SG115536A1 - Processes and intermediates for preparing anti-cancer compounds - Google Patents

Processes and intermediates for preparing anti-cancer compounds

Info

Publication number
SG115536A1
SG115536A1 SG200302185A SG200302185A SG115536A1 SG 115536 A1 SG115536 A1 SG 115536A1 SG 200302185 A SG200302185 A SG 200302185A SG 200302185 A SG200302185 A SG 200302185A SG 115536 A1 SG115536 A1 SG 115536A1
Authority
SG
Singapore
Prior art keywords
intermediates
processes
preparing anti
cancer compounds
cancer
Prior art date
Application number
SG200302185A
Other languages
English (en)
Inventor
Shelton Lehner Richard
Norris Timothy
Paul Santafianos Dinos
Original Assignee
Pfizer Prod Inc
Osi Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc, Osi Pharm Inc filed Critical Pfizer Prod Inc
Publication of SG115536A1 publication Critical patent/SG115536A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B15/00—Obtaining copper
    • C22B15/0002—Preliminary treatment
    • C22B15/0004—Preliminary treatment without modification of the copper constituent
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B15/00—Obtaining copper
    • C22B15/0063—Hydrometallurgy
    • C22B15/0065—Leaching or slurrying
    • C22B15/0067—Leaching or slurrying with acids or salts thereof
    • C22B15/0071—Leaching or slurrying with acids or salts thereof containing sulfur
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P10/00—Technologies related to metal processing
    • Y02P10/20—Recycling

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG200302185A 1999-03-31 2000-03-27 Processes and intermediates for preparing anti-cancer compounds SG115536A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12707299P 1999-03-31 1999-03-31

Publications (1)

Publication Number Publication Date
SG115536A1 true SG115536A1 (en) 2005-10-28

Family

ID=22428179

Family Applications (2)

Application Number Title Priority Date Filing Date
SG200302185A SG115536A1 (en) 1999-03-31 2000-03-27 Processes and intermediates for preparing anti-cancer compounds
SG200001746A SG121687A1 (en) 1999-03-31 2000-03-27 Processes and intermediates for preparing anti-cancer compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG200001746A SG121687A1 (en) 1999-03-31 2000-03-27 Processes and intermediates for preparing anti-cancer compounds

Country Status (50)

Country Link
US (1) US6476040B1 (de)
EP (1) EP1044969B1 (de)
JP (2) JP3420549B2 (de)
KR (2) KR100430210B1 (de)
CN (2) CN1215061C (de)
AP (2) AP1265A (de)
AR (1) AR018705A1 (de)
AT (1) ATE348098T1 (de)
AU (2) AU781402B2 (de)
BG (1) BG65194B1 (de)
BR (1) BRPI0001486B8 (de)
CA (2) CA2427221C (de)
CO (1) CO5160273A1 (de)
CR (1) CR6165A (de)
CZ (1) CZ299426B6 (de)
DE (1) DE60032275T2 (de)
DK (1) DK1044969T3 (de)
DZ (1) DZ3030A1 (de)
EA (3) EA005892B1 (de)
EE (1) EE04589B1 (de)
EG (1) EG22506A (de)
ES (1) ES2278578T3 (de)
GE (1) GEP20022653B (de)
GT (1) GT200000037A (de)
HK (1) HK1029790A1 (de)
HR (1) HRP20000182B1 (de)
HU (1) HU227698B1 (de)
ID (1) ID25427A (de)
IL (2) IL135245A0 (de)
IS (1) IS2468B (de)
MA (1) MA25087A1 (de)
MY (1) MY136270A (de)
NO (2) NO321952B1 (de)
NZ (2) NZ503683A (de)
OA (1) OA11335A (de)
PA (1) PA8491901A1 (de)
PE (1) PE20001599A1 (de)
PL (1) PL339330A1 (de)
PT (1) PT1044969E (de)
RS (1) RS49836B (de)
SG (2) SG115536A1 (de)
SK (1) SK287339B6 (de)
SV (1) SV2002000047A (de)
TN (1) TNSN00064A1 (de)
TR (1) TR200000837A2 (de)
TW (1) TW553939B (de)
UA (2) UA80955C2 (de)
UY (1) UY26086A1 (de)
YU (1) YU13200A (de)
ZA (1) ZA200001586B (de)

