DE69932944D1 - Kolonne und mit dieser durchgeführtes chromatographisches verfahren - Google Patents
Kolonne und mit dieser durchgeführtes chromatographisches verfahrenInfo
- Publication number
- DE69932944D1 DE69932944D1 DE69932944T DE69932944T DE69932944D1 DE 69932944 D1 DE69932944 D1 DE 69932944D1 DE 69932944 T DE69932944 T DE 69932944T DE 69932944 T DE69932944 T DE 69932944T DE 69932944 D1 DE69932944 D1 DE 69932944D1
- Authority
- DE
- Germany
- Prior art keywords
- ion exchange
- zwitterionic
- colonne
- carried out
- chromatographic method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/364—Amphoteric or zwitterionic ion-exchanger
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28078—Pore diameter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
- B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/3092—Packing of a container, e.g. packing a cartridge or column
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3278—Polymers being grafted on the carrier
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3285—Coating or impregnation layers comprising different type of functional groups or interactions, e.g. different ligands in various parts of the sorbent, mixed mode, dual zone, bimodal, multimodal, ionic or hydrophobic, cationic or anionic, hydrophilic or hydrophobic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
- B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J43/00—Amphoteric ion-exchange, i.e. using ion-exchangers having cationic and anionic groups; Use of material as amphoteric ion-exchangers; Treatment of material for improving their amphoteric ion-exchange properties
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/58—Use in a single column
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/80—Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J2220/82—Shaped bodies, e.g. monoliths, plugs, tubes, continuous beds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/524—Physical parameters structural properties
- G01N2030/528—Monolithic sorbent material
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9803838 | 1998-11-09 | ||
SE9803838A SE9803838D0 (sv) | 1998-11-09 | 1998-11-09 | A chromatography method and a column material useful in said method |
PCT/SE1999/002032 WO2000027496A1 (en) | 1998-11-09 | 1999-11-09 | A chromatography method and a column material useful in said method |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69932944D1 true DE69932944D1 (de) | 2006-10-05 |
DE69932944T2 DE69932944T2 (de) | 2007-05-10 |
Family
ID=20413235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69932944T Expired - Lifetime DE69932944T2 (de) | 1998-11-09 | 1999-11-09 | Chromatographisches verfahren und für das verfahren geeignetes säulenmaterial |
Country Status (9)
Country | Link |
---|---|
US (1) | US6884345B1 (de) |
EP (1) | EP1137466B1 (de) |
JP (1) | JP4440474B2 (de) |
AT (1) | ATE337058T1 (de) |
AU (1) | AU759683B2 (de) |
CA (1) | CA2349948C (de) |
DE (1) | DE69932944T2 (de) |
SE (1) | SE9803838D0 (de) |
WO (1) | WO2000027496A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10013990C2 (de) * | 2000-03-22 | 2003-12-04 | Invitek Biotechnik & Biodesign | Polyfunktionelles Trägermaterial für die komplexe Nukleinsäureanalytik |
US7238426B2 (en) * | 2003-08-13 | 2007-07-03 | Sequant Ab | Column packing material |
US7250388B2 (en) * | 2003-11-07 | 2007-07-31 | Hewlett-Packard Development Company, L.P. | Medium for chromatographic separations |
JP3922648B2 (ja) * | 2004-05-24 | 2007-05-30 | 株式会社資生堂 | アフィニティー粒子及びアフィニティー分離方法 |
