ES2061532T3 - Derivados sustituidos de acido piridina-2,4-dicarboxilico, procedimientos para su preparacion, utilizacion de los mismos, asi como medicamentos a base de estos compuestos. - Google Patents

Derivados sustituidos de acido piridina-2,4-dicarboxilico, procedimientos para su preparacion, utilizacion de los mismos, asi como medicamentos a base de estos compuestos.

Info

Publication number
ES2061532T3
ES2061532T3 ES88103270T ES88103270T ES2061532T3 ES 2061532 T3 ES2061532 T3 ES 2061532T3 ES 88103270 T ES88103270 T ES 88103270T ES 88103270 T ES88103270 T ES 88103270T ES 2061532 T3 ES2061532 T3 ES 2061532T3
Authority
ES
Spain
Prior art keywords
dicarboxilico
piridina
procedures
compounds
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88103270T
Other languages
English (en)
Inventor
Ekkehard Dr Baader
Martin Dr Bickel
Dietrich Dr Brocks
Volkmar Dr Gunzler
Stephan Dr Henke
Hartmut Dr Hanauske-Abel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2061532T3 publication Critical patent/ES2061532T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Stringed Musical Instruments (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA INVENCION SE REFIERE A DERIVADOS DE ACIDOS PIRIDIN-2,4DICARBOXILICOS SUSTITUIOD DE FORMULA (I) EN LA QUE R1 Y R2 TIENNELOS SIGNIFICADOS QUE SE INDICAN EN LA DESCRIPCION. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA OBTENCION DE ESTOS COMPUESTOS ASI COMO A SU APLICACION COMO MEDICAMENTOS, EN PARTICULAR COMO FIBROSUPRESORES E INMUNOSUPRESORES.
ES88103270T 1987-03-07 1988-03-03 Derivados sustituidos de acido piridina-2,4-dicarboxilico, procedimientos para su preparacion, utilizacion de los mismos, asi como medicamentos a base de estos compuestos. Expired - Lifetime ES2061532T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873707429 DE3707429A1 (de) 1987-03-07 1987-03-07 Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen

Publications (1)

Publication Number Publication Date
ES2061532T3 true ES2061532T3 (es) 1994-12-16

Family

ID=6322561

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88103270T Expired - Lifetime ES2061532T3 (es) 1987-03-07 1988-03-03 Derivados sustituidos de acido piridina-2,4-dicarboxilico, procedimientos para su preparacion, utilizacion de los mismos, asi como medicamentos a base de estos compuestos.

Country Status (14)

Country Link
US (3) US5004748A (es)
EP (1) EP0281943B1 (es)
JP (1) JPS63238059A (es)
KR (1) KR960004860B1 (es)
AT (1) ATE100088T1 (es)
AU (1) AU614074B2 (es)
CA (1) CA1321391C (es)
DE (2) DE3707429A1 (es)
DK (1) DK167873B1 (es)
ES (1) ES2061532T3 (es)
IE (1) IE62536B1 (es)
IL (1) IL85658A (es)
PT (1) PT86904B (es)
ZA (1) ZA881561B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5425289A (en) * 1993-10-21 1995-06-20 Snap-On Incorporated Bung tool
DE4030999A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
DE4233124A1 (de) * 1992-10-02 1994-04-07 Hoechst Ag Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2270123A1 (en) * 1996-10-28 1998-05-07 Department Of The Army, U.S. Government Compounds, compositions and methods for treating antibiotic-resistant infections
WO1999021860A1 (en) * 1997-10-24 1999-05-06 Fibrogen, Inc. Phenanthroline derivatives
FR2987742B1 (fr) 2012-03-09 2014-09-26 Oreal Procede de traitement pour la protection et la reparation des fibres keratiniques mettant en œuvre des polysaccharides oxydes
FR3010312B1 (fr) 2013-09-12 2015-09-11 Oreal Procede de traitement des fibres keratiniques avec un polysaccharide et un compose d'acide pyridine dicarboxylique
FR3010308B1 (fr) * 2013-09-12 2016-11-25 Oreal Procede de traitement des fibres keratiniques avec un compose d'acide pyridine dicarboxylique
FR3010309B1 (fr) 2013-09-12 2017-03-10 Oreal Procede de traitement des fibres keratiniques avec un polysaccharide et un compose de sphingosine
CN112358442B (zh) * 2020-11-20 2022-03-04 内蒙古佳瑞米精细化工有限公司 一种2-氟-5-甲酰氯吡啶的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482437A (en) * 1984-04-05 1984-11-13 Reilly Tar & Chemical Corp. Electrochemical reductions of cyanopyridine bases
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3615293A1 (de) * 1986-05-06 1987-11-12 Bayer Ag Verwendung von heteroarylethylaminen zur leistungsfoerderung bei tieren, heteroarylethylamine und verfahren zu ihrer herstellung
DE3703963A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
ATE113036T1 (de) * 1988-08-04 1994-11-15 Hoechst Ag Verbessertes verfahren zur herstellung von n,n- bis(alkoxyalkyl)-pyridin -2,4- dicarbonsäurediamiden.
DE3924093A1 (de) * 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3928144A1 (de) * 1989-08-25 1991-02-28 Hoechst Ag Zyklische pyridin-2,4- und -2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3938805A1 (de) * 1989-11-23 1991-05-29 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung

Also Published As

Publication number Publication date
US5356909A (en) 1994-10-18
AU614074B2 (en) 1991-08-22
JPS63238059A (ja) 1988-10-04
EP0281943A3 (en) 1989-06-14
ATE100088T1 (de) 1994-01-15
IL85658A (en) 1992-08-18
DK167873B1 (da) 1993-12-27
US5004748A (en) 1991-04-02
DK119188A (da) 1988-09-08
EP0281943B1 (de) 1994-01-12
DE3886963D1 (de) 1994-02-24
KR880011104A (ko) 1988-10-26
IE62536B1 (en) 1995-02-08
AU1264488A (en) 1988-09-08
KR960004860B1 (en) 1996-04-16
CA1321391C (en) 1993-08-17
DE3707429A1 (de) 1988-09-15
DK119188D0 (da) 1988-03-04
IE880628L (en) 1988-09-07
EP0281943A2 (de) 1988-09-14
PT86904B (pt) 1992-05-29
ZA881561B (en) 1988-08-31
US5143926A (en) 1992-09-01
PT86904A (pt) 1988-04-01

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