SG10201907775QA - Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded tumour antigen - Google Patents
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded tumour antigenInfo
- Publication number
- SG10201907775QA SG10201907775QA SG10201907775QA SG10201907775QA SG10201907775QA SG 10201907775Q A SG10201907775Q A SG 10201907775QA SG 10201907775Q A SG10201907775Q A SG 10201907775QA SG 10201907775Q A SG10201907775Q A SG 10201907775QA SG 10201907775Q A SG10201907775Q A SG 10201907775QA
- Authority
- SG
- Singapore
- Prior art keywords
- nucleic acid
- sequence
- coding
- poly
- expression
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 6
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 108010033040 Histones Proteins 0.000 title abstract 4
- 108091034057 RNA (poly(A)) Proteins 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 230000008488 polyadenylation Effects 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
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