DE69524598D1 - Kondensierte imidazolderivate, ihre herstellung und verwendung - Google Patents

Kondensierte imidazolderivate, ihre herstellung und verwendung

Info

Publication number
DE69524598D1
DE69524598D1 DE69524598T DE69524598T DE69524598D1 DE 69524598 D1 DE69524598 D1 DE 69524598D1 DE 69524598 T DE69524598 T DE 69524598T DE 69524598 T DE69524598 T DE 69524598T DE 69524598 D1 DE69524598 D1 DE 69524598D1
Authority
DE
Germany
Prior art keywords
pct
production
date dec
condensed imidazole
imidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69524598T
Other languages
English (en)
Other versions
DE69524598T2 (de
Inventor
Muneo Takatani
Hitoshi Ikeda
Kyoko Iida
Hidenori Abe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69524598D1 publication Critical patent/DE69524598D1/de
Publication of DE69524598T2 publication Critical patent/DE69524598T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69524598T 1994-06-20 1995-06-15 Kondensierte imidazolderivate, ihre herstellung und verwendung Expired - Fee Related DE69524598T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13760094 1994-06-20
JP6412895 1995-03-24
PCT/JP1995/001192 WO1995035296A1 (en) 1994-06-20 1995-06-15 Condensed imidazole compounds, their production and use

Publications (2)

Publication Number Publication Date
DE69524598D1 true DE69524598D1 (de) 2002-01-24
DE69524598T2 DE69524598T2 (de) 2002-07-11

Family

ID=26405261

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524598T Expired - Fee Related DE69524598T2 (de) 1994-06-20 1995-06-15 Kondensierte imidazolderivate, ihre herstellung und verwendung

Country Status (8)

Country Link
US (1) US5840732A (de)
EP (1) EP0767790B1 (de)
CN (1) CN1046725C (de)
AT (1) ATE210663T1 (de)
AU (1) AU2682695A (de)
CA (1) CA2191979A1 (de)
DE (1) DE69524598T2 (de)
WO (1) WO1995035296A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045141A1 (fr) * 1996-05-31 1997-12-04 Sankyo Company, Limited Remede pour maladies auto-immunes
EP1403247A1 (de) * 1997-08-22 2004-03-31 F.Hoffmann-La Roche Ag N-Alkanoylphenylalaninderivate
US6229011B1 (en) 1997-08-22 2001-05-08 Hoffman-La Roche Inc. N-aroylphenylalanine derivative VCAM-1 inhibitors
US6455550B1 (en) 1997-08-22 2002-09-24 Hoffmann-La Roche Inc. N-alkanoylphenylalanine derivatives
NZ502813A (en) * 1997-08-22 2002-10-25 F N-aroylphenylalanine derivatives as inhibitors of the interaction between a4 containing integrins and VCAM-1
CN1285834A (zh) 1997-11-11 2001-02-28 小野药品工业株式会社 稠合吡嗪化合物
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
HUP0200155A3 (en) 1999-02-18 2005-04-28 Hoffmann La Roche Thioamide derivatives, pharmaceutical compositions containing them and their use
ID30057A (id) 1999-02-18 2001-11-01 Hoffmann La Roche Turunan fenilalaninol
JP3833532B2 (ja) * 1999-07-21 2006-10-11 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 炎症性疾患の治療において有用な小分子
SI1478327T1 (sl) * 2002-02-22 2015-08-31 Meda Ab Metoda za zmanjšanje in zdravljenje imunosupresije, inducirane z UV-B
ITFI20030058A1 (it) * 2003-03-06 2004-09-07 Univ Firenze Formulazioni farmaceutiche contenenti tiazolidinedioni
AU2007337895C1 (en) 2006-12-22 2014-07-31 Astex Therapeutics Limited Tricyclic amine derivatives as protein tyrosine kinase inhibitors
EP2114941B1 (de) 2006-12-22 2015-03-25 Astex Therapeutics Limited Bicyclische heterocyclische verbindungen als fgfr-inhibitoren
GB0720041D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New Compounds
GB0720038D0 (en) 2007-10-12 2007-11-21 Astex Therapeutics Ltd New compounds
GB0810902D0 (en) 2008-06-13 2008-07-23 Astex Therapeutics Ltd New compounds
EP2365969B1 (de) 2008-11-20 2017-03-22 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Neue Antibiofilmmittel
GB0906470D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
GB0906472D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
EP3239150B1 (de) 2014-12-24 2020-02-05 Takeda Pharmaceutical Company Limited Heterocyclische verbindung
CN107286156A (zh) * 2016-04-05 2017-10-24 江苏新元素医药科技有限公司 新型urat1抑制剂及其在医药上的应用
US11673891B2 (en) 2017-11-14 2023-06-13 Dana-Farber Cancer Institute, Inc. Imidazopyrimidine compounds and uses thereof
US11730810B2 (en) 2017-11-14 2023-08-22 Children's Medical Center Corporation Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB656607A (en) * 1948-01-23 1951-08-29 Kodak Ltd Improvements in dyes for use in photographic materials
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
CA1164459A (en) * 1980-11-11 1984-03-27 Yung-Hsiung Yang Process for preparing (imidazo¬1,2-a|pyridine- 2-yl)-carbostyril or -3,4-dihydrocarbostyryl derivatives
US4470986A (en) * 1982-12-21 1984-09-11 Ciba-Geigy Corporation Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
EP0228006A1 (de) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridinverbindungen und Verfahren zu ihrer Herstellung
JPS6383085A (ja) * 1986-09-26 1988-04-13 Sumitomo Pharmaceut Co Ltd 新規なイミド誘導体
JPS6383067A (ja) * 1986-09-26 1988-04-13 Sumitomo Pharmaceut Co Ltd 新規コハク酸イミド誘導体
PT87988B (pt) * 1987-07-16 1995-05-04 Byk Gulden Lomberg Chem Fab Processo para a preparacao de diazois e de composicoes farmaceuticas que os contem
US5082838A (en) * 1989-06-21 1992-01-21 Takeda Chemical Industries, Ltd. Sulfur-containing fused pyrimidine derivatives, their production and use
ES2069137T3 (es) * 1990-07-30 1995-05-01 Takeda Chemical Industries Ltd Derivados de imidazopiridina y su uso.
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
DE69209576D1 (de) * 1991-05-10 1996-05-09 Takeda Chemical Industries Ltd Pyridinderivate, deren Herstellung und Anwendung
US5457102A (en) * 1994-07-07 1995-10-10 Janssen Pharmaceutica, N.V. Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
CN1151161A (zh) 1997-06-04
WO1995035296A1 (en) 1995-12-28
ATE210663T1 (de) 2001-12-15
CA2191979A1 (en) 1995-12-28
AU2682695A (en) 1996-01-15
US5840732A (en) 1998-11-24
DE69524598T2 (de) 2002-07-11
EP0767790B1 (de) 2001-12-12
EP0767790A1 (de) 1997-04-16
CN1046725C (zh) 1999-11-24

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee