IT1168387B - Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico - Google Patents

Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Info

Publication number
IT1168387B
IT1168387B IT03385/81A IT338581A IT1168387B IT 1168387 B IT1168387 B IT 1168387B IT 03385/81 A IT03385/81 A IT 03385/81A IT 338581 A IT338581 A IT 338581A IT 1168387 B IT1168387 B IT 1168387B
Authority
IT
Italy
Prior art keywords
naftil
methoxy
procedure
preparation
propionic acid
Prior art date
Application number
IT03385/81A
Other languages
English (en)
Other versions
IT8103385A0 (it
Inventor
Vincenzo Cannata
Giancarlo Tamerlani
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11106122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1168387(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Priority to IT03385/81A priority Critical patent/IT1168387B/it
Publication of IT8103385A0 publication Critical patent/IT8103385A0/it
Priority to IL65298A priority patent/IL65298A/xx
Priority to ZA822145A priority patent/ZA822145B/xx
Priority to US06/362,679 priority patent/US4423244A/en
Priority to KR8201353A priority patent/KR860001547B1/ko
Priority to LU84044A priority patent/LU84044A1/fr
Priority to PT74677A priority patent/PT74677B/pt
Priority to NL8201307A priority patent/NL8201307A/nl
Priority to GR67765A priority patent/GR76062B/el
Priority to BE2/59651A priority patent/BE892689A/fr
Priority to ES510931A priority patent/ES8302622A1/es
Priority to NO821088A priority patent/NO157733B/no
Priority to DK147482A priority patent/DK157076C/da
Priority to SE8202050A priority patent/SE453492C/sv
Priority to AR288954A priority patent/AR230614A1/es
Priority to FR8205530A priority patent/FR2504918B1/fr
Priority to CH1987/82A priority patent/CH651289A5/de
Priority to FI821121A priority patent/FI78455C/fi
Priority to YU720/82A priority patent/YU42606B/xx
Priority to HU82994A priority patent/HU186852B/hu
Priority to SI8210720A priority patent/SI8210720A8/sl
Priority to AT0127082A priority patent/AT390253B/de
Priority to IE770/82A priority patent/IE52378B1/en
Priority to JP57054723A priority patent/JPS57176925A/ja
Priority to CA000400096A priority patent/CA1190939A/en
Priority to GB8209661A priority patent/GB2098981B/en
Priority to DE19823212170 priority patent/DE3212170A1/de
Priority to SE8501744A priority patent/SE466199B/sv
Publication of IT1168387B publication Critical patent/IT1168387B/it
Application granted granted Critical
Priority to DK256589A priority patent/DK256589A/da
Priority to HR940598A priority patent/HRP940598B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT03385/81A 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico IT1168387B (it)

Priority Applications (30)

