SE448543B - /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma - Google Patents

/3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma

Info

Publication number
SE448543B
SE448543B SE8204817A SE8204817A SE448543B SE 448543 B SE448543 B SE 448543B SE 8204817 A SE8204817 A SE 8204817A SE 8204817 A SE8204817 A SE 8204817A SE 448543 B SE448543 B SE 448543B
Authority
SE
Sweden
Prior art keywords
carbon atoms
group
groups
general formula
substituted
Prior art date
Application number
SE8204817A
Other languages
English (en)
Swedish (sv)
Other versions
SE8204817D0 (sv
SE8204817L (sv
Inventor
E Lunt
M F G Stevens
R Stone
K R H Woolridge
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of SE8204817D0 publication Critical patent/SE8204817D0/xx
Publication of SE8204817L publication Critical patent/SE8204817L/xx
Publication of SE448543B publication Critical patent/SE448543B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SE8204817A 1981-08-24 1982-08-23 /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma SE448543B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (3)

Publication Number Publication Date
SE8204817D0 SE8204817D0 (sv) 1982-08-23
SE8204817L SE8204817L (sv) 1983-02-25
SE448543B true SE448543B (sv) 1987-03-02

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8204817A SE448543B (sv) 1981-08-24 1982-08-23 /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma

Country Status (29)

Country Link
JP (1) JPS5843975A (enExample)
KR (1) KR890000094B1 (enExample)
AT (1) AT380256B (enExample)
AU (1) AU571430B2 (enExample)
BE (1) BE894175A (enExample)
CA (1) CA1197247A (enExample)
CH (1) CH655114A5 (enExample)
DE (2) DE19975037I2 (enExample)
DK (1) DK161147C (enExample)
ES (1) ES8400438A1 (enExample)
FI (1) FI73434C (enExample)
FR (1) FR2511679A1 (enExample)
GB (1) GB2104522B (enExample)
GE (1) GEP19960641B (enExample)
GR (1) GR76863B (enExample)
HU (1) HU186107B (enExample)
IE (1) IE53408B1 (enExample)
IL (1) IL66606A (enExample)
IT (1) IT1152505B (enExample)
LT (1) LT2436B (enExample)
LU (1) LU84347A1 (enExample)
LV (2) LV5511A3 (enExample)
NL (2) NL192739C (enExample)
NZ (1) NZ201668A (enExample)
OA (1) OA07174A (enExample)
SE (1) SE448543B (enExample)
SU (1) SU1447284A3 (enExample)
UA (1) UA5971A1 (enExample)
ZA (1) ZA826120B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
DK0866709T3 (da) * 1995-09-25 2007-03-19 Sanofi Aventis Us Llc 1,2,4-benzotriazinoxidformuleringer
BRPI0417117A (pt) 2003-12-30 2007-03-06 Chemagis Ltd temozolomida cristalizada, processo de preparação de temozolomida cristalizada, composição farmacêutica, método de produção de medicamento contendo temozolomida e método de tratamento de uma condição médica para a qual a termozolomida é benéfica
ES2552338T3 (es) 2005-01-21 2015-11-27 Astex Therapeutics Limited Compuestos farmacéuticos
PE20080695A1 (es) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
EP2213673B1 (en) 2007-10-23 2013-06-05 Msd K.K. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
CN102256978A (zh) * 2008-11-24 2011-11-23 利莱恩斯生命科学有限公司 制备四嗪衍生物的工艺
US8481503B2 (en) 2009-03-06 2013-07-09 Merck Sharp & Dohme Corp. Combination cancer therapy with an AKT inhibitor and other anticancer agents
BRPI1011822A2 (pt) 2009-06-23 2016-03-29 Pharminox Ltd "compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação"
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
WO2013055985A1 (en) 2011-10-12 2013-04-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
EP3429571B1 (en) 2016-03-15 2025-10-08 Oryzon Genomics, S.A. Combinations of lsd1 inhibitors for use in the treatment of neoplastic diseases
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
SE8204817D0 (sv) 1982-08-23
AU571430B2 (en) 1988-04-21
DE3231255C2 (enExample) 1992-02-27
LT2436B (lt) 1994-02-15
CA1197247A (fr) 1985-11-26
DE3231255A1 (de) 1983-03-03
HU186107B (en) 1985-06-28
JPH045029B2 (enExample) 1992-01-30
KR890000094B1 (ko) 1989-03-07
IL66606A0 (en) 1982-12-31
KR840001175A (ko) 1984-03-28
IL66606A (en) 1987-07-31
NL192739B (nl) 1997-09-01
SU1447284A3 (ru) 1988-12-23
IT8222938A1 (it) 1984-02-23
FI822921A0 (fi) 1982-08-23
BE894175A (fr) 1983-02-23
IT8222938A0 (it) 1982-08-23
LV5621A3 (lv) 1994-05-10
ATA319182A (de) 1985-09-15
JPS5843975A (ja) 1983-03-14
SE8204817L (sv) 1983-02-25
FR2511679A1 (fr) 1983-02-25
NL990010I1 (nl) 1999-07-01
ES515176A0 (es) 1983-11-01
ES8400438A1 (es) 1983-11-01
AT380256B (de) 1986-05-12
DE19975037I2 (de) 2001-06-13
GR76863B (enExample) 1984-09-04
NZ201668A (en) 1985-08-16
AU8749382A (en) 1983-03-03
NL990010I2 (nl) 1999-09-01
FI822921L (fi) 1983-02-25
GB2104522A (en) 1983-03-09
IT1152505B (it) 1987-01-07
OA07174A (fr) 1984-04-30
IE822026L (en) 1983-02-24
DK161147C (da) 1991-11-18
FR2511679B1 (enExample) 1985-02-01
FI73434B (fi) 1987-06-30
NL192739C (nl) 1998-01-06
NL8203286A (nl) 1983-03-16
UA5971A1 (uk) 1994-12-29
LV5511A3 (lv) 1994-03-10
CH655114A5 (fr) 1986-03-27
DK161147B (da) 1991-06-03
LU84347A1 (fr) 1983-06-07
ZA826120B (en) 1983-07-27
GB2104522B (en) 1985-06-12
GEP19960641B (en) 1996-11-15
DK377882A (da) 1983-02-25
FI73434C (fi) 1987-10-09
IE53408B1 (en) 1988-11-09

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