BRPI0213165B8 - uso de ácido hidroxioléico e compostos relacionados na manufatura de drogas - Google Patents
uso de ácido hidroxioléico e compostos relacionados na manufatura de drogasInfo
- Publication number
- BRPI0213165B8 BRPI0213165B8 BRPI0213165A BR0213165A BRPI0213165B8 BR PI0213165 B8 BRPI0213165 B8 BR PI0213165B8 BR PI0213165 A BRPI0213165 A BR PI0213165A BR 0213165 A BR0213165 A BR 0213165A BR PI0213165 B8 BRPI0213165 B8 BR PI0213165B8
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxyoleic acid
- related compounds
- drug manufacturing
- drugs
- manufacture
- Prior art date
Links
- JBSOOFITVPOOSY-KTKRTIGZSA-N 2-hydroxyoleic acid Chemical compound CCCCCCCC\C=C/CCCCCCC(O)C(O)=O JBSOOFITVPOOSY-KTKRTIGZSA-N 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000007905 drug manufacturing Methods 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 108091006027 G proteins Proteins 0.000 abstract 1
- 102000030782 GTP binding Human genes 0.000 abstract 1
- 108091000058 GTP-Binding Proteins 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200102269A ES2186576B1 (es) | 2001-10-11 | 2001-10-11 | Acido 2-hidroxioleico para utilizar como medicamento. |
| ESP200102269 | 2001-10-11 | ||
| PCT/ES2002/000475 WO2003030891A1 (es) | 2001-10-11 | 2002-10-09 | Utilizacion del acido hidroxioleico y compuestos analogos del mismo en la fabricacion de medicamentos |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0213165A BR0213165A (pt) | 2004-09-14 |
| BRPI0213165B1 BRPI0213165B1 (pt) | 2018-01-23 |
| BRPI0213165B8 true BRPI0213165B8 (pt) | 2021-05-25 |
Family
ID=8499164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0213165A BRPI0213165B8 (pt) | 2001-10-11 | 2002-10-09 | uso de ácido hidroxioléico e compostos relacionados na manufatura de drogas |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20050014831A1 (enExample) |
| EP (1) | EP1435235B1 (enExample) |
| JP (1) | JP4737931B2 (enExample) |
| CN (3) | CN101259122B (enExample) |
| AT (1) | ATE322261T1 (enExample) |
| BR (1) | BRPI0213165B8 (enExample) |
| CA (1) | CA2463348C (enExample) |
| DE (1) | DE60210488T2 (enExample) |
| ES (2) | ES2186576B1 (enExample) |
| MX (1) | MXPA04003255A (enExample) |
| PT (1) | PT1435235E (enExample) |
| RU (1) | RU2310445C2 (enExample) |
| WO (1) | WO2003030891A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2229935B1 (es) * | 2003-10-10 | 2006-10-01 | Universitat De Les Illes Balears | Utilizacion del acido hidroxioleico y compuestos analagos del mismo como aditivos alimentarios funcionales. |
| JP2009051732A (ja) * | 2005-12-13 | 2009-03-12 | Meiji Seika Kaisha Ltd | Ｐｐａｒリガンド活性を有する組成物 |
| CN101570481B (zh) * | 2008-04-30 | 2012-02-01 | 上海医药工业研究院 | 一种多羟基长链脂肪酸及其分离提取方法和在抑制芳香化酶活性中的应用 |
| ES2342997B1 (es) * | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| ES2345241B1 (es) * | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| WO2011089265A1 (en) | 2010-01-25 | 2011-07-28 | Bridge Bioresearch Plc | Use of fatty acid compounds for lowering blood glucose levels |
| CN101985420B (zh) * | 2010-01-29 | 2014-04-30 | 苏州润新生物科技有限公司 | 油酸酯及其制备方法和在制备用于治疗高血压及其并发症的药物中的应用 |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| JP6053695B2 (ja) * | 2012-01-19 | 2016-12-27 | 日本水産株式会社 | 食欲抑制剤 |
| WO2013132092A1 (en) | 2012-03-09 | 2013-09-12 | Pensieve International Plc | Use of monounsaturated fatty acid compounds for controlling the body weight of a dog or a cat |
| ES2734554T3 (es) * | 2012-09-26 | 2019-12-10 | Tangent Reprofiling Ltd | Combinación de benzo(iso)oxazolpiperidinas con ácido linoleico conjugado |
| GB201217296D0 (en) | 2012-09-27 | 2012-11-14 | Alta Innovations Ltd | Method of treatment and/or prevention |
| RU2679443C2 (ru) * | 2014-10-21 | 2019-02-11 | Университат Де Лес Ильес Балеарс | Способ синтеза гидрокситриглицеридов и их применение для профилактики и лечения заболеваний |
| US10756968B2 (en) | 2015-01-26 | 2020-08-25 | Rapid7, Inc. | Network resource management devices methods and systems |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61297A (ja) * | 1984-06-12 | 1986-01-06 | 日本油脂株式会社 | オレイン酸の製造法 |
| GB8603621D0 (en) * | 1986-02-14 | 1986-03-19 | Habib N | Modifying lipid structure of cell membranes |
| JPS6344843A (ja) * | 1986-08-13 | 1988-02-25 | Kao Corp | 油中水中油型乳化油脂組成物 |
