SG10201505723UA - Methods for detecting signatures of disease or conditions in bodily fluids - Google Patents

Methods for detecting signatures of disease or conditions in bodily fluids

Info

Publication number
SG10201505723UA
SG10201505723UA SG10201505723UA SG10201505723UA SG10201505723UA SG 10201505723U A SG10201505723U A SG 10201505723UA SG 10201505723U A SG10201505723U A SG 10201505723UA SG 10201505723U A SG10201505723U A SG 10201505723UA SG 10201505723U A SG10201505723U A SG 10201505723UA
Authority
SG
Singapore
Prior art keywords
disease
conditions
methods
bodily fluids
detecting signatures
Prior art date
Application number
SG10201505723UA
Other languages
English (en)
Inventor
I Kassis Amin
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of SG10201505723UA publication Critical patent/SG10201505723UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
SG10201505723UA 2010-07-23 2011-07-22 Methods for detecting signatures of disease or conditions in bodily fluids SG10201505723UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36700610P 2010-07-23 2010-07-23

Publications (1)

Publication Number Publication Date
SG10201505723UA true SG10201505723UA (en) 2015-09-29

Family

ID=45497477

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2013004791A SG187159A1 (en) 2010-07-23 2011-07-22 Methods for detecting signatures of disease or conditions in bodily fluids
SG10201505723UA SG10201505723UA (en) 2010-07-23 2011-07-22 Methods for detecting signatures of disease or conditions in bodily fluids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2013004791A SG187159A1 (en) 2010-07-23 2011-07-22 Methods for detecting signatures of disease or conditions in bodily fluids

Country Status (12)

Country Link
US (5) US20120053073A1 (fr)
EP (2) EP2596132A4 (fr)
JP (5) JP2013538565A (fr)
KR (1) KR20130041961A (fr)
CN (2) CN103119179A (fr)
AU (2) AU2011280996B2 (fr)
BR (1) BR112013001754A2 (fr)
CA (1) CA2806291C (fr)
EA (1) EA201390150A1 (fr)
MX (1) MX361944B (fr)
SG (2) SG187159A1 (fr)
WO (1) WO2012012693A2 (fr)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0906858B8 (pt) 2008-01-18 2021-07-27 Harvard College métodos in vitro para detectar a presença de uma célula de câncer em um indivíduo e para identificar uma assinatura específica de tumor em um indivíduo tendo câncer.
EP2596116A4 (fr) 2010-07-23 2014-03-19 Harvard College Procédés de détection de maladies/pathologies auto-immunes ou liées au système immunitaire
AU2011280936A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting prenatal or pregnancy-related diseases or conditions
KR101212714B1 (ko) * 2011-01-26 2013-01-22 계명대학교 산학협력단 계층적 퍼지 추론에 기반한 임상진단 지원방법 및 그 시스템
AU2013211850B8 (en) 2012-01-27 2017-06-29 The Board Of Trustees Of The Leland Stanford Junior University Methods for profiling and quantitating cell-free RNA
US9220733B2 (en) 2012-03-19 2015-12-29 The Regents Of The University Of California Solubilization of antigen components for removal from tissues
WO2013162458A1 (fr) * 2012-04-24 2013-10-31 Wahren Herlenius Marie Utilisation de ro52 comme marqueur prédictif pour l'évolution d'une tumeur immuno-dérivée
WO2013173642A1 (fr) * 2012-05-18 2013-11-21 Sanford-Burnham Medical Research Institute Lipidomique à rendement élevé
CN104603289A (zh) * 2012-06-15 2015-05-06 哈里·斯泰利 检测疾病或病状的方法
BR112014031414A2 (pt) * 2012-06-15 2017-06-27 Stylli Harry métodos de detectar doenças ou condições utilizando células doentes circulantes
US11913065B2 (en) 2012-09-04 2024-02-27 Guardent Health, Inc. Systems and methods to detect rare mutations and copy number variation
EP2893040B1 (fr) 2012-09-04 2019-01-02 Guardant Health, Inc. Procédés pour détecter des mutations rares et une variation de nombre de copies
US10876152B2 (en) 2012-09-04 2020-12-29 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
EP3536807B1 (fr) * 2012-09-20 2023-11-29 The Chinese University of Hong Kong Détermination non invasive d'un méthylome d'une tumeur à partir du plasma
US10706957B2 (en) 2012-09-20 2020-07-07 The Chinese University Of Hong Kong Non-invasive determination of methylome of tumor from plasma
US9732390B2 (en) 2012-09-20 2017-08-15 The Chinese University Of Hong Kong Non-invasive determination of methylome of fetus or tumor from plasma
US20150252428A1 (en) * 2012-10-03 2015-09-10 Exosome Diagnostics, Inc. Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions
CN102912029A (zh) * 2012-11-06 2013-02-06 俞杨 一种检测人结核杆菌相关易感基因cish +1320位点的单核苷酸多态性的方法
GB201220573D0 (en) 2012-11-15 2013-01-02 Univ Central Lancashire Methods of diagnosing proliferative disorders
GB201302837D0 (en) * 2013-02-19 2013-04-03 Univ Singapore Therapeutic Agents
EP2965086A4 (fr) 2013-03-09 2017-02-08 Harry Stylli Procédés de détection du cancer de la prostate
US10494675B2 (en) 2013-03-09 2019-12-03 Cell Mdx, Llc Methods of detecting cancer
CN118028467A (zh) * 2013-03-14 2024-05-14 梅奥医学教育和研究基金会 检测赘生物
US10119978B2 (en) * 2013-03-15 2018-11-06 Wallac Oy System and method for determining risk of diabetes based on biochemical marker analysis
WO2014170497A2 (fr) * 2013-04-19 2014-10-23 Epiontis Gmbh Méthode d'identification de la composition cellulaire quantitative d'un échantillon biologique
CN103293321B (zh) * 2013-05-27 2015-05-13 北京大学 一种检测dna损伤诱导的早期核仁应激的试剂盒及其应用
CN103555818A (zh) * 2013-07-16 2014-02-05 中国人民解放军海军医学研究所 B细胞转位基因2作为低剂量电离辐射生物剂量计的应用
EP3024949B1 (fr) * 2013-07-24 2019-03-06 The Chinese University Of Hong Kong B3gnt5 comme biomarqueur de la prématurité
CN104374853A (zh) * 2013-08-14 2015-02-25 柯跃斌 高效液相色谱质谱联用检测dna氧化与dna甲基化的方法
US10745754B2 (en) 2013-11-27 2020-08-18 Bioscreening & Diagnostics Llc Method for predicting congenital heart defect
WO2015095359A1 (fr) * 2013-12-17 2015-06-25 Harry Stylli Méthodes de détection de maladies ou d'états pathologiques
JP6571665B2 (ja) 2013-12-28 2019-09-04 ガーダント ヘルス， インコーポレイテッド 遺伝的バリアントを検出するための方法およびシステム
JP6484636B2 (ja) 2014-01-16 2019-03-13 イラミーナ インコーポレーテッド 固相担体におけるアンプリコン調製および配列決定
CN106062215B (zh) * 2014-02-28 2020-09-22 国立研究开发法人国立癌研究中心 肾细胞癌的预后判定方法
ES2812753T3 (es) 2014-03-31 2021-03-18 Mayo Found Medical Education & Res Detección de neoplasma colorectal
MA39951A (fr) * 2014-05-09 2017-03-15 Lifecodexx Ag Détection de l'adn provenant d'un type spécifique de cellule et méthodes associées
EP2942400A1 (fr) 2014-05-09 2015-11-11 Lifecodexx AG Détection multiplexe d'ADN qui provient d'un type cellulaire spécifique
WO2015176066A2 (fr) * 2014-05-16 2015-11-19 Intermune, Inc. Protéine associée à lpa et expression d'arn
CN104101715A (zh) * 2014-07-15 2014-10-15 重庆医科大学附属儿童医院 检测dock8蛋白的试剂盒及非诊断目的检测dock8蛋白的方法
WO2016040843A1 (fr) * 2014-09-11 2016-03-17 Harry Stylli Procédés pour détecter le cancer de la prostate
CN104357559A (zh) * 2014-10-27 2015-02-18 同济大学 日本血吸虫雌虫发育调控关键核糖体蛋白的鉴定方法
CN104280478B (zh) * 2014-11-03 2016-03-30 天津中医药大学 内源性小分子物质在快速检测肾毒性方面的应用
JP2017538404A (ja) 2014-11-14 2017-12-28 リキッド ジェノミクス，インコーポレイティド 癌を診断及び／又は観察するための循環無細胞ｒｎａの使用
WO2016095093A1 (fr) * 2014-12-15 2016-06-23 天津华大基因科技有限公司 Méthode de dépistage d'une tumeur, procédé et dispositif de détection d'une variation de la région cible
US10030272B2 (en) 2015-02-27 2018-07-24 Mayo Foundation For Medical Education And Research Detecting gastrointestinal neoplasms
EP3316159A4 (fr) 2015-06-25 2019-08-14 Advanced Telecommunications Research Institute International Dispositif de prédiction reposant sur un système associé à plusieurs organes et programme de prédiction
WO2017040627A1 (fr) 2015-08-31 2017-03-09 Mayo Foundation For Medical Education And Research Détection de néoplasme gastrique
CA2998680C (fr) * 2015-09-17 2024-01-02 Consejo Superior De Investigaciones Cientificas Procede de detection de cellules circulantes dans des fluides corporels superficiels
US20170097355A1 (en) * 2015-10-06 2017-04-06 University Of Washington Biomarkers and methods to distinguish ovarian cancer from benign tumors
EP3168309B8 (fr) 2015-11-10 2020-06-03 Eurofins LifeCodexx GmbH Détection d'aneuploïdies chromosomiques foetales au moyen de régions d'adn qui sont méthylées de manière différentielle entre le foetus et la femme enceinte
WO2017097852A2 (fr) * 2015-12-07 2017-06-15 Zora Biosciences Oy Utilisation des céramides et des lpl dans le diagnostic des cvd
WO2017106768A1 (fr) 2015-12-17 2017-06-22 Guardant Health, Inc. Procédés de détermination du nombre de copies du gène tumoral par analyse d'adn acellulaire
CN105506083B (zh) * 2015-12-24 2018-10-19 孙梅芬 Capg在制备诊断帕金森症产品中的用途
CN205301177U (zh) * 2015-12-31 2016-06-08 深圳市贝沃德克生物技术研究院有限公司 家用肺炎支原体感染检测系统
WO2017122816A1 (fr) 2016-01-15 2017-07-20 公益財団法人がん研究会 Nouveau corps de fusion et procédé de détection de celui-ci
WO2017136603A1 (fr) 2016-02-02 2017-08-10 Guardant Health, Inc. Détection et diagnostic d'évolution d'un cancer
CN105842037B (zh) * 2016-03-21 2018-07-31 山东农业大学 一种同时显示肥大细胞与嗜酸性细胞的染色方法
CN109196119A (zh) 2016-03-29 2019-01-11 株式会社国际电气通信基础技术研究所 用以预防或治疗选自由肾功能减退、慢性肾病和肾衰竭组成的组中的至少一种疾病的活性组分的候选物质的筛选方法
EP3466446B1 (fr) 2016-03-29 2023-12-27 Karydo Therapeutix, Inc. Composition pharmaceutique ou composition alimentaire et procédé d'évaluation de l'effet d'un principe actif in vivo
US10370726B2 (en) 2016-04-14 2019-08-06 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasia
CN105784873B (zh) * 2016-05-06 2017-10-13 常熟市医学检验所 基于代谢组学的高尿酸性肾损伤早期诊断标志物及其应用
MX2018015184A (es) * 2016-06-07 2019-04-24 Univ Leland Stanford Junior Métodos para el diagnóstico de infecciones bacterianas y virales.
CN107144620A (zh) * 2017-03-31 2017-09-08 兰州百源基因技术有限公司 糖尿病肾病检测标志物
WO2018183747A1 (fr) * 2017-03-31 2018-10-04 The Regents Of The University Of California Identification d'antigène protéomique aléatoire
CN107328746B (zh) * 2017-06-14 2020-01-31 宁波大学 基于类核酸配位聚合物的多功能荧光生物传感器的制备及应用
US20200141948A1 (en) * 2017-06-21 2020-05-07 Korea Research Institute Of Bioscience And Biotechnology Method and kit for diagnosis of muscle weakness-related diseases using blood biomarker
WO2019018545A1 (fr) 2017-07-18 2019-01-24 The Research Foundation For The State University Of New York Biomarqueurs d'anévrisme intracrânien
AU2018312117B2 (en) * 2017-08-04 2022-05-12 Billiontoone, Inc. Sequencing output determination and analysis with target-associated molecules in quantification associated with biological targets
EP3665301B1 (fr) * 2017-08-09 2023-10-04 PamGene B.V. Procédé permettant de prédire la réponse d'un carcinome pulmonaire non à petites cellules chez des patients à un médicament
EP3713552A1 (fr) 2017-11-23 2020-09-30 Biosearch S.A. Procédé d'augmentation du taux d'implantation des embryons chez un sujet femelle souffrant du syndrome des ovaires polykystiques
CN109658980B (zh) * 2018-03-20 2023-05-09 上海交通大学医学院附属瑞金医院 一种粪便基因标志物的筛选及应用
KR102072504B1 (ko) * 2018-05-23 2020-02-03 중앙대학교 산학협력단 Dock8 유전자 단일염기다형성을 이용한 아토피 피부염 진단용 조성물과 검출 방법
WO2019232512A1 (fr) * 2018-06-01 2019-12-05 Musc Foundatiion For Research Development Analyse de glycanes de protéines et de cellules
CN108841928B (zh) * 2018-06-11 2021-11-23 河北医科大学 一种人类线粒体基因组甲基化检测试剂盒及其应用
BR112021003477A2 (pt) * 2018-06-14 2021-05-18 Metabolomycs, Inc. assinaturas metabolômicas para prever, diagnosticar e prognosticar várias doenças incluindo câncer
CN108796067B (zh) * 2018-07-03 2019-10-25 北京泱深生物信息技术有限公司 血液中maea基因的诊断新功能
CN109266734A (zh) * 2018-09-25 2019-01-25 深圳市人民医院 自身免疫性疾病诊断试剂盒和应用
CN109295230A (zh) * 2018-10-24 2019-02-01 福建翊善生物科技有限公司 一种基于ctDNA的多基因联合突变检测评估肿瘤动态变化的方法
EP3924972A4 (fr) 2019-02-14 2023-03-29 Mirvie, Inc. Procédé et systèmes de détermination d'un état associé à la grossesse chez un sujet
CN113853443A (zh) * 2019-03-08 2021-12-28 株式会社Neogentc 用于预测淋巴细胞的肿瘤反应性的标志物及其用途
CN109821029B (zh) * 2019-04-08 2020-12-15 浙江大学 Zdhhc21基因在制备白血病诱导分化治疗药物中的应用
KR102169901B1 (ko) * 2019-05-17 2020-10-26 연세대학교 산학협력단 Dna 메틸화를 이용한 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트
WO2020243589A1 (fr) * 2019-05-29 2020-12-03 Washington University Procédés de détection d'infections par clostridium difficile
WO2021041931A1 (fr) * 2019-08-28 2021-03-04 The Regents Of The University Of California Procédés de production de profils de méthylation de l'adn
CN110514847B (zh) * 2019-09-24 2022-06-10 北京市心肺血管疾病研究所 血清LysoPA在小儿扩张型心肌病预后中的应用
CN112697889B (zh) * 2019-10-22 2022-03-08 中国科学院大连化学物理研究所 一种血清代谢标志物的用途及检测试剂盒
CN111189683A (zh) * 2020-01-06 2020-05-22 中国科学院地质与地球物理研究所 一种离子探针液体样品靶的制备方法
CN111341448B (zh) * 2020-03-03 2023-12-19 西安交通大学 一种基于孟德尔随机化预测复杂疾病及表型相关代谢物的方法
CN111041089B (zh) * 2020-03-13 2020-06-19 广州微远基因科技有限公司 Covid-19感染的宿主标志物的应用
WO2021201111A1 (fr) * 2020-04-01 2021-10-07 あすか製薬株式会社 Procédé permettant de différencier la thyroïdite destructrice d'autres états pathologiques
CN111334572B (zh) * 2020-04-26 2020-10-27 江苏大学附属医院 Ctsz基因甲基化的新用途
CN112305220B (zh) * 2020-06-03 2021-07-23 四川大学华西第二医院 组织蛋白酶z在子痫前期的早期预警、诊断中的应用和产品
CN111679018B (zh) * 2020-08-14 2020-11-20 宝枫生物科技（北京）有限公司 用于诊断认知障碍的生物标记物及其应用
CN112305118B (zh) * 2020-10-30 2022-03-22 河北医科大学第二医院 L-辛酰基肉碱作为疾病诊断的生物标志物
CN112501175A (zh) * 2020-12-14 2021-03-16 南通大学 一种银屑病抑制基因及其应用
US11152103B1 (en) 2020-12-29 2021-10-19 Kpn Innovations, Llc. Systems and methods for generating an alimentary plan for managing musculoskeletal system disorders
CN113295874B (zh) * 2021-05-25 2022-03-04 广东源心再生医学有限公司 一种用于瓣膜性心脏病辅助诊断的新型标志物、辅助诊断的产品
CN113267394A (zh) * 2021-06-10 2021-08-17 谱天（天津）生物科技有限公司 用于蛋白质组质控的ffpe参考品、其制备方法及应用
CN113252910B (zh) * 2021-06-29 2022-05-17 中国人民解放军军事科学院军事医学研究院 Timp3在焦虑抑郁症诊断中的应用
WO2023279213A1 (fr) * 2021-07-09 2023-01-12 Uti Limited Partnership Profils métabolomiques pour la prédiction d'un résultat neurologique fonctionnel ou d'un décès suite à une lésion cérébrale traumatique grave
WO2023044118A1 (fr) * 2021-09-20 2023-03-23 Droplet Biosciences, Inc. Procédés d'évaluation de maladie à l'aide d'un fluide de drainage
WO2023250229A1 (fr) * 2022-06-23 2023-12-28 Oklahoma Medical Research Foundation Biomarqueurs d'auto-anticorps du syndrome de sjögren/de la maladie de sjögren négatif sans anticorps ro/ss-a
CN115575646B (zh) * 2022-11-21 2023-04-28 四川大学华西医院 一种代谢标志物组在制备预测癫痫发作的试剂盒中的用途
CN118518454B (zh) * 2024-07-23 2024-09-13 天津医科大学第二医院 一种适用于质谱检测的样本预处理装置

