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
IL145220A0 (en) * 1999-05-20 2002-06-30 Par Pharmaceutical Inc Stabilized composition based on pyridinyl-sulfinyl-benzimidazoles and process
SE9903831D0 (sv) 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
EP1706397A4 (en) * 2000-05-15 2007-08-01 Ranbaxy Lab Ltd AMORPHOUS FORM OF OMEPRAZOLE SALTS
DE60123800T2 (de) * 2000-08-04 2007-10-11 Takeda Pharmaceutical Co. Ltd. Salze von benzimidazol-derivaten und deren verwendung
EP1310252A4 (en) 2000-08-18 2009-06-10 Takeda Pharmaceutical INJECTIONS
EP1411900B2 (en) * 2001-06-01 2013-12-04 Pozen, Inc. PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
AU2003278406A1 (en) * 2002-10-22 2004-05-13 Ranbaxy Laboratories Limited Amorphous form of esomeprazole salts
CN1842525A (zh) 2003-05-05 2006-10-04 兰贝克赛实验室有限公司 苯并咪唑衍生物的钡盐
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
CA2570795C (en) * 2004-06-24 2013-05-28 Astrazeneca Ab Process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
WO2006073779A1 (en) * 2004-12-30 2006-07-13 Transform Phamaceuticals, Inc. Novel omeprazole forms and related methods
US8247566B2 (en) * 2005-06-08 2012-08-21 Lek Pharmaceuticals D.D. Crystalline solvate of omeprazole sodium
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
CN101412710B (zh) * 2008-12-16 2010-04-21 海南百那医药发展有限公司 一种奥美拉唑钠化合物及其制法
EP2445499A4 (en) 2009-06-25 2013-02-27 Astrazeneca Ab METHOD FOR TREATING A PATIENT WITH RISK OF DEVELOPING A NSAID-ASSOCIATED SPURGE
CN102638978A (zh) * 2009-06-25 2012-08-15 波曾公司 用于治疗需要阿司匹林治疗之患者的方法
CN102351846B (zh) * 2011-09-07 2012-08-22 周晓东 一种新的奥美拉唑钠化合物及其药物组合物
CN102319223B (zh) * 2011-09-21 2013-06-19 石药集团欧意药业有限公司 一种埃索美拉唑冻干制剂及其制备方法
CN102512380B (zh) * 2011-12-20 2013-04-17 海南锦瑞制药股份有限公司 一种以奥美拉唑钠为活性成分的冻干粉针剂及其制备方法
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту
CN102827147B (zh) * 2012-09-13 2013-08-07 山东罗欣药业股份有限公司 一种奥美拉唑钠晶体化合物及含有该晶体化合物的药物组合物
CN102871973A (zh) * 2012-10-16 2013-01-16 浙江亚太药业股份有限公司 一种奥美拉唑钠冻干制剂及其制备方法
CN103012371B (zh) * 2013-01-05 2014-02-12 宁辉 奥美拉唑钠结晶化合物、其制备方法及其药物组合物
CN103570687B (zh) * 2013-11-15 2015-01-07 悦康药业集团有限公司 一种奥美拉唑钠晶体化合物
CN104788426B (zh) * 2015-04-02 2015-12-30 天津大学 一种奥美拉唑钠半水合物及其制备方法
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification
CN116041325A (zh) * 2022-12-09 2023-05-02 山东北大高科华泰制药有限公司 稳定化质子泵抑制剂的方法

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DE2719916C2 (de) * 1977-05-04 1987-03-19 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decanen
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
ES2023778A6 (es) * 1990-12-12 1992-02-01 Genesis Para La Investigacion Procedimiento para preparar sales alcalinas del omeprazol
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
CZ289804B6 (cs) 1994-07-08 2002-04-17 Astrazeneca Ab Multijednotková tabletovaná dávková forma I
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
CN1042423C (zh) * 1995-05-25 1999-03-10 常州市第四制药厂 奥美拉唑盐水合物及其制备方法
AU5982298A (en) * 1997-03-07 1998-09-29 A/S Gea Farmaceutisk Fabrik Process for the preparation of 2-{{(2-pyridinyl)me thyl}sulfinyl}-1h-benzimidazoles and novel compounds of use for such purpos
EP0968204A1 (en) * 1997-03-07 2000-01-05 A/S GEA Farmaceutisk Fabrik Process for the preparation of 2- (2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose
SE510643C2 (sv) 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B

Also Published As

Publication number Publication date
DK0991641T3 (da) 2003-05-19
EE03613B1 (et) 2002-02-15
CA2294614A1 (en) 1999-01-07
EP0991641A1 (en) 2000-04-12
EE9900593A (et) 2000-08-15
IL133559A0 (en) 2001-04-30
PL337735A1 (en) 2000-08-28
NZ501929A (en) 2001-06-29
CZ469999A3 (cs) 2000-08-16
EP1186602A2 (en) 2002-03-13
NO318245B1 (no) 2005-02-21
ZA985317B (en) 1999-01-11
UA58556C2 (uk) 2003-08-15
SE510643C2 (sv) 1999-06-14
ES2191944T3 (es) 2003-09-16
IS1946B (is) 2004-10-13
HUP0003017A3 (en) 2002-01-28
CN1261362A (zh) 2000-07-26
DE69811892T2 (de) 2004-03-04
SK172999A3 (en) 2000-07-11
BR9810483A (pt) 2000-09-12
IL133559A (en) 2006-04-10
SE9702483L (sv) 1998-12-28
KR100580987B1 (ko) 2006-05-17
EP1186602A3 (en) 2002-03-27
ID24829A (id) 2000-08-24
NO996440D0 (no) 1999-12-23
SE9702483D0 (sv) 1997-06-27
EP0991641B1 (en) 2003-03-05
CA2294614C (en) 2002-01-08
AU8135398A (en) 1999-01-19
CN1134432C (zh) 2004-01-14
PT991641E (pt) 2003-06-30
DE69811892D1 (de) 2003-04-10
WO1999000380A1 (en) 1999-01-07
PL190869B1 (pl) 2006-02-28
AU750239B2 (en) 2002-07-11
RU2186778C2 (ru) 2002-08-10
IS5314A (is) 1999-12-21
JP2001508805A (ja) 2001-07-03
US6207188B1 (en) 2001-03-27
KR20010014165A (ko) 2001-02-26
MY127871A (en) 2006-12-29
TW483758B (en) 2002-04-21
NO996440L (no) 2000-02-08
EG24224A (en) 2008-11-10
HU227976B1 (en) 2012-07-30
SA98190410B1 (ar) 2006-06-10
JP3377218B2 (ja) 2003-02-17
ATE233756T1 (de) 2003-03-15
HK1026699A1 (en) 2000-12-22
AR013350A1 (es) 2000-12-27
CZ296723B6 (cs) 2006-05-17
TR199903270T2 (xx) 2000-07-21
HUP0003017A2 (hu) 2001-06-28

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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20160611