SE407405B - Nya kromogena trombinsubstrat - Google Patents
Nya kromogena trombinsubstratInfo
- Publication number
- SE407405B SE407405B SE7507975-6A SE7507975A SE407405B SE 407405 B SE407405 B SE 407405B SE 7507975 A SE7507975 A SE 7507975A SE 407405 B SE407405 B SE 407405B
- Authority
- SE
- Sweden
- Prior art keywords
- chromogenate
- new
- thrombin substrate
- thrombin
- substrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/30—Naphthyl amides, e.g. beta-NA, 2-NA, 4-methoxy-beta-naphthylamine, i.e. 4MNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7507975-6A SE407405B (sv) | 1975-07-11 | 1975-07-11 | Nya kromogena trombinsubstrat |
ZA763586A ZA763586B (en) | 1975-07-11 | 1976-06-16 | Novel chromogenic thrombin substrates |
IL49829A IL49829A (en) | 1975-07-11 | 1976-06-17 | Chromogenic thrombin substrates |
US05/697,003 US4061625A (en) | 1975-07-11 | 1976-06-17 | Novel chromogenic thrombin substrates |
GB25580/76A GB1510926A (en) | 1975-07-11 | 1976-06-21 | Chromogenic thrombin substrates |
AU15305/76A AU497547B2 (en) | 1975-07-11 | 1976-06-25 | Chromogenic thrombin substrates |
AT463976A AT348686B (de) | 1975-07-11 | 1976-06-25 | Verahren zur bestimmung von thrombin und thrombinartigen enzymen durch spaltung chromogener substrate |
NLAANVRAGE7607104,A NL188355C (nl) | 1975-07-11 | 1976-06-29 | Werkwijze ter bereiding van chromogene thrombine-substraten. |
DE2629195A DE2629195C3 (de) | 1975-07-11 | 1976-06-29 | Tripeptide und deren Verwendung zur Bestimmung von Thrombin |
CA256,417A CA1068261A (fr) | 1975-07-11 | 1976-07-06 | Substrats chromogenes de type thrombine |
CS764544A CS196314B2 (en) | 1975-07-11 | 1976-07-08 | Process for preparing new chromogenous substrates specific especially for thrombine |
IT50364/76A IT1062605B (it) | 1975-07-11 | 1976-07-09 | Substrato cromogeno per trombine ed enzimi trombinici |
FR7621196A FR2317280A1 (fr) | 1975-07-11 | 1976-07-09 | Nouveaux substrats chromogenes pour la thrombine |
DK312676A DK145799C (da) | 1975-07-11 | 1976-07-09 | Tripeptider eller salte deraf til anvendelse som diagnostisk kromogent substrat med hoej specificitet overfor thrombin og thrombinlignende enzymer |
SU762379659A SU719492A3 (ru) | 1975-07-11 | 1976-07-09 | Способ получени пептидов или их солей |
PL1976191068A PL103003B1 (pl) | 1975-07-11 | 1976-07-09 | Sposob wytwarzania nowych chromogennych odczynnikow do oznaczania trombiny i podobnych do trombiny enzymow |
BE168774A BE843970A (fr) | 1975-07-11 | 1976-07-09 | Nouveaux substrats chromogenes de thrombine |
NO762407A NO142576C (no) | 1975-07-11 | 1976-07-09 | Nye diagnostisk aktive kromogene substrater med hoey spesifisitet for thrombin og thrombinlignende ensymer |
FI762010A FI56525C (fi) | 1975-07-11 | 1976-07-09 | Nya kromogena trombinsubstrat |
ES449739A ES449739A1 (es) | 1975-07-11 | 1976-07-09 | Procedimiento de obtencion de nuevos sustratos cronogenicos para trombina. |
DD7600193785A DD128691A5 (de) | 1975-07-11 | 1976-07-09 | Neue chromogensubstrate fuer thrombin |
CH887476A CH622287A5 (en) | 1975-07-11 | 1976-07-09 | Method for the determination of thrombin or of enzymes which cleave the substrates in the same way as thrombin, and use of the method |
JP51082442A JPS5224590A (en) | 1975-07-11 | 1976-07-10 | Colorrgenerating new thrombin substrae |
US05/826,594 US4169015A (en) | 1975-07-11 | 1977-08-22 | Novel chromogenic thrombin substrates |
US06/055,664 US4247454A (en) | 1975-07-11 | 1979-07-09 | Novel chromogenic thrombin substrates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7507975-6A SE407405B (sv) | 1975-07-11 | 1975-07-11 | Nya kromogena trombinsubstrat |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7507975L SE7507975L (sv) | 1977-01-12 |
SE407405B true SE407405B (sv) | 1979-03-26 |
Family
ID=20325116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7507975-6A SE407405B (sv) | 1975-07-11 | 1975-07-11 | Nya kromogena trombinsubstrat |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS5224590A (fr) |
AT (1) | AT348686B (fr) |
AU (1) | AU497547B2 (fr) |
BE (1) | BE843970A (fr) |
CA (1) | CA1068261A (fr) |
