AU509329B2 - Derivatives of 4-amino-2-(piperazin-1-yl or homopiperazin-1- yl) quinazoline - Google Patents

Derivatives of 4-amino-2-(piperazin-1-yl or homopiperazin-1- yl) quinazoline

Info

Publication number
AU509329B2
AU509329B2 AU41322/78A AU4132278A AU509329B2 AU 509329 B2 AU509329 B2 AU 509329B2 AU 41322/78 A AU41322/78 A AU 41322/78A AU 4132278 A AU4132278 A AU 4132278A AU 509329 B2 AU509329 B2 AU 509329B2
Authority
AU
Australia
Prior art keywords
homopiperazin
quinazoline
piperazin
derivatives
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU41322/78A
Other languages
English (en)
Other versions
AU4132278A (en
Inventor
Simon Fraser Campbell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Original Assignee
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp filed Critical Pfizer Corp
Publication of AU4132278A publication Critical patent/AU4132278A/en
Application granted granted Critical
Publication of AU509329B2 publication Critical patent/AU509329B2/en
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU41322/78A 1977-11-05 1978-11-03 Derivatives of 4-amino-2-(piperazin-1-yl or homopiperazin-1- yl) quinazoline Expired AU509329B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05
GBGB46,128/7 1977-11-05

Publications (2)

Publication Number Publication Date
AU4132278A AU4132278A (en) 1979-05-17
AU509329B2 true AU509329B2 (en) 1980-05-08

Family

ID=10439957

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41322/78A Expired AU509329B2 (en) 1977-11-05 1978-11-03 Derivatives of 4-amino-2-(piperazin-1-yl or homopiperazin-1- yl) quinazoline

Country Status (36)

Country Link
JP (1) JPS5498792A (fr)
AR (2) AR219562A1 (fr)
AT (1) AT365186B (fr)
AU (1) AU509329B2 (fr)
BE (1) BE871771A (fr)
CA (1) CA1088059A (fr)
CH (1) CH643255A5 (fr)
CS (2) CS207671B2 (fr)
DD (1) DD139850A5 (fr)
DE (1) DE2847623C2 (fr)
DK (1) DK154082C (fr)
EG (1) EG13594A (fr)
ES (2) ES474805A1 (fr)
FI (1) FI64366C (fr)
FR (1) FR2407929A1 (fr)
GR (1) GR81514B (fr)
HK (1) HK94284A (fr)
HU (1) HU176306B (fr)
IE (1) IE47888B1 (fr)
IL (1) IL55857A (fr)
IN (1) IN148828B (fr)
IT (1) IT1100919B (fr)
KE (1) KE3350A (fr)
LU (2) LU80470A1 (fr)
MY (1) MY8500286A (fr)
NL (2) NL174549C (fr)
NO (1) NO150158C (fr)
NZ (1) NZ188813A (fr)
PH (1) PH13966A (fr)
PL (2) PL119586B1 (fr)
PT (1) PT68735A (fr)
SE (1) SE437518B (fr)
SU (1) SU816403A3 (fr)
UA (1) UA8324A1 (fr)
YU (2) YU40204B (fr)
ZA (1) ZA786184B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004658A1 (fr) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. Derives de 1,5 benzoxathiepine et leur preparation
WO1985002617A1 (fr) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. Derives de 1,5-benzoxathiepine et leur procede de preparation
WO1986002644A1 (fr) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. Derives de 1,5-benzoxathiepines et leur procede de preparation
EP0849264A1 (fr) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Nouvelle forme polymorphique de mésylate de doxazosin (forme I)
ES2282997T3 (es) * 1996-12-20 2007-10-16 Heumann Pcs Gmbh Nueva forma polimorfa de mesilato e doxazosina (forma iii).
EP0849265A1 (fr) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Nouvelle forme polymorphique de mésylate de doxazosin (forme II)
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (fr) * 2002-09-27 2005-06-22 Council of Scientific and Industrial Research Procédé pour la préparation de la N-(2,3-dihydrobenzo[1,4]dioxin-2-carbonyl)piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
AR223015A1 (es) 1981-07-15
DD139850A5 (de) 1980-01-23
IL55857A (en) 1982-07-30
NL174549B (nl) 1984-02-01
PL210681A1 (fr) 1979-11-05
IE782179L (en) 1979-05-05
IT7829434A0 (it) 1978-11-03
NL174549C (nl) 1984-07-02
IT1100919B (it) 1985-09-28
AR219562A1 (es) 1980-08-29
ES8308559A1 (es) 1980-07-16
CA1088059A (fr) 1980-10-21
NL930062I2 (nl) 1993-11-16
PT68735A (en) 1978-12-01
CH643255A5 (en) 1984-05-30
AU4132278A (en) 1979-05-17
NL7810909A (nl) 1979-05-08
LU80470A1 (fr) 1980-06-05
PL119419B1 (en) 1981-12-31
FI783347A (fi) 1979-05-06
NO150158B (no) 1984-05-21
JPS5498792A (en) 1979-08-03
LU88331I2 (fr) 1994-05-04
DK154082B (da) 1988-10-10
ZA786184B (en) 1979-10-31
FR2407929B1 (fr) 1981-02-27
FR2407929A1 (fr) 1979-06-01
YU40204B (en) 1985-08-31
NO783705L (no) 1979-05-08
NZ188813A (en) 1980-10-08
JPS5625233B2 (fr) 1981-06-11
YU38683A (en) 1983-06-30
MY8500286A (en) 1985-12-31
ES474805A1 (es) 1980-01-16
FI64366C (fi) 1983-11-10
AT365186B (de) 1981-12-28
PH13966A (en) 1980-11-12
SE437518B (sv) 1985-03-04
IE47888B1 (en) 1984-07-11
IL55857A0 (en) 1979-01-31
HU176306B (en) 1981-01-28
EG13594A (en) 1982-03-31
NL930062I1 (nl) 1993-09-01
DE2847623C2 (de) 1983-06-01
DK428678A (da) 1979-05-06
BE871771A (fr) 1979-05-03
PL119586B1 (en) 1982-01-30
NO150158C (no) 1984-08-29
YU255378A (en) 1983-06-30
CS354491A3 (en) 1992-06-17
IN148828B (fr) 1981-06-27
HK94284A (en) 1984-12-07
CS207671B2 (en) 1981-08-31
GR81514B (fr) 1984-12-11
YU40419B (en) 1985-12-31
KE3350A (en) 1983-12-16
DK154082C (da) 1989-02-27
ES480121A0 (es) 1980-07-16
UA8324A1 (uk) 1996-03-29
FI64366B (fi) 1983-07-29
DE2847623A1 (de) 1979-05-23
ATA784378A (de) 1981-05-15
SE7811382L (sv) 1979-05-06
SU816403A3 (ru) 1981-03-23

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