RU2190594C2 - Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе - Google Patents

Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе Download PDF

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RU2190594C2
RU2190594C2 RU99112517/04A RU99112517A RU2190594C2 RU 2190594 C2 RU2190594 C2 RU 2190594C2 RU 99112517/04 A RU99112517/04 A RU 99112517/04A RU 99112517 A RU99112517 A RU 99112517A RU 2190594 C2 RU2190594 C2 RU 2190594C2
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iia
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carbon atoms
groups
activity
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RU99112517/04A
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English (en)
Russian (ru)
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RU99112517A (ru
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Солдато Пьеро Дель
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Никокс С.А.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Peptides Or Proteins (AREA)
RU99112517/04A 1996-11-14 1997-11-12 Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе RU2190594C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI002368A IT1295694B1 (it) 1996-11-14 1996-11-14 Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
ITMI96A002368 1996-11-14

Publications (2)

Publication Number Publication Date
RU99112517A RU99112517A (ru) 2001-04-10
RU2190594C2 true RU2190594C2 (ru) 2002-10-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU99112517/04A RU2190594C2 (ru) 1996-11-14 1997-11-12 Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе

Country Status (18)

Country Link
US (1) US6242432B1 (enExample)
EP (1) EP0941218B1 (enExample)
JP (1) JP4264137B2 (enExample)
KR (1) KR100504122B1 (enExample)
CN (1) CN1094931C (enExample)
AT (1) ATE226199T1 (enExample)
AU (1) AU729423B2 (enExample)
BR (1) BR9712959B1 (enExample)
CA (1) CA2272063C (enExample)
DE (1) DE69716461T2 (enExample)
DK (1) DK0941218T3 (enExample)
ES (1) ES2186013T3 (enExample)
HU (1) HUP0000667A3 (enExample)
IL (1) IL129768A (enExample)
IT (1) IT1295694B1 (enExample)
PT (1) PT941218E (enExample)
RU (1) RU2190594C2 (enExample)
WO (1) WO1998021193A1 (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2322972C1 (ru) * 2006-09-12 2008-04-27 Илья Николаевич Медведев Способ профилактики тромбозов у больных артериальной гипертонией с метаболическим синдромом

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WO2002034303A1 (en) * 2000-10-27 2002-05-02 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
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EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
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Publication number Priority date Publication date Assignee Title
RU2322972C1 (ru) * 2006-09-12 2008-04-27 Илья Николаевич Медведев Способ профилактики тромбозов у больных артериальной гипертонией с метаболическим синдромом

Also Published As

Publication number Publication date
BR9712959A (pt) 2000-02-01
EP0941218A1 (en) 1999-09-15
ITMI962368A1 (it) 1998-05-14
ITMI962368A0 (it) 1996-11-14
BR9712959B1 (pt) 2010-06-01
KR100504122B1 (ko) 2005-07-27
IT1295694B1 (it) 1999-05-27
CA2272063A1 (en) 1998-05-22
JP4264137B2 (ja) 2009-05-13
ES2186013T3 (es) 2003-05-01
AU729423B2 (en) 2001-02-01
PT941218E (pt) 2003-03-31
DE69716461D1 (de) 2002-11-21
IL129768A (en) 2004-02-19
JP2001507676A (ja) 2001-06-12
CA2272063C (en) 2008-05-27
KR20000053251A (ko) 2000-08-25
US6242432B1 (en) 2001-06-05
AU5551998A (en) 1998-06-03
CN1094931C (zh) 2002-11-27
DK0941218T3 (da) 2003-02-17
ATE226199T1 (de) 2002-11-15
HUP0000667A3 (en) 2000-08-28
EP0941218B1 (en) 2002-10-16
DE69716461T2 (de) 2003-06-26
IL129768A0 (en) 2000-02-29
CN1242768A (zh) 2000-01-26
HUP0000667A2 (en) 2000-07-28
WO1998021193A1 (en) 1998-05-22

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