SI1042319T1 - Dihydrobenzofurans - Google Patents

Dihydrobenzofurans

Info

Publication number
SI1042319T1
SI1042319T1 SI9830628T SI9830628T SI1042319T1 SI 1042319 T1 SI1042319 T1 SI 1042319T1 SI 9830628 T SI9830628 T SI 9830628T SI 9830628 T SI9830628 T SI 9830628T SI 1042319 T1 SI1042319 T1 SI 1042319T1
Authority
SI
Slovenia
Prior art keywords
dihydrobenzofurans
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
SI9830628T
Other languages
English (en)
Slovenian (sl)
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich H�FNER
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-R�diger ULRICH
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of SI1042319T1 publication Critical patent/SI1042319T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9830628T 1997-12-15 1998-12-10 Dihydrobenzofurans SI1042319T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans
EP98966288A EP1042319B1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
SI1042319T1 true SI1042319T1 (en) 2004-08-31

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830628T SI1042319T1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Country Status (17)

Country Link
US (1) US6380196B1 (et)
EP (1) EP1042319B1 (et)
JP (1) JP2002508368A (et)
AT (1) ATE258930T1 (et)
AU (1) AU753576B2 (et)
CA (1) CA2314111A1 (et)
CZ (1) CZ299304B6 (et)
DE (1) DE69821530T2 (et)
DK (1) DK1042319T3 (et)
EE (1) EE04312B1 (et)
ES (1) ES2216349T3 (et)
HU (1) HU225114B1 (et)
IL (1) IL136359A (et)
PL (1) PL191236B1 (et)
PT (1) PT1042319E (et)
SI (1) SI1042319T1 (et)
WO (1) WO1999031090A1 (et)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1212089E (pt) 1999-08-21 2006-08-31 Altana Pharma Ag Combinacao sinergica de roflumilast e salmeterol
WO2001019818A1 (en) * 1999-09-14 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
IL148807A0 (en) 1999-10-25 2002-09-12 Byk Gulden Lomberg Chem Fab Tetrahydrothiopyran derivatives and pharmaceutical compositions containing the same
ATE374189T1 (de) 1999-10-25 2007-10-15 Nycomed Gmbh Phthalazinon-derivate als pde 4 hemmer
PL358057A1 (en) 2000-06-05 2004-08-09 Altana Pharma Ag Compounds effective as beta-2-adrenoreceptor agonists as well as pde4-inhibitors
EE05386B1 (et) * 2001-02-15 2011-02-15 ALTANA�Pharma�AG Ftalasinoon-piperidinoderivaadid,ÁnendeÁkasutamineÁjaÁravim
EP1385838A1 (en) 2001-04-25 2004-02-04 ALTANA Pharma AG Piperazino-derivatives and their use as pde4 inhibitor
CA2445233A1 (en) 2001-04-25 2002-10-31 Altana Pharma Ag Phthalazinones derivatives useful as pde4/7 inhibitors
CN1646118A (zh) * 2002-03-29 2005-07-27 中外制药株式会社 预防或治疗呼吸系统疾病的药物组合物
US20060167001A1 (en) * 2002-08-10 2006-07-27 Sterk Jan G Pyridazinone-derivatives as pde4 inhibitors
WO2004018457A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Pyrrolidinedione substituted piperidine-phthalazones as pde4 inhibitors
WO2004018449A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
WO2004018450A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-n-oxide-derivatives
JP4778449B2 (ja) * 2004-02-04 2011-09-21 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｄｅ４インヒビターとしての２−（ピペリジン−４−イル）−４，５−ジヒドロ−２ｈ−ピリダジン−３−オン誘導体
EP1716123A1 (en) * 2004-02-04 2006-11-02 Altana Pharma AG Pyridazinone derivatives and their use as pde4 inhibitors
JP4890439B2 (ja) * 2005-03-07 2012-03-07 杏林製薬株式会社 ピラゾロピリジン−４−イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするｐｄｅ阻害剤
WO2007058392A1 (ja) * 2005-11-21 2007-05-24 Japan Tobacco Inc. ヘテロ環化合物およびその医薬用途
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
JPH04504576A (ja) * 1989-04-17 1992-08-13 ビイク　グルデン　ロンベルク―ヒェーミッシェ　ファブリーク　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 新規アリールピリダジン、その製造、使用およびこれを含有する医薬品
JP3120857B2 (ja) 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
ATE168101T1 (de) * 1990-10-16 1998-07-15 Byk Gulden Lomberg Chem Fab Arylpyridazinone
US5449676A (en) * 1991-04-26 1995-09-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyridazines
JPH06508842A (ja) * 1991-07-05 1994-10-06 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング 置換ピリダジンの皮膚病に対する使用
DK0612321T3 (da) 1991-10-09 1999-12-13 Syntex Inc Pyridopyridazinon- og pyridazinthionforbindelser med PDE IV inhiberende aktivitet
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
DE69332762T2 (de) 1992-12-02 2003-08-14 Pfizer Inc., New York Cathecoldiether als selektive pde iv hemmungsmittel
US5476834A (en) * 1993-03-17 1995-12-19 Sumitomo Chemical Company, Limited Dihydrobenzofuran derivatives, their production and use
MX9700557A (es) * 1994-07-22 1997-12-31 Byk Gulden Lomberg Chem Fab Dihidrobenzofuranos.
HU219864B (hu) * 1994-08-09 2001-08-28 Eisai Co., Ltd. cGMP-PDE inhibitor kondenzált piridazinszármazékok és alkalmazásuk
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
PT1042319E (pt) 2004-06-30
US6380196B1 (en) 2002-04-30
EE200000335A (et) 2001-10-15
CZ20002218A3 (cs) 2000-11-15
CA2314111A1 (en) 1999-06-24
AU753576B2 (en) 2002-10-24
EP1042319A1 (en) 2000-10-11
DE69821530D1 (de) 2004-03-11
PL191236B1 (pl) 2006-04-28
EE04312B1 (et) 2004-06-15
DE69821530T2 (de) 2004-12-23
AU2270199A (en) 1999-07-05
ATE258930T1 (de) 2004-02-15
PL341239A1 (en) 2001-03-26
HUP0004561A3 (en) 2002-04-29
HUP0004561A2 (hu) 2002-03-28
IL136359A0 (en) 2001-06-14
WO1999031090A1 (en) 1999-06-24
DK1042319T3 (da) 2004-06-01
JP2002508368A (ja) 2002-03-19
EP1042319B1 (en) 2004-02-04
ES2216349T3 (es) 2004-10-16
IL136359A (en) 2003-03-12
HU225114B1 (en) 2006-06-28
CZ299304B6 (cs) 2008-06-11

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