DE69524598T2 - Kondensierte imidazolderivate, ihre herstellung und verwendung - Google Patents

Kondensierte imidazolderivate, ihre herstellung und verwendung

Info

Publication number
DE69524598T2
DE69524598T2 DE69524598T DE69524598T DE69524598T2 DE 69524598 T2 DE69524598 T2 DE 69524598T2 DE 69524598 T DE69524598 T DE 69524598T DE 69524598 T DE69524598 T DE 69524598T DE 69524598 T2 DE69524598 T2 DE 69524598T2
Authority
DE
Germany
Prior art keywords
pct
production
date dec
condensed imidazole
imidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69524598T
Other languages
English (en)
Other versions
DE69524598D1 (de
Inventor
Muneo Takatani
Hitoshi Ikeda
Kyoko Iida
Hidenori Abe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69524598D1 publication Critical patent/DE69524598D1/de
Publication of DE69524598T2 publication Critical patent/DE69524598T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
DE69524598T 1994-06-20 1995-06-15 Kondensierte imidazolderivate, ihre herstellung und verwendung Expired - Fee Related DE69524598T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13760094 1994-06-20
JP6412895 1995-03-24
PCT/JP1995/001192 WO1995035296A1 (en) 1994-06-20 1995-06-15 Condensed imidazole compounds, their production and use

Publications (2)

Publication Number Publication Date
DE69524598D1 DE69524598D1 (de) 2002-01-24
DE69524598T2 true DE69524598T2 (de) 2002-07-11

Family

ID=26405261

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524598T Expired - Fee Related DE69524598T2 (de) 1994-06-20 1995-06-15 Kondensierte imidazolderivate, ihre herstellung und verwendung

Country Status (8)

Country Link
US (1) US5840732A (de)
EP (1) EP0767790B1 (de)
CN (1) CN1046725C (de)
AT (1) ATE210663T1 (de)
AU (1) AU2682695A (de)
CA (1) CA2191979A1 (de)
DE (1) DE69524598T2 (de)
WO (1) WO1995035296A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953355A4 (de) * 1996-05-31 2002-02-27 Sankyo Co Heilmittel für autoimmunkrankheiten
SI1005445T1 (en) * 1997-08-22 2004-12-31 F. Hoffmann-La Roche Ag N-alkanoylphenylalanine derivatives
US6455550B1 (en) 1997-08-22 2002-09-24 Hoffmann-La Roche Inc. N-alkanoylphenylalanine derivatives
US6229011B1 (en) 1997-08-22 2001-05-08 Hoffman-La Roche Inc. N-aroylphenylalanine derivative VCAM-1 inhibitors
DE69824183T2 (de) * 1997-08-22 2005-04-21 Hoffmann La Roche N-alkanoylphenylalaninderivate
AU9651198A (en) 1997-11-11 1999-05-31 Ono Pharmaceutical Co. Ltd. Fused pyrazine compounds
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
RU2238265C2 (ru) 1999-02-18 2004-10-20 Ф.Хоффманн-Ля Рош Аг Фенилаланиноловые производные
WO2000048994A1 (en) 1999-02-18 2000-08-24 F. Hoffmann-La Roche Ag Thioamide derivatives
MXPA02000625A (es) * 1999-07-21 2002-07-02 Boehringer Ingelheim Pharma Pequenas moleculas utiles en el tratamiento de enfermedades inflamatorias.
CA2475595C (en) * 2002-02-22 2012-07-10 3M Innovative Properties Company Method of reducing and preventing uvb-induced immunosuppression
ITFI20030058A1 (it) * 2003-03-06 2004-09-07 Univ Firenze Formulazioni farmaceutiche contenenti tiazolidinedioni
AU2007337895C1 (en) 2006-12-22 2014-07-31 Astex Therapeutics Limited Tricyclic amine derivatives as protein tyrosine kinase inhibitors
US8895745B2 (en) 2006-12-22 2014-11-25 Astex Therapeutics Limited Bicyclic heterocyclic compounds as FGFR inhibitors
GB0720038D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New compounds
GB0720041D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New Compounds
GB0810902D0 (en) 2008-06-13 2008-07-23 Astex Therapeutics Ltd New compounds
EP2365969B1 (de) 2008-11-20 2017-03-22 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Neue Antibiofilmmittel
GB0906472D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
GB0906470D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
EP3239150B1 (de) 2014-12-24 2020-02-05 Takeda Pharmaceutical Company Limited Heterocyclische verbindung
CN107286156A (zh) * 2016-04-05 2017-10-24 江苏新元素医药科技有限公司 新型urat1抑制剂及其在医药上的应用
US11673891B2 (en) 2017-11-14 2023-06-13 Dana-Farber Cancer Institute, Inc. Imidazopyrimidine compounds and uses thereof
CN111587114A (zh) 2017-11-14 2020-08-25 儿童医学中心公司 用于调节人免疫应答的咪唑并嘧啶的用途
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB656607A (en) * 1948-01-23 1951-08-29 Kodak Ltd Improvements in dyes for use in photographic materials
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
CA1164459A (en) * 1980-11-11 1984-03-27 Yung-Hsiung Yang Process for preparing (imidazo¬1,2-a|pyridine- 2-yl)-carbostyril or -3,4-dihydrocarbostyryl derivatives
US4470986A (en) * 1982-12-21 1984-09-11 Ciba-Geigy Corporation Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
EP0228006A1 (de) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridinverbindungen und Verfahren zu ihrer Herstellung
JPS6383067A (ja) * 1986-09-26 1988-04-13 Sumitomo Pharmaceut Co Ltd 新規コハク酸イミド誘導体
JPS6383085A (ja) * 1986-09-26 1988-04-13 Sumitomo Pharmaceut Co Ltd 新規なイミド誘導体
CA1327796C (en) * 1987-07-16 1994-03-15 Jorg Senn-Bilfinger Diazoles
US5082838A (en) * 1989-06-21 1992-01-21 Takeda Chemical Industries, Ltd. Sulfur-containing fused pyrimidine derivatives, their production and use
US5244908A (en) * 1990-07-30 1993-09-14 Takeda Chemical Industries, Ltd. Imidazopyridine derivatives and their pharmaceutical use
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
EP0612729B1 (de) * 1991-05-10 1997-04-23 Takeda Chemical Industries, Ltd. Pyridinderivate, deren Herstellung und Anwendung
US5457102A (en) * 1994-07-07 1995-10-10 Janssen Pharmaceutica, N.V. Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
CN1151161A (zh) 1997-06-04
WO1995035296A1 (en) 1995-12-28
CN1046725C (zh) 1999-11-24
ATE210663T1 (de) 2001-12-15
EP0767790B1 (de) 2001-12-12
AU2682695A (en) 1996-01-15
EP0767790A1 (de) 1997-04-16
DE69524598D1 (de) 2002-01-24
US5840732A (en) 1998-11-24
CA2191979A1 (en) 1995-12-28

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee