DK1042319T3 - Dihydrobenzofuraner - Google Patents

Dihydrobenzofuraner

Info

Publication number
DK1042319T3
DK1042319T3 DK98966288T DK98966288T DK1042319T3 DK 1042319 T3 DK1042319 T3 DK 1042319T3 DK 98966288 T DK98966288 T DK 98966288T DK 98966288 T DK98966288 T DK 98966288T DK 1042319 T3 DK1042319 T3 DK 1042319T3
Authority
DK
Denmark
Prior art keywords
dihydrobenzofuranes
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
DK98966288T
Other languages
Danish (da)
English (en)
Inventor
Hildegard Boss
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-Ruediger Ulrich
Ulrich Thibaut
Armin Hatzelmann
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1042319T3 publication Critical patent/DK1042319T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98966288T 1997-12-15 1998-12-10 Dihydrobenzofuraner DK1042319T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
DK1042319T3 true DK1042319T3 (da) 2004-06-01

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98966288T DK1042319T3 (da) 1997-12-15 1998-12-10 Dihydrobenzofuraner

Country Status (17)

Country Link
US (1) US6380196B1 (et)
EP (1) EP1042319B1 (et)
JP (1) JP2002508368A (et)
AT (1) ATE258930T1 (et)
AU (1) AU753576B2 (et)
CA (1) CA2314111A1 (et)
CZ (1) CZ299304B6 (et)
DE (1) DE69821530T2 (et)
DK (1) DK1042319T3 (et)
EE (1) EE04312B1 (et)
ES (1) ES2216349T3 (et)
HU (1) HU225114B1 (et)
IL (1) IL136359A (et)
PL (1) PL191236B1 (et)
PT (1) PT1042319E (et)
SI (1) SI1042319T1 (et)
WO (1) WO1999031090A1 (et)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU777012B2 (en) 1999-08-21 2004-09-30 Takeda Gmbh Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist
AU7654200A (en) * 1999-09-14 2001-04-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
CA2388121A1 (en) 1999-10-25 2001-05-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pde 4 inhibitors
PL354979A1 (en) * 1999-10-25 2004-03-22 Altana Pharma Ag Tetrahydrothiopy ranphthalazinone derivatives as pde4 inhibitors
SK17052002A3 (sk) * 2000-06-05 2003-12-02 Altana Pharma Ag Pyridazinónové zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie
NZ527424A (en) * 2001-02-15 2005-02-25 Altana Pharma Ag Phthalayinone-piperidino-derivatives as PDE4 inhibitors
NZ529363A (en) * 2001-04-25 2005-08-26 Altana Pharma Ag Novel Piperazino-derivatives
CN1503792A (zh) 2001-04-25 2004-06-09 ��̹��ҽҩ��˾ 新的酞嗪酮
AU2003219559A1 (en) * 2002-03-29 2003-10-13 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for preventing or treating respiratory disease
CA2494650A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Pyridazinone-derivatives as pde4 inhibitors
EP1542987A1 (en) * 2002-08-10 2005-06-22 ALTANA Pharma AG Piperidine-n-oxide-derivatives
AU2003260376A1 (en) * 2002-08-10 2004-03-11 Altana Pharma Ag Piperidine-pyridazones and phthalazones as pde4 inhibitors
AU2003255376A1 (en) * 2002-08-10 2004-03-11 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
WO2005075456A1 (en) * 2004-02-04 2005-08-18 Altana Pharma Ag 2-(piperidin-4-yl) -4, 5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
EP1716123A1 (en) * 2004-02-04 2006-11-02 Altana Pharma AG Pyridazinone derivatives and their use as pde4 inhibitors
JP4890439B2 (ja) * 2005-03-07 2012-03-07 杏林製薬株式会社 ピラゾロピリジン−４−イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするｐｄｅ阻害剤
AR057986A1 (es) * 2005-11-21 2008-01-09 Japan Tobacco Inc Compuesto heterociclico y su uso farmaceutico
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
ES2075202T3 (es) * 1989-04-17 1995-10-01 Byk Gulden Lomberg Chem Fab Nuevas arilpiridazinas, su preparacion, su utilizacion, y medicamentos que las contienen.
WO1991012251A1 (en) 1990-02-19 1991-08-22 Chugai Seiyaku Kabushiki Kaisha Novel fused heterocyclic compound and antiasthmatic agent prepared therefrom
DE59109027D1 (en) * 1990-10-16 1998-08-13 Byk Gulden Lomberg Chem Fab Arylpyridazinone
EP0581805A1 (de) * 1991-04-26 1994-02-09 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
JPH06508842A (ja) * 1991-07-05 1994-10-06 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング 置換ピリダジンの皮膚病に対する使用
ES2135416T3 (es) * 1991-10-09 1999-11-01 Syntex Inc Compuestos de piridopiridazinonas y piridazintionas con actividad inhibidora de la pde iv.
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
AU673569B2 (en) * 1992-12-02 1996-11-14 Pfizer Inc. Catechol diethers as selective PDE-IV inhibitors
US5411935A (en) * 1993-03-17 1995-05-02 Sumitomo Chemical Co., Ltd. Dihydrobenzofuran derivatives, their production and use
HU221504B (en) 1994-07-22 2002-10-28 Byk Gulden Lomberg Chem Fab Dihydrobenzofuranes
NZ290952A (en) * 1994-08-09 1998-05-27 Eisai Co Ltd Phthalazine derivatives optionally substituted in position-1 by (generally benzyl) amino groups
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
PL341239A1 (en) 2001-03-26
JP2002508368A (ja) 2002-03-19
CA2314111A1 (en) 1999-06-24
IL136359A0 (en) 2001-06-14
EP1042319B1 (en) 2004-02-04
CZ20002218A3 (cs) 2000-11-15
IL136359A (en) 2003-03-12
EE04312B1 (et) 2004-06-15
DE69821530D1 (de) 2004-03-11
AU2270199A (en) 1999-07-05
EP1042319A1 (en) 2000-10-11
ATE258930T1 (de) 2004-02-15
AU753576B2 (en) 2002-10-24
DE69821530T2 (de) 2004-12-23
HUP0004561A3 (en) 2002-04-29
SI1042319T1 (en) 2004-08-31
PL191236B1 (pl) 2006-04-28
HU225114B1 (en) 2006-06-28
ES2216349T3 (es) 2004-10-16
EE200000335A (et) 2001-10-15
HUP0004561A2 (hu) 2002-03-28
WO1999031090A1 (en) 1999-06-24
PT1042319E (pt) 2004-06-30
US6380196B1 (en) 2002-04-30
CZ299304B6 (cs) 2008-06-11

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