Family Cites Families (229)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4868103A (en) 1986-02-19 1989-09-19 Enzo Biochem, Inc. Analyte detection by means of energy transfer
US4843155A (en) 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
CA2087413A1 (fr) 1992-01-17 1993-07-18 Joseph R. Lakowicz Dosage immunologique fluorimetrique
JPH08509857A (ja) 1993-01-07 1996-10-22 シーケノム・インコーポレーテッド マススペクトロメトリーによるｄｎａ配列決定法
WO1994021686A1 (fr) 1993-03-19 1994-09-29 Northern Sydney Area Health Service Papp-a, son immunodetection et ses utilisations
US5594637A (en) 1993-05-26 1997-01-14 Base Ten Systems, Inc. System and method for assessing medical risk
US5498531A (en) 1993-09-10 1996-03-12 President And Fellows Of Harvard College Intron-mediated recombinant techniques and reagents
US5514598A (en) 1993-11-30 1996-05-07 Doody; Michael Prenatal detection of meconium
US6025395A (en) 1994-04-15 2000-02-15 Duke University Method of preventing or delaying the onset and progression of Alzheimer's disease and related disorders
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US6031088A (en) 1996-05-23 2000-02-29 Albert Einstein College Of Medicine Of Yeshiva University Polycystic kidney disease PKD2 gene and uses thereof
US20010051341A1 (en) 1997-03-04 2001-12-13 Isis Innovation Limited Non-invasive prenatal diagnosis
GB9704444D0 (en) 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US20020119118A1 (en) 1997-11-03 2002-08-29 Genentech, Inc. Novel polypeptides and nucleic acids encoding bolekine
WO2000040749A2 (fr) 1999-01-06 2000-07-13 Genenews Inc. Technique de detection de transcrits geniques dans le sang et leur utilisation
AU2005200170A1 (en) * 1999-03-05 2005-02-10 University Of Iowa Research Foundation Diagnostics and therapeutics for drusen associated ocular disorders
US6762032B1 (en) 1999-08-23 2004-07-13 Biocrystal, Ltd. Compositions, assay kits, and methods for use related to a disease condition comprising multiple sclerosis and/or a pro-MS immune response
AU2001275346A1 (en) 2000-06-05 2001-12-17 General Hospital Corporation Compositions, kits, and methods for identification and modulation of type i diabetes
DE50113102D1 (de) 2000-06-27 2007-11-22 Von Recklinghausen Ges E V Verfahren zur Ermittlung von Daten zur präsymptomatischen oder pränatalen Diagnose von Typ 1 Neurofibromatose
US6664056B2 (en) 2000-10-17 2003-12-16 The Chinese University Of Hong Kong Non-invasive prenatal monitoring
FR2816411B1 (fr) 2000-11-03 2003-07-04 Inst Nat Sante Rech Med Moyens de detection de la transformation pathologique de la proteine app et leurs applications
US20030064380A1 (en) * 2001-01-29 2003-04-03 The Center For Blood Research, Inc. Anergy-regulated molecules
US6753137B2 (en) 2001-01-31 2004-06-22 The Chinese University Of Hong Kong Circulating epstein-barr virus DNA in the serum of patients with gastric carcinoma
GB0104690D0 (en) 2001-02-26 2001-04-11 Cytogenetic Dna Services Ltd Diagnostic test
FR2824144B1 (fr) 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
DE10291986D2 (de) 2001-05-09 2004-04-15 Biovision Ag Verfahren zum Nachweis einer progredienten, chronisch-demenziellen Erkrankung, zugehörige Peptide und Nachweisreagenzien
WO2003019193A1 (fr) 2001-08-30 2003-03-06 Ciphergen Biosystems, Inc. Procede de diagnostic du syndrome nephrotique
US6927028B2 (en) 2001-08-31 2005-08-09 Chinese University Of Hong Kong Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA
US7744876B2 (en) 2002-04-09 2010-06-29 The Curators Of The University Of Missouri Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes
US7009038B2 (en) 2002-05-02 2006-03-07 Univ. Of Medicine & Dentistry Of N.J. pDJA1, a cardiac specific gene, corresponding proteins, and uses thereof
HUE039881T2 (hu) 2002-05-09 2019-02-28 Brigham & Womens Hospital Inc 1L1RL-1, mint egy kardiovaszkuláris betegség-marker
US20040009518A1 (en) 2002-05-14 2004-01-15 The Chinese University Of Hong Kong Methods for evaluating a disease condition by nucleic acid detection and fractionation
US7157235B2 (en) 2002-06-17 2007-01-02 St. Vincent's Hospital Sydney Limited Methods of diagnosis, prognosis and treatment of cardiovascular disease
WO2004005921A1 (fr) 2002-07-05 2004-01-15 Evotec Neurosciences Gmbh Utilisation diagnostique et therapeutique de proteine et de gene tb2 pour des maladies neurodegeneratives
FR2844279A1 (fr) 2002-09-06 2004-03-12 Inst Nat Sante Rech Med Moyens de detection des processus neurodegeneratifs et leurs applications
WO2004024098A2 (fr) 2002-09-16 2004-03-25 Abgenix, Inc. Methode de traitement de la nephrite faisant intervenir des anticorps anti-pdgf-dd
WO2004030522A2 (fr) 2002-10-02 2004-04-15 Dmi Biosciences, Inc. Diagnostic et controle de maladies
US20040086864A1 (en) 2002-10-22 2004-05-06 The Chinese University Of Hong Kong Novel classification methods for pleural effusions
GB0225360D0 (en) 2002-10-31 2002-12-11 Univ London Genetic markers
AU2002952993A0 (en) 2002-11-29 2002-12-12 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Therapeutic and diagnostic agents
CN100379882C (zh) 2003-01-17 2008-04-09 香港中文大学 作为妊娠相关病症的诊断标志物的循环mRNA
WO2004070388A1 (fr) 2003-02-04 2004-08-19 Evotec Neurosciences Gmbh Utilisation diagnostique et therapeutique de la proteine scn2b pour des maladies neurodegeneratives
US20080107600A1 (en) 2003-02-13 2008-05-08 Taiichi Katayama Gene Marker And Composition For Diagnosis And Treatment Of Neurological Disorders And Diseases And Use Of The Same
WO2004076639A2 (fr) 2003-02-26 2004-09-10 Wyeth Compositions et methodes destinees a diagnostiquer et traiter des maladies auto-immunes
CA2529759A1 (fr) 2003-06-20 2005-10-13 University Of Florida Biomarqueurs permettant de differencier des diabetes de types 1 et 2
DE10333406A1 (de) 2003-07-15 2005-02-10 Protagen Ag T-regulatorische-Zellen enthaltend Galectine zur Therapie und Diagnose von Erkrankungen
WO2005012907A1 (fr) 2003-08-01 2005-02-10 Renovar, Inc. Systemes et procedes pour caracteriser des maladies renales
WO2005023091A2 (fr) 2003-09-05 2005-03-17 The Trustees Of Boston University Procede de diagnostic prenatal non effractif
US7445886B2 (en) 2003-09-10 2008-11-04 Board Of Regents, The University Of Texas System Macrophage migration inhibitory factor as a marker for cardiovascular risk
CA2539535A1 (fr) 2003-10-03 2005-04-14 Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services Utilisation de cripto-1 en tant que biomarqueur pour maladie neurodegenerative et methode d'inhibition d'une maladie neurodegenerative
CA2541706C (fr) 2003-10-08 2014-02-18 The Trustees Of Boston University Methodes de diagnostic prenatal d'anomalies chromosomiques
DE60328193D1 (de) 2003-10-16 2009-08-13 Sequenom Inc Nicht invasiver Nachweis fötaler genetischer Merkmale
EP1685410A1 (fr) 2003-11-19 2006-08-02 EVOTEC Neurosciences GmbH Utilisation diagnostique et therapeutique du gene humain sgpl1 et d'une proteine contre les maladies neurodegeneratives
US20060094064A1 (en) 2003-11-19 2006-05-04 Sandip Ray Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids
CA2546461A1 (fr) 2003-11-19 2005-06-09 Satoris, Inc. Methodes et compositions pour le diagnostic, la stratification et la surveillance de la maladie d'alzheimer et d'autres troubles neurologiques dans des fluides corporels
WO2005072340A2 (fr) 2004-01-27 2005-08-11 Compugen Ltd. Nouveaux polynucleotides codant pour des polypeptides et leurs procedes d'utilisation
EP1711633A1 (fr) 2004-02-04 2006-10-18 EVOTEC Neurosciences GmbH Utilisation du gene kcne4 pour diagnostic et therapie, et proteine pour la maladie d'alzheimer
