SI3805233T1 - (r)in (s) enantiomera n-(5-(3-hidroksipirolidin-1-il)-2-morfolinooksazolo(4,5-b)piridin-6-il) -2-(2-metilpiridin-4-il)oksazol-karboksamid kot inhibitorji irak4 za zdravljenje raka - Google Patents

(r)in (s) enantiomera n-(5-(3-hidroksipirolidin-1-il)-2-morfolinooksazolo(4,5-b)piridin-6-il) -2-(2-metilpiridin-4-il)oksazol-karboksamid kot inhibitorji irak4 za zdravljenje raka

Info

Publication number
SI3805233T1
SI3805233T1 SI201532008T SI201532008T SI3805233T1 SI 3805233 T1 SI3805233 T1 SI 3805233T1 SI 201532008 T SI201532008 T SI 201532008T SI 201532008 T SI201532008 T SI 201532008T SI 3805233 T1 SI3805233 T1 SI 3805233T1
Authority
SI
Slovenia
Prior art keywords
morpholinooxazolo
hydroxypyrrolidin
methylpyridin
oxazole
enantiomer
Prior art date
Application number
SI201532008T
Other languages
English (en)
Slovenian (sl)
Inventor
Venkateshwar Rao Gummadi
Susanta Samajdar
Original Assignee
Aurigene Oncology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurigene Oncology Limited filed Critical Aurigene Oncology Limited
Publication of SI3805233T1 publication Critical patent/SI3805233T1/sl

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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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SI201532008T 2014-01-13 2015-01-12 (r)in (s) enantiomera n-(5-(3-hidroksipirolidin-1-il)-2-morfolinooksazolo(4,5-b)piridin-6-il) -2-(2-metilpiridin-4-il)oksazol-karboksamid kot inhibitorji irak4 za zdravljenje raka SI3805233T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN158CH2014 2014-01-13
IN3000CH2014 2014-06-20
EP20211096.1A EP3805233B1 (en) 2014-01-13 2015-01-12 (r) and (s) enantiomers of n-(5-(3-hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-carboxamide as irak4 inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
SI3805233T1 true SI3805233T1 (sl) 2024-07-31

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SI201530477T SI3094329T1 (sl) 2014-01-13 2015-01-12 Biciklični heterociklilni derivati kot inhibitorji IRAK4
SI201531483T SI3466955T1 (sl) 2014-01-13 2015-01-12 Postopek za pripravo derivatov oksazolo(4,5-B)piridina in tiazolo(4,5-B)piridina kot inhibitorjev IRAK4 za zdravljenje raka
SI201532008T SI3805233T1 (sl) 2014-01-13 2015-01-12 (r)in (s) enantiomera n-(5-(3-hidroksipirolidin-1-il)-2-morfolinooksazolo(4,5-b)piridin-6-il) -2-(2-metilpiridin-4-il)oksazol-karboksamid kot inhibitorji irak4 za zdravljenje raka

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SI201530477T SI3094329T1 (sl) 2014-01-13 2015-01-12 Biciklični heterociklilni derivati kot inhibitorji IRAK4
SI201531483T SI3466955T1 (sl) 2014-01-13 2015-01-12 Postopek za pripravo derivatov oksazolo(4,5-B)piridina in tiazolo(4,5-B)piridina kot inhibitorjev IRAK4 za zdravljenje raka

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US (8) US9732095B2 (cg-RX-API-DMAC7.html)
EP (4) EP3094329B1 (cg-RX-API-DMAC7.html)
JP (6) JP6479850B2 (cg-RX-API-DMAC7.html)
KR (4) KR102392684B1 (cg-RX-API-DMAC7.html)
CN (2) CN111362966B (cg-RX-API-DMAC7.html)
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JP6479850B2 (ja) 2019-03-06
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DK3466955T3 (da) 2021-02-01
HUE066261T2 (hu) 2024-07-28
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JP2017502088A (ja) 2017-01-19
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