SE453089B - Imidazo-rifamycinderivat, forfarande for framstellning derav och farmaceutisk komposition - Google Patents

Imidazo-rifamycinderivat, forfarande for framstellning derav och farmaceutisk komposition

Info

Publication number
SE453089B
SE453089B SE8103216A SE8103216A SE453089B SE 453089 B SE453089 B SE 453089B SE 8103216 A SE8103216 A SE 8103216A SE 8103216 A SE8103216 A SE 8103216A SE 453089 B SE453089 B SE 453089B
Authority
SE
Sweden
Prior art keywords
nothing
formula
hydrogen
imidazo
chemical bond
Prior art date
Application number
SE8103216A
Other languages
English (en)
Swedish (sv)
Other versions
SE8103216L (sv
Inventor
E Marchi
L Montecchi
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of SE8103216L publication Critical patent/SE8103216L/xx
Publication of SE453089B publication Critical patent/SE453089B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE8103216A 1980-05-22 1981-05-21 Imidazo-rifamycinderivat, forfarande for framstellning derav och farmaceutisk komposition SE453089B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03429/80A IT1154655B (it) 1980-05-22 1980-05-22 Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Publications (2)

Publication Number Publication Date
SE8103216L SE8103216L (sv) 1981-11-23
SE453089B true SE453089B (sv) 1988-01-11

Family

ID=11107198

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8103216A SE453089B (sv) 1980-05-22 1981-05-21 Imidazo-rifamycinderivat, forfarande for framstellning derav och farmaceutisk komposition

Country Status (25)

Country Link
US (1) US4341785A (hu)
JP (1) JPS5711987A (hu)
AR (1) AR226212A1 (hu)
AT (1) AT373599B (hu)
AU (1) AU537093B2 (hu)
BE (1) BE888895A (hu)
CA (1) CA1142518A (hu)
CH (1) CH648037A5 (hu)
DE (1) DE3120460A1 (hu)
DK (1) DK157876C (hu)
EG (1) EG14891A (hu)
ES (1) ES502906A0 (hu)
FI (1) FI69467C (hu)
FR (1) FR2482967A1 (hu)
GB (1) GB2079270B (hu)
GR (1) GR75640B (hu)
IE (1) IE51204B1 (hu)
IT (1) IT1154655B (hu)
LU (1) LU83376A1 (hu)
NL (1) NL187022C (hu)
NO (1) NO155622C (hu)
PH (2) PH17207A (hu)
PT (1) PT73064B (hu)
SE (1) SE453089B (hu)
ZA (1) ZA813430B (hu)