US20050266432A1 (en) 2004-02-26 2005-12-01 Illumina, Inc. Haplotype markers for diagnosing susceptibility to immunological conditions
EP1733231B1 (fr) 2004-04-05 2011-05-04 Université Bordeaux 2 Peptides et peptidomimetiques se liant a cd23
US20080051334A1 (en) 2004-04-16 2008-02-28 Evotec Neurosciences Gmbh Diagnostic and Therapeutic Use of Kcnc1 for Neurodegenerative Diseases
EP1740957B1 (fr) 2004-04-20 2014-03-12 SphingoTec GmbH Utilisation de precurseurs de tachykinines et/ou de fragments de celles-ci dans un diagnostic medical
US20090041862A1 (en) 2004-05-07 2009-02-12 Peter Robert Schofield Detecting disease association with aberrant glycogen synthase kinase 3beta expression
US20080038730A1 (en) 2004-05-10 2008-02-14 Heinz Von Der Kammer Diagnostic and Therapeutic Use of Kcnj6 for Alzheimer's Disease
WO2005114222A1 (fr) 2004-05-13 2005-12-01 Sphingo Tec Gmbh Utilisation de precurseurs des enkephalines et/ou de leurs fragments dans les diagnostics medicaux
WO2005111626A2 (fr) 2004-05-19 2005-11-24 Københavns Universitet Adam12, marqueur pour fonction cellulaire anormale
US7709194B2 (en) 2004-06-04 2010-05-04 The Chinese University Of Hong Kong Marker for prenatal diagnosis and monitoring
EP1797425A2 (fr) 2004-07-19 2007-06-20 University of Rochester Biomarqueurs de maladie neurodegenerative
EP1778874B1 (fr) 2004-07-30 2011-11-23 Adeza Biomedical Corporation Fibronectine oncofoetale en tant que marqueur de cancer du col utérin
WO2006020899A2 (fr) 2004-08-13 2006-02-23 Metrigenix Corporation Marqueurs pour la detection de maladies auto-immunes
US20070087376A1 (en) 2004-08-30 2007-04-19 Potashkin Judith A Splice variants of pre-mRNA transcripts as biomarkers in idiopathic neurodegenerative diseases
WO2006032126A1 (fr) 2004-09-24 2006-03-30 Syn X Pharma, Inc. Diagnostic et traitement du prediabete de type 1 au moyen de proteines neuronales
US7595159B2 (en) 2004-11-03 2009-09-29 The Brigham And Women's Hospital, Inc. Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
WO2006048778A1 (fr) 2004-11-08 2006-05-11 King's College London Marqueurs de la predisposition a des etats de dependance
US20060115855A1 (en) 2004-12-01 2006-06-01 Power3 Medical Products, Inc. FK506-binding protein 7 related protein as a biomarker for neurodegenerative disease
US20060115854A1 (en) 2004-12-01 2006-06-01 Power3 Medical Products, Inc. Acetyl-LDL receptor related proteins and peptides as a biomarker for neurodegenerative disease
GB0426859D0 (en) 2004-12-07 2005-01-12 Proteome Sciences Plc Diagnosis of neurodegenerative disorders
CA2590781A1 (fr) 2004-12-07 2006-06-15 Electrophoretics Limited Diagnostic de maladies neurodegeneratives
EP1838735A2 (fr) 2004-12-31 2007-10-03 Genentech, Inc. Polypeptides de liaison a la br3 et leurs utilisations
FR2880897B1 (fr) 2005-01-18 2010-12-17 Inst Nat Sante Rech Med Methode de detection, non invasive, prenatale, in vitro de l'etat sain normal, de l'etat de porteur sain ou de l'etat de porteur malade de la mucoviscidose
US7432107B2 (en) 2005-01-24 2008-10-07 Roche Diagnostics Operations, Inc. Cardiac hormones for assessing cardiovascular risk
US7572592B2 (en) 2005-01-31 2009-08-11 Glycominds Ltd Method for diagnosing multiple sclerosis
US20070141625A1 (en) 2005-02-03 2007-06-21 Santos Jose H Method for assessing risk of and predisposition to development of a pathology related to the presence of anti-epcr autoantibodies
EP2612928A3 (fr) 2005-03-18 2013-09-11 The Chinese University Of Hong Kong Marqueurs pour le diagnostic et la surveillance prénatale
JP5219516B2 (ja) 2005-03-18 2013-06-26 ザ チャイニーズ ユニバーシティー オブ ホンコン 染色体異数性の検出方法
WO2006102498A2 (fr) 2005-03-24 2006-09-28 Beth Israel Deaconess Medical Center Procedes de diagnostic de la trisomie foetale 13 ou d'un risque de trisomie foetale 13 pendant la grossesse
PT2146209E (pt) 2005-04-06 2011-12-30 Univ Antwerp Marcadores neurodegenerativos para a doença de alzheimer
NZ562436A (en) 2005-04-18 2010-01-29 Provost Fellows & Scholars Of Toll-like receptor 14 (TLR14) and use thereof
WO2006114661A1 (fr) 2005-04-26 2006-11-02 Dwek Raymond A Analyse de glycane a haut rendement pour diagnostiquer et surveiller l'arthrite rhumatoide et d'autres maladies auto-immunes
AU2006247134B2 (en) 2005-05-18 2012-05-10 Novartis Ag Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component
GB0512401D0 (en) 2005-06-17 2005-07-27 Randox Lab Ltd Method
GB2428240A (en) 2005-07-14 2007-01-24 Univ Gen Ve Diagnostic method for brain damage-related disorders
US20070148661A1 (en) 2005-07-19 2007-06-28 Duke University LSAMP Gene Associated With Cardiovascular Disease
US20070218469A1 (en) 2005-10-03 2007-09-20 Ruth Navon Novel mutations in hexosaminidase A
IL172297A (en) 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for the diagnosis of preeclampsia
AU2006302031A1 (en) 2005-10-11 2007-04-19 Tethys Bioscience, Inc. Diabetes-associated markers and methods of use thereof
US8652467B2 (en) 2005-10-14 2014-02-18 The Regents Of The University Of Michigan Dek protein compositions and methods of using the same
TW200726845A (en) 2006-01-02 2007-07-16 Nat Defense Medical Ct Biomarker molecular of renal illness and detecting method for the same
EP1808694A1 (fr) 2006-01-17 2007-07-18 Universitätsklinikum Freiburg Procédé de diagnostic d'une maladie polykystique des reins
FR2896588B1 (fr) 2006-01-20 2016-08-19 Univ D'angers Methode de diagnostic in vitro de reponse immunitaire autoimmune par detection d'anticorps diriges contre l'antigene pentraxine 3.
WO2007090126A2 (fr) 2006-01-30 2007-08-09 Invitrogen Corporation COMPOSITIONS et procedes pour detecter et quantifier des substances toxiques dans des etats pathologiques
US7459280B2 (en) 2006-02-27 2008-12-02 Picobella, Llc Methods for diagnosing and treating kidney cancer
WO2007098585A1 (fr) 2006-02-28 2007-09-07 Phenomenome Discoveries Inc. Méthodes permettant de diagnostiquer la démence et autres troubles neurologiques
US7488584B2 (en) 2006-03-24 2009-02-10 Picobella Methods for diagnosing and treating kidney and colorectal cancer
US20070224638A1 (en) 2006-03-27 2007-09-27 Institut Pasteur Secreted proteins as early markers and drug targets for autoimmunity, tumorigenesis and infections
GB0606776D0 (en) 2006-04-03 2006-05-10 Novartis Pharma Ag Predictive biomarkers for chronic allograft nephropathy
EP1847615A1 (fr) 2006-04-18 2007-10-24 Genoscreen Expression et polymorphisme du gène transcarbamylase d'ornithine (OTC) comme marqueurs diagnostiques de la maladie d'Alzheimer
US7662578B2 (en) 2006-04-21 2010-02-16 Children's Hospital Medical Center Method and kit for the early detection of impaired renal status
EP2021799B1 (fr) 2006-04-27 2011-07-20 Critical Care Diagnostics, Inc. Interleukine-33 (il-33) utilisée pour le diagnostic et le pronostic des maladies cardiovasculaires
JP5377289B2 (ja) 2006-05-01 2013-12-25 クリティカル ケア ダイアグノスティクス インコーポレイテッド 心血管疾患の診断方法
US7754428B2 (en) 2006-05-03 2010-07-13 The Chinese University Of Hong Kong Fetal methylation markers
US7901884B2 (en) 2006-05-03 2011-03-08 The Chinese University Of Hong Kong Markers for prenatal diagnosis and monitoring
WO2007131345A1 (fr) 2006-05-12 2007-11-22 The Hospital For Sick Children Facteur de risque génétique dans les gènes sod1 et sfrs15 dans la néphropathie, la cataracte diabétique, la maladie cardiovasculaire et la longévité
US8257933B2 (en) 2006-05-12 2012-09-04 Keio University Detection of inflammatory disease and composition for prevention or treatment of inflammatory disease
ES2497641T3 (es) 2006-05-17 2014-09-23 The Ludwig Institute For Cancer Research Dirección a la regulación de VEGF-B de transportadores de ácidos grasos para modular enfermedades humanas
