US6361943B1
(en)
|
1996-10-17 |
2002-03-26 |
Mitsubishi Chemical Corporation |
Molecule that homologizes genotype and phenotype and utilization thereof
|
US3719667A
(en)
|
1970-08-24 |
1973-03-06 |
Lilly Co Eli |
Epimerization of 6-acylamido and 6-imido penicillin sulfoxide esters
|
US3840556A
(en)
|
1971-05-28 |
1974-10-08 |
Lilly Co Eli |
Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby
|
JPS60222842A
(ja)
|
1984-04-19 |
1985-11-07 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真乳剤およびその製造方法
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
US4965188A
(en)
|
1986-08-22 |
1990-10-23 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
|
US6040166A
(en)
*
|
1985-03-28 |
2000-03-21 |
Roche Molecular Systems, Inc. |
Kits for amplifying and detecting nucleic acid sequences, including a probe
|
US4822731A
(en)
|
1986-01-09 |
1989-04-18 |
Cetus Corporation |
Process for labeling single-stranded nucleic acids and hybridizaiton probes
|
US4800159A
(en)
|
1986-02-07 |
1989-01-24 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences
|
US5047519A
(en)
*
|
1986-07-02 |
1991-09-10 |
E. I. Du Pont De Nemours And Company |
Alkynylamino-nucleotides
|
EP0260032B1
(en)
|
1986-09-08 |
1994-01-26 |
Ajinomoto Co., Inc. |
Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers
|
US5449602A
(en)
|
1988-01-13 |
1995-09-12 |
Amoco Corporation |
Template-directed photoligation
|
US5025388A
(en)
|
1988-08-26 |
1991-06-18 |
Cramer Richard D Iii |
Comparative molecular field analysis (CoMFA)
|
EP0446299A4
(en)
|
1988-11-18 |
1992-05-13 |
The Regents Of The University Of California |
Method for site-specifically incorporating unnatural amino acids into proteins
|
US5324829A
(en)
*
|
1988-12-16 |
1994-06-28 |
Ortho Diagnostic Systems, Inc. |
High specific activity nucleic acid probes having target recognition and signal generating moieties
|
EP0494955B1
(en)
|
1989-10-05 |
1998-07-15 |
Optein, Inc. |
Cell-free synthesis and isolation of novel genes and polypeptides
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
US6005087A
(en)
|
1995-06-06 |
1999-12-21 |
Isis Pharmaceuticals, Inc. |
2'-modified oligonucleotides
|
CA2039517C
(en)
*
|
1990-04-03 |
2006-11-07 |
David Segev |
Dna probe signal amplification
|
US5660985A
(en)
|
1990-06-11 |
1997-08-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands containing modified nucleotides
|
US5723289A
(en)
|
1990-06-11 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
Parallel selex
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
US5650489A
(en)
|
1990-07-02 |
1997-07-22 |
The Arizona Board Of Regents |
Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
|
AU8498091A
(en)
|
1990-08-02 |
1992-03-02 |
Regents Of The University Of Colorado, The |
Systematic polypeptide evolution by reverse translation
|
US5843701A
(en)
*
|
1990-08-02 |
1998-12-01 |
Nexstar Pharmaceticals, Inc. |
Systematic polypeptide evolution by reverse translation
|
US5432272A
(en)
|
1990-10-09 |
1995-07-11 |
Benner; Steven A. |
Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
|
US6037120A
(en)
|
1995-10-12 |
2000-03-14 |
Benner; Steven Albert |
Recognition of oligonucleotides containing non-standard base pairs
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
AU2313392A
(en)
|
1991-08-01 |
1993-03-02 |
University Research Corporation |
Systematic polypeptide evolution by reverse translation
|
US5474796A
(en)
*
|
1991-09-04 |
1995-12-12 |
Protogene Laboratories, Inc. |
Method and apparatus for conducting an array of chemical reactions on a support surface
|
WO1993006121A1
(en)
|
1991-09-18 |
1993-04-01 |
Affymax Technologies N.V. |
Method of synthesizing diverse collections of oligomers