CA2578202C (en) * | 2004-08-30 | 2013-12-17 | Toray Industries, Inc. | Fractionation apparatus |
US20100300971A1 (en) * | 2005-05-18 | 2010-12-02 | Sequant Ab | Zwitterionic stationary phase as well as method for using and producing said phase |
SE529259C2 (sv) * | 2005-08-31 | 2007-06-12 | Ge Healthcare Bio Sciences Ab | Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi |
SE0502485L (sv) * | 2005-11-09 | 2007-05-10 | Peter Viberg | Partiklar |
EP1962097A1 (de) * | 2007-02-23 | 2008-08-27 | SeQuant AB | Massenspektrometrischer quantitativer Nachweis von Methylmalonsäure und Bernsteinsäure unter Verwendung von HILIC auf einer zwitterionischen stationären Phase |
JP2009069050A (ja) | 2007-09-14 | 2009-04-02 | Nec Corp | 化合物のカラム担体への固定化方法 |
US9051349B2 (en) | 2007-11-21 | 2015-06-09 | Alba Therapeutics Corporation | Larazotide acetate compositions |
EP2062909A1 (de) * | 2007-11-21 | 2009-05-27 | SOLVAY (Société Anonyme) | Herstellung von Peptiden und Reinigungsverfahren |
US20110121229A1 (en) | 2008-05-13 | 2011-05-26 | Universitaet Wien | Enantioselective zwitterionic ion-exchange material |
US20090294362A1 (en) * | 2008-05-30 | 2009-12-03 | Persson Jonas Par | Stationary phase for hydrophilic interaction chromatography |
JP5767584B2 (ja) | 2008-09-02 | 2015-08-19 | ナトリックス セパレイションズ インコーポレーテッド | クロマトグラフィー膜、それを含む装置及びその使用方法 |
DE102009006007B4 (de) * | 2009-01-23 | 2015-03-12 | Axagarius Gmbh & Co. Kg | Verwendung von zwitterionischen Adsorbentien für die Flüssigchromatographie, Chromatographiesäule mit solchen Adsorbentien sowie deren Verwendung |
US10159911B2 (en) | 2009-08-04 | 2018-12-25 | Waters Technologies Corporation | High purity chromatographic materials comprising an ionizable modifier |
CN105126792A (zh) | 2009-08-04 | 2015-12-09 | 沃特世科技公司 | 包含可离子化改性剂的高纯度色谱材料 |
WO2011058439A1 (en) * | 2009-11-13 | 2011-05-19 | Natrix Separations, Inc. | Hydrophobic interaction chromatography membranes, and methods of use thereof |
BR112012016882B1 (pt) * | 2010-01-08 | 2021-02-23 | University Of Tasmania | método de armazenamento de um fluido corpóreo para análise futura |
JP2013534909A (ja) * | 2010-05-21 | 2013-09-09 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド | 両性イオン性試薬 |
JP5911046B2 (ja) * | 2010-07-01 | 2016-04-27 | 積水メディカル株式会社 | 核酸測定用液体クロマトグラフィー用カラム充填剤 |
KR20150023923A (ko) * | 2010-07-30 | 2015-03-05 | 이엠디 밀리포어 코포레이션 | 크로마토그래피 매질 및 방법 |
JP5929197B2 (ja) * | 2010-10-27 | 2016-06-01 | 東レ株式会社 | 血液成分吸着用担体及び血液成分吸着カラム |
JP5926484B2 (ja) | 2010-11-18 | 2016-05-25 | 株式会社セルシード | グリコサミノグリカンの新規な分析方法 |
WO2012082933A1 (en) | 2010-12-15 | 2012-06-21 | Baxter International, Inc. | Eluate collection using conductivity gradient |
CN102614847B (zh) | 2011-01-28 | 2013-12-18 | 浙江华谱新创科技有限公司 | 一种两性离子亲水色谱固定相及其制备方法 |
CN103392128B (zh) * | 2011-02-10 | 2016-05-04 | 积水医疗株式会社 | 离子交换色谱法用填充剂以及核酸链的分离检测方法 |
WO2012118097A1 (ja) | 2011-02-28 | 2012-09-07 | 株式会社セルシード | ヒアルロン酸産生能を有する細胞シート及びその製造方法 |
JP5807229B2 (ja) * | 2011-04-12 | 2015-11-10 | 学校法人中部大学 | マイコトキシンのスクリーニング法 |
EP3427815B1 (de) | 2011-05-17 | 2023-12-06 | Merck Millipore Ltd. | Vorrichtung mit geschichteten rohrmembranen für chromatographie |
BR112014000426B1 (pt) | 2011-07-12 | 2021-01-26 | University Of Tasmania | uso de um material de polímero poroso como um meio para a secagem e o armazenamento de uma amostra de fluido biológico; método de armazenamento de um fluido corporal para análise futura; método para o armazenamento e análise subsequente de uma amostra de fluido biológico |
CN103120932B (zh) * | 2013-03-01 | 2014-12-17 | 华东理工大学 | 一种阳离子多糖涂覆型亲水色谱固定相的制备方法及应用 |
WO2014194268A1 (en) * | 2013-05-30 | 2014-12-04 | The University Of Akron | Switchable antimicrobial and antifouling carboxybetaine-based hydrogels |
PL3019516T3 (pl) * | 2013-07-12 | 2019-04-30 | Hoffmann La Roche | Objaśnienie optymalizacji wprowadzania w chromatografii jonowymiennej |
US9340562B1 (en) * | 2014-10-29 | 2016-05-17 | Thermo Electron Manufacturing Limited | Chromatographic material and method for preparation thereof |
JP6729041B2 (ja) * | 2016-06-17 | 2020-07-22 | 日立化成株式会社 | 分離材及びカラム |
CA3067448A1 (en) * | 2017-06-22 | 2018-12-27 | Archer Daniels Midland Company | Process for separation and purification of a dicarboxylic acid containing mixture |
CN107597079B (zh) * | 2017-10-17 | 2020-06-16 | 暨南大学 | 一类基于两性离子交联剂的有机聚合物整体材料及制备和应用 |
CN109806916B (zh) * | 2019-03-15 | 2021-12-21 | 中科森辉微球技术(苏州)有限公司 | 高性能阴离子交换介质及其制备方法 |
CN114618454A (zh) * | 2020-12-11 | 2022-06-14 | 中国科学院大连化学物理研究所 | 一种极性包埋双链反相色谱固定相及其制备和应用 |
CN114190313B (zh) * | 2021-11-25 | 2023-04-11 | 舒城县汇德水产科技有限公司 | 一种环保型高密度红螯螯虾的繁殖育苗方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4577013A (en) * | 1983-12-22 | 1986-03-18 | Ciba-Geigy Corporation | Ionically modified cellulose material, its preparation and its use |
US6039876A (en) * | 1992-07-24 | 2000-03-21 | Yang; Yan-Bo | Hydrophilic polystrene divinylbenzene based matrixes for chromatography |
JP3351572B2 (ja) * | 1992-10-05 | 2002-11-25 | 井上 聰一 | イオンクロマトグラフィーによる分析体の分離・分析方法、イオンクロマトグラフィー用両荷電具備固定相及び多機能液体クロマトグラフィーによる分析体の分離・分析方法 |
WO1998049279A1 (en) * | 1997-04-25 | 1998-11-05 | Diamyd Therapeutics Ab | Use of a zwitterionic detergent/surfactant for purifying glutamic acid decarboxylase (gad) and a composition containing gad |
DE19721601A1 (de) * | 1997-05-23 | 1998-11-26 | Hoechst Ag | Polybetain-stabilisierte, Palladium-haltige Nanopartikel, ein Verfahren zu ihrer Herstellung sowie daraus hergestellte Katalysatoren zur Gewinnung von Vinylacetat |
DE19754304A1 (de) * | 1997-12-08 | 1999-06-10 | Hoechst Ag | Polybetain-stabilisierte Platin-Nanopartikel, Verfahren zu ihrer Herstellung und Verwendung für Elektrokatalysatoren in Brennstoffzellen |
US6238565B1 (en) * | 1998-09-16 | 2001-05-29 | Varian, Inc. | Monolithic matrix for separating bio-organic molecules |
-
1998
- 1998-11-09 SE SE9803838A patent/SE9803838D0/xx unknown
-
1999
- 1999-11-09 AT AT99958580T patent/ATE337058T1/de not_active IP Right Cessation
- 1999-11-09 US US09/831,162 patent/US6884345B1/en not_active Expired - Lifetime
- 1999-11-09 EP EP99958580A patent/EP1137466B1/de not_active Expired - Lifetime
- 1999-11-09 AU AU15919/00A patent/AU759683B2/en not_active Ceased
- 1999-11-09 WO PCT/SE1999/002032 patent/WO2000027496A1/en active IP Right Grant
- 1999-11-09 DE DE69932944T patent/DE69932944T2/de not_active Expired - Lifetime
- 1999-11-09 CA CA002349948A patent/CA2349948C/en not_active Expired - Fee Related
- 1999-11-09 JP JP2000580718A patent/JP4440474B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU1591900A (en) | 2000-05-29 |
WO2000027496A1 (en) | 2000-05-18 |
JP4440474B2 (ja) | 2010-03-24 |
DE69932944T2 (de) | 2007-05-10 |
CA2349948A1 (en) | 2000-05-18 |
JP2002529714A (ja) | 2002-09-10 |
CA2349948C (en) | 2008-10-14 |
AU759683B2 (en) | 2003-04-17 |
EP1137466B1 (de) | 2006-08-23 |
ATE337058T1 (de) | 2006-09-15 |
EP1137466A1 (de) | 2001-10-04 |
US6884345B1 (en) | 2005-04-26 |
SE9803838D0 (sv) | 1998-11-09 |
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