WO2007139895A2 (fr) 2006-05-24 2007-12-06 Cellumen, Inc. Procédé de modélisation d'une maladie
US20080038269A1 (en) 2006-05-25 2008-02-14 Mount Sinai Hospital Methods for detecting and treating kidney disease
DE102006027818A1 (de) 2006-06-16 2007-12-20 B.R.A.H.M.S. Aktiengesellschaft In vitro Multiparameter-Bestimmungsverfahren zur Diagnose und Frühdiagnose von neurodegenerativen Erkrankungen
WO2008084331A2 (fr) 2006-06-21 2008-07-17 Hopitaux Universitaires De Geneve Biomarqeurs pour des troubles rénaux
WO2008003826A1 (fr) 2006-07-07 2008-01-10 Oy Jurilab Ltd Nouveaux gènes et marqueurs dans l'hypertension arterielle essentielle
KR100856375B1 (ko) 2006-07-18 2008-09-04 김현기 퇴행성 신경질환 진단용 마커
US7851172B2 (en) 2006-07-25 2010-12-14 University Of Kentucky Research Foundation Biomarkers of mild cognitive impairment and alzheimer's disease
US20080113358A1 (en) 2006-07-28 2008-05-15 Ravi Kapur Selection of cells using biomarkers
US20080026378A1 (en) 2006-07-28 2008-01-31 Gian Franco Bottazzo Prediction and prophylactic treatment of type 1 diabetes
ITTO20060614A1 (it) 2006-08-21 2008-02-22 Uni Degli Studi Del Piemonte "diagnosi differenziale per la sclerodermia"
US20080152589A1 (en) 2006-09-08 2008-06-26 Peter Schofield Diagnostics and Therapeutics of Neurological Disease
JP2010503840A (ja) 2006-09-14 2010-02-04 ゾラ バイオサイエンシズ オイ 自己免疫および１型糖尿病のリスクの早期予測ツールとしての生体流動の代謝体プロファイリング
EP1905841A1 (fr) 2006-09-25 2008-04-02 Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; Trex1 comme marqueur du lupus érythemateux
WO2008037449A2 (fr) 2006-09-26 2008-04-03 Proteosys Ag Utilisation d'au moins une isoforme du composant 1 de la membrane du récepteur de la progestérone (pgrmc1)
WO2008042012A1 (fr) 2006-10-05 2008-04-10 Rhode Island Hospital Compositions et procédés pour détecter et traiter une blessure rénale et une inflammation
WO2008043725A1 (fr) 2006-10-10 2008-04-17 Novartis Ag Biomarqueur utilisé dans des affections inflammatoires
US20100029007A1 (en) 2006-10-11 2010-02-04 Novaartis Ag Biomarker in Inflammatory Diseases
WO2008046509A1 (fr) 2006-10-16 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Protéine ltbp2 utilisée en tant que biomarqueur, cible thérapeutique et diagnostique
WO2008046510A1 (fr) 2006-10-16 2008-04-24 Bayer Healthcare Ag Fn1 utilisé comme biomarqueur, cible thérapeutique et diagnostique
WO2008046511A1 (fr) 2006-10-16 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Crtac utilisé comme biomarqueur, cible thérapeutique et diagnostique
EP2087359A1 (fr) 2006-10-16 2009-08-12 Bayer Schering Pharma AG Prss23 utilisée comme biomarqueur, cible thérapeutique et diagnostique
WO2008046160A1 (fr) 2006-10-20 2008-04-24 Newcastle Innovation Limited Méthode de détection de biomarqueurs associés à des états liés à la grossesse
CN101636175A (zh) 2006-11-01 2010-01-27 乔治梅森知识产权公司 用于神经病况的生物标记
EP2089712A4 (fr) 2006-11-22 2010-09-22 Life Technologies Corp Biomarqueurs de maladies auto-immunes
US20100169988A1 (en) 2006-12-06 2010-07-01 Bernhard Kohli Means and methods for isolating and determining novel targets for the treatment of neurodegenerative, neurological or neuropsychiatric disorders and compositions comprising the same
IL180095A0 (en) 2006-12-14 2007-05-15 Ohad Birk Method for antenatal estimation of down syndrome risk
WO2008082519A2 (fr) 2006-12-19 2008-07-10 The Trustees Of The University Of Pennsylvania RECHERCHE SYSTÉMATIQUE DE POLYMORPHISME(S) ASSOCIÉ(S) AU C1qRP DE CD93 POUR LE DIAGNOSTIC, LA PRÉVENTION ET LE TRAITEMENT DE MALADIES AUTO-IMMUNES
US8815519B2 (en) 2006-12-22 2014-08-26 Hvidovre Hospital Method for predicting cancer and other diseases
EP2155228B1 (fr) 2007-01-10 2014-04-02 Purdue Research Foundation Inhibiteurs polypeptidiques de la hsp27 kinase et leurs utilisations
WO2008085024A1 (fr) 2007-01-12 2008-07-17 Erasmus University Medical Center Rotterdam Identification et détection de peptides associés à des troubles spécifiques
US8058015B2 (en) 2007-01-22 2011-11-15 Medizinische Universität Innsbruck Markers for chronic kidney disease
AU2008213742A1 (en) 2007-02-08 2008-08-14 Powmri Limited Method of diagnosing a neurodegenerative disease
WO2008100596A2 (fr) 2007-02-15 2008-08-21 Burnham Institute For Medical Research Biomarqueurs de maladie neurodégénérative
DK2471954T3 (en) 2007-02-21 2016-09-12 Decode Genetics Ehf Susceptibility genetic variants associated with cardiovascular diseases
CA2718127A1 (fr) 2007-03-14 2008-09-18 Baylor Research Institute Expression genique dans des cellules sanguines mononucleaires peripheriques d'enfants diabetiques
JP2010524434A (ja) 2007-03-26 2010-07-22 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ Ｋｃｎｈ２の統合失調症関連アイソフォームおよび抗精神病薬の開発
EP1975252A1 (fr) 2007-03-29 2008-10-01 INSERM (Institut National de la Santé et de la Recherche Medicale) Procédés pour le pronostic ou le diagnostic d'une maladie thyroïdienne
US20120052592A9 (en) 2007-03-30 2012-03-01 Nano Solution, Inc., Method for determining prognosis of acute central nervous system disorder
PL390236A1 (pl) 2007-04-12 2010-07-05 Apitope International Nvapitope International Nv Biomarkery stwardnienia rozsianego
GB0707933D0 (en) 2007-04-24 2007-05-30 Apitope Technology Bristol Ltd Disease markers
GB0708075D0 (en) 2007-04-26 2007-06-06 Univ Nottingham Nethods
WO2008137586A1 (fr) 2007-05-01 2008-11-13 University Of Miami Biomarqueurs transcriptomiques pour évaluation de risque individuel de nouvelle survenue d'insuffisance cardiaque
AU2008247395A1 (en) 2007-05-03 2008-11-13 Medimmune, Llc Auto-antibody markers of autoimmune disease
WO2008147938A2 (fr) 2007-05-24 2008-12-04 Centocor, Inc. Wnt5a utilise en tant que marqueur des maladies inflammatoires
EP2160478B1 (fr) 2007-06-06 2014-08-27 Siemens Healthcare Diagnostics Inc. Diagnostics prédictifs pour maladie rénale
US20090142792A1 (en) 2007-06-21 2009-06-04 Robinson William H Biomarkers for the diagnosis of autoimmune disease
ITRM20070351A1 (it) 2007-06-22 2008-12-23 Istituto Naz Per Le Malattie I Gene codificante la proteina ambra 1 avente attivita' regolatoria dell autofagia e dello sviluppo del sistema nervoso centrale
WO2009000520A1 (fr) 2007-06-25 2008-12-31 Universität Duisburg-Essen Procédé de criblage pour des marqueurs polymorphes dans le gène htra1 dans des troubles neurodégénératifs
US8227201B2 (en) 2007-06-27 2012-07-24 Board Of Trustees Of The Leland Stanford Junior University BETA2-microglobulin and C reactive protein (CRP) as biomarkers for peripheral artery disease
FR2918329B1 (fr) 2007-07-06 2009-10-02 Renault Sas Ecope de refroidissement pour vehicule automobile
EP2173438A2 (fr) 2007-07-13 2010-04-14 Genentech, Inc. Traitement et diagnostics du cancer, de troubles inflammatoires et de troubles auto-immuns
BRPI0815095B1 (pt) 2007-07-17 2021-04-13 Metabolon, Inc Método de classificação de um indivíduo de acordo com a tolerância à glicose predita em tolerância à glicose normal (ngt), tolerância à glicose de jejum prejudicada (ifg), ou tolerância à glicose prejudicada (igt), para diabetes tipo 2, método de determinação da suscetibilidade de um indivíduo a diabetes tipo 2 e método de monitoramento da progressão ou regressão do pré- diabetes em um indivíduo
KR20100063052A (ko) 2007-08-02 2010-06-10 아이에스에스 이뮨 시스템 스티뮬레이션 에이비 염증성 장 질환의 진단, 단계 구분 및 모니터링 방법
US20090275046A1 (en) 2007-08-29 2009-11-05 Power3 Medical Products, Inc. Complement factor H protein as a biomarker of Parkinson's disease
WO2009032722A1 (fr) 2007-08-29 2009-03-12 The Cleveland Clinic Foundation Protéines carbamylées et risque de maladie cardiovasculaire
