SG11201903938XA - Acylated glp-1/glp-2 dual agonists - Google Patents

Acylated glp-1/glp-2 dual agonists

Info

Publication number
SG11201903938XA
SG11201903938XA SG11201903938XA SG11201903938XA SG11201903938XA SG 11201903938X A SG11201903938X A SG 11201903938XA SG 11201903938X A SG11201903938X A SG 11201903938XA SG 11201903938X A SG11201903938X A SG 11201903938XA SG 11201903938X A SG11201903938X A SG 11201903938XA
Authority
SG
Singapore
Prior art keywords
glp
international
pct
glucagon
prophylaxis
Prior art date
Application number
SG11201903938XA
Other languages
English (en)
Inventor
Larsen Bjarne Due
Jonathan Griffin
Lise Giehm
Alistair Vincent Gordon Edwards
Original Assignee
Zealand Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zealand Pharma As filed Critical Zealand Pharma As
Publication of SG11201903938XA publication Critical patent/SG11201903938XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
SG11201903938XA 2016-12-09 2017-12-11 Acylated glp-1/glp-2 dual agonists SG11201903938XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201600757 2016-12-09
PCT/EP2017/082290 WO2018104561A1 (fr) 2016-12-09 2017-12-11 Agonistes doubles de glp-1/glp-2 acylés

Publications (1)

Publication Number Publication Date
SG11201903938XA true SG11201903938XA (en) 2019-05-30

Family

ID=61005766

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201903938XA SG11201903938XA (en) 2016-12-09 2017-12-11 Acylated glp-1/glp-2 dual agonists
SG10201911851VA SG10201911851VA (en) 2016-12-09 2017-12-11 Acylated glp-1/glp-2 dual agonists

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201911851VA SG10201911851VA (en) 2016-12-09 2017-12-11 Acylated glp-1/glp-2 dual agonists

Country Status (16)

Country Link
US (4) US20190142904A1 (fr)
EP (1) EP3551651B1 (fr)
JP (2) JP6563614B1 (fr)
KR (1) KR102502040B1 (fr)
CN (2) CN117384274A (fr)
AU (1) AU2017371516C1 (fr)
BR (1) BR112019010624A2 (fr)
CA (1) CA3043151A1 (fr)
CL (1) CL2019001552A1 (fr)
CO (1) CO2019005924A2 (fr)
IL (1) IL266219B2 (fr)
MX (1) MX2019006486A (fr)
PE (1) PE20191083A1 (fr)
RU (1) RU2753193C2 (fr)
SG (2) SG11201903938XA (fr)
WO (1) WO2018104561A1 (fr)

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AU2020293576A1 (en) 2019-06-14 2021-11-04 Zealand Pharma A/S Pharmaceutical parenteral composition of dual GLP1/2 agonist
WO2021071837A1 (fr) 2019-10-07 2021-04-15 Kallyope, Inc. Agonistes de gpr119
WO2021198196A1 (fr) 2020-03-30 2021-10-07 Zealand Pharma A/S Agonistes doubles de glp-1/glp-2
EP4126004A1 (fr) 2020-03-30 2023-02-08 Zealand Pharma A/S Combinaison d'agonistes
CA3178994A1 (fr) 2020-05-19 2021-11-25 Iyassu Sebhat Activateurs d'ampk
CN116390925A (zh) 2020-06-26 2023-07-04 卡尔优普公司 Ampk活化剂
EP4262746A1 (fr) 2020-12-16 2023-10-25 Zealand Pharma A/S Composition pharmaceutique d'agonistes doubles de glp-1/glp-2
WO2022129311A1 (fr) 2020-12-16 2022-06-23 Zealand Pharma A/S Composition pharmaceutique de doubles agonistes de glp-1/glp-2
TW202241492A (zh) 2020-12-16 2022-11-01 丹麥商西蘭製藥公司 Ｇｌｐ－１／ｇｌｐ－２雙重促效劑之醫藥組合物
EP4294424A1 (fr) 2021-02-18 2023-12-27 Zealand Pharma A/S Composition pour le traitement du syndrome de l'intestin court
WO2023031380A1 (fr) 2021-09-03 2023-03-09 Zealand Pharma A/S Régime posologique
WO2023111273A1 (fr) * 2021-12-17 2023-06-22 Bainan Biotech Aps Agonistes doubles peptidiques de gipr et glp2r
WO2023132609A1 (fr) * 2022-01-05 2023-07-13 주식회사 휴온스랩 Dérivé peptidique d'acide gras à action prolongée et son utilisation
CN116655772A (zh) * 2022-02-18 2023-08-29 成都奥达生物科技有限公司 一种长效的glp-1/glp-2双激动剂化合物
WO2024061919A1 (fr) 2022-09-19 2024-03-28 Zealand Pharma A/S Polythérapie

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CN117384274A (zh) 2024-01-12
US20190142904A1 (en) 2019-05-16
JP6563614B1 (ja) 2019-08-21
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RU2019121253A3 (fr) 2021-01-21
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