RU2657773C2 - Композиция средства для чистки зубов в контейнере - Google Patents
Композиция средства для чистки зубов в контейнере Download PDFInfo
- Publication number
- RU2657773C2 RU2657773C2 RU2015120736A RU2015120736A RU2657773C2 RU 2657773 C2 RU2657773 C2 RU 2657773C2 RU 2015120736 A RU2015120736 A RU 2015120736A RU 2015120736 A RU2015120736 A RU 2015120736A RU 2657773 C2 RU2657773 C2 RU 2657773C2
- Authority
- RU
- Russia
- Prior art keywords
- container
- component
- weight
- composition
- dentifrice composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 160
- 239000000551 dentifrice Substances 0.000 title claims abstract description 115
- -1 polyethylene Polymers 0.000 claims abstract description 87
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims abstract description 34
- 239000004698 Polyethylene Substances 0.000 claims abstract description 27
- 229920000573 polyethylene Polymers 0.000 claims abstract description 27
- 239000004359 castor oil Substances 0.000 claims abstract description 23
- 235000019438 castor oil Nutrition 0.000 claims abstract description 23
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims abstract description 23
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims abstract description 22
- 239000004615 ingredient Substances 0.000 claims abstract description 22
- 229960003500 triclosan Drugs 0.000 claims abstract description 22
- IJALWSVNUBBQRA-UHFFFAOYSA-N 4-Isopropyl-3-methylphenol Chemical compound CC(C)C1=CC=C(O)C=C1C IJALWSVNUBBQRA-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 18
- 239000000194 fatty acid Substances 0.000 claims abstract description 18
- 229930195729 fatty acid Natural products 0.000 claims abstract description 18
- NFIDBGJMFKNGGQ-UHFFFAOYSA-N isopropylmethylphenol Natural products CC(C)CC1=CC=CC=C1O NFIDBGJMFKNGGQ-UHFFFAOYSA-N 0.000 claims abstract description 17
- 238000001179 sorption measurement Methods 0.000 claims abstract description 16
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 13
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 11
- 239000011732 tocopherol Substances 0.000 claims abstract description 9
- 229930003799 tocopherol Natural products 0.000 claims abstract description 9
- 229960001295 tocopherol Drugs 0.000 claims abstract description 9
- 235000010384 tocopherol Nutrition 0.000 claims abstract description 9
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims abstract description 9
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000011230 binding agent Substances 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 6
- 150000005846 sugar alcohols Chemical class 0.000 claims description 34
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 24
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 20
- 235000010356 sorbitol Nutrition 0.000 claims description 20
- 239000000600 sorbitol Substances 0.000 claims description 20
- 150000001875 compounds Chemical class 0.000 claims description 13
- 229940079593 drug Drugs 0.000 claims description 12
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 11
- 235000010418 carrageenan Nutrition 0.000 claims description 11
- 239000000679 carrageenan Substances 0.000 claims description 11
- 229920001525 carrageenan Polymers 0.000 claims description 11
- 229940113118 carrageenan Drugs 0.000 claims description 11
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 11
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 11
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 11
- 229920001285 xanthan gum Polymers 0.000 claims description 8
- 235000010493 xanthan gum Nutrition 0.000 claims description 8
- 239000000230 xanthan gum Substances 0.000 claims description 8
- 229940082509 xanthan gum Drugs 0.000 claims description 8
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 6
- 229920000591 gum Polymers 0.000 claims description 5
- 229940058015 1,3-butylene glycol Drugs 0.000 claims description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 3
- 229920002907 Guar gum Polymers 0.000 claims description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 229920001615 Tragacanth Polymers 0.000 claims description 3
- 239000000305 astragalus gummifer gum Substances 0.000 claims description 3
- 235000019437 butane-1,3-diol Nutrition 0.000 claims description 3
- 235000010417 guar gum Nutrition 0.000 claims description 3
- 239000000665 guar gum Substances 0.000 claims description 3
- 229960002154 guar gum Drugs 0.000 claims description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 3
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims description 3
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical group COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 claims description 3
- 229920001277 pectin Polymers 0.000 claims description 3
- 235000010987 pectin Nutrition 0.000 claims description 3
- 239000001814 pectin Substances 0.000 claims description 3
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 235000010413 sodium alginate Nutrition 0.000 claims description 3
- 239000000661 sodium alginate Substances 0.000 claims description 3
- 229940005550 sodium alginate Drugs 0.000 claims description 3
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 3
- 244000215068 Acacia senegal Species 0.000 claims description 2
- 229920002567 Chondroitin Polymers 0.000 claims description 2
- 229920002148 Gellan gum Polymers 0.000 claims description 2
- 229920000084 Gum arabic Polymers 0.000 claims description 2
- 229920000569 Gum karaya Polymers 0.000 claims description 2
- 229920000161 Locust bean gum Polymers 0.000 claims description 2
- 235000003805 Musa ABB Group Nutrition 0.000 claims description 2
- 240000008790 Musa x paradisiaca Species 0.000 claims description 2
- 235000015266 Plantago major Nutrition 0.000 claims description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 2
- 241000934878 Sterculia Species 0.000 claims description 2
- 240000004584 Tamarindus indica Species 0.000 claims description 2
- 235000004298 Tamarindus indica Nutrition 0.000 claims description 2
- 235000010489 acacia gum Nutrition 0.000 claims description 2
- 239000000205 acacia gum Substances 0.000 claims description 2
- DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 claims description 2
- 235000010494 karaya gum Nutrition 0.000 claims description 2
- 239000000231 karaya gum Substances 0.000 claims description 2
- 229940039371 karaya gum Drugs 0.000 claims description 2
- 235000010420 locust bean gum Nutrition 0.000 claims description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 2
- 235000011152 sodium sulphate Nutrition 0.000 claims description 2
- 235000010492 gellan gum Nutrition 0.000 claims 1
- 239000000216 gellan gum Substances 0.000 claims 1
- 238000005187 foaming Methods 0.000 abstract description 33
- 239000000126 substance Substances 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 4
- 229920001214 Polysorbate 60 Polymers 0.000 abstract description 3
- 230000002265 prevention Effects 0.000 abstract description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 24
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 21
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 19
- 229960002920 sorbitol Drugs 0.000 description 19
- 150000002148 esters Chemical class 0.000 description 12
- 150000003839 salts Chemical class 0.000 description 12
- 239000000377 silicon dioxide Substances 0.000 description 12
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 11
- 239000011626 DL-alpha-tocopherylacetate Substances 0.000 description 11
- 235000001809 DL-alpha-tocopherylacetate Nutrition 0.000 description 11
- 239000011734 sodium Substances 0.000 description 11
- 229910052708 sodium Inorganic materials 0.000 description 11
- 229940042585 tocopherol acetate Drugs 0.000 description 11
- 239000004386 Erythritol Substances 0.000 description 9
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 9
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 9
- 125000004432 carbon atom Chemical group C* 0.000 description 9
- 230000007423 decrease Effects 0.000 description 9
- 235000019414 erythritol Nutrition 0.000 description 9
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 9
- 229940009714 erythritol Drugs 0.000 description 9
- 239000002253 acid Substances 0.000 description 8
- 125000002252 acyl group Chemical group 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 8
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 8
- 229920001684 low density polyethylene Polymers 0.000 description 7
- 239000004702 low-density polyethylene Substances 0.000 description 7
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 7
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 239000006260 foam Substances 0.000 description 6
- 238000004128 high performance liquid chromatography Methods 0.000 description 6
- 235000012239 silicon dioxide Nutrition 0.000 description 6
- 230000008719 thickening Effects 0.000 description 6
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 5
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 5
- 230000014759 maintenance of location Effects 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 5
- 210000000214 mouth Anatomy 0.000 description 5
- 239000000811 xylitol Substances 0.000 description 5
- 235000010447 xylitol Nutrition 0.000 description 5
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 5
- 229960002675 xylitol Drugs 0.000 description 5
- PVXPPJIGRGXGCY-DJHAAKORSA-N 6-O-alpha-D-glucopyranosyl-alpha-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@](O)(CO)O1 PVXPPJIGRGXGCY-DJHAAKORSA-N 0.000 description 4
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 4
- 229930195725 Mannitol Natural products 0.000 description 4
- 125000004442 acylamino group Chemical group 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000000594 mannitol Substances 0.000 description 4
- 235000010355 mannitol Nutrition 0.000 description 4
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 4
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 4
- 235000010483 polyoxyethylene sorbitan monopalmitate Nutrition 0.000 description 4
- 239000000249 polyoxyethylene sorbitan monopalmitate Substances 0.000 description 4
- 239000008213 purified water Substances 0.000 description 4
- 159000000000 sodium salts Chemical class 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 3
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
- 235000021355 Stearic acid Nutrition 0.000 description 3
- 229930003427 Vitamin E Natural products 0.000 description 3
- 235000010724 Wisteria floribunda Nutrition 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- SUMDYPCJJOFFON-UHFFFAOYSA-N beta-hydroxyethanesulfonic acid Natural products OCCS(O)(=O)=O SUMDYPCJJOFFON-UHFFFAOYSA-N 0.000 description 3
- 230000001680 brushing effect Effects 0.000 description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 230000002349 favourable effect Effects 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 229920000092 linear low density polyethylene Polymers 0.000 description 3
- 239000004707 linear low-density polyethylene Substances 0.000 description 3
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 229920000053 polysorbate 80 Polymers 0.000 description 3
- 229940085605 saccharin sodium Drugs 0.000 description 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 3
- 229960004711 sodium monofluorophosphate Drugs 0.000 description 3
- 239000008117 stearic acid Substances 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 3
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 3
- 229940046009 vitamin E Drugs 0.000 description 3
- 235000019165 vitamin E Nutrition 0.000 description 3
- 239000011709 vitamin E Substances 0.000 description 3
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical class OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 229920001213 Polysorbate 20 Polymers 0.000 description 2
- 239000003082 abrasive agent Substances 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 230000035597 cooling sensation Effects 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 125000001165 hydrophobic group Chemical group 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 229940045996 isethionic acid Drugs 0.000 description 2
- 239000000832 lactitol Substances 0.000 description 2
- 235000010448 lactitol Nutrition 0.000 description 2