US8748100B2 (en) 2007-08-30 2014-06-10 The Chinese University Of Hong Kong Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences
GB0717637D0 (en) 2007-09-10 2007-10-17 Univ Leiden Future cardiac event biomarkers
US8062852B2 (en) 2007-10-01 2011-11-22 The Children's Hospital And Regional Medical Center Detection and treatment of autoimmune disorders
ITUD20070183A1 (it) 2007-10-01 2009-04-02 Univ Degli Studi Udine Metodo diagnostico e prognostico per la diagnosi e la prognosi della linfoproliferazione nelle malattie autoimmuni
GB0720113D0 (en) * 2007-10-15 2007-11-28 Cambridge Cancer Diagnostics L Diagnostic, prognostic and predictive testing for cancer
EP2212693B1 (fr) 2007-10-22 2015-04-22 The Regents of The University of California Biomarqueurs pour un diagnostic prénatal de cytomégalovirus congénital
FI20070795A0 (fi) 2007-10-24 2007-10-24 Faron Pharmaceuticals Oy Uusi biomarkkeri sairauksien kehittämisen tarkkailuun ja terapioiden tehon arviointiin
JP2011501177A (ja) 2007-10-26 2011-01-06 ビオヒット・ユルキネン・オサケユキテュア 自己免疫疾患および萎縮性胃炎と関連する胃癌を診断するための方法および製品
WO2009059259A2 (fr) 2007-10-31 2009-05-07 Children's Hospital Medical Center Détection de l'aggravation d'une pathologie rénale chez des sujets atteints de lupus érythémateux disséminé
WO2009058168A1 (fr) 2007-11-04 2009-05-07 Prediction Sciences Llc Fibronectine cellulaire en tant que marqueur de diagnostic dans une maladie cardiovasculaire et ses procédés d'utilisation
EP2209916B1 (fr) 2007-11-08 2011-12-21 Novartis AG Signatures d'expression génique pour une néphropathie d'allogreffe chronique/sclérosante
US8008013B2 (en) 2007-11-16 2011-08-30 Oklahoma Medical Research Foundation Predicting and diagnosing patients with autoimmune disease
US20100255485A1 (en) 2007-11-28 2010-10-07 Pico Caroni Biomarkers for the onset of neurodegenerative diseases
US8506933B2 (en) 2007-11-30 2013-08-13 Msdx, Inc. Methods of detecting a neurological condition via analysis of circulating phagocytes
WO2009074331A2 (fr) 2007-12-11 2009-06-18 Julius-Maximilians-Universität Würzburg Test diagnostique precoce et differentiel de la maladies d'alzheimer
WO2009075566A1 (fr) 2007-12-12 2009-06-18 Erasmus University Medical Center Rotterdam Biomarqueurs pour maladie cardiovasculaire
EP2075343A1 (fr) 2007-12-21 2009-07-01 Gert Mayer Procédé pour diagnostiquer une maladie progressive
WO2009083950A2 (fr) 2007-12-27 2009-07-09 Compugen Ltd. Biomarqueurs pour prévoir l'apparition d'une lésion rénale
BRPI0906858B8 (pt) * 2008-01-18 2021-07-27 Harvard College métodos in vitro para detectar a presença de uma célula de câncer em um indivíduo e para identificar uma assinatura específica de tumor em um indivíduo tendo câncer.
JP2011510308A (ja) 2008-01-23 2011-03-31 リグスホスピタル バイオマーカーｙｋｌ−４０のレベルの測定により見出される生存予後に基く心血管疾患を患う個体の分類
US20090299155A1 (en) 2008-01-30 2009-12-03 Dexcom, Inc. Continuous cardiac marker sensor system
AU2009212463A1 (en) 2008-02-04 2009-08-13 Banyan Biomarkers, Inc. Process to diagnose or treat brain injury
CA2714410A1 (fr) 2008-02-08 2009-08-13 Medimmune, Llc Marqueurs de troubles et leur utilisation
US20090239242A1 (en) 2008-03-18 2009-09-24 Biotrin Intellectual Properties Limited Method for the early identification and prediction of kidney injury
AU2008255192A1 (en) 2008-03-22 2009-10-08 Newcastle Innovation Limited Detection of a biomarker of aberrant cells of neuroectodermal origin in a body fluid
GB0809069D0 (en) 2008-05-19 2008-06-25 Univ Leuven Kath Gene signatures
WO2009122387A1 (fr) 2008-04-04 2009-10-08 Biotrin Group Ltd. Procédé de détection et de prédiction de maladie rénale associée à l’obésité
EP2107377A1 (fr) 2008-04-04 2009-10-07 BRAHMS Aktiengesellschaft Niveaux pro-endothéline 1 pour la prédiction d'un risque d'événements tachyarrhytmiques
AU2009237710A1 (en) 2008-04-15 2009-10-22 Rainer Oberbauer Markers of acute kidney failure
US8030097B2 (en) 2008-04-30 2011-10-04 Versitech Limited and R & C Biogenius Limited Lipocalin-2 as a prognostic and diagnostic marker for heart and stroke risks
WO2010005750A2 (fr) 2008-06-16 2010-01-14 The Regents Of The University Of California Marqueurs pronostics et cibles thérapeutiques potentiels pour troubles neurologiques
US20100167937A1 (en) 2008-07-08 2010-07-01 Power3 Medical Products, Inc. Multiple forms of Alzheimer's disease based on differences in concentrations of protein biomarkers in blood serum
WO2010011506A2 (fr) 2008-07-23 2010-01-28 The Washington University Facteurs de risque et cible thérapeutique pour des troubles neurodégénératifs
WO2010012306A1 (fr) 2008-07-31 2010-02-04 Queen Mary And Westfield College, University Of London Biomarqueurs pour rein sain
NO2324360T3 (fr) 2008-08-11 2018-06-30
ES2341419B1 (es) 2008-08-14 2011-05-03 Hospital Clinic I Provincial De Barcelona Wnt1 como biomarcador de daño renal.
WO2010022210A2 (fr) 2008-08-21 2010-02-25 Pxbiosciences Llc Diagnostic et surveillance de l’insuffisance rénale au moyen de biomarqueurs peptidiques
EP2813848A3 (fr) 2008-08-29 2015-03-11 Astute Medical, Inc. Procédés et compositions pour le diagnostic et le pronostic de lésion rénale et d'insuffisance rénale
EP2161577A1 (fr) * 2008-09-01 2010-03-10 Atlas Antibodies AB Protéine ANLN
BRPI0913687A2 (pt) 2008-09-30 2015-10-13 Genentech Inc marcadores biológicos preditivos da resposta da artrite reumatóide aos antagonistas da linfotoxina
US20100124756A1 (en) 2008-10-10 2010-05-20 Sandip Ray Collection of biomarkers for diagnosis and monitoring of alzheimer's disease in body fluids
GB0818650D0 (en) 2008-10-10 2008-11-19 Uni I Oslo Methods
EP2347260A4 (fr) 2008-10-21 2012-09-26 Astute Medical Inc Procédés et compositions pour le diagnostic et le pronostic de lésion rénale et d'insuffisance rénale
CN102246035B (zh) 2008-10-21 2014-10-22 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
KR101051435B1 (ko) * 2008-10-22 2011-07-22 한국생명공학연구원 대장암 관련 마커를 이용한 대장암 진단 키트 및 이를 이용한 대장암 진단 방법
EP2180322A1 (fr) 2008-10-22 2010-04-28 BRAHMS Aktiengesellschaft Biomarqueurs de pronostic pour la progression d'une maladie de reins chroniques primaires
EP2337864B1 (fr) 2008-10-24 2014-11-26 Vereniging voor christelijk hoger onderwijs, Wetenschappelijk onderzoek en patiëntenzorg Biomarqueurs pour prédire le développement de maladies auto-immunes chroniques
WO2010048497A1 (fr) 2008-10-24 2010-04-29 Genizon Biosciences Inc. Profil génétique des marqueurs associés à la maladie d'alzheimer
EP2352502A4 (fr) 2008-11-06 2012-12-26 Univ Miami Protéolyse limitée de la cd2ap et évolution d'une maladie rénale
EP2364368B1 (fr) 2008-11-07 2014-01-15 Sequenta, Inc. Procédés de surveillance de maladies par analyse de séquence
AU2009313189B2 (en) 2008-11-10 2014-10-23 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010056757A1 (fr) 2008-11-11 2010-05-20 Entelos, Inc. Biomarqueurs pour évaluer le potentiel athérosclérotique
WO2010059242A2 (fr) 2008-11-21 2010-05-27 The Johns Hopkins University Compositions diagnostiques de maladie neurodégénérative et procédés d'utilisation
US20110229915A1 (en) 2008-11-22 2011-09-22 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
IT1392551B1 (it) 2008-11-25 2012-03-09 Bioindustry Park Del Canavese S P A Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica
US20120094315A1 (en) 2008-12-09 2012-04-19 Stephanie Fryar-Williams Biomarkers for the diagnosis and/or prediction of susceptibility to mental and neurodegenerative disorders
US9791452B2 (en) 2008-12-10 2017-10-17 Joslin Diabetes Center, Inc. Methods of diagnosing and predicting renal disease