Application Number Priority Date Filing Date Title
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
IL65298A IL65298A (en) 1981-04-01 1982-03-21 Process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid
KR8201353A KR860001547B1 (ko) 1981-04-01 1982-03-29 d-2-(6-메톡시-2-나프틸)-프로피온산의 제조방법
US06/362,679 US4423244A (en) 1981-04-01 1982-03-29 Process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid
ZA822145A ZA822145B (en) 1981-04-01 1982-03-29 A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid
LU84044A LU84044A1 (fr) 1981-04-01 1982-03-30 Nouveau procede de preparation de l'acide d-2(6-metoxy-2-naphtyl)propionique
PT74677A PT74677B (en) 1981-04-01 1982-03-30 A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid
NL8201307A NL8201307A (nl) 1981-04-01 1982-03-30 Nieuwe werkwijze voor de bereiding van d-2-(6-methoxy-2-naftyl)-propionzuur.
GR67765A GR76062B (it) 1981-04-01 1982-03-30
BE2/59651A BE892689A (fr) 1981-04-01 1982-03-30 Nouveau procede de preparation de l'acide d-2(6-methoxy-2-naphtyl)-propionique
ES510931A ES8302622A1 (es) 1981-04-01 1982-03-30 "un procedimiento para la preparacion del acido d-2-(6-metoxi-2-naftil)-propionico".
CA000400096A CA1190939A (en) 1981-04-01 1982-03-31 Process for the preparation of the d-2-(6-methoxy-2- naphthyl)-propionic acid
SE8202050A SE453492C (sv) 1981-04-01 1982-03-31 Förfarande för framställning av D-2-(6-metoxi-2-naftyl)- propionsyra
IE770/82A IE52378B1 (en) 1981-04-01 1982-03-31 A new process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid
NO821088A NO157733B (no) 1981-04-01 1982-03-31 FremgangsmŸte for fremstilling av d-2-(6-metoksy-2-naftyl)-propionsyre.
AR288954A AR230614A1 (es) 1981-04-01 1982-03-31 Procedimiento para preparar el acido d-2(6-metoxi-2-naftil)-propionico
FR8205530A FR2504918B1 (fr) 1981-04-01 1982-03-31 Procede de preparation de l'acide d-2-(6-methoxy-2-naphtyl)-propionique
CH1987/82A CH651289A5 (de) 1981-04-01 1982-03-31 Verfahren zur herstellung der d-2-(6-methoxy-2-naphthyl)-propionsaeure.
FI821121A FI78455C (fi) 1981-04-01 1982-03-31 Nytt foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra.
YU720/82A YU42606B (en) 1981-04-01 1982-03-31 Process for preparing d-2-(6-methoxy-2-naphthyl)-propinic acid
HU82994A HU186852B (en) 1981-04-01 1982-03-31 Process for producing d-2-bracket-6-methoxy-2-naphtyl-bracket closed-proponic acid
SI8210720A SI8210720A8 (sl) 1981-04-01 1982-03-31 Nov postopek za pripravo d-2-(6-metoksi-2-naftil)-propionske kisline
AT0127082A AT390253B (de) 1981-04-01 1982-03-31 Verfahren zur herstellung der d-2-(6-methoxy-2naphthyl)-propionsaeure
DK147482A DK157076C (da) 1981-04-01 1982-03-31 Fremgangsmaade til fremstilling af d-2-(6-methoxy-2-naphthyl)-propionsyre
JP57054723A JPS57176925A (en) 1981-04-01 1982-03-31 Manufacture of d-2-(6-methoxy-2-naphthyl)propionic acid
DE19823212170 DE3212170A1 (de) 1981-04-01 1982-04-01 Verfahren zur herstellung der d-2-(6-methoxy-2-naphthyl)- propionsaeure
GB8209661A GB2098981B (en) 1981-04-01 1982-04-01 Preparataion of d-2-(6-methoxy-2-naphthyl) propionic acid
SE8501744A SE466199B (sv) 1981-04-01 1985-04-09 N-metyl-d-glukaminsaltet av d-2-(5-bromo-6-metoxi-2-naftyl)-propionsyra
DK256589A DK256589A (da) 1981-04-01 1989-05-26 N-methyl-d-glucaminsalt af d-2-(5-brom-6-methoxy-2-naphtyl)propionsyre
HR940598A HRP940598B1 (en) 1981-04-01 1994-09-26 New process for the preparation of d-2-(6-methoxy-2-naphthyl)-propionic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Publications (2)

Publication Number Publication Date
IT8103385A0 IT8103385A0 (it) 1981-04-01
IT1168387B true IT1168387B (it) 1987-05-20

Family

ID=11106122

Family Applications (1)

Application Number Title Priority Date Filing Date
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Country Status (26)

