RU2310445C2 - Применение гидроксиолеиновой кислоты и родственных соединений при производстве лекарственных средств - Google Patents
Применение гидроксиолеиновой кислоты и родственных соединений при производстве лекарственных средств Download PDFInfo
- Publication number
- RU2310445C2 RU2310445C2 RU2004114229/15A RU2004114229A RU2310445C2 RU 2310445 C2 RU2310445 C2 RU 2310445C2 RU 2004114229/15 A RU2004114229/15 A RU 2004114229/15A RU 2004114229 A RU2004114229 A RU 2004114229A RU 2310445 C2 RU2310445 C2 RU 2310445C2
- Authority
- RU
- Russia
- Prior art keywords
- acid
- proteins
- hydroxyoleic
- hydroxyoleic acid
- compounds
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ESP200102269 | 2001-10-11 | ||
| ES200102269A ES2186576B1 (es) | 2001-10-11 | 2001-10-11 | Acido 2-hidroxioleico para utilizar como medicamento. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2004114229A RU2004114229A (ru) | 2005-04-20 |
| RU2310445C2 true RU2310445C2 (ru) | 2007-11-20 |
Family
ID=8499164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004114229/15A RU2310445C2 (ru) | 2001-10-11 | 2002-10-09 | Применение гидроксиолеиновой кислоты и родственных соединений при производстве лекарственных средств |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20050014831A1 (enExample) |
| EP (1) | EP1435235B1 (enExample) |
| JP (1) | JP4737931B2 (enExample) |
| CN (3) | CN101259122B (enExample) |
| AT (1) | ATE322261T1 (enExample) |
| BR (1) | BRPI0213165B8 (enExample) |
| CA (1) | CA2463348C (enExample) |
| DE (1) | DE60210488T2 (enExample) |
| ES (2) | ES2186576B1 (enExample) |
| MX (1) | MXPA04003255A (enExample) |
| PT (1) | PT1435235E (enExample) |
| RU (1) | RU2310445C2 (enExample) |
| WO (1) | WO2003030891A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2513995C2 (ru) * | 2009-03-16 | 2014-04-27 | Липофарма Терапьютикс, С.Л. | Применение 2-гидроксипроизводных полиненасыщенных жирных кислот в качестве лекарственных препаратов |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2229935B1 (es) * | 2003-10-10 | 2006-10-01 | Universitat De Les Illes Balears | Utilizacion del acido hidroxioleico y compuestos analagos del mismo como aditivos alimentarios funcionales. |
| JP2009051732A (ja) * | 2005-12-13 | 2009-03-12 | Meiji Seika Kaisha Ltd | Pparリガンド活性を有する組成物 |
| CN101570481B (zh) * | 2008-04-30 | 2012-02-01 | 上海医药工业研究院 | 一种多羟基长链脂肪酸及其分离提取方法和在抑制芳香化酶活性中的应用 |
| ES2342997B1 (es) * | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| WO2011089265A1 (en) | 2010-01-25 | 2011-07-28 | Bridge Bioresearch Plc | Use of fatty acid compounds for lowering blood glucose levels |
| CN101985420B (zh) * | 2010-01-29 | 2014-04-30 | 苏州润新生物科技有限公司 | 油酸酯及其制备方法和在制备用于治疗高血压及其并发症的药物中的应用 |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| WO2013108428A1 (ja) * | 2012-01-19 | 2013-07-25 | 日本水産株式会社 | 食欲抑制剤 |
| WO2013132092A1 (en) | 2012-03-09 | 2013-09-12 | Pensieve International Plc | Use of monounsaturated fatty acid compounds for controlling the body weight of a dog or a cat |
| ES2734554T3 (es) * | 2012-09-26 | 2019-12-10 | Tangent Reprofiling Ltd | Combinación de benzo(iso)oxazolpiperidinas con ácido linoleico conjugado |
| GB201217296D0 (en) | 2012-09-27 | 2012-11-14 | Alta Innovations Ltd | Method of treatment and/or prevention |
| RU2679443C2 (ru) * | 2014-10-21 | 2019-02-11 | Университат Де Лес Ильес Балеарс | Способ синтеза гидрокситриглицеридов и их применение для профилактики и лечения заболеваний |
| US10756968B2 (en) | 2015-01-26 | 2020-08-25 | Rapid7, Inc. | Network resource management devices methods and systems |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987004926A2 (en) * | 1986-02-14 | 1987-08-27 | Nagy Adly Habib | Method of modifying the lipid structure of cell membranes and pharmaceutical compositions for use therein |
| WO1999058121A1 (en) * | 1998-05-08 | 1999-11-18 | Thia Medica As | Novel fatty analogues for the treatment of obesity, hypertension and fatty liver |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61297A (ja) * | 1984-06-12 | 1986-01-06 | 日本油脂株式会社 | オレイン酸の製造法 |
| JPS6344843A (ja) * | 1986-08-13 | 1988-02-25 | Kao Corp | 油中水中油型乳化油脂組成物 |
| CN1035925C (zh) * | 1988-11-16 | 1997-09-24 | 许正 | 亲细胞非均质分子脂质的制备方法 |
| US5422371A (en) * | 1992-05-27 | 1995-06-06 | Arch Development Corp. | Methods and compositions for inhibiting 5α-reductase activity |
| CN1118228A (zh) * | 1995-03-16 | 1996-03-13 | 姜训书 | 松籽果酱 |
| CN1118218A (zh) * | 1995-03-16 | 1996-03-13 | 姜训书 | 松籽油的制作方法及松籽保健食用油 |
| GB9506837D0 (en) * | 1995-04-03 | 1995-05-24 | Scotia Holdings Plc | Triglycerides |
| ES2192221T3 (es) * | 1995-10-30 | 2003-10-01 | Oleoyl Estrone Developments S | Monoesteres de oleato de estrogenos para el tratamiento de la obesidad o el sobrepeso. |
| US5856537A (en) * | 1996-06-26 | 1999-01-05 | The Scripps Research Institute | Inhibitors of oleamide hydrolase |
| DE19727636C1 (de) * | 1997-06-28 | 1998-11-19 | Rwe Dea Ag | Verfahren zur Herstellung von 2-Alkylcarbonsäuren |
| CN1212867A (zh) * | 1997-09-29 | 1999-04-07 | 宋凤亭 | 防治心脑血管疾病的组合物 |
| EP0948963B1 (en) * | 1998-01-21 | 2003-05-07 | Fideline | Pig appeasing pheromones to decrease stress, anxiety and aggressiveness |
| US6214875B1 (en) * | 1998-04-14 | 2001-04-10 | Zhenhua Yang | Anticancer effects of specific branched-chain fatty acids and related production process |
| GB2389788B (en) * | 2000-12-23 | 2005-07-20 | Univ Creighton | Methods for inducing apoptosis and inhibiting proliferation in cancer cells |
| DE10130491A1 (de) * | 2001-06-25 | 2003-04-17 | Heirler Horst | Verwendung von mittelkettigen Triglyceriden zur Prävention und Therapie von Adipositas |
-
2001
- 2001-10-11 ES ES200102269A patent/ES2186576B1/es not_active Expired - Fee Related
-
2002
- 2002-10-09 ES ES02783094T patent/ES2261752T3/es not_active Expired - Lifetime
- 2002-10-09 US US10/488,726 patent/US20050014831A1/en not_active Abandoned
- 2002-10-09 AT AT02783094T patent/ATE322261T1/de active
- 2002-10-09 DE DE60210488T patent/DE60210488T2/de not_active Expired - Lifetime