Also Published As

Publication number Publication date
SG187159A1 (en) 2013-02-28
AU2017201440B2 (en) 2019-06-20
US20220298582A1 (en) 2022-09-22
EP2596132A2 (fr) 2013-05-29
JP2021074011A (ja) 2021-05-20
CA2806291C (fr) 2023-08-29
JP2019068804A (ja) 2019-05-09
CA2806291A1 (fr) 2012-01-26
US20150299810A1 (en) 2015-10-22
US20220298583A1 (en) 2022-09-22
US20190085402A1 (en) 2019-03-21
CN103119179A (zh) 2013-05-22
JP2013538565A (ja) 2013-10-17
EP4303584A2 (fr) 2024-01-10
JP2017060479A (ja) 2017-03-30
AU2011280996B2 (en) 2017-03-30
MX361944B (es) 2018-12-19
EA201390150A1 (ru) 2013-09-30
CN110846405A (zh) 2020-02-28
US20120053073A1 (en) 2012-03-01
AU2011280996A1 (en) 2013-02-28
BR112013001754A2 (pt) 2016-05-31
EP4303584A3 (fr) 2024-04-03
MX2013000916A (es) 2013-07-05
KR20130041961A (ko) 2013-04-25
WO2012012693A2 (fr) 2012-01-26
AU2017201440A1 (en) 2017-03-16
JP2023101574A (ja) 2023-07-21
WO2012012693A3 (fr) 2012-06-14
EP2596132A4 (fr) 2013-12-18

Similar Documents

Publication Publication Date Title
IL257739A (en) A method for detecting signatures of disease or conditions in body fluids
SG10201505723UA (en) Methods for detecting signatures of disease or conditions in bodily fluids
HK1206065A1 (en) Compositions and methods for analyte detection
ZA201300723B (en) Non-reusable collection device for bodily fluids
IL224016B (en) Apparatus for disease detection
ZA201401183B (en) Fluid level sensor and related methods
HK1200037A1 (en) Non-invasive methods of detecting target molecules
EP2539019A4 (fr) Détection d'effets de stimulation simultanés
EP2585833A4 (fr) Procédés de détection de cancer
EP2596117A4 (fr) Procédés de détection de maladies ou d'états associés au rein
EP2625522A4 (fr) Dispositifs microscopiques destinés à détecter des maladies
HK1204016A1 (en) Methods and kits for detecting subjects at risk of having cancer
HK1185245A1 (zh) 用於檢測低血糖症症狀的改進的系統
GB201004923D0 (en) Compact method for medical detection
EP2693953A4 (fr) Système et méthode de détection médicale à multimodalité
ZA201404463B (en) Detecting analytes
EP2721404A4 (fr) Diagnostic et pronostic de lésion rénale et d'insuffisance rénale
ZA201401830B (en) Dynamic surgical fluid sensing
AP2014007563A0 (en) Biosensor for point-of-care diagnostic and on-sitemeasurements
EP2451966A4 (fr) Procédés de détection précoce de troubles hématologiques
EP2614160A4 (fr) Détection des régions d'interaction de l'arn au sein de l'adn
GB0921712D0 (en) Methods of detecting DNA damage
EP2578699A4 (fr) Procédés de détection du risque d'obésité et du risque de déclenchement de diabète
EP2559970A4 (fr) Capteur de déplacement et procédé de détection de déplacement
EP2587997A4 (fr) Détermination d'indicateur de tissu