HK1245329A1 - 用於高效合成大文庫的酶編碼方法 - Google Patents

用於高效合成大文庫的酶編碼方法

Info

Publication number
HK1245329A1
HK1245329A1 HK18104814.6A HK18104814A HK1245329A1 HK 1245329 A1 HK1245329 A1 HK 1245329A1 HK 18104814 A HK18104814 A HK 18104814A HK 1245329 A1 HK1245329 A1 HK 1245329A1
Authority
HK
Hong Kong
Prior art keywords
encoding methods
large libraries
efficient synthesis
enzymatic encoding
enzymatic
Prior art date
Application number
HK18104814.6A
Other languages
English (en)
Inventor
Thomas Franch
Mikkel Dybro Lundorf
Søren Nyboe Jakobsen
Eva Kampmann Olsen
Anne Lee Andersen
Anette Holtmann
Anders Holm Hansen
Anders Malling Sørensen
Anne Goldbech
Ditte Kievsmose Kaldor
Leon Dean De
Frank Abildgaard Sløk
Gitte Nystrup Husemoen
Johannes Dolberg
Kim Birkebaek Jensen
Lene Petersen
Mads Nørregaard-Madsen
Michael Anders Godskesen
Sanne Schrøder Glad
Søren Neve
Christian Klarner Sams
Thomas Thisted
Alex Haahr Gouliaev
Tine Titiola Akinleminu Kronberg
Per-Ola Freskgard
Henrik Pedersen
Jakob Felding
Original Assignee
Nuevolution As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution As filed Critical Nuevolution As
Publication of HK1245329A1 publication Critical patent/HK1245329A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/04—Methods of creating libraries, e.g. combinatorial synthesis using dynamic combinatorial chemistry techniques
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
HK18104814.6A 2005-12-01 2018-04-12 用於高效合成大文庫的酶編碼方法 HK1245329A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200501704 2005-12-01
US74149005P 2005-12-02 2005-12-02

Publications (1)

Publication Number Publication Date
HK1245329A1 true HK1245329A1 (zh) 2018-08-24

Family

ID=38001974

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18104814.6A HK1245329A1 (zh) 2005-12-01 2018-04-12 用於高效合成大文庫的酶編碼方法

Country Status (12)

Country Link
US (4) US9574189B2 (zh)
EP (5) EP3305900B1 (zh)
AT (1) ATE490318T1 (zh)
DE (1) DE602006018648D1 (zh)
DK (5) DK2341140T3 (zh)
ES (2) ES2901551T3 (zh)
HK (1) HK1245329A1 (zh)
HU (1) HUE056836T2 (zh)
LT (4) LT2336315T (zh)
PT (2) PT3305900T (zh)
SI (4) SI3018206T1 (zh)
WO (1) WO2007062664A2 (zh)

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