AU2003260291A1 - Proximity-aided synthesis of templated molecules - Google Patents

Proximity-aided synthesis of templated molecules

Info

Publication number
AU2003260291A1
AU2003260291A1 AU2003260291A AU2003260291A AU2003260291A1 AU 2003260291 A1 AU2003260291 A1 AU 2003260291A1 AU 2003260291 A AU2003260291 A AU 2003260291A AU 2003260291 A AU2003260291 A AU 2003260291A AU 2003260291 A1 AU2003260291 A1 AU 2003260291A1
Authority
AU
Australia
Prior art keywords
proximity
templated molecules
aided synthesis
aided
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003260291A
Other versions
AU2003260291A8 (en
Inventor
Thomas Franch
Thomas Thisted
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuevolution AS
Original Assignee
Nuevolution AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution AS filed Critical Nuevolution AS
Publication of AU2003260291A1 publication Critical patent/AU2003260291A1/en
Publication of AU2003260291A8 publication Critical patent/AU2003260291A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Wind Motors (AREA)
AU2003260291A 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules Abandoned AU2003260291A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40996802P 2002-09-12 2002-09-12
DKPA200201347 2002-09-12
DKPA200201347 2002-09-12
US60/409,968 2002-09-12
PCT/DK2003/000590 WO2004024929A2 (en) 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules

Publications (2)

Publication Number Publication Date
AU2003260291A1 true AU2003260291A1 (en) 2004-04-30
AU2003260291A8 AU2003260291A8 (en) 2004-04-30

Family

ID=31995414

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003260291A Abandoned AU2003260291A1 (en) 2002-09-12 2003-09-12 Proximity-aided synthesis of templated molecules

Country Status (3)

Country Link
EP (1) EP1539953A2 (en)
AU (1) AU2003260291A1 (en)
WO (1) WO2004024929A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401850A1 (en) 2001-06-20 2004-03-31 Nuevolution A/S Nucleoside derivatives for library preparation
IL163822A0 (en) 2002-03-15 2005-12-18 Nuevolution As An improved method for synthesising templated molecules
WO2004013070A2 (en) 2002-08-01 2004-02-12 Nuevolution A/S Multi-step synthesis of templated molecules
WO2004039825A2 (en) 2002-10-30 2004-05-13 Nuevolution A/S Method for the synthesis of a bifunctional complex
AU2011226815B2 (en) * 2002-10-30 2014-09-25 Nuevolution A/S Enzymatic encoding
AU2003291964A1 (en) 2002-12-19 2004-07-14 Nuevolution A/S Quasirandom structure and function guided synthesis methods
WO2004074429A2 (en) 2003-02-21 2004-09-02 Nuevolution A/S Method for producing second-generation library
ATE424455T1 (en) 2003-03-20 2009-03-15 Nuevolution As LIGATION-MEDIATING CODING OF SMALL MOLECULES
EP1670939B1 (en) * 2003-09-18 2009-11-04 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
US7972994B2 (en) 2003-12-17 2011-07-05 Glaxosmithkline Llc Methods for synthesis of encoded libraries
RU2470077C2 (en) 2003-12-17 2012-12-20 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Biologically active compound containing coding oligonucleotide (versions), method for synthesis thereof, library of compounds (versions), method for synthesis thereof, and method of searching for compound bound with biological target (versions)
US7704925B2 (en) 2004-03-22 2010-04-27 Nuevolution A/S Ligational encoding using building block oligonucleotides
EP1809743B1 (en) * 2004-11-08 2008-12-31 Vipergen APS Structural nucleid acid guided chemical synthesis
US8183178B2 (en) 2005-06-17 2012-05-22 President And Fellows Of Harvard College Iterated branching reaction pathways via nucleic acid-mediated chemistry
AU2006309096B2 (en) 2005-10-28 2013-07-04 Glaxosmithkline Llc Methods for identifying compounds of interest using encoded libraries
LT2336315T (en) 2005-12-01 2017-11-10 Nuevolution A/S Enzymatic encoding methods for efficient synthesis of large libraries
WO2010094036A1 (en) 2009-02-13 2010-08-19 X-Chem, Inc. Methods of creating and screening dna-encoded libraries
SI2558577T1 (en) 2010-04-16 2019-05-31 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes
DK2748357T3 (en) 2011-09-07 2018-07-16 X Chem Inc Methods for labeling DNA-encoded libraries
CA2879018A1 (en) 2012-07-13 2014-01-16 X-Chem, Inc. Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
WO2020051452A2 (en) * 2018-09-07 2020-03-12 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Hiv or hcv detection with crispr-cas13a

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US7479472B1 (en) * 1998-10-19 2009-01-20 The Board Of Trustees Of The Leland Stanford Junior University DNA-templated combinatorial library chemistry
US7070928B2 (en) * 2001-03-19 2006-07-04 President And Fellows Of Harvard College Evolving new molecular function
IL163822A0 (en) * 2002-03-15 2005-12-18 Nuevolution As An improved method for synthesising templated molecules

Also Published As

Publication number Publication date
AU2003260291A8 (en) 2004-04-30
EP1539953A2 (en) 2005-06-15
WO2004024929A3 (en) 2004-05-06
WO2004024929A2 (en) 2004-03-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase