ZA763586B - Novel chromogenic thrombin substrates - Google Patents
Novel chromogenic thrombin substratesInfo
- Publication number
- ZA763586B ZA763586B ZA763586A ZA763586A ZA763586B ZA 763586 B ZA763586 B ZA 763586B ZA 763586 A ZA763586 A ZA 763586A ZA 763586 A ZA763586 A ZA 763586A ZA 763586 B ZA763586 B ZA 763586B
- Authority
- ZA
- South Africa
- Prior art keywords
- thrombin substrates
- chromogenic thrombin
- novel chromogenic
- novel
- substrates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/30—Naphthyl amides, e.g. beta-NA, 2-NA, 4-methoxy-beta-naphthylamine, i.e. 4MNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7507975-6A SE407405B (en) | 1975-07-11 | 1975-07-11 | NEW CHROMOGENATE THROMBIN SUBSTRATE |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA763586B true ZA763586B (en) | 1977-05-25 |
Family
ID=20325116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA763586A ZA763586B (en) | 1975-07-11 | 1976-06-16 | Novel chromogenic thrombin substrates |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS5224590A (en) |
AT (1) | AT348686B (en) |
AU (1) | AU497547B2 (en) |
BE (1) | BE843970A (en) |
CA (1) | CA1068261A (en) |
CH (1) | CH622287A5 (en) |
CS (1) | CS196314B2 (en) |
DD (1) | DD128691A5 (en) |
DE (1) | DE2629195C3 (en) |
DK (1) | DK145799C (en) |
ES (1) | ES449739A1 (en) |
FI (1) | FI56525C (en) |
FR (1) | FR2317280A1 (en) |
GB (1) | GB1510926A (en) |
IL (1) | IL49829A (en) |
IT (1) | IT1062605B (en) |
NL (1) | NL188355C (en) |
NO (1) | NO142576C (en) |
PL (1) | PL103003B1 (en) |
SE (1) | SE407405B (en) |
SU (1) | SU719492A3 (en) |
ZA (1) | ZA763586B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5255593A (en) * | 1975-10-30 | 1977-05-07 | Ajinomoto Kk | Measuring method of enzyme activity |
DE2757992A1 (en) * | 1977-12-24 | 1979-06-28 | Boehringer Mannheim Gmbh | METHOD FOR PROTHROMBIN DETERMINATION |
DE2812943C3 (en) * | 1978-03-23 | 1981-05-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Method and reagent for determining the biological activity of heparin in plasma |
US4289498A (en) * | 1979-01-08 | 1981-09-15 | Ortho Diagnostics, Inc. | One-stage prothrombin assay and compositions useful therein |
FR2471410A2 (en) * | 1979-12-17 | 1981-06-19 | Jozefonvicz Marcel | Electrochemical protease or anti-protease determn. - by amperometric determn. of amine released from peptide amide substrate |
EP0018002B1 (en) * | 1979-04-24 | 1983-02-09 | Marcel Jozefonvicz | Process for the determination of proteases and antiproteases |
DE3005540A1 (en) * | 1980-02-14 | 1981-08-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD AND REAGENT FOR DETERMINING THE BIOLOGICAL ACTIVITY OF HEPARIN IN PLASMA |
DK155051C (en) * | 1980-05-06 | 1989-07-03 | Pentapharm Ag | TRIPEPTIDE DERIVATIVES AND PROCEDURES FOR QUANTITATIVE ANALYSIS OF PROTEOLYTIC ENZYMES UNDER USE thereof |
JPS5856695A (en) * | 1981-09-28 | 1983-04-04 | Nitto Boseki Co Ltd | Novel substrate for assay of thrombin |
DE3211254A1 (en) * | 1982-03-26 | 1983-09-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD FOR DETECTING THE PRESENCE OF AN ALLERGY AND FOR SPECIFIC DETECTING THE ALLERGY RESPONSIBLE FOR THE ALLERGY |
DK201084A (en) * | 1983-04-28 | 1984-10-29 | Kimberly Clark Co | PROCEDURE FOR DETERMINING CATHEPSIN B IN THE PRESENCE OF OTHER PROTEOLYTIC ENZYMES AND RELATIONSHIPS FOR USING THE PROCEDURE |
CA2609113A1 (en) | 2005-05-20 | 2006-11-23 | Mitsubishi Kagaku Iatron, Inc. | Method of analyzing enzyme |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE380257B (en) * | 1972-05-02 | 1975-11-03 | Bofors Ab | NEW DIAGNOSTIC OPERATING SUBSTRATES WITH HIGH SPECIFICITY FOR THROMBIN AND OTHER PROTEOLYTIC ENZYMES OF THE PEPTIDYL-PEPTIDE HYDROLASES |
IL42124A (en) * | 1972-05-02 | 1977-02-28 | Kabi Ab | Substrate for the determination of proteolytic enzymes |
-
1975
- 1975-07-11 SE SE7507975-6A patent/SE407405B/en not_active IP Right Cessation
-
1976
- 1976-06-16 ZA ZA763586A patent/ZA763586B/en unknown
- 1976-06-17 IL IL49829A patent/IL49829A/en unknown
- 1976-06-21 GB GB25580/76A patent/GB1510926A/en not_active Expired
- 1976-06-25 AU AU15305/76A patent/AU497547B2/en not_active Expired
- 1976-06-25 AT AT463976A patent/AT348686B/en not_active IP Right Cessation
- 1976-06-29 NL NLAANVRAGE7607104,A patent/NL188355C/en not_active IP Right Cessation
- 1976-06-29 DE DE2629195A patent/DE2629195C3/en not_active Expired
- 1976-07-06 CA CA256,417A patent/CA1068261A/en not_active Expired
- 1976-07-08 CS CS764544A patent/CS196314B2/en unknown
- 1976-07-09 IT IT50364/76A patent/IT1062605B/en active
- 1976-07-09 NO NO762407A patent/NO142576C/en unknown
- 1976-07-09 CH CH887476A patent/CH622287A5/en not_active IP Right Cessation
- 1976-07-09 DK DK312676A patent/DK145799C/en not_active IP Right Cessation
- 1976-07-09 SU SU762379659A patent/SU719492A3/en active
- 1976-07-09 BE BE168774A patent/BE843970A/en not_active IP Right Cessation
- 1976-07-09 PL PL1976191068A patent/PL103003B1/en unknown
- 1976-07-09 FI FI762010A patent/FI56525C/en not_active IP Right Cessation
- 1976-07-09 ES ES449739A patent/ES449739A1/en not_active Expired
- 1976-07-09 DD DD7600193785A patent/DD128691A5/en unknown
- 1976-07-09 FR FR7621196A patent/FR2317280A1/en active Granted
- 1976-07-10 JP JP51082442A patent/JPS5224590A/en active Granted
Also Published As
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