SE453492C - Förfarande för framställning av D-2-(6-metoxi-2-naftyl)- propionsyra - Google Patents

Förfarande för framställning av D-2-(6-metoxi-2-naftyl)- propionsyra

Info

Publication number
SE453492C
SE453492C SE8202050A SE8202050A SE453492C SE 453492 C SE453492 C SE 453492C SE 8202050 A SE8202050 A SE 8202050A SE 8202050 A SE8202050 A SE 8202050A SE 453492 C SE453492 C SE 453492C
Authority
SE
Sweden
Prior art keywords
methoxy
naphthyl
propionic acid
bromo
hydrogenation system
Prior art date
Application number
SE8202050A
Other languages
English (en)
Swedish (sv)
Other versions
SE8202050L (sv
SE453492B (sv
Inventor
V Cannata
G Tamerlani
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11106122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE453492(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Publication of SE8202050L publication Critical patent/SE8202050L/xx
Publication of SE453492B publication Critical patent/SE453492B/sv
Publication of SE453492C publication Critical patent/SE453492C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8202050A 1981-04-01 1982-03-31 Förfarande för framställning av D-2-(6-metoxi-2-naftyl)- propionsyra SE453492C (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Publications (3)

Publication Number Publication Date
SE8202050L SE8202050L (sv) 1982-10-02
SE453492B SE453492B (sv) 1988-02-08
SE453492C true SE453492C (sv) 1994-09-15

Family

ID=11106122

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8202050A SE453492C (sv) 1981-04-01 1982-03-31 Förfarande för framställning av D-2-(6-metoxi-2-naftyl)- propionsyra
SE8501744A SE466199B (sv) 1981-04-01 1985-04-09 N-metyl-d-glukaminsaltet av d-2-(5-bromo-6-metoxi-2-naftyl)-propionsyra

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8501744A SE466199B (sv) 1981-04-01 1985-04-09 N-metyl-d-glukaminsaltet av d-2-(5-bromo-6-metoxi-2-naftyl)-propionsyra

Country Status (26)

Country Link
US (1) US4423244A (fi)
JP (1) JPS57176925A (fi)
KR (1) KR860001547B1 (fi)
AR (1) AR230614A1 (fi)
AT (1) AT390253B (fi)
BE (1) BE892689A (fi)
CA (1) CA1190939A (fi)
CH (1) CH651289A5 (fi)
DE (1) DE3212170A1 (fi)
DK (2) DK157076C (fi)
ES (1) ES8302622A1 (fi)
FI (1) FI78455C (fi)
FR (1) FR2504918B1 (fi)
GB (1) GB2098981B (fi)
GR (1) GR76062B (fi)
HU (1) HU186852B (fi)
IE (1) IE52378B1 (fi)
IL (1) IL65298A (fi)
IT (1) IT1168387B (fi)
LU (1) LU84044A1 (fi)
NL (1) NL8201307A (fi)
NO (1) NO157733B (fi)
PT (1) PT74677B (fi)
SE (2) SE453492C (fi)
YU (1) YU42606B (fi)
ZA (1) ZA822145B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS262412B2 (en) * 1982-05-27 1989-03-14 Syntex Pharma Int Process for preparing d-2-/6-methoxy-2-naphthyl/propionic acid
FI831820L (fi) * 1982-05-27 1983-11-28 Syntex Pharma Int Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
IT1174084B (it) * 1984-05-10 1987-07-01 Blaschim Spa Procentimento per preparare il naproxen
US4814497A (en) * 1986-05-12 1989-03-21 Ethyl Corporation Dehalogenation process
IT1238008B (it) * 1990-02-08 1993-06-21 Alfa Wassermann Spa Procedimento per la debromurazione di 2-sostituiti-5-bromo- 6-metossinaftaleni
FR2686877B1 (fr) * 1992-01-31 1995-03-24 Hoechst France Procede de preparation de l'acide orthohydroxyphenylacetique.
JPH0646907U (ja) * 1992-12-10 1994-06-28 リョービ株式会社 すべり勾配面加工用治具
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
CA936171A (en) * 1970-09-09 1973-10-30 Syntex Corporation Process for preparing 2-(6-methoxy-2-naphthyl) propionic acid and 2-(6-methoxy-2-naphthyl)-1-propanol
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Also Published As