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EP0861660B9 (en) * 1997-02-28 2006-06-28 Kaneka Corporation Curative medicine for disease caused by infection of Helicobacter
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US7078399B2 (en) * 2001-12-13 2006-07-18 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US8758804B2 (en) * 2002-11-05 2014-06-24 Fadim S.R.L. Controlled and continued delivery of rifaximin and/or other substances
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
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US7902206B2 (en) * 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7906542B2 (en) * 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
US7923553B2 (en) * 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7256187B2 (en) * 2004-03-10 2007-08-14 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime derivatives effective against drug-resistant microbes
US7265107B2 (en) * 2004-03-10 2007-09-04 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes
US7202246B2 (en) * 2004-06-09 2007-04-10 Cumbre Pharmaceuticals Inc. Spiro-rifamycin derivatives targeting RNA polymerase
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
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ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
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US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
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US8383151B2 (en) 2007-07-06 2013-02-26 Lupin Limited Pharmaceutical compositions of rifaximin
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
ME01032B (me) 2008-02-25 2012-10-20 Salix Pharmaceuticals Ltd FORME RIFAKSIMINA l NJIHOVA UPOTREBA
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
US8309569B2 (en) 2008-02-26 2012-11-13 Salix Pharmaceuticals, Ltd. Methods for treating diarrhea-associated irritable bowel syndrome
US20090324736A1 (en) 2008-05-07 2009-12-31 Salix Pharmaceuticals, Ltd. Methods of treating bowel diseases by administering a bowel cleanser and an antibiotic
WO2010019511A2 (en) 2008-08-13 2010-02-18 Targanta Therapeutics Corp. Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
CA2736285C (en) 2008-09-26 2016-08-23 Aska Pharmaceutical Co., Ltd. Agent for preventing and/or treating functional gastrointestinal disorder
HUE065491T2 (hu) 2008-10-02 2024-05-28 Salix Pharmaceuticals Ltd A hepatikus enkefalopátia kezelése rifaximin alkalmazásával
KR20110107806A (ko) 2008-12-10 2011-10-04 시플라 리미티드 리팍시민 복합체
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
MX2011012829A (es) 2009-06-02 2012-02-28 Salix Pharmaceuticals Ltd Metodos para tratar encefalopatia hepatica.
MX2012002895A (es) 2009-09-13 2012-05-22 Salix Pharmaceuticals Ltd Metodos para tratar el sindrome de intestino irritado (ibs).
KR102456997B1 (ko) 2009-10-27 2022-10-19 루핀 리미티드 리팍시민의 고형 분산물
NZ600362A (en) 2009-11-23 2014-08-29 Cipla Ltd Topical foam composition
WO2011080691A1 (en) 2009-12-28 2011-07-07 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
EP3650022A1 (en) 2010-02-18 2020-05-13 Salix Pharmaceuticals, Ltd. Methods for treating rifampin resistant clostridium difficilis infections
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
US9211258B2 (en) 2010-03-10 2015-12-15 Lupin Limited Rifaximin ready-to-use suspension
CA2804635C (en) 2010-07-12 2019-09-10 Salix Pharmaceuticals, Ltd. Formulations of rifaximin and uses thereof
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
AU2012214239B2 (en) 2011-02-11 2016-06-30 Salix Pharmaceuticals, Ltd. Forms of Rifaximin and uses thereof
CA2834829A1 (en) 2011-05-02 2012-11-08 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
ITMI20110890A1 (it) 2011-05-19 2012-11-20 A M S A Anonima Materie Sint & Affini S P A Polimorfo di rifaximina e processo per la sua preparazione
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
RU2496475C2 (ru) 2011-10-26 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция и набор для лечения бактериальных инфекций
WO2013067394A1 (en) 2011-11-02 2013-05-10 Salix Pharmaceuticals, Ltd Methods for treating irritable bowel syndrome (ibs) and infections
WO2013112809A2 (en) 2012-01-25 2013-08-01 Salix Pharmaceuticals, Ltd Rifaximin derivative and uses thereof
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
WO2014091432A1 (en) 2012-12-12 2014-06-19 Ranbaxy Laboratories Limited Pharmaceutical compositions of rifaximin
US20160038468A1 (en) 2013-03-15 2016-02-11 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections
JP2016516988A (ja) 2013-03-15 2016-06-09 アルファ ワッセルマン ソシエタ ペル アチオニＡｌｆａ Ｗａｓｓｅｒｍａｎｎ Ｓ．Ｐ．Ａ． 膣感染症を診断するための方法
AU2014252219B2 (en) 2013-04-12 2018-11-22 Alfasigma S.P.A. NSAID administration and related compositions, methods and systems.
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
EP2927235B1 (en) 2014-03-31 2017-02-08 Euticals S.P.A. Polymorphic mixture of rifaximin and its use for the preparation of solid formulations
WO2015171493A1 (en) 2014-05-04 2015-11-12 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
RS59250B1 (sr) 2014-05-12 2019-10-31 Alfasigma Spa Novi solvatni kristalni oblik rifaksimina, njegova proizvodnja, kompozicije i upotreba
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
WO2018064472A1 (en) 2016-09-30 2018-04-05 Salix Pharmaceuticals, Ltd. Solid dispersion forms of rifaximin
EP3645539B1 (en) * 2017-06-26 2021-04-07 Biofer S.p.A. Pyrido-imidazo rifamycin derivatives as antibacterial agent
IT201700091912A1 (it) * 2017-08-08 2019-02-08 Biofer Spa Nuove pirido-imidazo rifamicine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE273377C (hu) *
AT273377B (de) * 1967-03-01 1969-08-11 Lepetit Spa Verfahren zur Herstellung von neuen Rifamycinen
AT344898B (de) * 1975-06-13 1978-08-10 Archifar Ind Chim Trentino Verfahren zur herstellung neuer rifamycin-verbindungen
DK345977A (da) * 1976-09-30 1978-03-31 Archifar Ind Chim Trentino G rifamycinforbindelser og fremgangsmaade til deres fremstillin
CH629212A5 (it) * 1976-10-18 1982-04-15 Erba Farmitalia Procedimento per la preparazione di composti di rifamicina.
CH633014A5 (en) * 1978-06-09 1982-11-15 Erba Farmitalia Rifamycin compounds

Also Published As

Publication number Publication date
CA1142518A (en) 1983-03-08
NO155622C (no) 1987-04-29
JPS6123192B2 (hu) 1986-06-04
DK157876C (da) 1990-07-30
ES8203388A1 (es) 1982-04-01
DE3120460C2 (hu) 1990-12-13
PH18704A (en) 1985-09-05
PH17207A (en) 1984-06-19
AT373599B (de) 1984-02-10
ES502906A0 (es) 1982-04-01
FI811565L (fi) 1981-11-23
IT8003429A0 (it) 1980-05-22
US4341785A (en) 1982-07-27
PT73064A (en) 1981-06-01
NL187022C (nl) 1991-05-01
JPS5711987A (en) 1982-01-21
DK157876B (da) 1990-02-26
FR2482967A1 (fr) 1981-11-27
AU537093B2 (en) 1984-06-07
BE888895A (fr) 1981-09-16
GB2079270A (en) 1982-01-20
DE3120460A1 (de) 1982-03-11
FI69467C (fi) 1986-02-10
IE811139L (en) 1981-11-22
AR226212A1 (es) 1982-06-15
ZA813430B (en) 1982-06-30
NO155622B (no) 1987-01-19
NO811731L (no) 1981-11-23
DK224781A (da) 1981-11-23
FR2482967B1 (hu) 1985-03-29
GR75640B (hu) 1984-08-02
ATA222781A (de) 1983-06-15
FI69467B (fi) 1985-10-31
IE51204B1 (en) 1986-10-29
NL187022B (nl) 1990-12-03
AU7065581A (en) 1981-11-26
LU83376A1 (fr) 1981-09-11
GB2079270B (en) 1984-01-18
CH648037A5 (de) 1985-02-28
NL8102290A (nl) 1981-12-16
EG14891A (en) 1985-12-31
IT1154655B (it) 1987-01-21
PT73064B (en) 1982-07-05
SE8103216L (sv) 1981-11-23

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