| CN1035925C (zh) * | 1988-11-16 | 1997-09-24 | 许正 | 亲细胞非均质分子脂质的制备方法 |
| US5422371A (en) * | 1992-05-27 | 1995-06-06 | Arch Development Corp. | Methods and compositions for inhibiting 5α-reductase activity |
| CN1118228A (zh) * | 1995-03-16 | 1996-03-13 | 姜训书 | 松籽果酱 |
| CN1118218A (zh) * | 1995-03-16 | 1996-03-13 | 姜训书 | 松籽油的制作方法及松籽保健食用油 |
| GB9506837D0 (en) * | 1995-04-03 | 1995-05-24 | Scotia Holdings Plc | Triglycerides |
| DK0771817T3 (da) * | 1995-10-30 | 2003-07-28 | Oleoyl Estrone Developments S | Oleatmonoestere af østrogener til behandling af obesitet og/eller overvægt |
| US5856537A (en) * | 1996-06-26 | 1999-01-05 | The Scripps Research Institute | Inhibitors of oleamide hydrolase |
| DE19727636C1 (de) * | 1997-06-28 | 1998-11-19 | Rwe Dea Ag | Verfahren zur Herstellung von 2-Alkylcarbonsäuren |
| CN1212867A (zh) * | 1997-09-29 | 1999-04-07 | 宋凤亭 | 防治心脑血管疾病的组合物 |
| US6077867A (en) * | 1998-01-21 | 2000-06-20 | Fideline | Pig appeasing pheromones to decrease stress, anxiety and aggressiveness |
| US6214875B1 (en) * | 1998-04-14 | 2001-04-10 | Zhenhua Yang | Anticancer effects of specific branched-chain fatty acids and related production process |
| WO1999058120A1 (en) * | 1998-05-08 | 1999-11-18 | Rolf Berge | USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS |
| GB2389788B (en) * | 2000-12-23 | 2005-07-20 | Univ Creighton | Methods for inducing apoptosis and inhibiting proliferation in cancer cells |
| DE10130491A1 (de) * | 2001-06-25 | 2003-04-17 | Heirler Horst | Verwendung von mittelkettigen Triglyceriden zur Prävention und Therapie von Adipositas |
-
2001
- 2001-10-11 ES ES200102269A patent/ES2186576B1/es not_active Expired - Fee Related
-
2002
- 2002-10-09 CN CN2008100917941A patent/CN101259122B/zh not_active Expired - Fee Related
- 2002-10-09 EP EP02783094A patent/EP1435235B1/en not_active Expired - Lifetime
- 2002-10-09 CN CNB028201132A patent/CN100471492C/zh not_active Expired - Lifetime
- 2002-10-09 WO PCT/ES2002/000475 patent/WO2003030891A1/es not_active Ceased
- 2002-10-09 MX MXPA04003255A patent/MXPA04003255A/es active IP Right Grant
- 2002-10-09 JP JP2003533923A patent/JP4737931B2/ja not_active Expired - Lifetime
- 2002-10-09 AT AT02783094T patent/ATE322261T1/de active
- 2002-10-09 US US10/488,726 patent/US20050014831A1/en not_active Abandoned
- 2002-10-09 PT PT02783094T patent/PT1435235E/pt unknown
- 2002-10-09 BR BRPI0213165A patent/BRPI0213165B8/pt not_active IP Right Cessation
- 2002-10-09 ES ES02783094T patent/ES2261752T3/es not_active Expired - Lifetime
- 2002-10-09 RU RU2004114229/15A patent/RU2310445C2/ru active
- 2002-10-09 CA CA2463348A patent/CA2463348C/en not_active Expired - Lifetime
- 2002-10-09 DE DE60210488T patent/DE60210488T2/de not_active Expired - Lifetime
- 2002-10-09 CN CN2008100917937A patent/CN101259121B/zh not_active Expired - Fee Related
-
2008
- 2008-04-15 US US12/082,938 patent/US7851507B2/en not_active Expired - Lifetime
-
2010
- 2010-11-04 US US12/939,641 patent/US8778995B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1435235E (pt) | 2006-08-31 |
| US20110136906A1 (en) | 2011-06-09 |
| CN101259122B (zh) | 2011-04-06 |
| WO2003030891A1 (es) | 2003-04-17 |
| ES2261752T3 (es) | 2006-11-16 |
| ES2186576A1 (es) | 2003-05-01 |
| EP1435235B1 (en) | 2006-04-05 |
| US7851507B2 (en) | 2010-12-14 |
| US20090082446A1 (en) | 2009-03-26 |
| CN1688302A (zh) | 2005-10-26 |
| ES2186576B1 (es) | 2004-09-16 |
| JP4737931B2 (ja) | 2011-08-03 |
| CN101259122A (zh) | 2008-09-10 |
| BRPI0213165B1 (pt) | 2018-01-23 |
| JP2005527479A (ja) | 2005-09-15 |
| CN101259121A (zh) | 2008-09-10 |
| CN100471492C (zh) | 2009-03-25 |
| CA2463348C (en) | 2011-04-05 |
| BR0213165A (pt) | 2004-09-14 |
| EP1435235A1 (en) | 2004-07-07 |
| MXPA04003255A (es) | 2005-01-25 |
| CN101259121B (zh) | 2011-04-06 |
| DE60210488D1 (de) | 2006-05-18 |
| ATE322261T1 (de) | 2006-04-15 |
| US20050014831A1 (en) | 2005-01-20 |
| RU2004114229A (ru) | 2005-04-20 |
| CA2463348A1 (en) | 2003-04-17 |
| DE60210488T2 (de) | 2006-12-14 |
| US8778995B2 (en) | 2014-07-15 |
| RU2310445C2 (ru) | 2007-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/10/2002 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
| B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 09/10/2022 |