- 2002-10-09 JP JP2003533923A patent/JP4737931B2/ja not_active Expired - Lifetime
- 2002-10-09 EP EP02783094A patent/EP1435235B1/en not_active Expired - Lifetime
- 2002-10-09 CN CN2008100917941A patent/CN101259122B/zh not_active Expired - Fee Related
- 2002-10-09 RU RU2004114229/15A patent/RU2310445C2/ru active
- 2002-10-09 MX MXPA04003255A patent/MXPA04003255A/es active IP Right Grant
- 2002-10-09 BR BRPI0213165A patent/BRPI0213165B8/pt not_active IP Right Cessation
- 2002-10-09 PT PT02783094T patent/PT1435235E/pt unknown
- 2002-10-09 WO PCT/ES2002/000475 patent/WO2003030891A1/es not_active Ceased
- 2002-10-09 CA CA2463348A patent/CA2463348C/en not_active Expired - Lifetime
- 2002-10-09 CN CN2008100917937A patent/CN101259121B/zh not_active Expired - Fee Related
- 2002-10-09 CN CNB028201132A patent/CN100471492C/zh not_active Expired - Lifetime
-
2008
- 2008-04-15 US US12/082,938 patent/US7851507B2/en not_active Expired - Lifetime
-
2010
- 2010-11-04 US US12/939,641 patent/US8778995B2/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987004926A2 (en) * | 1986-02-14 | 1987-08-27 | Nagy Adly Habib | Method of modifying the lipid structure of cell membranes and pharmaceutical compositions for use therein |
| WO1999058121A1 (en) * | 1998-05-08 | 1999-11-18 | Thia Medica As | Novel fatty analogues for the treatment of obesity, hypertension and fatty liver |
Non-Patent Citations (2)
| Title |
|---|
| BANNI S. et al. Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. Nutr Cancer. 2001; 41(1-2):91-7. * |
| ДЖЕНКИНС Г., Хартунг У., «Химия органических лекарственных препаратов», М.: Государственное издательство иностранной литературы, 1949, стр.232-233. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2513995C2 (ru) * | 2009-03-16 | 2014-04-27 | Липофарма Терапьютикс, С.Л. | Применение 2-гидроксипроизводных полиненасыщенных жирных кислот в качестве лекарственных препаратов |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100471492C (zh) | 2009-03-25 |
| ES2261752T3 (es) | 2006-11-16 |
| CN101259122A (zh) | 2008-09-10 |
| US20090082446A1 (en) | 2009-03-26 |
| US20110136906A1 (en) | 2011-06-09 |
| CN1688302A (zh) | 2005-10-26 |
| BR0213165A (pt) | 2004-09-14 |
| CA2463348C (en) | 2011-04-05 |
| DE60210488T2 (de) | 2006-12-14 |
| DE60210488D1 (de) | 2006-05-18 |
| US8778995B2 (en) | 2014-07-15 |
| BRPI0213165B8 (pt) | 2021-05-25 |
| CA2463348A1 (en) | 2003-04-17 |
| ATE322261T1 (de) | 2006-04-15 |
| EP1435235A1 (en) | 2004-07-07 |
| US20050014831A1 (en) | 2005-01-20 |
| JP4737931B2 (ja) | 2011-08-03 |
| US7851507B2 (en) | 2010-12-14 |
| MXPA04003255A (es) | 2005-01-25 |
| RU2004114229A (ru) | 2005-04-20 |
| CN101259121A (zh) | 2008-09-10 |
| ES2186576A1 (es) | 2003-05-01 |
| JP2005527479A (ja) | 2005-09-15 |
| EP1435235B1 (en) | 2006-04-05 |
| CN101259121B (zh) | 2011-04-06 |
| WO2003030891A1 (es) | 2003-04-17 |
| BRPI0213165B1 (pt) | 2018-01-23 |
| PT1435235E (pt) | 2006-08-31 |
| CN101259122B (zh) | 2011-04-06 |
| ES2186576B1 (es) | 2004-09-16 |
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