Country Link
US (1) US4423244A (it)
JP (1) JPS57176925A (it)
KR (1) KR860001547B1 (it)
AR (1) AR230614A1 (it)
AT (1) AT390253B (it)
BE (1) BE892689A (it)
CA (1) CA1190939A (it)
CH (1) CH651289A5 (it)
DE (1) DE3212170A1 (it)
DK (2) DK157076C (it)
ES (1) ES8302622A1 (it)
FI (1) FI78455C (it)
FR (1) FR2504918B1 (it)
GB (1) GB2098981B (it)
GR (1) GR76062B (it)
HU (1) HU186852B (it)
IE (1) IE52378B1 (it)
IL (1) IL65298A (it)
IT (1) IT1168387B (it)
LU (1) LU84044A1 (it)
NL (1) NL8201307A (it)
NO (1) NO157733B (it)
PT (1) PT74677B (it)
SE (2) SE453492C (it)
YU (1) YU42606B (it)
ZA (1) ZA822145B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS262412B2 (en) * 1982-05-27 1989-03-14 Syntex Pharma Int Process for preparing d-2-/6-methoxy-2-naphthyl/propionic acid
FI831820L (fi) * 1982-05-27 1983-11-28 Syntex Pharma Int Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
IT1174084B (it) * 1984-05-10 1987-07-01 Blaschim Spa Procentimento per preparare il naproxen
US4814497A (en) * 1986-05-12 1989-03-21 Ethyl Corporation Dehalogenation process
IT1238008B (it) * 1990-02-08 1993-06-21 Alfa Wassermann Spa Procedimento per la debromurazione di 2-sostituiti-5-bromo- 6-metossinaftaleni
FR2686877B1 (fr) * 1992-01-31 1995-03-24 Hoechst France Procede de preparation de l'acide orthohydroxyphenylacetique.
JPH0646907U (ja) * 1992-12-10 1994-06-28 リョービ株式会社 すべり勾配面加工用治具
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
CA936171A (en) * 1970-09-09 1973-10-30 Syntex Corporation Process for preparing 2-(6-methoxy-2-naphthyl) propionic acid and 2-(6-methoxy-2-naphthyl)-1-propanol
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Also Published As

Publication number Publication date
YU72082A (en) 1985-03-20
FI821121A0 (fi) 1982-03-31
IT8103385A0 (it) 1981-04-01
NL8201307A (nl) 1982-11-01
IL65298A0 (en) 1982-05-31
KR830008973A (ko) 1983-12-16
SE8501744D0 (sv) 1985-04-09
SE8202050L (sv) 1982-10-02
AT390253B (de) 1990-04-10
ZA822145B (en) 1983-02-23
IL65298A (en) 1985-02-28
JPS57176925A (en) 1982-10-30
US4423244B1 (it) 1987-07-28
SE453492C (sv) 1994-09-15
KR860001547B1 (ko) 1986-10-04
CH651289A5 (de) 1985-09-13
FR2504918A1 (fr) 1982-11-05
AR230614A1 (es) 1984-05-31
ATA127082A (de) 1989-09-15
ES510931A0 (es) 1983-02-01
DK147482A (da) 1982-10-02
BE892689A (fr) 1982-09-30
SE453492B (sv) 1988-02-08
CA1190939A (en) 1985-07-23
DK157076B (da) 1989-11-06
FI821121L (fi) 1982-10-02
GR76062B (it) 1984-08-03
ES8302622A1 (es) 1983-02-01
PT74677A (en) 1982-04-01
NO821088L (no) 1982-10-04
US4423244A (en) 1983-12-27
YU42606B (en) 1988-10-31
DK157076C (da) 1990-04-09
LU84044A1 (fr) 1983-02-22
SE8501744L (sv) 1985-04-09
NO157733B (no) 1988-02-01
SE466199B (sv) 1992-01-13
DK256589D0 (da) 1989-05-26
DE3212170C2 (it) 1989-03-02
DK256589A (da) 1989-05-26
FR2504918B1 (fr) 1985-06-14
GB2098981A (en) 1982-12-01
HU186852B (en) 1985-10-28
FI78455C (fi) 1989-08-10
FI78455B (fi) 1989-04-28
IE52378B1 (en) 1987-09-30
IE820770L (en) 1982-10-01
PT74677B (en) 1983-10-31
JPH0231704B2 (it) 1990-07-16
GB2098981B (en) 1984-10-24
DE3212170A1 (de) 1982-10-21

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970312