SI0863868T1 - Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives - Google Patents

Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives

Info

Publication number
SI0863868T1
SI0863868T1 SI9630254T SI9630254T SI0863868T1 SI 0863868 T1 SI0863868 T1 SI 0863868T1 SI 9630254 T SI9630254 T SI 9630254T SI 9630254 T SI9630254 T SI 9630254T SI 0863868 T1 SI0863868 T1 SI 0863868T1
Authority
SI
Slovenia
Prior art keywords
derivatives
preparation
cyanocyclobutane
aryl
dimethyl sulphoxide
Prior art date
Application number
SI9630254T
Other languages
English (en)
Inventor
Stephen John Barker
Sharon Michelle Clark
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of SI0863868T1 publication Critical patent/SI0863868T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Catalysts (AREA)
SI9630254T 1995-12-02 1996-11-28 Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives SI0863868T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9524681.5A GB9524681D0 (en) 1995-12-02 1995-12-02 Chemical process
PCT/EP1996/005246 WO1997020810A1 (en) 1995-12-02 1996-11-28 Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives
EP96941602A EP0863868B1 (en) 1995-12-02 1996-11-28 Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives

Publications (1)

Publication Number Publication Date
SI0863868T1 true SI0863868T1 (en) 2001-06-30

Family

ID=10784817

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630254T SI0863868T1 (en) 1995-12-02 1996-11-28 Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives

Country Status (28)

Country Link
US (1) US6545173B1 (ru)
EP (1) EP0863868B1 (ru)
JP (1) JP2000501402A (ru)
KR (1) KR19990071838A (ru)
CN (1) CN1075057C (ru)
AT (1) ATE199247T1 (ru)
AU (1) AU717603B2 (ru)
BG (1) BG63498B1 (ru)
BR (1) BR9611683A (ru)
CA (1) CA2235043A1 (ru)
CZ (1) CZ164798A3 (ru)
DE (1) DE69611835T2 (ru)
DK (1) DK0863868T3 (ru)
ES (1) ES2154848T3 (ru)
GB (1) GB9524681D0 (ru)
GR (1) GR3035572T3 (ru)
HU (1) HUP9903481A3 (ru)
IL (1) IL124341A (ru)
MX (1) MX9804022A (ru)
NO (1) NO309265B1 (ru)
NZ (1) NZ323896A (ru)
PL (1) PL185047B1 (ru)
PT (1) PT863868E (ru)
RU (1) RU2179168C2 (ru)
SI (1) SI0863868T1 (ru)
SK (1) SK282470B6 (ru)
TR (1) TR199800987T2 (ru)
WO (1) WO1997020810A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
US6504044B2 (en) 2001-02-28 2003-01-07 Council Of Scientific And Industrial Research Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol
DE60110364T2 (de) * 2001-02-28 2006-02-16 Council Of Scientific And Industrial Research Verfahren zur Herstellung von 1-(Cyan(aryl)methyl)cyclohexanol
WO2002083631A1 (en) 2001-04-13 2002-10-24 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
AT503354B1 (de) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen
CZ300903B6 (cs) * 2008-06-09 2009-09-09 Lucební závody Draslovka a. s. Kolín Zpusob výroby cykloalkankarbonitrilu

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526656A (en) 1967-05-25 1970-09-01 Parke Davis & Co (1-arylcyclobutyl)carbonyl carbamic acid derivatives
US4220591A (en) 1975-11-26 1980-09-02 Commonwealth Scientific And Industrial Research Organization Insecticidal esters
AU4244478A (en) 1977-12-19 1979-06-28 Commw Scient Ind Res Org Cyclobutane carboxylic acids and esters and insecticides
ZA821577B (en) * 1981-04-06 1983-03-30 Boots Co Plc Therapeutic agents
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
ZA925185B (en) 1991-07-18 1993-04-29 Hoffmann La Roche Dithianes.
GB9127306D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
GB9309749D0 (en) 1993-05-12 1993-06-23 Boots Co Plc Therapeutic agents
EP0707570B1 (en) 1993-06-22 1998-05-06 Knoll AG Isoquinoline derivatives as therapeutic agents

Also Published As

Publication number Publication date
AU717603B2 (en) 2000-03-30
ATE199247T1 (de) 2001-03-15
NZ323896A (en) 2000-01-28
BR9611683A (pt) 1999-03-02
US6545173B1 (en) 2003-04-08
DK0863868T3 (da) 2001-03-19
TR199800987T2 (xx) 1998-09-21
BG63498B1 (bg) 2002-03-29
HUP9903481A3 (en) 2001-11-28
SK62698A3 (en) 1999-02-11
SK282470B6 (sk) 2002-02-05
WO1997020810A1 (en) 1997-06-12
RU2179168C2 (ru) 2002-02-10
CN1075057C (zh) 2001-11-21
BG102473A (en) 1999-05-31
CA2235043A1 (en) 1997-06-12
KR19990071838A (ko) 1999-09-27
GR3035572T3 (en) 2001-06-29
NO309265B1 (no) 2001-01-08
NO982474D0 (no) 1998-05-29
CN1203585A (zh) 1998-12-30
PT863868E (pt) 2001-06-29
CZ164798A3 (cs) 1998-09-16
EP0863868A1 (en) 1998-09-16
ES2154848T3 (es) 2001-04-16
EP0863868B1 (en) 2001-02-21
PL185047B1 (pl) 2003-02-28
MX9804022A (es) 1998-09-30
HUP9903481A1 (hu) 2001-01-29
WO1997020810A8 (en) 2000-10-05
DE69611835D1 (de) 2001-03-29
GB9524681D0 (en) 1996-01-31
DE69611835T2 (de) 2001-06-07
NO982474L (no) 1998-05-29
PL326926A1 (en) 1998-11-09
IL124341A (en) 2001-09-13
JP2000501402A (ja) 2000-02-08
AU1093997A (en) 1997-06-27
IL124341A0 (en) 1998-12-06

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