SG10201607778XA - Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use - Google Patents

Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use

Info

Publication number
SG10201607778XA
SG10201607778XA SG10201607778XA SG10201607778XA SG10201607778XA SG 10201607778X A SG10201607778X A SG 10201607778XA SG 10201607778X A SG10201607778X A SG 10201607778XA SG 10201607778X A SG10201607778X A SG 10201607778XA SG 10201607778X A SG10201607778X A SG 10201607778XA
Authority
SG
Singapore
Prior art keywords
regions
methods
dengue virus
polypeptides containing
virus antibodies
Prior art date
Application number
SG10201607778XA
Other languages
English (en)
Inventor
Zenjiro Sampei
Xing'er Christine Koo
Katja Fink
Roland Zuest
Original Assignee
Chugai Pharmaceutical Co Ltd
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Agency Science Tech & Res filed Critical Chugai Pharmaceutical Co Ltd
Priority to SG10201607778XA priority Critical patent/SG10201607778XA/en
Priority to KR1020217028717A priority patent/KR20210112418A/ko
Priority to CN202310300605.1A priority patent/CN116375853A/zh
Priority to SG11201901684XA priority patent/SG11201901684XA/en
Priority to RU2019110752A priority patent/RU2758596C2/ru
Priority to CN201780056694.2A priority patent/CN109790217B/zh
Priority to US16/333,736 priority patent/US10604561B2/en
Priority to TW110102784A priority patent/TW202124431A/zh
Priority to ARP170102564A priority patent/AR109536A1/es
Priority to TW112108742A priority patent/TW202348624A/zh
Priority to KR1020197009118A priority patent/KR102301948B1/ko
Priority to CA3036505A priority patent/CA3036505A1/en
Priority to AU2017326922A priority patent/AU2017326922B2/en
Priority to BR112019004770A priority patent/BR112019004770A2/pt
Priority to MYPI2019001063A priority patent/MY194289A/en
Priority to IL306084A priority patent/IL306084A/en
Priority to EP17851188.7A priority patent/EP3512879A4/en
Priority to PE2019000518A priority patent/PE20190733A1/es
Priority to PCT/SG2017/050465 priority patent/WO2018052375A1/en
Priority to SG10202103171PA priority patent/SG10202103171PA/en
Priority to IL265290A priority patent/IL265290B2/en
Priority to MX2019003057A priority patent/MX2019003057A/es
Priority to JP2019514822A priority patent/JP6913161B2/ja
Priority to TW106131859A priority patent/TWI714805B/zh
Publication of SG10201607778XA publication Critical patent/SG10201607778XA/en
Priority to PH12019500485A priority patent/PH12019500485A1/en
Priority to CL2019000640A priority patent/CL2019000640A1/es
Priority to CONC2019/0002482A priority patent/CO2019002482A2/es
Priority to MX2023009084A priority patent/MX2023009084A/es
Priority to ECSENADI201918654A priority patent/ECSP19018654A/es
Priority to US16/435,979 priority patent/US10844113B2/en
Priority to US17/066,092 priority patent/US11780908B2/en
Priority to JP2021113980A priority patent/JP7390336B2/ja
Priority to JP2023130579A priority patent/JP2023145788A/ja
Priority to US18/453,418 priority patent/US20240018219A1/en
Priority to AU2024202535A priority patent/AU2024202535A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
SG10201607778XA 2016-09-16 2016-09-16 Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use SG10201607778XA (en)

Priority Applications (35)

