RS61448B1 - Način pripreme derivata oksazolo [4,5-b] piridina i tiazolo [4,5-b] piridina kao irak4 inhibitora za lečenje raka - Google Patents
Način pripreme derivata oksazolo [4,5-b] piridina i tiazolo [4,5-b] piridina kao irak4 inhibitora za lečenje rakaInfo
- Publication number
- RS61448B1 RS61448B1 RS20210039A RSP20210039A RS61448B1 RS 61448 B1 RS61448 B1 RS 61448B1 RS 20210039 A RS20210039 A RS 20210039A RS P20210039 A RSP20210039 A RS P20210039A RS 61448 B1 RS61448 B1 RS 61448B1
- Authority
- RS
- Serbia
- Prior art keywords
- pyridine
- oxazolo
- thiazolo
- preparing
- treating cancer
- Prior art date
Links
- 229940127590 IRAK4 inhibitor Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- BBAWTPDTGRXPDG-UHFFFAOYSA-N [1,3]thiazolo[4,5-b]pyridine Chemical class C1=CC=C2SC=NC2=N1 BBAWTPDTGRXPDG-UHFFFAOYSA-N 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- QNNHQVPFZIFNFK-UHFFFAOYSA-N oxazolo[4,5-b]pyridine Chemical compound C1=CC=C2OC=NC2=N1 QNNHQVPFZIFNFK-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
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- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
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- Communicable Diseases (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN158CH2014 | 2014-01-13 | ||
IN3000CH2014 | 2014-06-20 | ||
EP18190333.7A EP3466955B1 (en) | 2014-01-13 | 2015-01-12 | Method of preparing oxazolo[4,5-b]pyridine and thiazolo[4,5-b]pyridine derivatives as irak4 inhibitors for treating cancer |
Publications (1)
Publication Number | Publication Date |
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RS61448B1 true RS61448B1 (sr) | 2021-03-31 |
Family
ID=53523587
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20240415A RS65437B1 (sr) | 2014-01-13 | 2015-01-12 | (r) i (s) enantiomeri n-(5-(3-hidroksipirolidin-1-il)-2-morfolinooksazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)oksazol-karboksamida kao inhibitori irak4 za lečenje kancera |
RS20181355A RS58024B1 (sr) | 2014-01-13 | 2015-01-12 | Biciklični heterociklični derivati kao irak4 inhibitori |
RS20210039A RS61448B1 (sr) | 2014-01-13 | 2015-01-12 | Način pripreme derivata oksazolo [4,5-b] piridina i tiazolo [4,5-b] piridina kao irak4 inhibitora za lečenje raka |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20240415A RS65437B1 (sr) | 2014-01-13 | 2015-01-12 | (r) i (s) enantiomeri n-(5-(3-hidroksipirolidin-1-il)-2-morfolinooksazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)oksazol-karboksamida kao inhibitori irak4 za lečenje kancera |
RS20181355A RS58024B1 (sr) | 2014-01-13 | 2015-01-12 | Biciklični heterociklični derivati kao irak4 inhibitori |
Country Status (31)
Country | Link |
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US (6) | US9732095B2 (sr) |
EP (4) | EP3805233B1 (sr) |
JP (5) | JP6479850B2 (sr) |
KR (3) | KR20230129622A (sr) |
CN (2) | CN106456619B (sr) |
AU (5) | AU2015205374B2 (sr) |
BR (1) | BR112016016158B1 (sr) |
CA (1) | CA2935887A1 (sr) |
CU (1) | CU24389B1 (sr) |
CY (2) | CY1121433T1 (sr) |
DK (3) | DK3466955T3 (sr) |
EA (2) | EA038748B1 (sr) |
ES (3) | ES2846678T3 (sr) |
FI (1) | FI3805233T3 (sr) |
HK (1) | HK1231410A1 (sr) |
HR (3) | HRP20240489T1 (sr) |
HU (3) | HUE052252T2 (sr) |
IL (6) | IL284952B (sr) |
LT (3) | LT3805233T (sr) |
MX (1) | MX359909B (sr) |
MY (1) | MY197116A (sr) |
NZ (2) | NZ760657A (sr) |
PH (2) | PH12016501344A1 (sr) |
PL (3) | PL3094329T3 (sr) |
PT (3) | PT3094329T (sr) |
RS (3) | RS65437B1 (sr) |
SG (2) | SG10201811204RA (sr) |
SI (3) | SI3466955T1 (sr) |
TR (1) | TR201815683T4 (sr) |
WO (1) | WO2015104688A1 (sr) |
ZA (2) | ZA202007273B (sr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201311888D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
GB201311891D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compound |
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