SE0400501D0 - Antibody purification - Google Patents
Antibody purificationInfo
- Publication number
- SE0400501D0 SE0400501D0 SE0400501A SE0400501A SE0400501D0 SE 0400501 D0 SE0400501 D0 SE 0400501D0 SE 0400501 A SE0400501 A SE 0400501A SE 0400501 A SE0400501 A SE 0400501A SE 0400501 D0 SE0400501 D0 SE 0400501D0
- Authority
- SE
- Sweden
- Prior art keywords
- cation
- aromatic
- solution
- modal
- exchanging group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3847—Multimodal interactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
- B01J39/07—Processes using organic exchangers in the weakly acidic form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J47/00—Ion-exchange processes in general; Apparatus therefor
- B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Priority Applications (23)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0400501A SE0400501D0 (sv) | 2004-02-27 | 2004-02-27 | Antibody purification |
PCT/SE2005/000292 WO2005082926A1 (en) | 2004-02-27 | 2005-02-24 | Antibody purification |
EP05722174A EP1718668B1 (en) | 2004-02-27 | 2005-02-24 | Antibody purification |
AU2005217348A AU2005217348B2 (en) | 2004-02-27 | 2005-02-24 | Antibody purification |
JP2007500724A JP4776615B2 (ja) | 2004-02-27 | 2005-02-24 | 抗体精製 |
KR1020067017115A KR101149969B1 (ko) | 2004-02-27 | 2005-02-24 | 항체 정제 |
CN2005800062670A CN1926146B (zh) | 2004-02-27 | 2005-02-24 | 抗体纯化 |
CA2552823A CA2552823C (en) | 2004-02-27 | 2005-02-24 | Antibody purification |
AT05722174T ATE440858T1 (de) | 2004-02-27 | 2005-02-24 | Aufreinigung von antikírpern |
US10/589,718 US7385040B2 (en) | 2004-02-27 | 2005-02-24 | Antibody purification |
NZ548127A NZ548127A (en) | 2004-02-27 | 2005-02-24 | Method for antibody purification |
DE602005016220T DE602005016220D1 (de) | 2004-02-27 | 2005-02-24 | Aufreinigung von antikörpern |
EP05722175A EP1718386A1 (en) | 2004-02-27 | 2005-02-25 | A process for the purification of antibodies |
US10/589,717 US7750129B2 (en) | 2004-02-27 | 2005-02-25 | Process for the purification of antibodies |
JP2007500725A JP4848356B2 (ja) | 2004-02-27 | 2005-02-25 | 抗体精製法 |
NZ548126A NZ548126A (en) | 2004-02-27 | 2005-02-25 | A process for the purification of antibodies involving addition of a second resin |
CN200580006276XA CN1925898B (zh) | 2004-02-27 | 2005-02-25 | 纯化抗体的工艺 |
PCT/SE2005/000293 WO2005082483A1 (en) | 2004-02-27 | 2005-02-25 | A process for the purification of antibodies |
AU2005216847A AU2005216847B2 (en) | 2004-02-27 | 2005-02-25 | A process for the purification of antibodies |
KR1020067017113A KR101150050B1 (ko) | 2004-02-27 | 2005-02-25 | 항체 정제 방법 |
CA2552639A CA2552639C (en) | 2004-02-27 | 2005-02-25 | A process for the purification of antibodies |
IL176635A IL176635A (en) | 2004-02-27 | 2006-06-29 | Method of purification of antibodies from one or more contaminants by chromatography and a system for such purification |
IL176745A IL176745A (en) | 2004-02-27 | 2006-07-06 | Process for the purification of antibodies |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0400501A SE0400501D0 (sv) | 2004-02-27 | 2004-02-27 | Antibody purification |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0400501D0 true SE0400501D0 (sv) | 2004-02-27 |
Family
ID=32067281
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0400501A SE0400501D0 (sv) | 2004-02-27 | 2004-02-27 | Antibody purification |
Country Status (13)
Country | Link |
---|---|
US (1) | US7385040B2 (ko) |
EP (1) | EP1718668B1 (ko) |
JP (1) | JP4776615B2 (ko) |
KR (1) | KR101149969B1 (ko) |
CN (2) | CN1926146B (ko) |
AT (1) | ATE440858T1 (ko) |
AU (1) | AU2005217348B2 (ko) |
CA (1) | CA2552823C (ko) |
DE (1) | DE602005016220D1 (ko) |
IL (1) | IL176635A (ko) |
NZ (1) | NZ548127A (ko) |
SE (1) | SE0400501D0 (ko) |
WO (1) | WO2005082926A1 (ko) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160279239A1 (en) | 2011-05-02 | 2016-09-29 | Immunomedics, Inc. | Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease |
US20160355591A1 (en) | 2011-05-02 | 2016-12-08 | Immunomedics, Inc. | Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies |
US7589183B2 (en) * | 2006-11-28 | 2009-09-15 | Bio-Rad Laboratories, Inc. | Prevention of leaching of ligands from affinity-based purification systems |
US7691980B2 (en) | 2007-01-09 | 2010-04-06 | Bio-Rad Laboratories, Inc. | Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers |
US7999085B2 (en) * | 2007-01-09 | 2011-08-16 | Bio-Rad Laboratories, Inc. | Enhanced capacity and purification of protein by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers |
WO2008085116A1 (en) * | 2007-01-10 | 2008-07-17 | Ge Healthcare Bio-Sciences Ab | Mult i -modal ion exchange chromotography resins |
CA2682333C (en) | 2007-03-28 | 2015-05-05 | Upfront Chromatography A/S | Expanded bed column and disposable chromatography |
KR101226353B1 (ko) * | 2007-06-01 | 2013-01-24 | 에프. 호프만-라 로슈 아게 | 면역글로불린 정제 |
US9433922B2 (en) * | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
EP2027875A1 (en) | 2007-08-23 | 2009-02-25 | Octapharma AG | A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC) |
EP2226331A4 (en) | 2007-10-26 | 2012-02-08 | Asahi Kasei Chemicals Corp | METHOD OF PURIFYING PROTEINS |
US8158405B2 (en) * | 2008-06-30 | 2012-04-17 | General Electric Company | Process for concentrating and processing fluid samples |
US8546127B2 (en) * | 2008-06-30 | 2013-10-01 | General Electric Company | Bacteria/RNA extraction device |
US8753868B2 (en) | 2008-08-04 | 2014-06-17 | General Electric Company | Method and system for selective isolation of target biological molecules in a general purpose system |
US20100051554A1 (en) * | 2008-08-28 | 2010-03-04 | Dong June Ahn | Molecular basket coated micro particles |
WO2010071208A1 (ja) * | 2008-12-19 | 2010-06-24 | 武田薬品工業株式会社 | 抗体の精製方法 |
CN101797493B (zh) * | 2009-02-06 | 2014-05-21 | 上海抗体药物国家工程研究中心有限公司 | 一种在反应釜中制备亲和层析介质的方法 |
DE102009057993A1 (de) | 2009-06-13 | 2011-01-20 | Sartorius Stedim Biotech Gmbh | Polysaccharidmatrix mit aufgepfropftem Polymer, Verfahren zu ihrer Herstellung und Verwendung |
WO2011001963A1 (ja) * | 2009-07-03 | 2011-01-06 | 旭化成ケミカルズ株式会社 | 多孔質基材に固定されたグラフト鎖に結合しているアミノ基及びアルキル基を有する多孔膜を用いた抗体の精製方法 |
US20120208986A1 (en) * | 2009-10-20 | 2012-08-16 | Wenger Marc D | Use of mixed mode chromatography for the capture and purification of basic antibody products |
US8277649B2 (en) * | 2009-12-14 | 2012-10-02 | General Electric Company | Membranes and associated methods for purification of antibodies |
WO2011090719A2 (en) * | 2009-12-29 | 2011-07-28 | Dr. Reddy's Laboratories Ltd. | Protein purification by ion exchange |
KR101152036B1 (ko) | 2010-04-27 | 2012-06-08 | (주)셀트리온 | 컬럼 순환 및 시료 연속주입법을 이용한 단백질 a 크로마토그래피 정제 방법 |
EP2598223B1 (en) | 2010-07-30 | 2022-04-06 | EMD Millipore Corporation | Chromatography media and method |
CA2831572C (en) | 2011-05-02 | 2019-11-26 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
EP2726496B1 (en) | 2011-07-01 | 2018-04-04 | F.Hoffmann-La Roche Ag | Method for separation of monomeric polypeptides from aggregated polypeptides |
CN103906762A (zh) * | 2011-10-26 | 2014-07-02 | 生物辐射实验室股份有限公司 | 在混合式层析中去除杀病毒剂 |
GB201202762D0 (en) | 2012-02-17 | 2012-04-04 | Autology Health Ltd | High efficiency cell capture |
CN103506079B (zh) * | 2012-06-19 | 2016-04-06 | 汪志友 | 一种用于分离纯化抗体的介质及其制备方法 |
JP6335785B2 (ja) * | 2012-09-03 | 2018-05-30 | 株式会社カネカ | ミックスモード抗体アフィニティー分離マトリックスとそれを用いた精製方法および標的分子 |
KR102196230B1 (ko) | 2012-09-17 | 2020-12-29 | 더블유.알. 그레이스 앤드 캄파니-콘. | 크로마토그래피 매질 및 장치 |
US11718643B2 (en) | 2012-11-13 | 2023-08-08 | Cytiva Bioprocess R&D Ab | Multimodal anion exchange matrices |
JP6639236B2 (ja) | 2013-02-26 | 2020-02-05 | ナトリックス セパレイションズ インコーポレーテッド | 混合モードクロマトグラフィー膜 |
TWI596107B (zh) | 2013-06-25 | 2017-08-21 | 卡地拉保健有限公司 | 單株抗體之新穎純化方法 |
CN105555795A (zh) * | 2013-09-17 | 2016-05-04 | 株式会社钟化 | 新抗体纯化方法和由该方法得到的抗体、以及使用了阳离子交换基团的新抗体纯化法和由该方法得到的抗体 |
RU2016123146A (ru) * | 2013-11-17 | 2017-12-21 | Нью Протеинтек Инк. | Способ получения хроматографических материалов |
ES2887110T3 (es) | 2014-01-16 | 2021-12-21 | Grace W R & Co | Medios para cromatografía de afinidad y dispositivos para cromatografía |
PL3137209T3 (pl) | 2014-05-02 | 2023-01-02 | W.R. Grace & Co. - Conn. | Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego |
DE102014010353A1 (de) | 2014-07-10 | 2016-01-14 | Sartorius Stedim Biotech Gmbh | Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien |
JP6437553B2 (ja) | 2014-07-25 | 2018-12-12 | 旭化成メディカル株式会社 | 陽イオン交換クロマトグラフィー担体及びその使用方法 |
HUE045466T2 (hu) | 2014-11-06 | 2019-12-30 | Hoffmann La Roche | Fc-régió-variánsok módosított FcRn-kötéssel és alkalmazási eljárások |
EP3230299A1 (en) | 2014-12-08 | 2017-10-18 | EMD Millipore Corporation | Mixed bed ion exchange adsorber |
ES2896897T3 (es) | 2015-06-05 | 2022-02-28 | Grace W R & Co | Agentes de clarificación para el bioprocesamiento de adsorbentes y métodos para producir y usar los mismos |
JP2019070528A (ja) * | 2016-02-26 | 2019-05-09 | Jsr株式会社 | 多孔質担体、アフィニティクロマトグラフィー用多孔質担体、標的物の精製方法、及び抗体 |
EP3448564B1 (en) * | 2016-04-29 | 2021-06-09 | Creoptix AG | Methods and assemblies for molecule recovery |
EP3500297A1 (en) | 2016-08-16 | 2019-06-26 | Regeneron Pharmaceuticals, Inc. | Methods for quantitating individual antibodies from a mixture |
DK3532838T3 (da) | 2016-10-25 | 2022-07-04 | Regeneron Pharma | Fremgangsmåder og systemer til kromatografidataanalyse |
EP3606964A4 (en) | 2017-04-03 | 2020-12-09 | Immunomedics, Inc. | SUBCUTANE ADMINISTRATION OF ANTIBODY DRUG CONJUGATES FOR CANCER THERAPY |
IL272954B2 (en) | 2017-09-19 | 2024-06-01 | Regeneron Pharma | Methods to reduce the generation of particles and preparations created by them |
CN115318256A (zh) * | 2018-03-08 | 2022-11-11 | 生物辐射实验室股份有限公司 | 阴离子交换-疏水混合模式色谱树脂 |
US11155575B2 (en) | 2018-03-21 | 2021-10-26 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbent, devices and methods |
WO2020004583A1 (ja) * | 2018-06-29 | 2020-01-02 | 三菱ケミカル株式会社 | ポリペプチドの分離方法、ポリペプチドの製造方法及びポリペプチドの精製装置 |
TW202005694A (zh) | 2018-07-02 | 2020-02-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
EP4025336A4 (en) | 2019-09-05 | 2024-01-17 | Bio-Rad Laboratories, Inc. | ANION EXCHANGE/HYDROPHOBIC RESINS FOR MIXED MODE CHROMATOGRAPHY |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE462046C (sv) | 1982-08-23 | 1998-04-27 | Pharmacia Biotech Ab | Hybrid-DNA-vektor innehållande DNA-sekvens från Staphylococcus aureus, förfarande för dess framställning och bakterie innehållande densamma |
