JPS5224590A - Colorrgenerating new thrombin substrae - Google Patents
Colorrgenerating new thrombin substraeInfo
- Publication number
- JPS5224590A JPS5224590A JP51082442A JP8244276A JPS5224590A JP S5224590 A JPS5224590 A JP S5224590A JP 51082442 A JP51082442 A JP 51082442A JP 8244276 A JP8244276 A JP 8244276A JP S5224590 A JPS5224590 A JP S5224590A
- Authority
- JP
- Japan
- Prior art keywords
- colorrgenerating
- substrae
- new thrombin
- thrombin
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/30—Naphthyl amides, e.g. beta-NA, 2-NA, 4-methoxy-beta-naphthylamine, i.e. 4MNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7507975-6A SE407405B (en) | 1975-07-11 | 1975-07-11 | NEW CHROMOGENATE THROMBIN SUBSTRATE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5224590A true JPS5224590A (en) | 1977-02-24 |
| JPS5615239B2 JPS5615239B2 (en) | 1981-04-09 |
Family
ID=20325116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51082442A Granted JPS5224590A (en) | 1975-07-11 | 1976-07-10 | Colorrgenerating new thrombin substrae |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5224590A (en) |
| AT (1) | AT348686B (en) |
| AU (1) | AU497547B2 (en) |
| BE (1) | BE843970A (en) |
| CA (1) | CA1068261A (en) |
| CH (1) | CH622287A5 (en) |
| CS (1) | CS196314B2 (en) |
| DD (1) | DD128691A5 (en) |
| DE (1) | DE2629195C3 (en) |
| DK (1) | DK145799C (en) |
| ES (1) | ES449739A1 (en) |
| FI (1) | FI56525C (en) |
| FR (1) | FR2317280A1 (en) |
| GB (1) | GB1510926A (en) |
| IL (1) | IL49829A (en) |
| IT (1) | IT1062605B (en) |
| NL (1) | NL188355C (en) |
| NO (1) | NO142576C (en) |
| PL (1) | PL103003B1 (en) |
| SE (1) | SE407405B (en) |
| SU (1) | SU719492A3 (en) |
| ZA (1) | ZA763586B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5492393A (en) * | 1977-12-24 | 1979-07-21 | Boehringer Mannheim Gmbh | Method and reagent for measuring prothrombin and production of xa factor preparation |
| WO2006123789A1 (en) | 2005-05-20 | 2006-11-23 | Mitsubishi Kagaku Iatron, Inc. | Method of analyzing enzyme |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5255593A (en) * | 1975-10-30 | 1977-05-07 | Ajinomoto Kk | Measuring method of enzyme activity |
| DE2812943C3 (en) * | 1978-03-23 | 1981-05-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Method and reagent for determining the biological activity of heparin in plasma |
| US4289498A (en) * | 1979-01-08 | 1981-09-15 | Ortho Diagnostics, Inc. | One-stage prothrombin assay and compositions useful therein |
| FR2471410A2 (en) * | 1979-12-17 | 1981-06-19 | Jozefonvicz Marcel | Electrochemical protease or anti-protease determn. - by amperometric determn. of amine released from peptide amide substrate |
| EP0018002B1 (en) * | 1979-04-24 | 1983-02-09 | Marcel Jozefonvicz | Process for the determination of proteases and antiproteases |
| DE3005540A1 (en) * | 1980-02-14 | 1981-08-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD AND REAGENT FOR DETERMINING THE BIOLOGICAL ACTIVITY OF HEPARIN IN PLASMA |
| DK155051C (en) * | 1980-05-06 | 1989-07-03 | Pentapharm Ag | TRIPEPTIDE DERIVATIVES AND PROCEDURES FOR QUANTITATIVE ANALYSIS OF PROTEOLYTIC ENZYMES UNDER USE thereof |
| JPS5856695A (en) * | 1981-09-28 | 1983-04-04 | Nitto Boseki Co Ltd | Novel substrate for assay of thrombin |
| DE3211254A1 (en) * | 1982-03-26 | 1983-09-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD FOR DETECTING THE PRESENCE OF AN ALLERGY AND FOR SPECIFIC DETECTING THE ALLERGY RESPONSIBLE FOR THE ALLERGY |
| DK201084A (en) * | 1983-04-28 | 1984-10-29 | Kimberly Clark Co | PROCEDURE FOR DETERMINING CATHEPSIN B IN THE PRESENCE OF OTHER PROTEOLYTIC ENZYMES AND RELATIONSHIPS FOR USING THE PROCEDURE |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4949695A (en) * | 1972-05-02 | 1974-05-14 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE380258B (en) * | 1972-05-02 | 1975-11-03 | Bofors Ab | NEW DIAGNOSTIC OPERATING SUBSIDIES WITH HIGH SPECIFICITY FOR TRYPSIN AND OTHER PEPTIDYL-PEPTIDE HYDROLASES OF THE PEPTIDYL TYPE |
-
1975
- 1975-07-11 SE SE7507975-6A patent/SE407405B/en not_active IP Right Cessation
-
1976
- 1976-06-16 ZA ZA763586A patent/ZA763586B/en unknown
- 1976-06-17 IL IL49829A patent/IL49829A/en unknown
- 1976-06-21 GB GB25580/76A patent/GB1510926A/en not_active Expired
- 1976-06-25 AT AT463976A patent/AT348686B/en not_active IP Right Cessation
- 1976-06-25 AU AU15305/76A patent/AU497547B2/en not_active Expired
- 1976-06-29 DE DE2629195A patent/DE2629195C3/en not_active Expired
- 1976-06-29 NL NLAANVRAGE7607104,A patent/NL188355C/en not_active IP Right Cessation
- 1976-07-06 CA CA256,417A patent/CA1068261A/en not_active Expired
- 1976-07-08 CS CS764544A patent/CS196314B2/en unknown
- 1976-07-09 DD DD7600193785A patent/DD128691A5/en unknown
- 1976-07-09 BE BE168774A patent/BE843970A/en not_active IP Right Cessation
- 1976-07-09 FR FR7621196A patent/FR2317280A1/en active Granted
- 1976-07-09 CH CH887476A patent/CH622287A5/en not_active IP Right Cessation
- 1976-07-09 SU SU762379659A patent/SU719492A3/en active
- 1976-07-09 PL PL1976191068A patent/PL103003B1/en unknown
- 1976-07-09 DK DK312676A patent/DK145799C/en not_active IP Right Cessation
- 1976-07-09 NO NO762407A patent/NO142576C/en unknown
- 1976-07-09 IT IT50364/76A patent/IT1062605B/en active
- 1976-07-09 FI FI762010A patent/FI56525C/en not_active IP Right Cessation
- 1976-07-09 ES ES449739A patent/ES449739A1/en not_active Expired
- 1976-07-10 JP JP51082442A patent/JPS5224590A/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4949695A (en) * | 1972-05-02 | 1974-05-14 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5492393A (en) * | 1977-12-24 | 1979-07-21 | Boehringer Mannheim Gmbh | Method and reagent for measuring prothrombin and production of xa factor preparation |
| JPS588840B2 (en) * | 1977-12-24 | 1983-02-17 | ベ−リンガ−・マンハイム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | How to measure prothrombin |
| WO2006123789A1 (en) | 2005-05-20 | 2006-11-23 | Mitsubishi Kagaku Iatron, Inc. | Method of analyzing enzyme |
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