|
US5639603A
(en)
|
1991-09-18 |
1997-06-17 |
Affymax Technologies N.V. |
Synthesizing and screening molecular diversity
|
US6197556B1
(en)
*
|
1991-12-20 |
2001-03-06 |
The University Of Chicago |
Nucleic acid amplification using modular branched primers
|
US5424413A
(en)
*
|
1992-01-22 |
1995-06-13 |
Gen-Probe Incorporated |
Branched nucleic acid probes
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
US5541061A
(en)
|
1992-04-29 |
1996-07-30 |
Affymax Technologies N.V. |
Methods for screening factorial chemical libraries
|
HUT72495A
(en)
|
1992-10-01 |
1996-05-28 |
Cold Spring Harbor Lab |
Complex combinatorial chemical libraries encoded with tags
|
US5565324A
(en)
*
|
1992-10-01 |
1996-10-15 |
The Trustees Of Columbia University In The City Of New York |
Complex combinatorial chemical libraries encoded with tags
|
US6503759B1
(en)
*
|
1992-10-01 |
2003-01-07 |
The Trustees Of Columbia University In The City Of New York |
Complex combinatorial chemical libraries encoded with tags
|
US5684169A
(en)
*
|
1992-11-27 |
1997-11-04 |
Ensuiko Sugar Refining Co., Ltd. |
Cyclodextrin inclusion complex of taxol, and method for its production and its use
|
AU5827294A
(en)
|
1992-12-11 |
1994-07-04 |
Chiron Corporation |
Synthesis of encoded polymers
|
DE69433010T2
(de)
|
1993-04-12 |
2004-06-09 |
Northwestern University, Evanston |
Verfahren zur darstellung von oligonukleotiden
|
US5681943A
(en)
|
1993-04-12 |
1997-10-28 |
Northwestern University |
Method for covalently linking adjacent oligonucleotides
|
NZ267843A
(en)
*
|
1993-05-27 |
1997-10-24 |
Selectide Corp |
Libraries of synthetic test compound attached to separate phase synthesis supports
|
US5840485A
(en)
*
|
1993-05-27 |
1998-11-24 |
Selectide Corporation |
Topologically segregated, encoded solid phase libraries
|
WO1995001365A1
(en)
*
|
1993-07-02 |
1995-01-12 |
Lynx Therapeutics, Inc. |
Synthesis of branched nucleic acids
|
US5473060A
(en)
*
|
1993-07-02 |
1995-12-05 |
Lynx Therapeutics, Inc. |
Oligonucleotide clamps having diagnostic applications
|
US5571903A
(en)
|
1993-07-09 |
1996-11-05 |
Lynx Therapeutics, Inc. |
Auto-ligating oligonucleotide compounds
|
US6087186A
(en)
*
|
1993-07-16 |
2000-07-11 |
Irori |
Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
|
GB9315847D0
(en)
|
1993-07-30 |
1993-09-15 |
Isis Innovation |
Tag reagent and assay method
|
DK96093D0
(da)
*
|
1993-08-25 |
1993-08-25 |
Symbicom Ab |
Improvements in molecular modelling and drug design
|
CN1154640C
(zh)
*
|
1993-10-01 |
2004-06-23 |
纽约市哥伦比亚大学理事 |
用标示物编码的多元组合化学库
|
US6165778A
(en)
|
1993-11-02 |
2000-12-26 |
Affymax Technologies N.V. |
Reaction vessel agitation apparatus
|
US5503805A
(en)
|
1993-11-02 |
1996-04-02 |
Affymax Technologies N.V. |
Apparatus and method for parallel coupling reactions
|
JPH09508353A
(ja)
|
1993-11-02 |
1997-08-26 |
アフィマックス テクノロジーズ ナムローゼ フェンノートシャップ |
分子多様性の合成及びスクリーニング
|
WO1995016788A1
(en)
*
|
1993-12-17 |
1995-06-22 |
Cubicciotti Roger S |
Nucleotide-directed assembly of bimolecular and multimolecular drugs and devices
|
ZA95260B
(en)
*
|
1994-01-13 |
1995-09-28 |
Univ Columbia |
Synthetic receptors libraries and uses thereof
|
US5605793A
(en)
*
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
US5449613A
(en)
|
1994-03-01 |
1995-09-12 |
The University Of Iowa Research Foundation |
Reacting an enzyme in a non-aqueous solvent by adding a lyophilizate of enzyme and salt to the solvent
|
US6936477B2
(en)
*
|
1994-04-13 |
2005-08-30 |
The Trustees Of Columbia University In The City Of New York |
Complex combinatorial chemical libraries encoded with tags
|
US5643722A
(en)
*
|
1994-05-11 |
1997-07-01 |
Trustees Of Boston University |
Methods for the detection and isolation of proteins
|
US5663046A
(en)
|
1994-06-22 |
1997-09-02 |
Pharmacopeia, Inc. |
Synthesis of combinatorial libraries
|
AU689924B2
(en)
|
1994-06-23 |
1998-04-09 |
Affymax Technologies N.V. |
Photolabile compounds and methods for their use
|
AU697920B2
(en)
|
1994-07-26 |
1998-10-22 |
Scripps Research Institute, The |
Soluble combinatorial libraries
|
US5846719A
(en)
*
|
1994-10-13 |
1998-12-08 |
Lynx Therapeutics, Inc. |
Oligonucleotide tags for sorting and identification
|
US5604097A
(en)
*
|
1994-10-13 |
1997-02-18 |
Spectragen, Inc. |
Methods for sorting polynucleotides using oligonucleotide tags
|
US5695934A
(en)
*
|
1994-10-13 |
1997-12-09 |
Lynx Therapeutics, Inc. |
Massively parallel sequencing of sorted polynucleotides
|
US6045671A
(en)
|
1994-10-18 |
2000-04-04 |
Symyx Technologies, Inc. |
Systems and methods for the combinatorial synthesis of novel materials
|
US5985356A
(en)
|
1994-10-18 |
1999-11-16 |
The Regents Of The University Of California |
Combinatorial synthesis of novel materials
|
WO1996024847A1
(en)
|
1995-02-10 |
1996-08-15 |
Smithkline Beecham Corporation |
A process for identifiying pharmaceutically active agents using an epitope-tagged library
|
US5843650A
(en)
|
1995-05-01 |
1998-12-01 |
Segev; David |
Nucleic acid detection and amplification by chemical linkage of oligonucleotides
|
MX9708552A
(es)
|
1995-05-09 |
1997-12-31 |
Basf Ag |
(het)ariloxi-, -tio- y -aminocrotonatos, su preparacion y uso.
|
US5679519A
(en)
*
|
1995-05-09 |
1997-10-21 |
Oprandy; John J. |
Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
|
US6210900B1
(en)
*
|
1995-05-23 |
2001-04-03 |
Smithkline Beecham Corporation |
Method of encoding a series of combinatorial libraries and developing structure activity relationships
|
US5830658A
(en)
|
1995-05-31 |
1998-11-03 |
Lynx Therapeutics, Inc. |
Convergent synthesis of branched and multiply connected macromolecular structures
|
US5824471A
(en)
*
|
1995-06-05 |
1998-10-20 |
Brigham And Women's Hospital |
Detection of mismatches by cleavage of nucleic acid heteroduplexes
|
HUP9900910A2
(hu)
|
1995-06-07 |
1999-07-28 |
Lynx Therapeutics, Inc. |
Oligonukleotid jelzések osztályozáshoz és azonosításhoz
|
US5958792A
(en)
|
1995-06-07 |
1999-09-28 |
Chiron Corporation |
Combinatorial libraries of substrate-bound cyclic organic compounds
|
US5780613A
(en)
|
1995-08-01 |
1998-07-14 |
Northwestern University |
Covalent lock for self-assembled oligonucleotide constructs
|
US5795976A
(en)
*
|
1995-08-08 |
1998-08-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Detection of nucleic acid heteroduplex molecules by denaturing high-performance liquid chromatography and methods for comparative sequencing
|
US5723320A
(en)
*
|
1995-08-29 |
1998-03-03 |
Dehlinger; Peter J. |
Position-addressable polynucleotide arrays
|
US6495314B1
(en)
|
1995-09-29 |
2002-12-17 |
The Scripps Research Institute |
Process for characterizing proteins
|
DE19646372C1
(de)
|
1995-11-11 |
1997-06-19 |
Evotec Biosystems Gmbh |
Genotyp und Phänotyp koppelnde Verbindung
|
US5763175A
(en)
*
|
1995-11-17 |
1998-06-09 |
Lynx Therapeutics, Inc. |
Simultaneous sequencing of tagged polynucleotides
|
WO1997019039A1
(en)
|
1995-11-17 |
1997-05-29 |
Novartis Ag |
Solid phase synthesis of heterocyclic compounds and combinatorial compound library
|
US5763263A
(en)
*
|
1995-11-27 |
1998-06-09 |
Dehlinger; Peter J. |
Method and apparatus for producing position addressable combinatorial libraries
|
US6537776B1
(en)
|
1999-06-14 |
2003-03-25 |
Diversa Corporation |
Synthetic ligation reassembly in directed evolution
|
US6613508B1
(en)
|
1996-01-23 |
2003-09-02 |
Qiagen Genomics, Inc. |
Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
|
AU2253397A
(en)
|
1996-01-23 |
1997-08-20 |
Affymetrix, Inc. |
Nucleic acid analysis techniques
|
US5880972A
(en)
*
|
1996-02-26 |
1999-03-09 |
Pharmacopeia, Inc. |
Method and apparatus for generating and representing combinatorial chemistry libraries
|
WO1997035198A1
(en)
|
1996-03-22 |
1997-09-25 |
Ontogen Corporation |
Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
|
US6294325B1
(en)
|
1996-07-05 |
2001-09-25 |
The Mount Sinai School Of Medicine Of The City University Of New York |
Cloning and expression of thermostable multi genes and proteins and uses thereof
|
US5821356A
(en)
*
|
1996-08-12 |
1998-10-13 |
The Perkin Elmer Corporation |
Propargylethoxyamino nucleotides
|
US6355490B1
(en)
*
|
1996-09-13 |
2002-03-12 |
Jill Edie Hochlowski |
Attached tags for use in combinatorial chemistry synthesis
|
DE19642751A1
(de)
|
1996-10-16 |
1998-04-23 |
Deutsches Krebsforsch |
Saccharid-Bibliothek
|
US5954874A
(en)
|
1996-10-17 |
1999-09-21 |
Hunter; Charles Eric |
Growth of bulk single crystals of aluminum nitride from a melt
|
US6261804B1
(en)
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
ATE332368T1
(de)
|
1997-01-21 |
2006-07-15 |
Gen Hospital Corp |
Selektion von proteinen mittels rns-protein fusionen
|
US6127533A
(en)
|
1997-02-14 |
2000-10-03 |
Isis Pharmaceuticals, Inc. |
2'-O-aminooxy-modified oligonucleotides
|
US5739314A
(en)
|
1997-04-25 |
1998-04-14 |
Hybridon, Inc. |
Method for synthesizing 2'-O-substituted pyrimidine nucleosides
|
DE69818458T3
(de)
|
1997-05-28 |
2009-12-17 |
Crescendo Biologics Ltd., Babraham |
Ribosom-komplexe als selektionspartikel für die in vitro anzeige und evolution von proteinen
|
US6969584B2
(en)
|
1997-06-12 |
2005-11-29 |
Rigel Pharmaceuticals, Inc. |
Combinatorial enzymatic complexes
|
AU8147798A
(en)
|
1997-06-16 |
1999-01-04 |
University Of North Carolina At Chapel Hill, The |
Peptido oligonucleotides (pons) and their combinatorial libraries
|
US6607878B2
(en)
|
1997-10-06 |
2003-08-19 |
Stratagene |
Collections of uniquely tagged molecules
|
US6348322B1
(en)
|
1997-10-17 |
2002-02-19 |
Duke University |
Method of screening for specific binding interactions
|
US20030004122A1
(en)
|
1997-11-05 |
2003-01-02 |
Leonid Beigelman |
Nucleotide triphosphates and their incorporation into oligonucleotides
|
US6232066B1
(en)
*
|
1997-12-19 |
2001-05-15 |
Neogen, Inc. |
High throughput assay system
|
EP1056882A4
(en)
|
1998-02-21 |
2002-04-17 |
Technology Foundation Wisys |
ONE-DIMENSIONAL CHEMICAL COMPOUND ARRAYS AND METHODS FOR ANALYZING THE SAME
|
US6316616B1
(en)
|
1998-04-02 |
2001-11-13 |
President And Fellows Of Harvard College |
Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
|
ATE340870T1
(de)
|
1998-04-03 |
2006-10-15 |
Compound Therapeutics Inc |
Adressierbare protein arrays
|
WO1999054458A1
(en)
|
1998-04-17 |
1999-10-28 |
Whitehead Institute For Biomedical Research |
Use of a ribozyme to join nucleic acids and peptides
|
AU3943799A
(en)
|
1998-05-15 |
1999-12-06 |
Isis Innovation Limited |
Reagent and method
|
US6287765B1
(en)
|
1998-05-20 |
2001-09-11 |
Molecular Machines, Inc. |
Methods for detecting and identifying single molecules
|
US6096875A
(en)
*
|
1998-05-29 |
2000-08-01 |
The Perlein-Elmer Corporation |
Nucleotide compounds including a rigid linker
|
US5948648A
(en)
*
|
1998-05-29 |
1999-09-07 |
Khan; Shaheer H. |
Nucleotide compounds including a rigid linker
|
MXPA00012237A
(es)
|
1998-06-10 |
2002-11-15 |
Glycodesign Inc |
Biblioteca de compuestos combinatorios derigidos y ensayos de alto rendimiento para seleccionar los mismos.
|
GB0002310D0
(en)
|
2000-02-01 |
2000-03-22 |
Solexa Ltd |
Polynucleotide sequencing
|
AU6502599A
(en)
|
1998-10-05 |
2000-04-26 |
Lynx Therapeutics, Inc. |
Enzymatic synthesis of oligonucleotide tags
|
AU6295999A
(en)
|
1998-10-09 |
2000-05-01 |
Pharmacopeia, Inc. |
Selecting codes to be used for encoding combinatorial libraries
|
US6175001B1
(en)
|
1998-10-16 |
2001-01-16 |
The Scripps Research Institute |
Functionalized pyrimidine nucleosides and nucleotides and DNA's incorporating same
|
AU1318400A
(en)
*
|
1998-10-19 |
2000-05-08 |
Board Of Trustees Of The Leland Stanford Junior University |
Dna-templated combinatorial library chemistry
|
CN1325445A
(zh)
|
1998-10-28 |
2001-12-05 |
诺维信公司 |
制备基因库的方法
|
US5942609A
(en)
|
1998-11-12 |
1999-08-24 |
The Porkin-Elmer Corporation |
Ligation assembly and detection of polynucleotides on solid-support
|
WO2000032823A1
(en)
|
1998-12-02 |
2000-06-08 |
Phylos, Inc. |
Dna-protein fusions and uses thereof
|
US6087112A
(en)
|
1998-12-30 |
2000-07-11 |
Oligos Etc. Inc. |
Arrays with modified oligonucleotide and polynucleotide compositions
|
WO2000040695A2
(en)
|
1999-01-08 |
2000-07-13 |
Ceres, Inc. |
Sequence-determined dna fragments and corresponding polypeptides encoded thereby
|
US6831071B2
(en)
|
1999-04-08 |
2004-12-14 |
Pavel Sergeev |
Synthesis of biologically active compounds in cells
|
AU7569600A
(en)
|
1999-05-20 |
2000-12-28 |
Illumina, Inc. |
Combinatorial decoding of random nucleic acid arrays
|
CA2376623C
(en)
|
1999-06-25 |
2011-04-19 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
ES2383332T3
(es)
|
1999-07-27 |
2012-06-20 |
Bristol-Myers Squibb Company |
Procedimiento de ligación de aceptores de péptidos
|
DE60002821T2
(de)
|
1999-08-27 |
2004-05-06 |
Japan Science And Technology Corp., Kawaguchi |
Reversibel photokuppelnde nukleinsäure und phosphoramidit
|
GB9920194D0
(en)
|
1999-08-27 |
1999-10-27 |
Advanced Biotech Ltd |
A heat-stable thermostable DNA polymerase for use in nucleic acid amplification
|
US6274320B1
(en)
|
1999-09-16 |
2001-08-14 |
Curagen Corporation |
Method of sequencing a nucleic acid
|
US20020048760A1
(en)
*
|
1999-12-10 |
2002-04-25 |
Hyseq, Inc. |
Use of mismatch cleavage to detect complementary probes
|
ATE322558T1
(de)
|
2000-01-24 |
2006-04-15 |
Compound Therapeutics Inc |
Sensible und multiplexe diagnostische tests zur proteinanalyse
|
EP1254367A4
(en)
|
2000-02-03 |
2006-07-05 |
Nanoscale Combinatorial Synthe |
METHOD FOR IDENTIFYING STRUCTURES BY MASS DETERMINATION
|
US20020127598A1
(en)
|
2000-03-27 |
2002-09-12 |
Wenqiang Zhou |
Solution-phase combinatorial library synthesis and pharmaceutically active compounds produced thereby
|
US6368801B1
(en)
*
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
US7682837B2
(en)
|
2000-05-05 |
2010-03-23 |
Board Of Trustees Of Leland Stanford Junior University |
Devices and methods to form a randomly ordered array of magnetic beads and uses thereof
|
CA2409305C
(en)
|
2000-05-19 |
2011-01-11 |
Richard B. Williams |
In vitro evolution of nucleic acids and encoded polypeptide
|
US7244560B2
(en)
|
2000-05-21 |
2007-07-17 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
US20020055125A1
(en)
*
|
2000-06-05 |
2002-05-09 |
Chiron Corporation |
Microarrays for performing proteomic analyses
|
US20020115068A1
(en)
|
2000-06-23 |
2002-08-22 |
Ian Tomlinson |
Matrix screening method
|
WO2002003067A1
(en)
|
2000-07-03 |
2002-01-10 |
Merck & Co., Inc. |
Methods for encoding combinatorial libraries
|
US6811977B2
(en)
|
2000-07-27 |
2004-11-02 |
California Institute Of Technology |
Rapid, quantitative method for the mass spectrometric analysis of nucleic acids for gene expression and genotyping
|
US20020072887A1
(en)
*
|
2000-08-18 |
2002-06-13 |
Sandor Szalma |
Interaction fingerprint annotations from protein structure models
|
US20020107302A1
(en)
|
2000-09-08 |
2002-08-08 |
Escano Nelson Zamora |
Monomeric dye inkjet printing ink formulations for invisible marking / identification
|
WO2004007529A2
(en)
|
2002-07-15 |
2004-01-22 |
The Trustees Of Princeton University |
Iap binding compounds
|
US20020146723A1
(en)
|
2000-10-25 |
2002-10-10 |
Krontiris Theodore G. |
Candidate region mismatch scanning for genotyping and mutation detection
|
JP2002315577A
(ja)
|
2000-11-14 |
2002-10-29 |
Gencom Co |
核酸ライブラリーの作製方法
|
ES2271306T5
(es)
*
|
2001-03-19 |
2013-10-16 |
President And Fellows Of Harvard College |
Evolución de una nueva función molecular
|
WO2002074978A2
(en)
|
2001-03-19 |
2002-09-26 |
President And Fellows Of Harvard College |
Nucleic acid shuffling
|
WO2002083951A1
(en)
|
2001-04-10 |
2002-10-24 |
Northeastern University |
Multiplexed ligand/protein binding assays with pna labels
|
EP1383921A2
(en)
|
2001-05-03 |
2004-01-28 |
Warnex Research Inc. |
A molecular tag code for monitoring a product and process using same
|
US7838270B2
(en)
|
2001-05-22 |
2010-11-23 |
The University Of Chicago |
Target-dependent transcription using deletion mutants of N4 RNA polymerase
|
WO2002099078A2
(en)
|
2001-06-05 |
2002-12-12 |
Irm Llc |
Functional proteomic profiling
|
NZ530098A
(en)
|
2001-06-20 |
2006-02-24 |
Nuevolution As |
Templated molecules and methods for using such molecules
|
US20060234231A1
(en)
*
|
2001-06-20 |
2006-10-19 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
WO2004001042A2
(en)
|
2002-06-20 |
2003-12-31 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
WO2002102820A1
(en)
|
2001-06-20 |
2002-12-27 |
Nuevolution A/S |
Nucleoside derivatives for library preparation
|
US20040161741A1
(en)
*
|
2001-06-30 |
2004-08-19 |
Elazar Rabani |
Novel compositions and processes for analyte detection, quantification and amplification
|
DE10145226A1
(de)
|
2001-09-13 |
2003-04-10 |
Lifebits Ag |
Herstellung von trägergebundenen Molekülen
|
CA2466164A1
(en)
|
2001-10-30 |
2003-05-08 |
Nanomics Biosystems Pty, Ltd. |
Device and methods for directed synthesis of chemical libraries
|
WO2003062417A1
(fr)
|
2002-01-22 |
2003-07-31 |
Mitsubishi Chemical Corporation |
Produit de ligation arn-adn, et utilisation correspondante
|
ATE424561T1
(de)
|
2002-03-08 |
2009-03-15 |
Eidgenoess Tech Hochschule |
Kodierte, selbst-assemblierende chemische bibliotheken (esachel)
|
US20050247001A1
(en)
*
|
2002-03-15 |
2005-11-10 |
Nuevolution A/S |
Building block forming a c-c or a c-hetero atom bond uponreaction
|
WO2003078050A2
(en)
|
2002-03-15 |
2003-09-25 |
Nuevolution A/S |
A building block forming a c-c bond upon reaction
|
WO2003078626A2
(en)
*
|
2002-03-15 |
2003-09-25 |
Nuevolution A/S |
A building block capable of transferring a functional entity
|
EP1487848A2
(en)
|
2002-03-15 |
2004-12-22 |
Nuevolution A/S |
A building block forming a c=c double bond upon reaction
|
DK1487978T3
(da)
*
|
2002-03-15 |
2009-03-23 |
Nuevolution As |
Forbedret fremgangsmåde til syntese af templatemolekyler
|
AU2003226008A1
(en)
|
2002-03-22 |
2003-10-13 |
Emory University |
Template-driven processes for synthesizing polymers and components related to such processes
|
KR101048279B1
(ko)
|
2002-05-30 |
2011-07-13 |
더 스크립스 리서치 인스티튜트 |
구리 촉매 작용하에서의 아지드와 아세틸렌과의 리게이션
|
GB0213816D0
(en)
|
2002-06-14 |
2002-07-24 |
Univ Aston |
Method of producing DNA and protein libraries
|
AU2003242516A1
(en)
|
2002-07-23 |
2004-02-09 |
Nuevolution A/S |
Gene shuffling by template switching
|
EP1539980B1
(en)
*
|
2002-08-01 |
2016-02-17 |
Nuevolution A/S |
Library of complexes comprising small non-peptide molecules and double-stranded oligonucleotides identifying the molecules
|
JP4657919B2
(ja)
*
|
2002-08-19 |
2011-03-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
進化する新しい分子機能
|
US20040197845A1
(en)
|
2002-08-30 |
2004-10-07 |
Arjang Hassibi |
Methods and apparatus for pathogen detection, identification and/or quantification
|
AU2003260291A1
(en)
|
2002-09-12 |
2004-04-30 |
Nuevolution A/S |
Proximity-aided synthesis of templated molecules
|
AU2003279089A1
(en)
*
|
2002-09-30 |
2004-04-19 |
Parallele Bioscience, Inc. |
Polynucleotide synthesis and labeling by kinetic sampling ligation
|
EP1558744B1
(en)
*
|
2002-10-30 |
2011-06-15 |
Nuevolution A/S |
Enzymatic encoding
|
WO2004039962A2
(en)
|
2002-10-30 |
2004-05-13 |
Pointilliste, Inc. |
Methods for producing polypeptide-tagged collections and capture systems containing the tagged polypeptides
|
US7413857B2
(en)
*
|
2002-11-21 |
2008-08-19 |
Epicentre Technologies |
Methods for using riboprimers for strand displacement replication of target sequences
|
US20040197804A1
(en)
|
2002-12-03 |
2004-10-07 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
WO2004056994A2
(en)
|
2002-12-19 |
2004-07-08 |
Nuevolution A/S |
Quasirandom structure and function guided synthesis methods
|
JP4480715B2
(ja)
|
2003-01-29 |
2010-06-16 |
454 コーポレーション |
二重末端シーケンシング
|
WO2004074501A2
(en)
*
|
2003-02-21 |
2004-09-02 |
Nuevolution A/S |
A method for obtaining structural information about an encoded molecule
|
WO2004074429A2
(en)
*
|
2003-02-21 |
2004-09-02 |
Nuevolution A/S |
Method for producing second-generation library
|
JP4054871B2
(ja)
|
2003-02-24 |
2008-03-05 |
独立行政法人産業技術総合研究所 |
耐熱性dnaリガーゼ
|
WO2004083427A2
(en)
|
2003-03-20 |
2004-09-30 |
Nuevolution A/S |
Ligational encoding of small molecules
|
WO2004099441A2
(en)
|
2003-05-09 |
2004-11-18 |
Hyscite Discovery As |
Selection and evolution of chemical libraries
|
WO2004110964A2
(en)
|
2003-06-16 |
2004-12-23 |
Nuevolution A/S |
Encoded molecules by translation (emt)
|
WO2005003778A2
(en)
|
2003-07-02 |
2005-01-13 |
Nuevolution A/S |
A method for identifying a synthetic molecule having affinity towards a target
|
WO2005008240A2
(en)
*
|
2003-07-03 |
2005-01-27 |
Biogen Idec Ma Inc. |
STRUCTURAL INTERACTION FINGERPRINT (SIFt)
|
EP1533385A1
(en)
|
2003-09-05 |
2005-05-25 |
Nuevolution A/S |
Templated compounds for generation of encoded molecules and directional methods using such compounds
|
US11118215B2
(en)
*
|
2003-09-18 |
2021-09-14 |
Nuevolution A/S |
Method for obtaining structural information concerning an encoded molecule and method for selecting compounds
|
US7972994B2
(en)
*
|
2003-12-17 |
2011-07-05 |
Glaxosmithkline Llc |
Methods for synthesis of encoded libraries
|
EP2366705A1
(en)
*
|
2003-12-17 |
2011-09-21 |
Praecis Pharmaceuticals Incorporated |
Methods for synthesis of encoded libraries
|
US20090239211A1
(en)
*
|
2004-02-17 |
2009-09-24 |
Nuevolution A/S |
Method For Enrichment Involving Elimination By Mismatch Hybridisation
|
US20050208503A1
(en)
*
|
2004-03-16 |
2005-09-22 |
Handy Yowanto |
Chemical ligation of nucleic acids
|
EP1730277B1
(en)
*
|
2004-03-22 |
2009-10-28 |
Nuevolution A/S |
Ligational encoding using building block oligonucleotides
|
GB2413796B
(en)
|
2004-03-25 |
