RU92016445A - Применение амидов изоксазол-4-карбоновой кислоты и амидов гидроксиалкилиденциануксусной кислоты - Google Patents
Применение амидов изоксазол-4-карбоновой кислоты и амидов гидроксиалкилиденциануксусной кислотыInfo
- Publication number
- RU92016445A RU92016445A RU92016445/14A RU92016445A RU92016445A RU 92016445 A RU92016445 A RU 92016445A RU 92016445/14 A RU92016445/14 A RU 92016445/14A RU 92016445 A RU92016445 A RU 92016445A RU 92016445 A RU92016445 A RU 92016445A
- Authority
- RU
- Russia
- Prior art keywords
- acid amides
- isoxoxol
- hydroxyalkylidenanicane
- application
- carboxylic acid
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title claims 2
- 150000001875 compounds Chemical class 0.000 claims 3
- LYPXTDXYEQEIIN-UHFFFAOYSA-N 1,2-oxazole-4-carboxylic acid Chemical class OC(=O)C=1C=NOC=1 LYPXTDXYEQEIIN-UHFFFAOYSA-N 0.000 claims 1
- 206010072736 Rheumatic disease Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
Claims (1)
- Производные амидов изоксазол-4-карбоновых кислот и производные амидов гидроксиалкилиден-циануксусных кислот пригодны для лечения раковых заболеваний. Эти соединения могут быть приготовлены известным методом. Часть этих соединений представляет собой новые соединения и пригодна для лечения ревматических заболеваний.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4016178 | 1990-05-18 | ||
DEP4016178.1 | 1990-05-18 | ||
DE4017020 | 1990-05-26 | ||
DEP4017043.8 | 1990-05-26 | ||
DE4017043 | 1990-05-26 | ||
DEP4017020.9 | 1990-05-26 | ||
PCT/EP1990/001800 WO1991017748A1 (de) | 1990-05-18 | 1990-10-24 | Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94033835A Division RU2142937C1 (ru) | 1990-05-18 | 1990-10-24 | Амиды органических кислот, способ их получения и фармацевтическая композиция |
Publications (2)
Publication Number | Publication Date |
---|---|
RU92016445A true RU92016445A (ru) | 1996-11-10 |
RU2084223C1 RU2084223C1 (ru) | 1997-07-20 |
Family
ID=27201216
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU9092016445A RU2084223C1 (ru) | 1990-05-18 | 1990-10-24 | Применение амидов изоказол-4-карбоновой кислоты и амидов гидроксиалкилиденциануксусной кислоты |
RU94033835A RU2142937C1 (ru) | 1990-05-18 | 1990-10-24 | Амиды органических кислот, способ их получения и фармацевтическая композиция |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94033835A RU2142937C1 (ru) | 1990-05-18 | 1990-10-24 | Амиды органических кислот, способ их получения и фармацевтическая композиция |
Country Status (28)
Country | Link |
---|---|
US (2) | US5494911A (ru) |
EP (1) | EP0527736B1 (ru) |
JP (3) | JP2995086B2 (ru) |
KR (1) | KR100188801B1 (ru) |
CN (1) | CN1051074C (ru) |
AT (1) | ATE151633T1 (ru) |
AU (2) | AU649421B2 (ru) |
BR (1) | BR9008022A (ru) |
CA (1) | CA2083179C (ru) |
CY (1) | CY2123B1 (ru) |
CZ (4) | CZ290474B6 (ru) |
DE (1) | DE59010701D1 (ru) |
DK (1) | DK0527736T3 (ru) |
ES (1) | ES2102367T3 (ru) |
FI (1) | FI105683B (ru) |
GR (1) | GR3023638T3 (ru) |
HU (1) | HU222234B1 (ru) |
IE (1) | IE911694A1 (ru) |
IL (1) | IL98163A (ru) |
LV (1) | LV10575B (ru) |
NO (1) | NO180118C (ru) |
NZ (1) | NZ238165A (ru) |
PT (1) | PT97689B (ru) |
RU (2) | RU2084223C1 (ru) |
SK (3) | SK281317B6 (ru) |
TW (2) | TW211558B (ru) |
WO (1) | WO1991017748A1 (ru) |
YU (1) | YU48765B (ru) |
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ATE174218T1 (de) * | 1993-01-08 | 1998-12-15 | Hoechst Ag | Verwendung von leflunomid zur hemmung von interleukin 1 beta |
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GB9313365D0 (en) * | 1993-06-29 | 1993-08-11 | Roussel Lab Ltd | Chemical compounds |
DE4323636A1 (de) * | 1993-07-15 | 1995-01-19 | Hoechst Ag | Arzneistoffzubereitungen aus umhüllten, schwerstwasserlöslichen Arzneistoffen für Inhalationsarzneiformen und Verfahren zu ihrer Herstellung |
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US6331555B1 (en) | 1995-06-01 | 2001-12-18 | University Of California | Treatment of platelet derived growth factor related disorders such as cancers |
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DE19539638A1 (de) * | 1995-10-25 | 1997-04-30 | Hoechst Ag | Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen |
DE19547648A1 (de) * | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
