SI1896485T1 - Derivati azolopiridin ona kot inhibitorji lipazin fosfolipaz - Google Patents

Derivati azolopiridin ona kot inhibitorji lipazin fosfolipaz

Info

Publication number
SI1896485T1
SI1896485T1 SI200630748T SI200630748T SI1896485T1 SI 1896485 T1 SI1896485 T1 SI 1896485T1 SI 200630748 T SI200630748 T SI 200630748T SI 200630748 T SI200630748 T SI 200630748T SI 1896485 T1 SI1896485 T1 SI 1896485T1
Authority
SI
Slovenia
Prior art keywords
azolopyridine
lipase
derivatives
phospholipase inhibitors
phospholipase
Prior art date
Application number
SI200630748T
Other languages
English (en)
Inventor
Gerhard Zoller
Stefan Petry
Gunter Muller
Hubert Heuer
Norbert Tennagels
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of SI1896485T1 publication Critical patent/SI1896485T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI200630748T 2005-06-09 2006-05-27 Derivati azolopiridin ona kot inhibitorji lipazin fosfolipaz SI1896485T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005026762A DE102005026762A1 (de) 2005-06-09 2005-06-09 Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
EP06753937A EP1896485B1 (de) 2005-06-09 2006-05-27 Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen
PCT/EP2006/005095 WO2006131231A1 (de) 2005-06-09 2006-05-27 Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen

Publications (1)

Publication Number Publication Date
SI1896485T1 true SI1896485T1 (sl) 2010-09-30

Family

ID=37076291

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200630748T SI1896485T1 (sl) 2005-06-09 2006-05-27 Derivati azolopiridin ona kot inhibitorji lipazin fosfolipaz

Country Status (30)

Country Link
US (2) US7846943B2 (sl)
EP (1) EP1896485B1 (sl)
JP (1) JP2008542410A (sl)
KR (1) KR20080019215A (sl)
CN (1) CN101193896A (sl)
AR (1) AR054132A1 (sl)
AT (1) ATE468342T1 (sl)
AU (1) AU2006257022A1 (sl)
BR (1) BRPI0611688A2 (sl)
CA (1) CA2610325A1 (sl)
CY (1) CY1110213T1 (sl)
DE (2) DE102005026762A1 (sl)
DK (1) DK1896485T3 (sl)
ES (1) ES2346561T3 (sl)
HR (1) HRP20100409T1 (sl)
IL (1) IL187730A0 (sl)
MA (1) MA29481B1 (sl)
MX (1) MX2007015347A (sl)
MY (1) MY142792A (sl)
NO (1) NO20080133L (sl)
NZ (1) NZ564063A (sl)
PL (1) PL1896485T3 (sl)
PT (1) PT1896485E (sl)
RS (1) RS51268B (sl)
RU (1) RU2414473C2 (sl)
SI (1) SI1896485T1 (sl)
TW (1) TW200716653A (sl)
UY (1) UY29593A1 (sl)
WO (1) WO2006131231A1 (sl)
ZA (1) ZA200709501B (sl)

Families Citing this family (8)

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DE102006014685A1 (de) 2006-03-28 2007-10-04 Sanofi-Aventis Imidazo-pyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholiphasen
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
TW201014822A (en) 2008-07-09 2010-04-16 Sanofi Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
JP5605844B2 (ja) 2008-10-17 2014-10-15 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有する酢酸アミド誘導体
BR112012010010A2 (pt) * 2009-10-29 2018-03-20 Sirtris Pharmaceuticals Inc piridinas bicíclicas e análogos como moduladores da sirtuína
KR20120123325A (ko) 2009-12-15 2012-11-08 시오노기세야쿠 가부시키가이샤 혈관 내피 리파아제 저해 활성을 갖는 옥사디아졸 유도체
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
CN114560873B (zh) * 2021-12-27 2023-02-28 浙江日出药业有限公司 一种3-氯甲基-6-氯-噁唑[4,5-b]吡啶-2(3H)酮的制备方法

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Also Published As

Publication number Publication date
US20110039883A1 (en) 2011-02-17
DE102005026762A1 (de) 2006-12-21
EP1896485A1 (de) 2008-03-12
ATE468342T1 (de) 2010-06-15
RU2007145499A (ru) 2009-06-20
ES2346561T3 (es) 2010-10-18
RU2414473C2 (ru) 2011-03-20
CA2610325A1 (en) 2006-12-14
HRP20100409T1 (hr) 2010-09-30
RS51268B (sr) 2010-12-31
NZ564063A (en) 2010-07-30
KR20080019215A (ko) 2008-03-03
DE502006006986D1 (de) 2010-07-01
BRPI0611688A2 (pt) 2010-09-28
MX2007015347A (es) 2008-02-15
WO2006131231A1 (de) 2006-12-14
TW200716653A (en) 2007-05-01
CN101193896A (zh) 2008-06-04
AR054132A1 (es) 2007-06-06
IL187730A0 (en) 2008-08-07
MY142792A (en) 2010-12-31
PT1896485E (pt) 2010-08-05
US7846943B2 (en) 2010-12-07
MA29481B1 (fr) 2008-05-02
UY29593A1 (es) 2007-01-31
EP1896485B1 (de) 2010-05-19
PL1896485T3 (pl) 2010-10-29
ZA200709501B (en) 2008-10-29
DK1896485T3 (da) 2010-09-06
US20080167339A1 (en) 2008-07-10
AU2006257022A1 (en) 2006-12-14
JP2008542410A (ja) 2008-11-27
NO20080133L (no) 2008-03-05
CY1110213T1 (el) 2012-05-23

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