Application Number Priority Date Filing Date Title
SG10201607778XA SG10201607778XA (en) 2016-09-16 2016-09-16 Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
PE2019000518A PE20190733A1 (es) 2016-09-16 2017-09-15 Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y metodos de uso
PCT/SG2017/050465 WO2018052375A1 (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
SG11201901684XA SG11201901684XA (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
CN202310300605.1A CN116375853A (zh) 2016-09-16 2017-09-15 抗登革热病毒抗体、含有变体fc区域的多肽及使用方法
CN201780056694.2A CN109790217B (zh) 2016-09-16 2017-09-15 抗登革热病毒抗体、含有变体fc区域的多肽及使用方法
SG10202103171PA SG10202103171PA (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
TW110102784A TW202124431A (zh) 2016-09-16 2017-09-15 抗登革熱病毒抗體、含有變異Fc區的多肽及使用方法
ARP170102564A AR109536A1 (es) 2016-09-16 2017-09-15 Anticuerpos contra el virus del dengue, polipéptidos que contienen regiones fc variantes, y métodos de uso
TW112108742A TW202348624A (zh) 2016-09-16 2017-09-15 抗登革熱病毒抗體、含有變異Fc區的多肽及使用方法
KR1020197009118A KR102301948B1 (ko) 2016-09-16 2017-09-15 항-뎅기 바이러스 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
CA3036505A CA3036505A1 (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
AU2017326922A AU2017326922B2 (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant Fc regions, and methods of use
BR112019004770A BR112019004770A2 (pt) 2016-09-16 2017-09-15 anticorpos do vírus antidengue, polipeptídeos contendo regiões fc variantes, e métodos de uso
MYPI2019001063A MY194289A (en) 2016-09-16 2017-09-15 Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, and Methods of use
IL306084A IL306084A (en) 2016-09-16 2017-09-15 Antibodies against dengue virus, proteins containing Fc regions and methods of their use
EP17851188.7A EP3512879A4 (en) 2016-09-16 2017-09-15 DENGUE ANTIVIRUS ANTIBODIES, POLYPEPTIDES CONTAINING FC REGION VARIANTS, AND METHODS OF USE
KR1020217028717A KR20210112418A (ko) 2016-09-16 2017-09-15 항-뎅기 바이러스 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
RU2019110752A RU2758596C2 (ru) 2016-09-16 2017-09-15 Антитела к вирусу денге, полипептиды, содержащие варианты fc-областей, и способы их применения
US16/333,736 US10604561B2 (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant Fc regions, and methods of use
IL265290A IL265290B2 (en) 2016-09-16 2017-09-15 Antibodies against dengue virus, proteins containing Fc regions and methods of their use
MX2019003057A MX2019003057A (es) 2016-09-16 2017-09-15 Anticuerpos anti-virus del dengue, polipeptidos que contienen regiones fc variantes y metodos de uso.
JP2019514822A JP6913161B2 (ja) 2016-09-16 2017-09-15 抗デングウイルス抗体、変異型Ｆｃ領域を含むポリペプチド、およびその使用方法
TW106131859A TWI714805B (zh) 2016-09-16 2017-09-15 抗登革熱病毒抗體、含有變異Fc區的多肽及使用方法
PH12019500485A PH12019500485A1 (en) 2016-09-16 2019-03-05 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
CL2019000640A CL2019000640A1 (es) 2016-09-16 2019-03-13 Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso.
CONC2019/0002482A CO2019002482A2 (es) 2016-09-16 2019-03-15 Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso
MX2023009084A MX2023009084A (es) 2016-09-16 2019-03-15 Anticuerpos anti-virus del dengue, polipeptidos que contienen regiones fc variantes y metodos de uso.
ECSENADI201918654A ECSP19018654A (es) 2016-09-16 2019-03-15 Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso
US16/435,979 US10844113B2 (en) 2016-09-16 2019-06-10 Anti-dengue virus antibodies, polypeptides containing variant Fc regions, and methods of use
US17/066,092 US11780908B2 (en) 2016-09-16 2020-10-08 Anti-dengue virus antibodies, polypeptides containing variant FC regions, and methods of use
JP2021113980A JP7390336B2 (ja) 2016-09-16 2021-07-09 抗デングウイルス抗体、変異型Ｆｃ領域を含むポリペプチド、およびその使用方法
JP2023130579A JP2023145788A (ja) 2016-09-16 2023-08-10 抗デングウイルス抗体、変異型Ｆｃ領域を含むポリペプチド、およびその使用方法
US18/453,418 US20240018219A1 (en) 2016-09-16 2023-08-22 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
AU2024202535A AU2024202535A1 (en) 2016-09-16 2024-04-17 Anti-dengue virus antibodies, polypeptides containing variant Fc regions, and methods of use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG10201607778XA SG10201607778XA (en) 2016-09-16 2016-09-16 Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use