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 2
- 229960003451 lactitol Drugs 0.000 description 2
- 235000010449 maltitol Nutrition 0.000 description 2
- 239000000845 maltitol Substances 0.000 description 2
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 2
- 229940035436 maltitol Drugs 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 229920005862 polyol Polymers 0.000 description 2
- 150000003077 polyols Chemical class 0.000 description 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 229940071089 sarcosinate Drugs 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- ZUFONQSOSYEWCN-UHFFFAOYSA-M sodium;2-(methylamino)acetate Chemical compound [Na+].CNCC([O-])=O ZUFONQSOSYEWCN-UHFFFAOYSA-M 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- 239000000606 toothpaste Substances 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- AVFGLRAUULCLCH-UHFFFAOYSA-N 5-methyl-4-propan-2-ylcyclohexa-2,4-diene-1,1-diol Chemical compound OC1(CC(=C(C=C1)C(C)C)C)O AVFGLRAUULCLCH-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 244000090599 Plantago psyllium Species 0.000 description 1
- 235000010451 Plantago psyllium Nutrition 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- MSCCTZZBYHQMQJ-AZAGJHQNSA-N Tocopheryl nicotinate Chemical compound C([C@@](OC1=C(C)C=2C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)CC1=C(C)C=2OC(=O)C1=CC=CN=C1 MSCCTZZBYHQMQJ-AZAGJHQNSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 229940070800 myristoyl glutamate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 150000003016 phosphoric acids Chemical class 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229940077092 sodium myristoyl glutamate Drugs 0.000 description 1
- FCBUGCHAVCFTHW-NTISSMGPSA-N sodium;(2s)-2-(tetradecanoylamino)pentanedioic acid Chemical compound [Na].CCCCCCCCCCCCCC(=O)N[C@H](C(O)=O)CCC(O)=O FCBUGCHAVCFTHW-NTISSMGPSA-N 0.000 description 1
- CAVXVRQDZKMZDB-UHFFFAOYSA-M sodium;2-[dodecanoyl(methyl)amino]ethanesulfonate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CCS([O-])(=O)=O CAVXVRQDZKMZDB-UHFFFAOYSA-M 0.000 description 1
- ZNYIJXQYUNSKDX-NTISSMGPSA-M sodium;hydron;(2s)-2-(tetradecanoylamino)pentanedioate Chemical compound [Na+].CCCCCCCCCCCCCC(=O)N[C@H](C([O-])=O)CCC(O)=O ZNYIJXQYUNSKDX-NTISSMGPSA-M 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 229940104261 taurate Drugs 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229950009883 tocopheryl nicotinate Drugs 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/85—Polyesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012242734A JP6072512B2 (ja) | 2012-11-02 | 2012-11-02 | 容器入り歯磨組成物 |
| JP2012-242734 | 2012-11-02 | ||
| PCT/JP2013/079661 WO2014069614A1 (ja) | 2012-11-02 | 2013-11-01 | 容器入り歯磨組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015120736A RU2015120736A (ru) | 2016-12-27 |
| RU2657773C2 true RU2657773C2 (ru) | 2018-06-15 |
Family
ID=50627508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015120736A RU2657773C2 (ru) | 2012-11-02 | 2013-11-01 | Композиция средства для чистки зубов в контейнере |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP6072512B2 (zh) |
| CN (2) | CN104768526B (zh) |
| RU (1) | RU2657773C2 (zh) |
| TW (1) | TWI627970B (zh) |
| WO (1) | WO2014069614A1 (zh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6454093B2 (ja) * | 2014-06-10 | 2019-01-16 | 花王株式会社 | 容器入り歯磨組成物 |
| US9884719B2 (en) | 2014-12-12 | 2018-02-06 | Symbotic, LLC | Storage and retrieval system |
| US10214355B2 (en) | 2015-01-16 | 2019-02-26 | Symbotic, LLC | Storage and retrieval system |
| US11893533B2 (en) | 2015-01-16 | 2024-02-06 | Symbotic Llc | Storage and retrieval system |
| US10521767B2 (en) | 2015-01-16 | 2019-12-31 | Symbotic, LLC | Storage and retrieval system |
| US11254502B2 (en) | 2015-01-16 | 2022-02-22 | Symbotic Llc | Storage and retrieval system |
| US9856083B2 (en) | 2015-01-16 | 2018-01-02 | Symbotic, LLC | Storage and retrieval system |
| US9850079B2 (en) | 2015-01-23 | 2017-12-26 | Symbotic, LLC | Storage and retrieval system transport vehicle |
| JP7479254B2 (ja) * | 2015-04-07 | 2024-05-08 | ライオン株式会社 | 歯磨組成物及び歯磨組成物における容器へのイソプロピルメチルフェノールの吸着抑制方法 |