ATE316799T1 (de) * | 1996-03-12 | 2006-02-15 | Sanofi Aventis Deutschland | Neuartige prodrugs für die therapie von tumoren und entzündlichen erkrankungen |
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NL186239B (nl) * | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
DE2524959C2 (de) * | 1975-06-05 | 1983-02-10 | Hoechst Ag, 6000 Frankfurt | 5-Methyl-isoxazol-4-carbonsäureanilide, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Mittel |
ES448386A1 (es) * | 1975-06-05 | 1978-04-16 | Hoechst Ag | Procedimiento para la preparacion de anilidas de acido 5-me-til-isoxazol-4-carboxilico. |
DE2555789A1 (de) * | 1975-12-11 | 1977-07-07 | Hoechst Ag | Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
DE2557003A1 (de) * | 1975-12-18 | 1977-06-23 | Hoechst Ag | Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
DE2655009A1 (de) * | 1976-12-04 | 1978-06-15 | Hoechst Ag | Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
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DE3405727A1 (de) * | 1984-02-17 | 1985-08-22 | Hoechst Ag, 6230 Frankfurt | Isoxazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3534440A1 (de) * | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
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-
1990
- 1990-10-24 EP EP90915462A patent/EP0527736B1/de not_active Expired - Lifetime
- 1990-10-24 AT AT90915462T patent/ATE151633T1/de not_active IP Right Cessation
- 1990-10-24 ES ES90915462T patent/ES2102367T3/es not_active Expired - Lifetime
- 1990-10-24 CA CA002083179A patent/CA2083179C/en not_active Expired - Lifetime
- 1990-10-24 DK DK90915462.7T patent/DK0527736T3/da active
- 1990-10-24 WO PCT/EP1990/001800 patent/WO1991017748A1/de active IP Right Grant
- 1990-10-24 RU RU9092016445A patent/RU2084223C1/ru active
- 1990-10-24 BR BR909008022A patent/BR9008022A/pt not_active Application Discontinuation
- 1990-10-24 HU HU9203619A patent/HU222234B1/hu active IP Right Grant
- 1990-10-24 RU RU94033835A patent/RU2142937C1/ru active
- 1990-10-24 US US07/938,048 patent/US5494911A/en not_active Expired - Lifetime
- 1990-10-24 JP JP2514415A patent/JP2995086B2/ja not_active Expired - Lifetime
- 1990-10-24 KR KR1019920702895A patent/KR100188801B1/ko not_active IP Right Cessation
- 1990-10-24 DE DE59010701T patent/DE59010701D1/de not_active Expired - Lifetime
- 1990-10-24 AU AU65468/90A patent/AU649421B2/en not_active Expired
- 1990-10-27 TW TW081101406A patent/TW211558B/zh active
- 1990-10-27 TW TW079109110A patent/TW205004B/zh active
-
1991
- 1991-05-16 SK SK1376-98A patent/SK281317B6/sk not_active IP Right Cessation
- 1991-05-16 CN CN91103182A patent/CN1051074C/zh not_active Expired - Lifetime
- 1991-05-16 SK SK1450-91A patent/SK281316B6/sk not_active IP Right Cessation
- 1991-05-16 PT PT97689A patent/PT97689B/pt not_active IP Right Cessation
- 1991-05-16 NZ NZ238165A patent/NZ238165A/en not_active IP Right Cessation
- 1991-05-16 IL IL9816391A patent/IL98163A/en not_active IP Right Cessation
- 1991-05-16 SK SK542-99A patent/SK281318B6/sk not_active IP Right Cessation
- 1991-05-16 CZ CS19911450A patent/CZ290474B6/cs not_active IP Right Cessation
- 1991-05-17 IE IE169491A patent/IE911694A1/en not_active IP Right Cessation
- 1991-05-20 YU YU88491A patent/YU48765B/sr unknown
-
1992
- 1992-11-17 FI FI925211A patent/FI105683B/fi active
- 1992-11-17 NO NO924433A patent/NO180118C/no not_active IP Right Cessation
-
1993
- 1993-05-07 LV LVP-93-310A patent/LV10575B/en unknown
-
1994
- 1994-03-23 AU AU57992/94A patent/AU662465B2/en not_active Expired
-
1995
- 1995-06-07 US US08/476,278 patent/US5532259A/en not_active Expired - Lifetime
- 1995-08-24 CZ CZ19952176A patent/CZ290717B6/cs not_active IP Right Cessation
- 1995-11-23 CZ CZ19953092A patent/CZ290737B6/cs not_active IP Right Cessation
- 1995-11-23 CZ CZ19953091A patent/CZ290736B6/cs not_active IP Right Cessation
-
1997
- 1997-05-30 GR GR970401284T patent/GR3023638T3/el unknown
-
1998
- 1998-09-29 CY CY9800032A patent/CY2123B1/xx unknown
-
1999
- 1999-03-01 JP JP05210899A patent/JP3233610B2/ja not_active Expired - Lifetime
- 1999-03-01 JP JP05210799A patent/JP3201747B2/ja not_active Expired - Lifetime
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