ES2154848T3 - Procedimiento para la preparacion de derivados de 1-aril-1-cianociclobutano. - Google Patents

Procedimiento para la preparacion de derivados de 1-aril-1-cianociclobutano.

Info

Publication number
ES2154848T3
ES2154848T3 ES96941602T ES96941602T ES2154848T3 ES 2154848 T3 ES2154848 T3 ES 2154848T3 ES 96941602 T ES96941602 T ES 96941602T ES 96941602 T ES96941602 T ES 96941602T ES 2154848 T3 ES2154848 T3 ES 2154848T3
Authority
ES
Spain
Prior art keywords
derivatives
preparation
cianociclobutan
aril
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96941602T
Other languages
English (en)
Inventor
Stephen John Barker
Sharon Michelle Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Application granted granted Critical
Publication of ES2154848T3 publication Critical patent/ES2154848T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Catalysts (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE DERIVADOS DE ARILCICLOBUTILNITRILO QUE IMPLICA LA REACCION DE UNA SOLUCION DE UN 1,3 - DIHALOPROPANO Y UN DERIVADO CIANOBENCILO EN UN SOLVENTE SUSTANCIALMENTE LIBRE DE DIMETILSULFOXIDO CON UNA SUSPENSION DE UNA BASE EN UN SOLVENTE SUSTANCIALMENTE LIBRE DE DIMETILSULFOXIDO A UNA TEMPERATURA DE AL MENOS 35 (GRADOS) C.
ES96941602T 1995-12-02 1996-11-28 Procedimiento para la preparacion de derivados de 1-aril-1-cianociclobutano. Expired - Lifetime ES2154848T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9524681.5A GB9524681D0 (en) 1995-12-02 1995-12-02 Chemical process

Publications (1)

Publication Number Publication Date
ES2154848T3 true ES2154848T3 (es) 2001-04-16

Family

ID=10784817

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96941602T Expired - Lifetime ES2154848T3 (es) 1995-12-02 1996-11-28 Procedimiento para la preparacion de derivados de 1-aril-1-cianociclobutano.

Country Status (28)

Country Link
US (1) US6545173B1 (es)
EP (1) EP0863868B1 (es)
JP (1) JP2000501402A (es)
KR (1) KR19990071838A (es)
CN (1) CN1075057C (es)
AT (1) ATE199247T1 (es)
AU (1) AU717603B2 (es)
BG (1) BG63498B1 (es)
BR (1) BR9611683A (es)
CA (1) CA2235043A1 (es)
CZ (1) CZ164798A3 (es)
DE (1) DE69611835T2 (es)
DK (1) DK0863868T3 (es)
ES (1) ES2154848T3 (es)
GB (1) GB9524681D0 (es)
GR (1) GR3035572T3 (es)
HU (1) HUP9903481A3 (es)
IL (1) IL124341A (es)
MX (1) MX9804022A (es)
NO (1) NO309265B1 (es)
NZ (1) NZ323896A (es)
PL (1) PL185047B1 (es)
PT (1) PT863868E (es)
RU (1) RU2179168C2 (es)
SI (1) SI0863868T1 (es)
SK (1) SK282470B6 (es)
TR (1) TR199800987T2 (es)
WO (1) WO1997020810A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
US6504044B2 (en) 2001-02-28 2003-01-07 Council Of Scientific And Industrial Research Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol
DE60110364T2 (de) * 2001-02-28 2006-02-16 Council Of Scientific And Industrial Research Verfahren zur Herstellung von 1-(Cyan(aryl)methyl)cyclohexanol
WO2002083631A1 (en) 2001-04-13 2002-10-24 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
AT503354B1 (de) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen
CZ300903B6 (cs) * 2008-06-09 2009-09-09 Lucební závody Draslovka a. s. Kolín Zpusob výroby cykloalkankarbonitrilu

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526656A (en) 1967-05-25 1970-09-01 Parke Davis & Co (1-arylcyclobutyl)carbonyl carbamic acid derivatives
US4220591A (en) 1975-11-26 1980-09-02 Commonwealth Scientific And Industrial Research Organization Insecticidal esters
AU4244478A (en) 1977-12-19 1979-06-28 Commw Scient Ind Res Org Cyclobutane carboxylic acids and esters and insecticides
ZA821577B (en) * 1981-04-06 1983-03-30 Boots Co Plc Therapeutic agents
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
ZA925185B (en) 1991-07-18 1993-04-29 Hoffmann La Roche Dithianes.
GB9127306D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
GB9309749D0 (en) 1993-05-12 1993-06-23 Boots Co Plc Therapeutic agents
EP0707570B1 (en) 1993-06-22 1998-05-06 Knoll AG Isoquinoline derivatives as therapeutic agents

Also Published As

Publication number Publication date
AU717603B2 (en) 2000-03-30
ATE199247T1 (de) 2001-03-15
NZ323896A (en) 2000-01-28
BR9611683A (pt) 1999-03-02
US6545173B1 (en) 2003-04-08
DK0863868T3 (da) 2001-03-19
TR199800987T2 (xx) 1998-09-21
BG63498B1 (bg) 2002-03-29
HUP9903481A3 (en) 2001-11-28
SK62698A3 (en) 1999-02-11
SK282470B6 (sk) 2002-02-05
WO1997020810A1 (en) 1997-06-12
RU2179168C2 (ru) 2002-02-10
SI0863868T1 (en) 2001-06-30
CN1075057C (zh) 2001-11-21
BG102473A (en) 1999-05-31
CA2235043A1 (en) 1997-06-12
KR19990071838A (ko) 1999-09-27
GR3035572T3 (en) 2001-06-29
NO309265B1 (no) 2001-01-08
NO982474D0 (no) 1998-05-29
CN1203585A (zh) 1998-12-30
PT863868E (pt) 2001-06-29
CZ164798A3 (cs) 1998-09-16
EP0863868A1 (en) 1998-09-16
EP0863868B1 (en) 2001-02-21
PL185047B1 (pl) 2003-02-28
MX9804022A (es) 1998-09-30
HUP9903481A1 (hu) 2001-01-29
WO1997020810A8 (en) 2000-10-05
DE69611835D1 (de) 2001-03-29
GB9524681D0 (en) 1996-01-31
DE69611835T2 (de) 2001-06-07
NO982474L (no) 1998-05-29
PL326926A1 (en) 1998-11-09
IL124341A (en) 2001-09-13
JP2000501402A (ja) 2000-02-08
AU1093997A (en) 1997-06-27
IL124341A0 (en) 1998-12-06

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