SK17302001A3 - Tiazolové zlúčeniny a farmaceutické zmesi na inhibíciu proteínkináz a na metódy ich využívania - Google Patents

Tiazolové zlúčeniny a farmaceutické zmesi na inhibíciu proteínkináz a na metódy ich využívania Download PDF

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Publication number
SK17302001A3
SK17302001A3 SK1730-2001A SK17302001A SK17302001A3 SK 17302001 A3 SK17302001 A3 SK 17302001A3 SK 17302001 A SK17302001 A SK 17302001A SK 17302001 A3 SK17302001 A3 SK 17302001A3
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SK
Slovakia
Prior art keywords
amino
aryl
heteroaryl
substituted
pharmaceutically acceptable
Prior art date
Application number
SK1730-2001A
Other languages
English (en)
Slovak (sk)
Inventor
Shao Song Chu
Larry Andrew Alegria
Steven Lee Bender
Suzanne Pritchett Benedict
Allen J. Borchardt
Robert Steven Kania
Mitchell David Nambu
Anna Marie Tempczyk-Russell
Sepehr Sarshar
Dilip Bhumralkar
Zhengwei Peng
Yi Michelle Yang
Original Assignee
Agouron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharmaceuticals, Inc. filed Critical Agouron Pharmaceuticals, Inc.
Publication of SK17302001A3 publication Critical patent/SK17302001A3/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1730-2001A 1999-06-04 2000-06-02 Tiazolové zlúčeniny a farmaceutické zmesi na inhibíciu proteínkináz a na metódy ich využívania SK17302001A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13781099P 1999-06-04 1999-06-04
PCT/US2000/015188 WO2000075120A1 (en) 1999-06-04 2000-06-02 Diaminothiazoles and their use for inhibiting protein kinases

Publications (1)

Publication Number Publication Date
SK17302001A3 true SK17302001A3 (sk) 2004-01-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SK1730-2001A SK17302001A3 (sk) 1999-06-04 2000-06-02 Tiazolové zlúčeniny a farmaceutické zmesi na inhibíciu proteínkináz a na metódy ich využívania

Country Status (34)

Country Link
US (1) US6620828B2 (enExample)
EP (1) EP1181283B1 (enExample)
JP (1) JP2003501420A (enExample)
KR (1) KR20020015333A (enExample)
CN (1) CN1359380A (enExample)
AP (1) AP2001002341A0 (enExample)
AT (1) ATE288424T1 (enExample)
AU (1) AU778071B2 (enExample)
BG (1) BG106276A (enExample)
BR (1) BR0011585A (enExample)
CA (1) CA2371158A1 (enExample)
CZ (1) CZ20014213A3 (enExample)
DE (1) DE60017894T2 (enExample)
EA (1) EA200101268A1 (enExample)
EE (1) EE200100659A (enExample)
ES (1) ES2234628T3 (enExample)
HR (1) HRP20020008A2 (enExample)
HU (1) HUP0202897A3 (enExample)
IL (1) IL146094A0 (enExample)
IS (1) IS6183A (enExample)
MA (1) MA25530A1 (enExample)
MX (1) MXPA01012483A (enExample)
NO (1) NO20015045L (enExample)
NZ (1) NZ514881A (enExample)
OA (1) OA11959A (enExample)
PE (1) PE20010211A1 (enExample)
PL (1) PL352714A1 (enExample)
SK (1) SK17302001A3 (enExample)
SV (1) SV2002000096A (enExample)
UA (1) UA71971C2 (enExample)
UY (1) UY26190A1 (enExample)
WO (1) WO2000075120A1 (enExample)
YU (1) YU85601A (enExample)
ZA (1) ZA200108291B (enExample)

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MXPA01012483A (es) 2002-07-30
JP2003501420A (ja) 2003-01-14
CA2371158A1 (en) 2000-12-14
PL352714A1 (en) 2003-09-08
NO20015045L (no) 2002-02-04
EA200101268A1 (ru) 2002-06-27
HUP0202897A2 (hu) 2002-12-28
HUP0202897A3 (en) 2004-12-28
EE200100659A (et) 2003-02-17
ATE288424T1 (de) 2005-02-15
EP1181283A1 (en) 2002-02-27
IS6183A (is) 2001-11-29
MA25530A1 (fr) 2002-10-01
IL146094A0 (en) 2002-07-25
KR20020015333A (ko) 2002-02-27
BR0011585A (pt) 2002-03-19
UA71971C2 (en) 2005-01-17
YU85601A (sh) 2004-09-03
WO2000075120A1 (en) 2000-12-14
DE60017894T2 (de) 2005-12-29
ES2234628T3 (es) 2005-07-01
EP1181283B1 (en) 2005-02-02
US6620828B2 (en) 2003-09-16
BG106276A (bg) 2002-10-31
UY26190A1 (es) 2000-12-29
SV2002000096A (es) 2002-06-07
NZ514881A (en) 2003-10-31
AU5725400A (en) 2000-12-28
US20020025976A1 (en) 2002-02-28
NO20015045D0 (no) 2001-10-17
DE60017894D1 (de) 2005-03-10
AP2001002341A0 (en) 2001-12-31
AU778071B2 (en) 2004-11-11
PE20010211A1 (es) 2001-03-16
ZA200108291B (en) 2002-12-24
CZ20014213A3 (cs) 2002-04-17
HRP20020008A2 (en) 2004-02-29
CN1359380A (zh) 2002-07-17
OA11959A (en) 2006-04-17

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