Publication number Publication date
YU72082A (en) 1985-03-20
FI821121A0 (fi) 1982-03-31
IT8103385A0 (it) 1981-04-01
NL8201307A (nl) 1982-11-01
IL65298A0 (en) 1982-05-31
KR830008973A (ko) 1983-12-16
SE8501744D0 (sv) 1985-04-09
SE8202050L (sv) 1982-10-02
AT390253B (de) 1990-04-10
ZA822145B (en) 1983-02-23
IL65298A (en) 1985-02-28
JPS57176925A (en) 1982-10-30
US4423244B1 (fi) 1987-07-28
KR860001547B1 (ko) 1986-10-04
CH651289A5 (de) 1985-09-13
FR2504918A1 (fr) 1982-11-05
AR230614A1 (es) 1984-05-31
ATA127082A (de) 1989-09-15
ES510931A0 (es) 1983-02-01
DK147482A (da) 1982-10-02
BE892689A (fr) 1982-09-30
SE453492B (sv) 1988-02-08
CA1190939A (en) 1985-07-23
DK157076B (da) 1989-11-06
FI821121L (fi) 1982-10-02
GR76062B (fi) 1984-08-03
ES8302622A1 (es) 1983-02-01
PT74677A (en) 1982-04-01
NO821088L (no) 1982-10-04
US4423244A (en) 1983-12-27
YU42606B (en) 1988-10-31
DK157076C (da) 1990-04-09
LU84044A1 (fr) 1983-02-22
SE8501744L (sv) 1985-04-09
NO157733B (no) 1988-02-01
SE466199B (sv) 1992-01-13
DK256589D0 (da) 1989-05-26
DE3212170C2 (fi) 1989-03-02
DK256589A (da) 1989-05-26
FR2504918B1 (fr) 1985-06-14
GB2098981A (en) 1982-12-01
HU186852B (en) 1985-10-28
FI78455C (fi) 1989-08-10
IT1168387B (it) 1987-05-20
FI78455B (fi) 1989-04-28
IE52378B1 (en) 1987-09-30
IE820770L (en) 1982-10-01
PT74677B (en) 1983-10-31
JPH0231704B2 (fi) 1990-07-16
GB2098981B (en) 1984-10-24
DE3212170A1 (de) 1982-10-21

Similar Documents

Publication Publication Date Title
SE453492C (sv) Förfarande för framställning av D-2-(6-metoxi-2-naftyl)- propionsyra
EP0095901B1 (en) Process for the preparation of (d) 2-(d-methoxy-2-naphthyl) propionic acid and pharmaceutically acceptable salts thereof and new intermediates therefor
EP0204911B1 (en) A new process for the optical resolution of racemic mixtures of alpha-naphthylpropionic acids
FI83073C (fi) Nytt foerfarande foer foerverkligande av optisk resolution av racemiska blandningar av -naftylpropionsyror.
US4005088A (en) Process for the chemical separation of racemic modifications of α-aminocarboxylic acid derivatives, and cinchonidine salt intermediates
US4520205A (en) Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid
EP0590685B1 (en) Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative
JPH05286889A (ja) アリール酢酸及びそれらのアルカリ金属塩の製造方法
WO1990008126A1 (en) Resolution process
JPH10204020A (ja) クロロ−ベンゾイルクロリド類の製造方法
WO1991003453A1 (en) Optically active 2-(alkyl-substituted phenyl)-propionic acid derivative and optical resolution of (±)-1-methyl-3-phenylpropylamine
JP3544694B2 (ja) Ｎ−ｔｅｒｔ−ブチル−２−ピペラジンカルボキサミド類の製造法
JP3234838B2 (ja) ２，４，５−トリフルオロ−３−ヒドロキシ安息香酸の製造方法
JPH0656736A (ja) ビス（２−ハロゲノ−４，５−ジフルオロ）ベンゾフェノン、及びそれを経る２−ハロゲノ−４，５−ジフルオロ安息香酸の新規な製造方法
JPH0215050A (ja) 光学活性（ｓ）−（−）−３−アルキルアミノ−１−アリールオキシプロパン−２−オールの製造法
JPS61112067A (ja) ３‐メチルフラボン‐８‐カルボン酸誘導体の製造法
JPS582938B2 (ja) ヒドロキシカルボスチリル誘導体の製造法
JP2001122823A (ja) ５−ブロモ−イソフタル酸ジアルキル化合物の製造方法
JP2001048845A (ja) 光学活性１−フェニル−２−（ｐ−置換フェニル）エチルアミン類の製造方法
JPH08113554A (ja) ２−インダニルメチルアミンの製造法並びにｎ−ベンジル−ｎ−（２−インダニルメチル）アミン及びその製造法
JP2000007619A (ja) ベンゾシクロヘプテン誘導体
JPH083108A (ja) ２−アルコキシ−６−アミノ安息香酸類の製造方法
CS262412B2 (en) Process for preparing d-2-/6-methoxy-2-naphthyl/propionic acid
JPH0745418B2 (ja) １，４，５，８―テトラメチルナフタレンの製造方法

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8202050-4

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8202050-4

Format of ref document f/p: F