ES2037116T3 - Procedimiento para la obtencion de bencilaminoarildihidropiridinlactonas. - Google Patents

Procedimiento para la obtencion de bencilaminoarildihidropiridinlactonas.

Info

Publication number
ES2037116T3
ES2037116T3 ES198888102124T ES88102124T ES2037116T3 ES 2037116 T3 ES2037116 T3 ES 2037116T3 ES 198888102124 T ES198888102124 T ES 198888102124T ES 88102124 T ES88102124 T ES 88102124T ES 2037116 T3 ES2037116 T3 ES 2037116T3
Authority
ES
Spain
Prior art keywords
bencilaminoarildihidropiridinlactonas
procedure
obtaining
benzylaminoaryldihydropyridine
lactones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888102124T
Other languages
English (en)
Inventor
Siegfried Dr. Goldmann
Rainer Prof. Dr. Gross
Martin Dr. Bechem
Michael Dr. Kayser
Matthias Dr. Schramm
Siegbert Dr. Hebisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2037116T3 publication Critical patent/ES2037116T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

EL INVENTO CONSISTE EN BENZILAMINOARIL - DIHIPIRIDINLACTON DE LA FORMULA GENERAL (I). PROCEDIMIENTO PARA SU FABRICACION ASI COMO SU UTILIZACION EN MEDICAMENTOS, ESPECIALMENTE EN MEDICA MEDICAMENTOS INFLUYENTES EN LA CIRCULACION.
ES198888102124T 1987-02-26 1988-02-13 Procedimiento para la obtencion de bencilaminoarildihidropiridinlactonas. Expired - Lifetime ES2037116T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873706204 DE3706204A1 (de) 1987-02-26 1987-02-26 Benzylaminoaryl-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ES2037116T3 true ES2037116T3 (es) 1993-06-16

Family

ID=6321825

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888102124T Expired - Lifetime ES2037116T3 (es) 1987-02-26 1988-02-13 Procedimiento para la obtencion de bencilaminoarildihidropiridinlactonas.

Country Status (14)

Country Link
US (1) US4904665A (es)
EP (1) EP0281789B1 (es)
JP (1) JP2647413B2 (es)
KR (1) KR880009967A (es)
AT (1) ATE62688T1 (es)
AU (1) AU600798B2 (es)
CA (1) CA1304375C (es)
DE (2) DE3706204A1 (es)
DK (1) DK98788A (es)
ES (1) ES2037116T3 (es)
GR (1) GR3001809T3 (es)
HU (1) HU198211B (es)
IL (1) IL85508A (es)
ZA (1) ZA881322B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3410645A1 (de) * 1984-03-23 1985-09-26 Bayer Ag, 5090 Leverkusen L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3600596A1 (de) * 1986-01-11 1987-07-16 Bayer Ag 4-aminoaryldihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
KR880009967A (ko) 1988-10-06
ATE62688T1 (de) 1991-05-15
ZA881322B (en) 1988-08-23
HUT47286A (en) 1989-02-28
EP0281789A1 (de) 1988-09-14
DE3862404D1 (de) 1991-05-23
CA1304375C (en) 1992-06-30
AU600798B2 (en) 1990-08-23
AU1239788A (en) 1988-09-01
HU198211B (en) 1989-08-28
IL85508A (en) 1991-11-21
DK98788D0 (da) 1988-02-25
DE3706204A1 (de) 1988-09-08
JP2647413B2 (ja) 1997-08-27
US4904665A (en) 1990-02-27
IL85508A0 (en) 1988-08-31
DK98788A (da) 1988-08-27
GR3001809T3 (en) 1992-11-23
JPS63227589A (ja) 1988-09-21
EP0281789B1 (de) 1991-04-17

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