SE450573B - 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition - Google Patents
1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk kompositionInfo
- Publication number
- SE450573B SE450573B SE8301412A SE8301412A SE450573B SE 450573 B SE450573 B SE 450573B SE 8301412 A SE8301412 A SE 8301412A SE 8301412 A SE8301412 A SE 8301412A SE 450573 B SE450573 B SE 450573B
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- formula
- phenyl
- compound
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8207637 | 1982-03-16 | ||
GB838303089A GB8303089D0 (en) | 1983-02-04 | 1983-02-04 | Substituted 1h-pyrazolo 1,5-a pyrimidines |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8301412D0 SE8301412D0 (sv) | 1983-03-15 |
SE8301412L SE8301412L (sv) | 1983-09-17 |
SE450573B true SE450573B (sv) | 1987-07-06 |
Family
ID=26282260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8301412A SE450573B (sv) | 1982-03-16 | 1983-03-15 | 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition |
Country Status (13)
Country | Link |
---|---|
US (1) | US4482555A (fi) |
AU (1) | AU557300B2 (fi) |
CA (1) | CA1192546A (fi) |
CH (1) | CH654306A5 (fi) |
DE (1) | DE3309432A1 (fi) |
DK (1) | DK120783A (fi) |
FI (1) | FI74469C (fi) |
FR (1) | FR2523582B1 (fi) |
IL (1) | IL68133A (fi) |
IT (1) | IT1194555B (fi) |
NL (1) | NL8300934A (fi) |
SE (1) | SE450573B (fi) |
SU (1) | SU1366060A3 (fi) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6245759B1 (en) | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
MY125533A (en) | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
EP1782859A3 (en) * | 2003-04-11 | 2009-09-30 | High Point Pharmaceuticals, LLC | Pharmaceutical use of substituted pyrazolo [1,5- a]pyrimidines |
EP1615697A2 (en) * | 2003-04-11 | 2006-01-18 | Novo Nordisk A/S | New pyrazolo[1,5-a] pyrimidine derivatives and pharmaceutical use thereof |
US7772232B2 (en) | 2004-04-15 | 2010-08-10 | Bristol-Myers Squibb Company | Quinazolinyl compounds as inhibitors of potassium channel function |
WO2006040329A1 (en) * | 2004-10-12 | 2006-04-20 | Novo Nordisk A/S | 1 ibeta- hydroxysteroid dehydrogenase type 1 active spiro compounds |
CN101355938A (zh) * | 2005-11-01 | 2009-01-28 | 高点制药有限责任公司 | 取代的酰胺的药学应用 |
EA200801243A1 (ru) * | 2005-11-01 | 2008-10-30 | Транстек Фарма | Фармацевтическое применение замещенных амидов |
CA2646588A1 (en) * | 2006-03-21 | 2007-09-27 | High Point Pharmaceuticals, Llc | Adamantane derivatives for the treatment of the metabolic syndrome |
CA2648074A1 (en) | 2006-04-07 | 2007-10-18 | High Point Pharmaceuticals, Llc | 11.beta.-hydroxysteroid dehydrogenase type 1 active compounds |
US20090306048A1 (en) * | 2006-06-16 | 2009-12-10 | John Paul Kilburn | Pharmaceutical use of substituted piperidine carboxamides |
EP1878721A1 (en) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors |
US8048908B2 (en) * | 2006-07-13 | 2011-11-01 | High Point Pharmaceuticals, Llc | 11β-hydroxysteroid dehydrogenase type 1 active compounds |
MX2009008228A (es) | 2007-02-23 | 2009-08-12 | High Point Pharmaceuticals Llc | N-adamantil benzamidas como inhibidores de la dehidrogenasa 11-beta-hidroxiesteroide. |
WO2008101907A2 (en) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
WO2008101886A1 (en) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
US20110003852A1 (en) * | 2007-02-23 | 2011-01-06 | Soren Ebdrup | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
EA200970841A1 (ru) * | 2007-03-09 | 2010-04-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Фармацевтическое применение замещенных амидов |
JP2010522766A (ja) * | 2007-03-28 | 2010-07-08 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 11ベータ−hsd1活性化合物 |
EP2152081B1 (en) * | 2007-04-11 | 2012-10-24 | High Point Pharmaceuticals, LLC | Novel compounds |
WO2008134221A1 (en) * | 2007-04-24 | 2008-11-06 | High Point Pharmaceuticals, Llc | Pharmaceutical use of substituted amides |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3907799A (en) * | 1971-08-16 | 1975-09-23 | Icn Pharmaceuticals | Xanthine oxidase inhibitors |
BE786611A (fr) * | 1971-08-16 | 1973-01-22 | Int Chem & Nuclear Corp | Nouveaux inhibiteurs de xanthine-oxydase et leur procede de preparatio |
BE792533A (fr) * | 1971-12-09 | 1973-06-08 | Int Chem & Nuclear Corp | Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation |
US3925385A (en) * | 1972-04-20 | 1975-12-09 | Icn Pharmaceuticals | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
US4093617A (en) * | 1974-11-12 | 1978-06-06 | Icn Pharmaceuticals, Inc. | 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines |
US4048184A (en) * | 1976-11-15 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 6-Phenyl-2H-pyrazolo[3,4-b]pyridines |
US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
-
1983
- 1983-03-09 AU AU12304/83A patent/AU557300B2/en not_active Ceased
- 1983-03-10 US US06/474,205 patent/US4482555A/en not_active Expired - Fee Related
- 1983-03-11 IT IT20024/83A patent/IT1194555B/it active
- 1983-03-11 CH CH1325/83A patent/CH654306A5/de not_active IP Right Cessation
- 1983-03-15 NL NL8300934A patent/NL8300934A/xx active Search and Examination
- 1983-03-15 FI FI830864A patent/FI74469C/fi not_active IP Right Cessation
- 1983-03-15 FR FR8304253A patent/FR2523582B1/fr not_active Expired
- 1983-03-15 SU SU833565748A patent/SU1366060A3/ru active
- 1983-03-15 CA CA000423644A patent/CA1192546A/en not_active Expired
- 1983-03-15 SE SE8301412A patent/SE450573B/sv not_active IP Right Cessation
- 1983-03-15 DK DK120783A patent/DK120783A/da not_active Application Discontinuation
- 1983-03-15 IL IL68133A patent/IL68133A/xx unknown
- 1983-03-16 DE DE19833309432 patent/DE3309432A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
FI830864L (fi) | 1983-09-17 |
FR2523582A1 (fr) | 1983-09-23 |
CH654306A5 (de) | 1986-02-14 |
AU1230483A (en) | 1983-09-22 |
DK120783A (da) | 1983-09-17 |
CA1192546A (en) | 1985-08-27 |
SE8301412D0 (sv) | 1983-03-15 |
IL68133A0 (en) | 1983-06-15 |
SE8301412L (sv) | 1983-09-17 |
FR2523582B1 (fr) | 1985-12-06 |
DE3309432A1 (de) | 1983-09-22 |
IL68133A (en) | 1985-12-31 |
SU1366060A3 (ru) | 1988-01-07 |
FI74469C (fi) | 1988-02-08 |
NL8300934A (nl) | 1983-10-17 |
FI830864A0 (fi) | 1983-03-15 |
US4482555A (en) | 1984-11-13 |
IT8320024A0 (it) | 1983-03-11 |
AU557300B2 (en) | 1986-12-18 |
FI74469B (fi) | 1987-10-30 |
IT1194555B (it) | 1988-09-22 |
DK120783D0 (da) | 1983-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE450573B (sv) | 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition | |
CN105829307B (zh) | 用作tnf活性调节剂的四氢咪唑并吡啶衍生物 | |
AU2023237060A1 (en) | TYK2 inhibitors and uses thereof | |
DE60004655T2 (de) | Pyridin- und pyrimidinderivate und deren verwendung als inhibitor von cytokinbedingten krankheiten | |
DE3546658C2 (fi) | ||
SE454698B (sv) | 6-karboxamidoderivat av 5-oxo-5h-1,3,4-tiadiazolo/3,2-a/pyrimidiner, forfarande for deras framstellning samt farmaceutiska kompositioner innehallande desamma | |
DE69524598T2 (de) | Kondensierte imidazolderivate, ihre herstellung und verwendung | |
JP2007534735A (ja) | 抗ウイルス剤として使用するためのモルホリニルアニリノキナゾリン誘導体 | |
US4808594A (en) | Imidopyridines useful in therapy | |
DD139854A5 (de) | Verfahren zur herstellung neuer kondensierter pyrimidin-derivate | |
WO2000041695A1 (de) | Verwendung von pyrimidinderivaten zur prophylaxe und therapie der zerebralen ischämie | |
CA1309407C (en) | Cinnoline-carboxamides and process for their preparation | |
CA1119174A (en) | N-(benzothienopyrazol)amide antirhinoviral agents | |
SE437158B (sv) | Substituerade pyrido/1,2-a/pyrimidiner, forfarande for framstellning derav och farmaceutisk komposition | |
EP0964865B1 (en) | Pharmaceutically active tricyclic amines | |
JPS61152682A (ja) | ピリドンカルボン酸誘導体、そのエステルおよびその塩 | |
US3636041A (en) | 4 5-dihydro-7h-thieno(2 3-c)thiopyrans | |
WO1992005173A1 (en) | Substituted tricyclic compounds | |
US3830813A (en) | 2-(5'-nitro-2'-furyl)-thieno(2,3-d)pyridines and salts thereof | |
AU616916B2 (en) | 4h-quinolizin-4-one compounds exhibiting therapeutic activities | |
SE447478B (sv) | Substituerade etenylderivat av ih-pyrazolo(1,5-a)pyrimidin, forfarande for deras framstellning och farmaceutisk komposition | |
GB2116971A (en) | 1H-pyrazolo [1,5-a] pyrimidines | |
SE442511B (sv) | 2,6-bis-(aminoacylamino)-benso-/1,2-d:5,4-d'/-bistiazoler och 2-amino-6-(aminoacylamino)-benso-/1,2-d:5,4-d'/-bistiazoler samt forfarande for deras framstellning | |
JPH03294277A (ja) | ピペリジン誘導体 | |
JPS58167590A (ja) | 置換された1H−ピラゾロ〔1.5−a〕ピリミジンおよびその製法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 8301412-6 Effective date: 19900125 Format of ref document f/p: F |