SG131114A1 - 2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators - Google Patents

2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators

Info

Publication number
SG131114A1
SG131114A1 SG200701706-4A SG2007017064A SG131114A1 SG 131114 A1 SG131114 A1 SG 131114A1 SG 2007017064 A SG2007017064 A SG 2007017064A SG 131114 A1 SG131114 A1 SG 131114A1
Authority
SG
Singapore
Prior art keywords
ylsulfonylamino
quinoxalin
benzamide compounds
cck2
modulators
Prior art date
Application number
SG200701706-4A
Other languages
English (en)
Inventor
Brett D Allison
Michael D Hack
Victor K Phuong
Michael H Rabinowitz
Mark D Rosen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SG131114A1 publication Critical patent/SG131114A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632—Organic additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Ceramic Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG200701706-4A 2003-08-08 2004-08-04 2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators SG131114A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49407403P 2003-08-08 2003-08-08

Publications (1)

Publication Number Publication Date
SG131114A1 true SG131114A1 (en) 2007-04-26

Family

ID=34193199

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200701706-4A SG131114A1 (en) 2003-08-08 2004-08-04 2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators

Country Status (33)

Country Link
US (3) US7304051B2 (fr)
EP (2) EP1651622B1 (fr)
JP (2) JP2007501842A (fr)
KR (1) KR20060060007A (fr)
CN (2) CN1863781A (fr)
AR (1) AR045930A1 (fr)
AT (2) ATE353322T1 (fr)
AU (2) AU2004265311A1 (fr)
BR (1) BRPI0413449A (fr)
CA (2) CA2534887A1 (fr)
CR (1) CR8229A (fr)
CY (1) CY1106486T1 (fr)
DE (2) DE602004015614D1 (fr)
DK (2) DK1651622T3 (fr)
EA (1) EA200600203A1 (fr)
EC (1) ECSP066355A (fr)
ES (2) ES2310294T3 (fr)
HR (1) HRP20080559T3 (fr)
IL (1) IL173591A0 (fr)
IS (1) IS8280A (fr)
LT (1) LT5410B (fr)
LV (1) LV13453B (fr)
MX (2) MXPA06001550A (fr)
NO (1) NO20061122L (fr)
NZ (1) NZ545030A (fr)
PL (2) PL1651622T3 (fr)
PT (2) PT1651621E (fr)
SG (1) SG131114A1 (fr)
SI (2) SI1651622T1 (fr)
TW (1) TW200521120A (fr)
UA (1) UA84025C2 (fr)
WO (2) WO2005016896A1 (fr)
ZA (1) ZA200601946B (fr)

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WO2005105788A1 (fr) * 2004-04-23 2005-11-10 Takeda San Diego, Inc. Derives d'indole et leur utilisation en tant qu'inhibiteurs de kinases
US7947833B2 (en) * 2004-08-04 2011-05-24 Janssen Pharmaceutica Nv Preparation of quinoxaline compounds
MX2007003623A (es) 2004-09-24 2007-09-11 Johnson & Johnson Compuestos sulfonamida.
FR2904317A1 (fr) 2006-07-27 2008-02-01 Inst Nat Sante Rech Med Analogues d'halogenobenzamides marques a titre de radiopharmaceutiques
US8592565B2 (en) * 2007-01-12 2013-11-26 The Board Of Trustees Of The Leland Stanford Junior University Preparation of azide-modified carbon surfaces for coupling to various species
US8247403B2 (en) * 2007-03-07 2012-08-21 Takeda Pharmaceutical Company Limited Benzoxazepine derivatives and use thereof
WO2008124518A1 (fr) * 2007-04-03 2008-10-16 Janssen Pharmaceutica N.V. Composés de sulfonamide d'oxo-dihydroisoindole comme modulateurs de récepteur cck2
EP2131245A3 (fr) * 2008-06-02 2012-08-01 ASML Netherlands BV Appareil lithographique et sa méthode de détermination de la focalisation
US8354557B2 (en) * 2008-06-17 2013-01-15 Concert Pharmaceuticals, Inc. Synthesis of deuterated morpholine derivatives
US20100305093A1 (en) * 2009-04-09 2010-12-02 Exelixis, Inc. Inhibitors of mTOR and Methods of Making and Using
KR20120083905A (ko) 2009-10-09 2012-07-26 자프겐 코포레이션 비만의 치료에 사용하기 위한 설폰 화합물
EP2590953B1 (fr) 2010-07-09 2014-10-29 Convergence Pharmaceuticals Limited Dérivés de tétrazole comme bloqueurs des canaux calciques
CN103249735B (zh) 2010-07-22 2016-04-06 扎夫根股份有限公司 三环化合物及其制备和使用方法
BR112013018771A2 (pt) 2011-01-26 2019-09-17 Zafgen Inc compostos de tetrazol e métodos para fazer e usar os mesmos
WO2012154679A1 (fr) 2011-05-06 2012-11-15 Zafgen Corporation Composés de sulfonamide pyrazole tricycliques et leurs procédés de fabrication et d'utilisation
US9290472B2 (en) 2011-05-06 2016-03-22 Zafgen, Inc. Partially saturated tricyclic compounds and methods of making and using same
CA2835195A1 (fr) 2011-05-06 2012-11-15 Zafgen, Inc. Composes de sulfonamide tricycliques et leurs procedes de fabrication et d'utilisation
US20120309796A1 (en) 2011-06-06 2012-12-06 Fariborz Firooznia Benzocycloheptene acetic acids
KR20140112565A (ko) 2012-01-18 2014-09-23 자프겐 인크. 삼환식 설폰아마이드 화합물 그리고 그의 제조방법 및 그를 이용하는 방법
US9440943B2 (en) 2012-01-18 2016-09-13 Zafgen, Inc. Tricyclic sulfone compounds and methods of making and using same
WO2013130962A1 (fr) * 2012-03-01 2013-09-06 Allergan, Inc. Dérivés de benzofuran-2-sulfonamide comme modulateurs de récepteurs de chimiokine
CA2890342A1 (fr) 2012-11-05 2014-05-08 Zafgen, Inc. Composes tricycliques et procedes de fabrication et d'utilisation associes
SG11201503521QA (en) 2012-11-05 2015-06-29 Zafgen Inc Methods of treating liver diseases
AU2013337288A1 (en) 2012-11-05 2015-05-21 Zafgen, Inc. Tricyclic compounds for use in the treatment and/or control of obesity
JP6361168B2 (ja) * 2013-06-17 2018-07-25 Jsr株式会社 液晶配向剤、液晶配向膜、液晶表示素子、液晶表示素子の製造方法、重合体及び化合物
CN103524386B (zh) * 2013-10-24 2016-05-18 江苏鼎龙科技有限公司 2-氨基-4-甲磺酰胺甲基苯甲酸甲酯的制备方法
WO2015077572A1 (fr) 2013-11-22 2015-05-28 CL BioSciences LLC Antagonistes de gastrine (eg yf476, nétazépide) pour le traitement et la prévention de l'ostéoporose
KR20170016754A (ko) * 2015-08-04 2017-02-14 씨제이헬스케어 주식회사 크로마논 유도체의 신규한 제조방법
CN106565509A (zh) * 2016-11-03 2017-04-19 江苏鼎龙科技有限公司 2‑氨基‑4‑甲氨基苯甲酸甲酯盐酸盐的制备方法
KR101894091B1 (ko) 2018-01-23 2018-08-31 씨제이헬스케어 주식회사 크로마논 유도체의 신규한 제조방법
CN108218806B (zh) * 2018-04-02 2019-03-01 上海馨远医药科技有限公司 一种n-叔丁氧羰基吗啉-3-羧酸的制备方法
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BRPI0413449A (pt) * 2003-08-08 2006-10-17 Janssen Pharmaceutica Nv compostos de quinoxalina
MX2007003623A (es) * 2004-09-24 2007-09-11 Johnson & Johnson Compuestos sulfonamida.

