SK282949B6 - Stabilný vodný prostriedok, stabilný vodný roztok, výrobok, spôsob prípravy stabilného vodného prostriedku a sterilizovaná plniaca nádoba - Google Patents

Stabilný vodný prostriedok, stabilný vodný roztok, výrobok, spôsob prípravy stabilného vodného prostriedku a sterilizovaná plniaca nádoba Download PDF

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Publication number
SK282949B6
SK282949B6 SK439-97A SK43997A SK282949B6 SK 282949 B6 SK282949 B6 SK 282949B6 SK 43997 A SK43997 A SK 43997A SK 282949 B6 SK282949 B6 SK 282949B6
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SK
Slovakia
Prior art keywords
alpha
interferon
polysorbate
water
composition
Prior art date
Application number
SK439-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK43997A3 (en
Inventor
Pui-Ho C. Yuen
Douglas F. Kline
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of SK43997A3 publication Critical patent/SK43997A3/sk
Publication of SK282949B6 publication Critical patent/SK282949B6/sk

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
SK439-97A 1994-10-11 1995-10-10 Stabilný vodný prostriedok, stabilný vodný roztok, výrobok, spôsob prípravy stabilného vodného prostriedku a sterilizovaná plniaca nádoba SK282949B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/329,813 US5766582A (en) 1994-10-11 1994-10-11 Stable, aqueous alfa interferon solution formulations
PCT/US1995/012362 WO1996011018A1 (en) 1994-10-11 1995-10-10 Stable, aqueous alfa interferon solution formulations

Publications (2)

Publication Number Publication Date
SK43997A3 SK43997A3 (en) 1997-10-08
SK282949B6 true SK282949B6 (sk) 2003-01-09

Family

ID=23287133

Family Applications (1)

Application Number Title Priority Date Filing Date
SK439-97A SK282949B6 (sk) 1994-10-11 1995-10-10 Stabilný vodný prostriedok, stabilný vodný roztok, výrobok, spôsob prípravy stabilného vodného prostriedku a sterilizovaná plniaca nádoba

Country Status (25)

Country Link
US (2) US5766582A (hu)
EP (2) EP0777495B1 (hu)
JP (2) JP3978228B2 (hu)
KR (1) KR100401401B1 (hu)
CN (1) CN1102408C (hu)
AT (2) ATE245033T1 (hu)
AU (1) AU708337B2 (hu)
BR (1) BR9509313A (hu)
CA (1) CA2201749C (hu)
CZ (1) CZ296961B6 (hu)
DE (2) DE69518084T2 (hu)
DK (1) DK0777495T3 (hu)
ES (2) ES2148568T3 (hu)
FI (2) FI116558B (hu)
GR (1) GR3034619T3 (hu)
HK (1) HK1008813A1 (hu)
HU (1) HU225494B1 (hu)
NO (1) NO320604B1 (hu)
NZ (1) NZ294464A (hu)
PL (1) PL183797B1 (hu)
PT (1) PT777495E (hu)
RU (1) RU2157236C2 (hu)
SK (1) SK282949B6 (hu)
UA (1) UA42028C2 (hu)
WO (1) WO1996011018A1 (hu)

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JP5281726B2 (ja) 1998-05-15 2013-09-04 メルク・シャープ・アンド・ドーム・コーポレーション 慢性Ｃ型肝炎感染を有する、抗ウイルス処置を受けていない患者における、リバビリンおよびインターフェロンαを含む併用療法
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TW577894B (en) 1998-11-12 2004-03-01 Schering Corp Methods for conversion of protein isoforms and products thereof
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US6362162B1 (en) 1999-04-08 2002-03-26 Schering Corporation CML Therapy
ATE419001T1 (de) 1999-04-08 2009-01-15 Schering Corp Melanoma therapie
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Also Published As

Publication number Publication date
CA2201749A1 (en) 1996-04-18
DE69531314D1 (de) 2003-08-21
PL319603A1 (en) 1997-08-18
AU3727995A (en) 1996-05-02
ES2198830T3 (es) 2004-02-01
AU708337B2 (en) 1999-08-05
EP0970703A1 (en) 2000-01-12
HK1008813A1 (en) 1999-05-21
CN1160355A (zh) 1997-09-24
ATE245033T1 (de) 2003-08-15
FI971486A (fi) 1997-04-10
JP2006193536A (ja) 2006-07-27
WO1996011018A1 (en) 1996-04-18
NO320604B1 (no) 2005-12-27
CN1102408C (zh) 2003-03-05
US5935566A (en) 1999-08-10
ES2148568T3 (es) 2000-10-16
SK43997A3 (en) 1997-10-08
CZ110497A3 (en) 1997-09-17
FI117377B (fi) 2006-09-29
EP0777495B1 (en) 2000-07-19
MX9702578A (es) 1997-07-31
EP0777495A1 (en) 1997-06-11
JPH10506912A (ja) 1998-07-07
DE69518084D1 (de) 2000-08-24
PT777495E (pt) 2000-12-29
US5766582A (en) 1998-06-16
CA2201749C (en) 1999-06-15
NO971633L (no) 1997-04-10
FI20055562A (fi) 2005-10-19
EP0970703B1 (en) 2003-07-16
BR9509313A (pt) 1998-01-27
DE69531314T2 (de) 2004-05-13
FI116558B (fi) 2005-12-30
GR3034619T3 (en) 2001-01-31
HU225494B1 (en) 2007-01-29
UA42028C2 (uk) 2001-10-15
CZ296961B6 (cs) 2006-08-16
DK0777495T3 (da) 2000-11-06
KR100401401B1 (ko) 2004-02-18
KR970706017A (ko) 1997-11-03
FI971486A0 (fi) 1997-04-10
ATE194774T1 (de) 2000-08-15
DE69518084T2 (de) 2001-03-22
NZ294464A (en) 1999-03-29
NO971633D0 (no) 1997-04-10
HUT77287A (hu) 1998-03-30
JP3978228B2 (ja) 2007-09-19
PL183797B1 (pl) 2002-07-31
RU2157236C2 (ru) 2000-10-10

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Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121108

MK4A Patent expired

Expiry date: 20151010