DE602006020333D1 - Multimere fc-rezeptor-polypeptide - Google Patents

Multimere fc-rezeptor-polypeptide

Info

Publication number
DE602006020333D1
DE602006020333D1 DE602006020333T DE602006020333T DE602006020333D1 DE 602006020333 D1 DE602006020333 D1 DE 602006020333D1 DE 602006020333 T DE602006020333 T DE 602006020333T DE 602006020333 T DE602006020333 T DE 602006020333T DE 602006020333 D1 DE602006020333 D1 DE 602006020333D1
Authority
DE
Germany
Prior art keywords
protein
polypeptide
multimed
receptor polypeptides
riia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006020333T
Other languages
English (en)
Inventor
Phillip Mark Hogarth
Bruce David Wines
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suppremol GmbH
Original Assignee
Suppremol GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suppremol GmbH filed Critical Suppremol GmbH
Publication of DE602006020333D1 publication Critical patent/DE602006020333D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006020333T 2005-12-13 2006-12-13 Multimere fc-rezeptor-polypeptide Active DE602006020333D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75030105P 2005-12-13 2005-12-13
PCT/AU2006/001890 WO2007068047A1 (en) 2005-12-13 2006-12-13 Multimeric fc receptor polypeptides

Publications (1)

Publication Number Publication Date
DE602006020333D1 true DE602006020333D1 (de) 2011-04-07

Family

ID=38162476

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006020333T Active DE602006020333D1 (de) 2005-12-13 2006-12-13 Multimere fc-rezeptor-polypeptide

Country Status (7)

Country Link
EP (1) EP1960427B1 (de)
AT (1) ATE499384T1 (de)
DE (1) DE602006020333D1 (de)
ES (1) ES2359218T3 (de)
PL (1) PL1960427T3 (de)
PT (1) PT1960427E (de)
WO (1) WO2007068047A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2559887C (en) 2004-03-10 2018-12-04 Trinity Therapeutics, Inc. Method for inhibiting immune complex formation in a subject
BRPI0721078A2 (pt) * 2006-12-13 2014-10-07 Suppremol Gmbh POLIPEPTÍDEOS DE RECEPTORES Fc MULTIMÉRICOS INCLUINDO UM DOMÍNIO Fc MODIFICADO
US20120021988A1 (en) * 2007-08-14 2012-01-26 Bodie Neil M Methods for treating immune thrombocytopenia
AU2009270805B2 (en) 2008-07-18 2016-11-03 Trinity Therapeutics, Inc. Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome
US10669324B2 (en) 2012-10-30 2020-06-02 Suppremol Gmbh Vector encoding an Fc gamma receptor IIB protein and composition of the encoded protein
US10028998B2 (en) 2012-10-30 2018-07-24 Suppremol Gmbh Method for treating an inflammatory disease and/or an autoimmune disease with a soluble FcγRIIb
AU2012244302B2 (en) * 2012-10-31 2014-08-21 Suppremol Gmbh A method for treating or preventing either one or both of an inflammatory disease and an autoimmune disease
EP2796144A1 (de) 2013-04-26 2014-10-29 SuppreMol GmbH Hochkonzentrierte Formulierungen von löslichen Fc-Rezeptoren
EP2837637A1 (de) 2013-08-16 2015-02-18 SuppreMol GmbH Neuartiger FcyRIIB IgG-Antikörper

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006570A1 (en) * 1989-10-25 1991-05-16 The University Of Melbourne HYBRID Fc RECEPTOR MOLECULES
BRPI0406724A (pt) 2003-01-13 2005-12-20 Macrogenics Inc Proteìna de fusão dimérica, métodos de tratar, prevenir ou melhorar um ou mais sintomas de um distúrbio autoimune e um ou mais sintomas de púrpura trombocitopênica idiopática, composição farmacêutica, ácido nucleico, vetor, célula hospedeira, método de produzir recombinantemente o polipeptìdeo, polipeptìdeo isolado, fragmento de qualquer um dos polipeptìdeos, e, molécula de ácido nucleico isolada

Also Published As

Publication number Publication date
ES2359218T3 (es) 2011-05-19
PT1960427E (pt) 2011-03-22
EP1960427A1 (de) 2008-08-27
PL1960427T3 (pl) 2011-07-29
WO2007068047A1 (en) 2007-06-21
EP1960427A4 (de) 2009-03-04
EP1960427B1 (de) 2011-02-23
ATE499384T1 (de) 2011-03-15

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