CH (1) | CH622287A5 (fr) |
CS (1) | CS196314B2 (fr) |
DD (1) | DD128691A5 (fr) |
DE (1) | DE2629195C3 (fr) |
DK (1) | DK145799C (fr) |
ES (1) | ES449739A1 (fr) |
FI (1) | FI56525C (fr) |
FR (1) | FR2317280A1 (fr) |
GB (1) | GB1510926A (fr) |
IL (1) | IL49829A (fr) |
IT (1) | IT1062605B (fr) |
NL (1) | NL188355C (fr) |
NO (1) | NO142576C (fr) |
PL (1) | PL103003B1 (fr) |
SE (1) | SE407405B (fr) |
SU (1) | SU719492A3 (fr) |
ZA (1) | ZA763586B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5255593A (en) * | 1975-10-30 | 1977-05-07 | Ajinomoto Kk | Measuring method of enzyme activity |
DE2757992A1 (de) * | 1977-12-24 | 1979-06-28 | Boehringer Mannheim Gmbh | Verfahren zur prothrombin-bestimmung |
DE2812943C3 (de) * | 1978-03-23 | 1981-05-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Reagens zur Bestimmung der biologischen Aktivität von Heparin im Plasma |
US4289498A (en) * | 1979-01-08 | 1981-09-15 | Ortho Diagnostics, Inc. | One-stage prothrombin assay and compositions useful therein |
FR2471410A2 (fr) * | 1979-12-17 | 1981-06-19 | Jozefonvicz Marcel | Perfectionnements apportes a un procede de dosage des proteases et des anti-proteases et notamment des proteases et antiproteases des systemes de la coagulation et du complement |
DE3061860D1 (en) * | 1979-04-24 | 1983-03-17 | Marcel Jozefonvicz | Process for the determination of proteases and antiproteases |
DE3005540A1 (de) * | 1980-02-14 | 1981-08-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagens zur bestimmung der biologischen aktivitaet von heparin im plasma |
DK155051C (da) * | 1980-05-06 | 1989-07-03 | Pentapharm Ag | Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf |
JPS5856695A (ja) * | 1981-09-28 | 1983-04-04 | Nitto Boseki Co Ltd | 新規なトロンビン測定用基質 |
DE3211254A1 (de) * | 1982-03-26 | 1983-09-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zum nachweis des vorliegens einer allergie und zum spezifischen nachweis des fuer die allergie verantwortlichen allergens |
DK201084A (da) * | 1983-04-28 | 1984-10-29 | Kimberly Clark Co | Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden |
CN101180405A (zh) | 2005-05-20 | 2008-05-14 | 株式会社三菱化学药得论 | 酶分析方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE380258B (sv) * | 1972-05-02 | 1975-11-03 | Bofors Ab | Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser |
SE380257B (sv) * | 1972-05-02 | 1975-11-03 | Bofors Ab | Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser |
-
1975
- 1975-07-11 SE SE7507975-6A patent/SE407405B/xx not_active IP Right Cessation
-
1976
- 1976-06-16 ZA ZA763586A patent/ZA763586B/xx unknown
- 1976-06-17 IL IL49829A patent/IL49829A/xx unknown
- 1976-06-21 GB GB25580/76A patent/GB1510926A/en not_active Expired
- 1976-06-25 AT AT463976A patent/AT348686B/de not_active IP Right Cessation
- 1976-06-25 AU AU15305/76A patent/AU497547B2/en not_active Expired
- 1976-06-29 DE DE2629195A patent/DE2629195C3/de not_active Expired
- 1976-06-29 NL NLAANVRAGE7607104,A patent/NL188355C/xx not_active IP Right Cessation
- 1976-07-06 CA CA256,417A patent/CA1068261A/fr not_active Expired
- 1976-07-08 CS CS764544A patent/CS196314B2/cs unknown
- 1976-07-09 SU SU762379659A patent/SU719492A3/ru active
- 1976-07-09 BE BE168774A patent/BE843970A/fr not_active IP Right Cessation
- 1976-07-09 PL PL1976191068A patent/PL103003B1/pl unknown
- 1976-07-09 FI FI762010A patent/FI56525C/fi not_active IP Right Cessation
- 1976-07-09 CH CH887476A patent/CH622287A5/de not_active IP Right Cessation
- 1976-07-09 DK DK312676A patent/DK145799C/da not_active IP Right Cessation
- 1976-07-09 IT IT50364/76A patent/IT1062605B/it active
- 1976-07-09 ES ES449739A patent/ES449739A1/es not_active Expired
- 1976-07-09 NO NO762407A patent/NO142576C/no unknown
- 1976-07-09 DD DD7600193785A patent/DD128691A5/xx unknown
- 1976-07-09 FR FR7621196A patent/FR2317280A1/fr active Granted
- 1976-07-10 JP JP51082442A patent/JPS5224590A/ja active Granted
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Legal Events
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NUG | Patent has lapsed |
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