Also Published As

Publication number Publication date
DE602004004663T2 (de) 2007-11-22
CA2534887A1 (fr) 2005-02-24
ATE353322T1 (de) 2007-02-15
DE602004004663D1 (de) 2007-03-22
US7288651B2 (en) 2007-10-30
US20050038032A1 (en) 2005-02-17
TW200521120A (en) 2005-07-01
PT1651622E (pt) 2007-04-30
DE602004015614D1 (de) 2008-09-18
PL1651622T3 (pl) 2007-07-31
PL1651621T3 (pl) 2009-01-30
ES2310294T3 (es) 2009-01-01
US7563895B2 (en) 2009-07-21
NO20061122L (no) 2006-05-04
EP1651621B1 (fr) 2008-08-06
AU2004265312B2 (en) 2010-05-20
CR8229A (es) 2008-09-10
IL173591A0 (en) 2006-07-05
KR20060060007A (ko) 2006-06-02
MXPA06001550A (es) 2006-09-04
CY1106486T1 (el) 2012-01-25
CN1863781A (zh) 2006-11-15
EP1651621A1 (fr) 2006-05-03
EP1651622B1 (fr) 2007-02-07
CA2534885C (fr) 2013-06-04
EP1651622A1 (fr) 2006-05-03
WO2005016896A1 (fr) 2005-02-24
IS8280A (is) 2006-01-31
AR045930A1 (es) 2005-11-16
CA2534885A1 (fr) 2005-02-24
ECSP066355A (es) 2006-08-30
ES2281834T3 (es) 2007-10-01
SI1651622T1 (sl) 2007-06-30
US20050043310A1 (en) 2005-02-24
LV13453B (en) 2007-02-20
WO2005016897A1 (fr) 2005-02-24
LT5410B (lt) 2007-03-26
EA200600203A1 (ru) 2006-08-25
ATE403650T1 (de) 2008-08-15
US20080076918A1 (en) 2008-03-27
AU2004265311A1 (en) 2005-02-24
DK1651622T3 (da) 2007-05-07
JP2007501841A (ja) 2007-02-01
UA84025C2 (en) 2008-09-10
MXPA06001482A (es) 2006-09-04
CN1863782A (zh) 2006-11-15
NZ545030A (en) 2009-08-28
PT1651621E (pt) 2008-09-30
DK1651621T3 (da) 2008-11-10
JP4818110B2 (ja) 2011-11-16
LT2006017A (en) 2006-11-27
JP2007501842A (ja) 2007-02-01
BRPI0413449A (pt) 2006-10-17
HRP20080559T3 (en) 2009-01-31
SI1651621T1 (sl) 2008-12-31
AU2004265312A1 (en) 2005-02-24
US7304051B2 (en) 2007-12-04
ZA200601946B (en) 2007-05-30

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