US5151350A (en) * | 1982-10-27 | 1992-09-29 | Repligen Corporation | Cloned genes encoding recombinant protein a |
US4983722A (en) | 1988-06-08 | 1991-01-08 | Miles Inc. | Removal of protein A from antibody preparations |
US5429746A (en) * | 1994-02-22 | 1995-07-04 | Smith Kline Beecham Corporation | Antibody purification |
US6117996A (en) * | 1995-09-20 | 2000-09-12 | Novo Nordisk A/S | Triazine based ligands and use thereof |
GB9519197D0 (en) * | 1995-09-20 | 1995-11-22 | Affinity Chromatography Ltd | Novel affinity ligands and their use |
DE69726285T2 (de) * | 1996-08-30 | 2004-09-09 | Upfront Chromatography A/S, Kopenhagen | Isolierung von immunglobulinen |
SE0002688D0 (sv) | 2000-07-17 | 2000-07-17 | Amersham Pharm Biotech Ab | Adsorption method and ligands |
US6852230B2 (en) * | 2000-12-31 | 2005-02-08 | Amersham Biosciences Ab | Method for the manufacture of compositions containing low concentrations of salts |
US20020110495A1 (en) * | 2001-01-05 | 2002-08-15 | Denis Hunt | Devices and methods for purification |
SE0103084D0 (sv) | 2001-09-14 | 2001-09-14 | Amersham Pharm Biotech Ab | Generation of ion exchange media |
DE10155984A1 (de) | 2001-11-15 | 2003-05-28 | Boehringer Ingelheim Pharma | Verfahren zur Reduktion des Liganden-leakage von Affinitätschromatographie-Matrices |
EP2048154B2 (en) * | 2002-02-05 | 2015-06-03 | Genentech, Inc. | Protein purification |
CA2516518A1 (en) | 2003-02-28 | 2004-09-10 | Lonza Biologics Plc. | Antibody purification by protein a and ion exchange chromatography |
-
2004
- 2004-02-27 SE SE0400501A patent/SE0400501D0/xx unknown
-
2005
- 2005-02-24 WO PCT/SE2005/000292 patent/WO2005082926A1/en active Application Filing
- 2005-02-24 AT AT05722174T patent/ATE440858T1/de not_active IP Right Cessation
- 2005-02-24 KR KR1020067017115A patent/KR101149969B1/ko active IP Right Grant
- 2005-02-24 US US10/589,718 patent/US7385040B2/en active Active
- 2005-02-24 CN CN2005800062670A patent/CN1926146B/zh active Active
- 2005-02-24 NZ NZ548127A patent/NZ548127A/en not_active IP Right Cessation
- 2005-02-24 JP JP2007500724A patent/JP4776615B2/ja active Active
- 2005-02-24 EP EP05722174A patent/EP1718668B1/en active Active
- 2005-02-24 AU AU2005217348A patent/AU2005217348B2/en active Active
- 2005-02-24 CA CA2552823A patent/CA2552823C/en active Active
- 2005-02-24 DE DE602005016220T patent/DE602005016220D1/de active Active
- 2005-02-25 CN CN200580006276XA patent/CN1925898B/zh active Active
-
2006
- 2006-06-29 IL IL176635A patent/IL176635A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1925898A (zh) | 2007-03-07 |
AU2005217348B2 (en) | 2011-03-31 |
DE602005016220D1 (de) | 2009-10-08 |
CA2552823C (en) | 2013-11-19 |
CA2552823A1 (en) | 2005-09-09 |
US20070112178A1 (en) | 2007-05-17 |
NZ548127A (en) | 2009-09-25 |
CN1925898B (zh) | 2010-09-01 |
AU2005217348A1 (en) | 2005-09-09 |
CN1926146B (zh) | 2010-06-16 |
US7385040B2 (en) | 2008-06-10 |
EP1718668A1 (en) | 2006-11-08 |
KR20070001969A (ko) | 2007-01-04 |
KR101149969B1 (ko) | 2012-07-05 |
IL176635A0 (en) | 2006-10-31 |
ATE440858T1 (de) | 2009-09-15 |
IL176635A (en) | 2011-07-31 |
JP4776615B2 (ja) | 2011-09-21 |
CN1926146A (zh) | 2007-03-07 |
JP2008505851A (ja) | 2008-02-28 |
WO2005082926A1 (en) | 2005-09-09 |
EP1718668B1 (en) | 2009-08-26 |
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