Publications (1)

Publication Number Publication Date
SG10201607778XA true SG10201607778XA (en) 2018-04-27

Family

ID=61618863

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201607778XA SG10201607778XA (en) 2016-09-16 2016-09-16 Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
SG11201901684XA SG11201901684XA (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
SG10202103171PA SG10202103171PA (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG11201901684XA SG11201901684XA (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use
SG10202103171PA SG10202103171PA (en) 2016-09-16 2017-09-15 Anti-dengue virus antibodies, polypeptides containing variant fc regions, and methods of use

Country Status (21)

Country Link
US (4) US10604561B2 (ja)
EP (1) EP3512879A4 (ja)
JP (3) JP6913161B2 (ja)
KR (2) KR20210112418A (ja)
CN (2) CN116375853A (ja)
AR (1) AR109536A1 (ja)
AU (2) AU2017326922B2 (ja)
BR (1) BR112019004770A2 (ja)
CA (1) CA3036505A1 (ja)
CL (1) CL2019000640A1 (ja)
CO (1) CO2019002482A2 (ja)
EC (1) ECSP19018654A (ja)
IL (2) IL265290B2 (ja)
MX (2) MX2019003057A (ja)
MY (1) MY194289A (ja)
PE (1) PE20190733A1 (ja)
PH (1) PH12019500485A1 (ja)
RU (1) RU2758596C2 (ja)
SG (3) SG10201607778XA (ja)
TW (3) TW202124431A (ja)
WO (1) WO2018052375A1 (ja)

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ES2566957T3 (es) 2007-09-26 2016-04-18 Chugai Seiyaku Kabushiki Kaisha Región constante de anticuerpo modificado
CN105451763B (zh) 2013-03-15 2021-06-18 武田疫苗股份有限公司 用于疫苗中的登革热病毒嵌合式构建物的组合物及方法
EA201791754A1 (ru) 2015-02-05 2019-01-31 Чугаи Сейяку Кабусики Кайся АНТИТЕЛА, СОДЕРЖАЩИЕ ЗАВИСЯЩИЙ ОТ КОНЦЕНТРАЦИИ ИОНОВ АНТИГЕНСВЯЗЫВАЮЩИЙ ДОМЕН, ВАРИАНТЫ Fc-ОБЛАСТИ, IL-8-СВЯЗЫВАЮЩИЕ АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
CA3026050A1 (en) 2016-08-05 2018-02-08 Chugai Seiyaku Kabushiki Kaisha Composition for prophylaxis or treatment of il-8 related diseases
SG10201607778XA (en) 2016-09-16 2018-04-27 Chugai Pharmaceutical Co Ltd Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
EP3765494A4 (en) * 2018-03-15 2022-03-23 Chugai Seiyaku Kabushiki Kaisha ANTI-DENGUE VIRUS ANTIBODIES WITH CROSS-REACTIVITY AGAINST ZIKA VIRUS AND METHODS OF USE
US11464815B2 (en) 2018-09-05 2022-10-11 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
CA3111332A1 (en) 2018-09-05 2020-03-12 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
WO2022034920A1 (en) * 2020-08-14 2022-02-17 Chugai Seiyaku Kabushiki Kaisha One-armed antigen-binding molecules and uses thereof
WO2023013618A1 (ja) * 2021-08-02 2023-02-09 国立研究開発法人国立長寿医療研究センター ヒトアストロウイルスの感染レセプターとその応用
CN114410588B (zh) * 2022-01-29 2022-11-04 西安电子科技大学 一种α1β1整合素依赖增强型CAR巨噬细胞及其制备方法和应用

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