SG166771A1 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SG166771A1
SG166771A1 SG201007027-4A SG2010070274A SG166771A1 SG 166771 A1 SG166771 A1 SG 166771A1 SG 2010070274 A SG2010070274 A SG 2010070274A SG 166771 A1 SG166771 A1 SG 166771A1
Authority
SG
Singapore
Prior art keywords
novel compounds
csbp
trisubstituted
pyrido
pyrimidin
Prior art date
Application number
SG201007027-4A
Other languages
English (en)
Inventor
James Francis Callahan
Jeffrey C Boehm
Anthony William James Cooper
Stefano Livia
Neysa Nevins
Zehong Wan
Beth A Norton
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SG166771A1 publication Critical patent/SG166771A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
SG201007027-4A 2005-03-25 2006-03-24 Novel compounds SG166771A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66531505P 2005-03-25 2005-03-25

Publications (1)

Publication Number Publication Date
SG166771A1 true SG166771A1 (en) 2010-12-29

Family

ID=37053943

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201007027-4A SG166771A1 (en) 2005-03-25 2006-03-24 Novel compounds

Country Status (25)

Country Link
US (3) US7678801B2 (de)
EP (3) EP1868611B1 (de)
JP (1) JP5037487B2 (de)
KR (1) KR101235497B1 (de)
CN (4) CN102746301A (de)
AR (1) AR053346A1 (de)
AU (1) AU2006229993B2 (de)
BR (1) BRPI0609437A2 (de)
CA (1) CA2602553C (de)
EA (1) EA012875B1 (de)
ES (2) ES2398246T3 (de)
HK (1) HK1111422A1 (de)
IL (1) IL185870A (de)
MA (1) MA29341B1 (de)
MX (1) MX2007011856A (de)
MY (2) MY145281A (de)
NO (1) NO20075275L (de)
NZ (1) NZ561237A (de)
PE (2) PE20061351A1 (de)
SG (1) SG166771A1 (de)
TW (1) TWI389690B (de)
UA (1) UA95444C2 (de)
UY (1) UY29440A1 (de)
WO (1) WO2006104915A2 (de)
ZA (1) ZA200707564B (de)

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WO2007147103A2 (en) * 2006-06-16 2007-12-21 Glaxo Group Limited Novel compounds
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WO2012158197A2 (en) * 2010-11-11 2012-11-22 Lyndor Biosciences L.L.C. Compounds useful as akt/pkb modulators and uses thereof
JP6035334B2 (ja) * 2011-08-25 2016-11-30 セント ジュード チルドレンズ リサーチ ホスピタル 抗マラリア療法のための置換２−アルキル−１−オキソ−ｎ−フェニル−３−ヘテロアリール−１，２，３，４−テトラヒドロイソキノリン−４−カルボキサミド
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BRPI0609437A2 (pt) 2010-04-06
US20060235029A1 (en) 2006-10-19
CN102746301A (zh) 2012-10-24
EP1868611A4 (de) 2009-05-27
EA200702071A1 (ru) 2008-02-28
CN102746299A (zh) 2012-10-24
CN101258148A (zh) 2008-09-03
WO2006104915A3 (en) 2007-11-22
US20090156597A1 (en) 2009-06-18
IL185870A0 (en) 2008-01-06
CN102746300A (zh) 2012-10-24
IL185870A (en) 2013-06-27
HK1111422A1 (de) 2008-08-08
KR101235497B1 (ko) 2013-02-20
PE20061351A1 (es) 2007-01-14
JP5037487B2 (ja) 2012-09-26
US8207176B2 (en) 2012-06-26
AR053346A1 (es) 2007-05-02
PE20100737A1 (es) 2010-11-27
EP1868611A2 (de) 2007-12-26
UY29440A1 (es) 2006-10-02
AU2006229993A1 (en) 2006-10-05
EA012875B1 (ru) 2009-12-30
NZ561237A (en) 2011-02-25
ES2398246T3 (es) 2013-03-14
WO2006104915A9 (en) 2008-01-03
EP2436686A1 (de) 2012-04-04
MY145281A (en) 2012-01-13
MX2007011856A (es) 2007-10-10
NO20075275L (no) 2007-12-27
ES2426251T3 (es) 2013-10-22
UA95444C2 (ru) 2011-08-10
US7678801B2 (en) 2010-03-16
US8354416B2 (en) 2013-01-15
MY145343A (en) 2012-01-31
TWI389690B (zh) 2013-03-21
KR20070113255A (ko) 2007-11-28
EP1868611B1 (de) 2012-11-14
EP2447266B1 (de) 2013-06-12
ZA200707564B (en) 2008-10-29
US20090069318A1 (en) 2009-03-12
EP2447266A1 (de) 2012-05-02
CA2602553A1 (en) 2006-10-05
JP2008534513A (ja) 2008-08-28
AU2006229993B2 (en) 2011-05-19

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