2006-03-29 |
Global Genomics Ab |
Methods and means for nucleic acid sequencing
|
WO2005116213A2
(en)
|
2004-04-15 |
2005-12-08 |
President And Fellows Of Harvard College |
Directed evolution of proteins
|
DE602005012139D1
(de)
*
|
2004-11-08 |
2009-02-12 |
Vipergen Aps |
Strukturelle nukleinsäure-geführte chemische synthese
|
ATE420170T1
(de)
|
2004-11-22 |
2009-01-15 |
Peter Birk Rasmussen |
Matrizengerichtete split-and-mix-synthese von bibliotheken kleiner moleküle
|
EA019420B1
(ru)
|
2004-12-20 |
2014-03-31 |
Дженентех, Инк. |
Пирролидиновые ингибиторы иап (ингибиторов апоптоза)
|
CN101107357B
(zh)
|
2005-01-21 |
2013-01-02 |
哈佛大学校长及研究员协会 |
用于以核酸为模板的合成中的游离反应物
|
US7968289B2
(en)
|
2005-05-03 |
2011-06-28 |
Ensemble Therapeutics Corporation |
Turn over probes and use thereof for nucleic acid detection
|
CA2610027A1
(en)
|
2005-05-26 |
2006-11-30 |
Ensemble Discovery Corporation |
Biodetection by nucleic acid-templated chemistry
|
WO2006130669A2
(en)
|
2005-05-31 |
2006-12-07 |
Ensemble Discovery Corporation |
Anchor-assisted fragment selection and directed assembly
|
US20090203530A1
(en)
|
2005-06-07 |
2009-08-13 |
Liu David R |
Polymer evolution via templated synthesis
|
ATE461279T1
(de)
|
2005-06-07 |
2010-04-15 |
Harvard College |
Geordnete mehrschrittsynthese mittels nukleinsäurevermittelter chemie
|
PT1910538E
(pt)
*
|
2005-06-09 |
2011-07-28 |
Praecis Pharm Inc |
Métodos para a síntese de bibliotecas codificadas
|
US8183178B2
(en)
|
2005-06-17 |
2012-05-22 |
President And Fellows Of Harvard College |
Iterated branching reaction pathways via nucleic acid-mediated chemistry
|
US20090035824A1
(en)
*
|
2005-06-17 |
2009-02-05 |
Liu David R |
Nucleic acid-templated chemistry in organic solvents
|
WO2007011722A2
(en)
|
2005-07-15 |
2007-01-25 |
President And Fellows Of Harvard College |
Reaction discovery system
|
WO2007016488A2
(en)
|
2005-07-29 |
2007-02-08 |
Ensemble Discovery Corporation |
Analysis of encoded chemical libraries
|
EP2368868A1
(en)
*
|
2005-10-28 |
2011-09-28 |
Praecis Pharmaceuticals Inc. |
Methods for identifying compounds of interest using encoded libraries
|
LT3018206T
(lt)
|
2005-12-01 |
2021-12-10 |
Nuevolution A/S |
Fermentiniai kodavimo būdai, skirti didelių bibliotekų efektyviai sintezei
|
EP2021470A1
(en)
|
2006-05-03 |
2009-02-11 |
Vipergen APS |
A method for preparing compounds by nucleic acid directed synthesis
|
WO2008014238A2
(en)
|
2006-07-24 |
2008-01-31 |
Tetralogic Pharmaceuticals Corporation |
Dimeric iap inhibitors
|
WO2008036273A2
(en)
|
2006-09-18 |
2008-03-27 |
Ensemble Discovery Corporation |
Receptor family profiling
|
EP2066813A2
(en)
|
2006-09-28 |
2009-06-10 |
Ensemble Discovery Corporation |
Compositions and methods for biodetection by nucleic acid-templated chemistry
|
WO2008094599A2
(en)
|
2007-01-30 |
2008-08-07 |
Rockefeller University, The |
Modified rna ligase for efficient 3' modification of rna
|
GB0712245D0
(en)
*
|
2007-06-25 |
2007-08-01 |
Cythera Technologies Ltd |
Combinatorial libraries and related methods
|
CA2730565A1
(en)
|
2007-07-27 |
2009-02-05 |
Ensemble Discovery Corporation |
Detection assays and use thereof
|
WO2009077173A2
(en)
|
2007-12-19 |
2009-06-25 |
Philochem Ag |
Dna-encoded chemical libraries
|
TW201011006A
(en)
*
|
2008-06-16 |
2010-03-16 |
Nuevolution As |
IAP binding compounds
|
SI2558577T1
(sl)
|
2010-04-16 |
2019-05-31 |
Nuevolution A/S |
Bifunkcionalni kompleksi in metode za pripravo in uporabo takšnih kompleksov
|
US10597650B2
(en)
*
|
2012-12-21 |
2020-03-24 |
New England Biolabs, Inc. |
Ligase activity
|