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UA74803C2 (uk) * 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
EP1415987B1 (de) 2000-10-20 2007-02-28 Eisai R&D Management Co., Ltd. Stickstoff-enthaltende aromatische ringverbindungen zur behandlung von tumorerkrankungen
AU2002350105A1 (en) 2001-06-21 2003-01-08 Ariad Pharmaceuticals, Inc. Novel quinazolines and uses thereof
US7078409B2 (en) 2002-03-28 2006-07-18 Beta Pharma, Inc. Fused quinazoline derivatives useful as tyrosine kinase inhibitors
CA2491191C (en) 2002-07-15 2014-02-04 Exelixis, Inc. Receptor-type kinase modulators and methods of use
US7148231B2 (en) 2003-02-17 2006-12-12 Hoffmann-La Roche Inc. [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride polymorph
US7994159B2 (en) 2003-03-10 2011-08-09 Eisai R&D Management Co., Ltd. c-Kit kinase inhibitor
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
EP1660092A2 (de) 2003-07-03 2006-05-31 Myriad Genetics, Inc. 4-arylamino-chinazoline als aktivatoren von caspasen und apoptose-auslöser
WO2006074147A2 (en) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
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JP4638436B2 (ja) 2003-09-26 2011-02-23 エグゼリクシス， インコーポレイテッド ｃ−Ｍｅｔモジュレーターおよびその使用
JP4303726B2 (ja) 2003-11-11 2009-07-29 エーザイ・アール・アンド・ディー・マネジメント株式会社 ウレア誘導体およびその製造方法
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JP6757959B2 (ja) 2015-06-16 2020-09-23 株式会社 ＰＲＩＳＭ ＢｉｏＬａｂ 抗がん剤
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Also Published As

Publication number Publication date
HUP0001353A3 (en) 2002-01-28
AP1265A (en) 2004-03-26
HU227698B1 (en) 2011-12-28
JP4074509B2 (ja) 2008-04-09
CR6165A (es) 2008-10-10
MY136270A (en) 2008-09-30
AU781402B2 (en) 2005-05-19
DE60032275T2 (de) 2007-07-12
UA80955C2 (en) 2007-11-26
DE60032275D1 (de) 2007-01-25
HU0001353D0 (en) 2000-06-28
CN1215061C (zh) 2005-08-17
UY26086A1 (es) 2000-10-31
BG104278A (en) 2001-08-31
AU2005201494A1 (en) 2005-05-05
NO321952B1 (no) 2006-07-24
SK287339B6 (sk) 2010-07-07
ES2278578T3 (es) 2007-08-16
RS49836B (sr) 2008-08-07
CO5160273A1 (es) 2002-05-30
EE04589B1 (et) 2006-02-15
EA200201245A1 (ru) 2003-04-24
EG22506A (en) 2003-03-31
EP1044969A2 (de) 2000-10-18
ID25427A (id) 2000-10-05
IS2468B (is) 2008-12-15
CZ299426B6 (cs) 2008-07-23
IL135245A0 (en) 2001-05-20
GT200000037A (es) 2001-09-21
CN1276370A (zh) 2000-12-13
MA25087A1 (fr) 2000-10-01
NO20054715L (no) 2000-10-02
KR100430209B1 (ko) 2004-05-03
EP1044969A3 (de) 2000-11-29
NO20001648D0 (no) 2000-03-30
DK1044969T3 (da) 2007-04-23
TR200000837A2 (tr) 2000-11-21
EA005892B1 (ru) 2005-06-30
AR018705A1 (es) 2001-11-28
EA200201244A1 (ru) 2003-04-24
CZ20001155A3 (cs) 2001-03-14
PT1044969E (pt) 2007-05-31
SV2002000047A (es) 2002-01-23
HRP20000182A2 (en) 2001-04-30
AP1655A (en) 2006-09-01
IS5411A (is) 2000-10-02
BG65194B1 (bg) 2007-06-29
CA2427221C (en) 2008-09-16
SK4442000A3 (en) 2000-10-09
KR20020084903A (ko) 2002-11-13
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JP3420549B2 (ja) 2003-06-23
PE20001599A1 (es) 2001-01-18
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ATE348098T1 (de) 2007-01-15
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AU2005201494B2 (en) 2008-02-07
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NO324745B1 (no) 2007-12-03
TNSN00064A1 (fr) 2005-11-10
EA004654B1 (ru) 2004-06-24
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BRPI0001486B1 (pt) 2019-01-29
JP2003176274A (ja) 2003-06-24
KR20010014658A (ko) 2001-02-26
NZ512818A (en) 2003-01-31
DZ3030A1 (fr) 2004-03-27
CA2302965A1 (en) 2000-09-30
EA005561B1 (ru) 2005-04-28
CN100351242C (zh) 2007-11-28
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IL168036A (en) 2006-12-10
UA70928C2 (uk) 2004-11-15

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