SMT202400142T1 - Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro - Google Patents

Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro

Info

Publication number
SMT202400142T1
SMT202400142T1 SM20240142T SMT202400142T SMT202400142T1 SM T202400142 T1 SMT202400142 T1 SM T202400142T1 SM 20240142 T SM20240142 T SM 20240142T SM T202400142 T SMT202400142 T SM T202400142T SM T202400142 T1 SMT202400142 T1 SM T202400142T1
Authority
SM
San Marino
Prior art keywords
morpholinooxazolo
hydroxypyrrolidin
methylpyridin
oxazole
carboxamide
Prior art date
Application number
SM20240142T
Other languages
English (en)
Italian (it)
Inventor
Venkateshwar Rao Gummadi
Susanta Samajdar
Original Assignee
Aurigene Oncology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurigene Oncology Ltd filed Critical Aurigene Oncology Ltd
Publication of SMT202400142T1 publication Critical patent/SMT202400142T1/it

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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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SM20240142T 2014-01-13 2015-01-12 Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro SMT202400142T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN158CH2014 2014-01-13
IN3000CH2014 2014-06-20
EP20211096.1A EP3805233B1 (en) 2014-01-13 2015-01-12 (r) and (s) enantiomers of n-(5-(3-hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-carboxamide as irak4 inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
SMT202400142T1 true SMT202400142T1 (it) 2024-05-14

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Family Applications (3)

Application Number Title Priority Date Filing Date
SM20240142T SMT202400142T1 (it) 2014-01-13 2015-01-12 Enantiomeri (r) e (s) di n-(5-(3-idrossipirrolidin-1-il)-2-morfolinoossazolo[4,5-b]piridin-6-il)-2-(2-metilpiridin-4-il)ossazolo-carbossammide in qualità di inibitori di irak4 per il trattamento di un cancro
SM20180680T SMT201800680T1 (it) 2014-01-13 2015-01-12 Derivati eterociclici e biciclici come inibitori di irak4
SM20210063T SMT202100063T1 (it) 2014-01-13 2015-01-12 Metodo di preparazione di derivati di ossazolo [4, 5-b] piridina e tiazolo [4, 5-b] piridina come inibitori di irak4 per il trattamento del cancro

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Application Number Title Priority Date Filing Date
SM20180680T SMT201800680T1 (it) 2014-01-13 2015-01-12 Derivati eterociclici e biciclici come inibitori di irak4
SM20210063T SMT202100063T1 (it) 2014-01-13 2015-01-12 Metodo di preparazione di derivati di ossazolo [4, 5-b] piridina e tiazolo [4, 5-b] piridina come inibitori di irak4 per il trattamento del cancro

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US (8) US9732095B2 (cg-RX-API-DMAC7.html)
EP (4) EP3094329B1 (cg-RX-API-DMAC7.html)
JP (6) JP6479850B2 (cg-RX-API-DMAC7.html)
KR (4) KR102392684B1 (cg-RX-API-DMAC7.html)
CN (2) CN111362966B (cg-RX-API-DMAC7.html)
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