| JP6985786B2 (ja) * | 2015-04-07 | 2021-12-22 | ライオン株式会社 | 歯磨組成物及び歯磨組成物における容器へのイソプロピルメチルフェノールの吸着抑制方法 |
| JP6580871B2 (ja) * | 2015-06-02 | 2019-09-25 | 花王株式会社 | 練歯磨組成物 |
| EP3259197B1 (en) * | 2015-11-02 | 2021-11-24 | Kimpai Lamitube Co., Ltd. | Shoulder for a tube container made from melt-blended resin and tube container with this shoulder |
| WO2017209088A1 (ja) * | 2016-05-30 | 2017-12-07 | ライオン株式会社 | 口腔用組成物 |
| US11117743B2 (en) | 2017-09-28 | 2021-09-14 | Symbotic Llc | Storage and retrieval system |
| JP2022168043A (ja) * | 2020-09-14 | 2022-11-04 | ライオン株式会社 | 歯磨組成物及び歯磨組成物における容器へのイソプロピルメチルフェノールの吸着抑制方法 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04830A (ja) * | 1990-04-17 | 1992-01-06 | Toshiba Corp | ２ポートブリッジ装置 |
| RU2097019C1 (ru) * | 1990-07-02 | 1997-11-27 | Колгейт-Палмолив Компани | Упругий контейнер с заключенным в нем средством для чистки зубов |
| JP2002241279A (ja) * | 2001-02-16 | 2002-08-28 | Kanebo Ltd | 包装体入り製品及び吸着防止方法 |
| JP2005179266A (ja) * | 2003-12-19 | 2005-07-07 | Lion Corp | 歯磨剤組成物 |
| JP2005247786A (ja) * | 2004-03-05 | 2005-09-15 | Lion Corp | 歯磨剤組成物及び歯磨剤製品 |
| RU2389665C1 (ru) * | 2006-04-19 | 2010-05-20 | Колгейт-Палмолив Компани | Контейнер для продуктов, содержащих ароматические соединения |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04300830A (ja) * | 1991-03-28 | 1992-10-23 | Zeria Pharmaceut Co Ltd | ビタミンｅ類の水溶液の製剤 |
| JP3894132B2 (ja) * | 2003-02-20 | 2007-03-14 | ライオン株式会社 | 歯磨剤組成物 |
| CN102485781B (zh) * | 2010-12-06 | 2013-07-17 | 中国石油化工股份有限公司 | 大型容器内衬用聚乙烯组合物 |
-
2012
- 2012-11-02 JP JP2012242734A patent/JP6072512B2/ja active Active
-
2013
- 2013-11-01 CN CN201380057412.2A patent/CN104768526B/zh active Active
- 2013-11-01 RU RU2015120736A patent/RU2657773C2/ru active
- 2013-11-01 CN CN201810472090.2A patent/CN108451786A/zh active Pending
- 2013-11-01 WO PCT/JP2013/079661 patent/WO2014069614A1/ja active Application Filing
- 2013-11-01 TW TW102139849A patent/TWI627970B/zh active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04830A (ja) * | 1990-04-17 | 1992-01-06 | Toshiba Corp | ２ポートブリッジ装置 |
| RU2097019C1 (ru) * | 1990-07-02 | 1997-11-27 | Колгейт-Палмолив Компани | Упругий контейнер с заключенным в нем средством для чистки зубов |
| JP2002241279A (ja) * | 2001-02-16 | 2002-08-28 | Kanebo Ltd | 包装体入り製品及び吸着防止方法 |
| JP2005179266A (ja) * | 2003-12-19 | 2005-07-07 | Lion Corp | 歯磨剤組成物 |
| JP2005247786A (ja) * | 2004-03-05 | 2005-09-15 | Lion Corp | 歯磨剤組成物及び歯磨剤製品 |
| RU2389665C1 (ru) * | 2006-04-19 | 2010-05-20 | Колгейт-Палмолив Компани | Контейнер для продуктов, содержащих ароматические соединения |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014069614A1 (ja) | 2014-05-08 |
| TWI627970B (zh) | 2018-07-01 |
| CN104768526B (zh) | 2018-06-19 |
| TW201434485A (zh) | 2014-09-16 |
| JP6072512B2 (ja) | 2017-02-01 |
| CN104768526A (zh) | 2015-07-08 |
| RU2015120736A (ru) | 2016-12-27 |
| JP2014091698A (ja) | 2014-05-19 |
| CN108451786A (zh) | 2018-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2657773C2 (ru) | Композиция средства для чистки зубов в контейнере | |
| JP6052185B2 (ja) | 歯磨剤組成物 | |
| EP3238702B1 (en) | Liquid composition for oral cavity contained in foam-discharging container | |
| JP5105059B2 (ja) | 歯磨組成物 | |
| JP5007820B2 (ja) | 歯磨剤組成物 | |
| JP2011144160A (ja) | 口腔用組成物及び油性成分を多く含有する口腔用組成物の安定化方法 | |
| JP2016199473A (ja) | 歯磨組成物及び歯磨組成物における容器へのイソプロピルメチルフェノールの吸着抑制方法 | |
| JP2005247786A (ja) | 歯磨剤組成物及び歯磨剤製品 | |
| JP3978605B2 (ja) | 口腔用製品及び口腔用製品中におけるビタミンｅ又はその誘導体の安定配合方法 | |
| KR20130131395A (ko) | 치마제 조성물 | |
| JP2011136956A (ja) | 歯磨剤 | |
| JP2001031542A (ja) | 口腔用組成物 | |
| JP5275684B2 (ja) | 容器入り歯磨き組成物 | |
| JP4892951B2 (ja) | 練歯磨組成物 | |
| JP6459781B2 (ja) | 口腔用組成物 | |
| JP2011162524A (ja) | 非希釈液体口腔用組成物及びその使用方法 | |
| JP2005263753A (ja) | 液体口腔用組成物 | |
| JP4658744B2 (ja) | 歯磨き組成物 | |
| JP7076748B2 (ja) | 口腔用組成物 | |
| JP2007070258A (ja) | 歯磨き組成物 | |
| JP7479254B2 (ja) | 歯磨組成物及び歯磨組成物における容器へのイソプロピルメチルフェノールの吸着抑制方法 | |
| JP2006124292A (ja) | 歯磨組成物及びデキストラナーゼと塩化リゾチームとの同時安定化方法 | |
| JP2022168043A (ja) | 歯磨組成物及び歯磨組成物における容器へのイソプロピルメチルフェノールの吸着抑制方法 | |
| JP2014189523A (ja) | 歯磨剤組成物 |