AU7564296A - Solid phase synthesis of heterocyclic compounds and combinatorial compound library - Google Patents

Solid phase synthesis of heterocyclic compounds and combinatorial compound library

Info

Publication number
AU7564296A
AU7564296A AU75642/96A AU7564296A AU7564296A AU 7564296 A AU7564296 A AU 7564296A AU 75642/96 A AU75642/96 A AU 75642/96A AU 7564296 A AU7564296 A AU 7564296A AU 7564296 A AU7564296 A AU 7564296A
Authority
AU
Australia
Prior art keywords
solid phase
phase synthesis
heterocyclic compounds
compound library
combinatorial compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU75642/96A
Inventor
Eduard Felder
Andreas Marzinzik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU7564296A publication Critical patent/AU7564296A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Structural Engineering (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU75642/96A 1995-11-17 1996-11-05 Solid phase synthesis of heterocyclic compounds and combinatorial compound library Abandoned AU7564296A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95810717 1995-11-17
EP95810717 1995-11-17
PCT/EP1996/004808 WO1997019039A1 (en) 1995-11-17 1996-11-05 Solid phase synthesis of heterocyclic compounds and combinatorial compound library

Publications (1)

Publication Number Publication Date
AU7564296A true AU7564296A (en) 1997-06-11

Family

ID=8221818

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75642/96A Abandoned AU7564296A (en) 1995-11-17 1996-11-05 Solid phase synthesis of heterocyclic compounds and combinatorial compound library

Country Status (2)

Country Link
AU (1) AU7564296A (en)
WO (1) WO1997019039A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114316B2 (en) 2004-08-21 2012-02-14 Merck Patent Gmbh Monomers, oligomers and polymers of thieno[2,3-b]thiophene

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
NZ505902A (en) 1998-01-23 2003-08-29 Upjohn Co Oxazolidinone compounds useful as antimicrobial agents and combinatorial libraries
DE19904406A1 (en) * 1999-02-04 2000-08-10 Bayer Ag Substituted pyrazole carboxylic acids
DE19904396A1 (en) * 1999-02-04 2000-08-10 Bayer Ag Substituted pyrazolbenzylamine derivatives
DE19904389A1 (en) * 1999-02-04 2000-08-10 Bayer Ag Use of substituted isoxazolecarboxylic acids and derivatives and new substances
DE19904397A1 (en) * 1999-02-04 2000-08-10 Bayer Ag Use of pyrazole carboxamides
WO2001049678A1 (en) 1999-12-30 2001-07-12 H. Lundbeck A/S Substituted phenyl-piperazine derivatives, their preparation and use
JP2003519227A (en) * 1999-12-30 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット Method for producing substituted benzene derivative
EP1401850A1 (en) 2001-06-20 2004-03-31 Nuevolution A/S Nucleoside derivatives for library preparation
CN101006177B (en) 2002-03-15 2011-10-12 纽韦卢森公司 An improved method for synthesising templated molecules
US10730906B2 (en) 2002-08-01 2020-08-04 Nuevolutions A/S Multi-step synthesis of templated molecules
ES2640279T3 (en) 2002-10-30 2017-11-02 Nuevolution A/S Procedure for the synthesis of a bifunctional complex
US9121110B2 (en) 2002-12-19 2015-09-01 Nuevolution A/S Quasirandom structure and function guided synthesis methods
WO2004074429A2 (en) 2003-02-21 2004-09-02 Nuevolution A/S Method for producing second-generation library
DE602004023960D1 (en) 2003-09-18 2009-12-17 Nuevolution As Method for obtaining structural information of encoded molecules and for selection of compounds
SI2341140T1 (en) 2005-12-01 2017-12-29 Nuevolution A/S Enzymatic encoding methods for efficient synthesis of large libraries
CN101062916B (en) * 2006-04-29 2012-12-26 中国人民解放军军事医学科学院毒物药物研究所 Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof
LT2558577T (en) 2010-04-16 2019-03-12 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3948937A (en) * 1972-02-29 1976-04-06 E. I. Du Pont De Nemours And Company Pyrazole plant growth regulants
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114316B2 (en) 2004-08-21 2012-02-14 Merck Patent Gmbh Monomers, oligomers and polymers of thieno[2,3-b]thiophene

Also Published As

Publication number Publication date
WO1997019039A1 (en) 1997-05-29

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