SE437518B - Nya derivat av 4-amino-2-(piperazin-1-yl eller homopiperazin-1-yl)kinazolin, sett att framstella denna och farmaceutisk beredning for reglering av det kardiovaskulera systemet - Google Patents

Nya derivat av 4-amino-2-(piperazin-1-yl eller homopiperazin-1-yl)kinazolin, sett att framstella denna och farmaceutisk beredning for reglering av det kardiovaskulera systemet

Info

Publication number
SE437518B
SE437518B SE7811382A SE7811382A SE437518B SE 437518 B SE437518 B SE 437518B SE 7811382 A SE7811382 A SE 7811382A SE 7811382 A SE7811382 A SE 7811382A SE 437518 B SE437518 B SE 437518B
Authority
SE
Sweden
Prior art keywords
compound
benzodioxane
formula
chloroform
solution
Prior art date
Application number
SE7811382A
Other languages
English (en)
Swedish (sv)
Other versions
SE7811382L (sv
Inventor
S F Campbell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE7811382L publication Critical patent/SE7811382L/xx
Publication of SE437518B publication Critical patent/SE437518B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SE7811382A 1977-11-05 1978-11-02 Nya derivat av 4-amino-2-(piperazin-1-yl eller homopiperazin-1-yl)kinazolin, sett att framstella denna och farmaceutisk beredning for reglering av det kardiovaskulera systemet SE437518B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05

Publications (2)

Publication Number Publication Date
SE7811382L SE7811382L (sv) 1979-05-06
SE437518B true SE437518B (sv) 1985-03-04

Family

ID=10439957

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7811382A SE437518B (sv) 1977-11-05 1978-11-02 Nya derivat av 4-amino-2-(piperazin-1-yl eller homopiperazin-1-yl)kinazolin, sett att framstella denna och farmaceutisk beredning for reglering av det kardiovaskulera systemet

Country Status (36)

Country Link
JP (1) JPS5498792A (fr)
AR (2) AR219562A1 (fr)
AT (1) AT365186B (fr)
AU (1) AU509329B2 (fr)
BE (1) BE871771A (fr)
CA (1) CA1088059A (fr)
CH (1) CH643255A5 (fr)
CS (2) CS207671B2 (fr)
DD (1) DD139850A5 (fr)
DE (1) DE2847623C2 (fr)
DK (1) DK154082C (fr)
EG (1) EG13594A (fr)
ES (2) ES474805A1 (fr)
FI (1) FI64366C (fr)
FR (1) FR2407929A1 (fr)
GR (1) GR81514B (fr)
HK (1) HK94284A (fr)
HU (1) HU176306B (fr)
IE (1) IE47888B1 (fr)
IL (1) IL55857A (fr)
IN (1) IN148828B (fr)
IT (1) IT1100919B (fr)
KE (1) KE3350A (fr)
LU (2) LU80470A1 (fr)
MY (1) MY8500286A (fr)
NL (2) NL174549C (fr)
NO (1) NO150158C (fr)
NZ (1) NZ188813A (fr)
PH (1) PH13966A (fr)
PL (2) PL119586B1 (fr)
PT (1) PT68735A (fr)
SE (1) SE437518B (fr)
SU (1) SU816403A3 (fr)
UA (1) UA8324A1 (fr)
YU (2) YU40204B (fr)
ZA (1) ZA786184B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004658A1 (fr) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. Derives de 1,5 benzoxathiepine et leur preparation
WO1985002617A1 (fr) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. Derives de 1,5-benzoxathiepine et leur procede de preparation
WO1986002644A1 (fr) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. Derives de 1,5-benzoxathiepines et leur procede de preparation
EP0849264A1 (fr) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Nouvelle forme polymorphique de mésylate de doxazosin (forme I)
ES2282997T3 (es) * 1996-12-20 2007-10-16 Heumann Pcs Gmbh Nueva forma polimorfa de mesilato e doxazosina (forma iii).
EP0849265A1 (fr) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Nouvelle forme polymorphique de mésylate de doxazosin (forme II)
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (fr) * 2002-09-27 2005-06-22 Council of Scientific and Industrial Research Procédé pour la préparation de la N-(2,3-dihydrobenzo[1,4]dioxin-2-carbonyl)piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
AR223015A1 (es) 1981-07-15
DD139850A5 (de) 1980-01-23
IL55857A (en) 1982-07-30
NL174549B (nl) 1984-02-01
PL210681A1 (fr) 1979-11-05
IE782179L (en) 1979-05-05
IT7829434A0 (it) 1978-11-03
NL174549C (nl) 1984-07-02
IT1100919B (it) 1985-09-28
AR219562A1 (es) 1980-08-29
ES8308559A1 (es) 1980-07-16
CA1088059A (fr) 1980-10-21
NL930062I2 (nl) 1993-11-16
PT68735A (en) 1978-12-01
CH643255A5 (en) 1984-05-30
AU4132278A (en) 1979-05-17
NL7810909A (nl) 1979-05-08
LU80470A1 (fr) 1980-06-05
PL119419B1 (en) 1981-12-31
FI783347A (fi) 1979-05-06
NO150158B (no) 1984-05-21
JPS5498792A (en) 1979-08-03
LU88331I2 (fr) 1994-05-04
DK154082B (da) 1988-10-10
ZA786184B (en) 1979-10-31
FR2407929B1 (fr) 1981-02-27
FR2407929A1 (fr) 1979-06-01
YU40204B (en) 1985-08-31
NO783705L (no) 1979-05-08
NZ188813A (en) 1980-10-08
JPS5625233B2 (fr) 1981-06-11
AU509329B2 (en) 1980-05-08
YU38683A (en) 1983-06-30
MY8500286A (en) 1985-12-31
ES474805A1 (es) 1980-01-16
FI64366C (fi) 1983-11-10
AT365186B (de) 1981-12-28
PH13966A (en) 1980-11-12
IE47888B1 (en) 1984-07-11
IL55857A0 (en) 1979-01-31
HU176306B (en) 1981-01-28
EG13594A (en) 1982-03-31
NL930062I1 (nl) 1993-09-01
DE2847623C2 (de) 1983-06-01
DK428678A (da) 1979-05-06
BE871771A (fr) 1979-05-03
PL119586B1 (en) 1982-01-30
NO150158C (no) 1984-08-29
YU255378A (en) 1983-06-30
CS354491A3 (en) 1992-06-17
IN148828B (fr) 1981-06-27
HK94284A (en) 1984-12-07
CS207671B2 (en) 1981-08-31
GR81514B (fr) 1984-12-11
YU40419B (en) 1985-12-31
KE3350A (en) 1983-12-16
DK154082C (da) 1989-02-27
ES480121A0 (es) 1980-07-16
UA8324A1 (uk) 1996-03-29
FI64366B (fi) 1983-07-29
DE2847623A1 (de) 1979-05-23
ATA784378A (de) 1981-05-15
SE7811382L (sv) 1979-05-06
SU816403A3 (ru) 1981-03-23

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