ES2052797T3 - Procedimiento para la obtencion de heteroaromatos de cinco miembros que contienen nitrogeno. - Google Patents

Procedimiento para la obtencion de heteroaromatos de cinco miembros que contienen nitrogeno.

Info

Publication number
ES2052797T3
ES2052797T3 ES89105365T ES89105365T ES2052797T3 ES 2052797 T3 ES2052797 T3 ES 2052797T3 ES 89105365 T ES89105365 T ES 89105365T ES 89105365 T ES89105365 T ES 89105365T ES 2052797 T3 ES2052797 T3 ES 2052797T3
Authority
ES
Spain
Prior art keywords
heteroaromates
procedure
obtaining
pct
containing nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89105365T
Other languages
English (en)
Inventor
Richard Dr Kirchlechner
Michael Dr Casutt
Arno Prof Dr Basedow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of ES2052797T3 publication Critical patent/ES2052797T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

COMPUESTOS DE LA FORMULA I: DONDE A Y X EXP1 TIENEN LOS SIGNIFICADOS DADOS EN LA PARTE Y DE LA PATENTE, SE PUEDEN OBTENER DE UNA FORMA FACIL EN UN PROCEDIMIENTO Y CON UN ALTO RENDIMIENTO.
ES89105365T 1988-04-07 1989-03-25 Procedimiento para la obtencion de heteroaromatos de cinco miembros que contienen nitrogeno. Expired - Lifetime ES2052797T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3811621A DE3811621A1 (de) 1988-04-07 1988-04-07 Verfahren zur herstellung von 1h-imidazol-5-carbon-saeureestern oder -nitrilen und von pyrrol-3,4-carbonsaeureestern oder -nitrilen sowie verwendung der hergestellten verbindungen zur synthese von pilocarpin

Publications (1)

Publication Number Publication Date
ES2052797T3 true ES2052797T3 (es) 1994-07-16

Family

ID=6351532

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89105365T Expired - Lifetime ES2052797T3 (es) 1988-04-07 1989-03-25 Procedimiento para la obtencion de heteroaromatos de cinco miembros que contienen nitrogeno.

Country Status (15)

Country Link
US (1) US5075452A (es)
EP (2) EP0336250B1 (es)
JP (2) JP2805230B2 (es)
KR (1) KR0122131B1 (es)
CN (1) CN1022920C (es)
AT (1) ATE80388T1 (es)
AU (1) AU616962B2 (es)
CA (1) CA1338787C (es)
DE (2) DE3811621A1 (es)
ES (1) ES2052797T3 (es)
HU (1) HU202214B (es)
IE (1) IE63676B1 (es)
IL (1) IL89860A0 (es)
WO (1) WO1989009768A1 (es)
ZA (1) ZA892516B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4033612A1 (de) * 1990-10-23 1992-04-30 Merck Patent Gmbh Verfahren zur herstellung von racemischen pilosinin-derivaten
JPH0641067A (ja) * 1992-04-20 1994-02-15 Kitasato Inst:The 新規カルパイン阻害物質ｋｐ−１２４１及びその製造法
GB9220068D0 (en) * 1992-09-23 1992-11-04 Smithkline Beecham Corp Process
US5565577A (en) * 1992-09-23 1996-10-15 Smithkline Beecham Corporation Process for preparing 1-alkyaryl-2-alkyl-5-formylimidazole
PT964855E (pt) * 1997-01-13 2002-04-29 Lonza Ag Processo para a fabricacao de derivados substituidos de pirimidina
CN1086189C (zh) * 1997-06-12 2002-06-12 食品机械和化工公司 超细微晶纤维素组合物及其制备方法
CN101397274B (zh) * 2008-10-22 2012-06-27 江苏先声药物研究有限公司 一种天然咪唑甲酸衍生物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1184709A (fr) * 1957-09-21 1959-07-24 Cfmc Nouveaux dérivés imidazoliques, utilisables comme agents de protection contre les rayons ultra-violets et leurs procédés de fabrication
GB8516573D0 (en) * 1985-07-01 1985-08-07 Janssen Pharmaceuticaa Nv Controlling weeds
JPS61178968A (ja) * 1985-12-13 1986-08-11 Nippon Carbide Ind Co Ltd １−置換イミダゾ−ル−５−カルボキサミド誘導体の製法
JP2562872B2 (ja) * 1986-01-25 1996-12-11 四国化成工業 株式会社 シアノ−イミダゾ−ル化合物の合成法
DE3729852A1 (de) * 1987-09-05 1989-03-23 Basf Ag Verfahren zur herstellung von 1-alkylimidazol-5-carbonsaeuren sowie deren estern, amiden und nitrilen

Also Published As

Publication number Publication date
EP0336250A1 (de) 1989-10-11
ZA892516B (en) 1989-12-27
US5075452A (en) 1991-12-24
AU616962B2 (en) 1991-11-14
JPH02504518A (ja) 1990-12-20
WO1989009768A1 (en) 1989-10-19
KR0122131B1 (ko) 1997-11-13
ATE80388T1 (de) 1992-09-15
CN1022920C (zh) 1993-12-01
CA1338787C (en) 1996-12-10
KR900700461A (ko) 1990-08-13
HU202214B (en) 1991-02-28
CN1037896A (zh) 1989-12-13
JP3226863B2 (ja) 2001-11-05
DE3811621A1 (de) 1989-10-26
IE891101L (en) 1989-10-07
IL89860A0 (en) 1989-12-15
AU3364289A (en) 1989-11-03
HU892146D0 (en) 1990-02-28
JP2805230B2 (ja) 1998-09-30
EP0362350A1 (de) 1990-04-11
JPH10182637A (ja) 1998-07-07
DE58902228D1 (de) 1992-10-15
IE63676B1 (en) 1995-05-31
HUT51258A (en) 1990-04-28
EP0336250B1 (de) 1992-09-09

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