DK0941218T3 - Antithrombotiske organiske nitrater - Google Patents

Antithrombotiske organiske nitrater

Info

Publication number
DK0941218T3
DK0941218T3 DK97951890T DK97951890T DK0941218T3 DK 0941218 T3 DK0941218 T3 DK 0941218T3 DK 97951890 T DK97951890 T DK 97951890T DK 97951890 T DK97951890 T DK 97951890T DK 0941218 T3 DK0941218 T3 DK 0941218T3
Authority
DK
Denmark
Prior art keywords
antithrombotic
organic nitrates
compounds
analapril
timolol
Prior art date
Application number
DK97951890T
Other languages
English (en)
Inventor
Soldato Piero Del
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Application granted granted Critical
Publication of DK0941218T3 publication Critical patent/DK0941218T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Peptides Or Proteins (AREA)
DK97951890T 1996-11-14 1997-11-12 Antithrombotiske organiske nitrater DK0941218T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI002368A IT1295694B1 (it) 1996-11-14 1996-11-14 Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
PCT/EP1997/006311 WO1998021193A1 (en) 1996-11-14 1997-11-12 Antithrombotic organic nitrates

Publications (1)

Publication Number Publication Date
DK0941218T3 true DK0941218T3 (da) 2003-02-17

Family

ID=11375213

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97951890T DK0941218T3 (da) 1996-11-14 1997-11-12 Antithrombotiske organiske nitrater

Country Status (18)

Country Link
US (1) US6242432B1 (da)
EP (1) EP0941218B1 (da)
JP (1) JP4264137B2 (da)
KR (1) KR100504122B1 (da)
CN (1) CN1094931C (da)
AT (1) ATE226199T1 (da)
AU (1) AU729423B2 (da)
BR (1) BR9712959B1 (da)
CA (1) CA2272063C (da)
DE (1) DE69716461T2 (da)
DK (1) DK0941218T3 (da)
ES (1) ES2186013T3 (da)
HU (1) HUP0000667A3 (da)
IL (1) IL129768A (da)
IT (1) IT1295694B1 (da)
PT (1) PT941218E (da)
RU (1) RU2190594C2 (da)
WO (1) WO1998021193A1 (da)

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US7708989B2 (en) 1999-10-29 2010-05-04 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
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US20070207217A1 (en) * 2003-02-03 2007-09-06 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO
US7166638B2 (en) 2003-05-27 2007-01-23 Nicox S.A. Statin derivatives
US7169805B2 (en) 2003-05-28 2007-01-30 Nicox S.A. Captopril derivatives
PL379197A1 (pl) * 2003-06-19 2006-07-24 Nicox S.A. Nitroksylowe pochodne enalaprilu i pokrewne związki jako inhibitory ACE do leczenia chorób sercowo-naczyniowych
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IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
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Also Published As

Publication number Publication date
ES2186013T3 (es) 2003-05-01
IL129768A0 (en) 2000-02-29
RU2190594C2 (ru) 2002-10-10
DE69716461T2 (de) 2003-06-26
EP0941218B1 (en) 2002-10-16
BR9712959A (pt) 2000-02-01
HUP0000667A2 (en) 2000-07-28
DE69716461D1 (de) 2002-11-21
JP2001507676A (ja) 2001-06-12
US6242432B1 (en) 2001-06-05
AU5551998A (en) 1998-06-03
WO1998021193A1 (en) 1998-05-22
AU729423B2 (en) 2001-02-01
BR9712959B1 (pt) 2010-06-01
KR20000053251A (ko) 2000-08-25
KR100504122B1 (ko) 2005-07-27
CN1094931C (zh) 2002-11-27
ATE226199T1 (de) 2002-11-15
IL129768A (en) 2004-02-19
ITMI962368A0 (it) 1996-11-14
PT941218E (pt) 2003-03-31
CA2272063A1 (en) 1998-05-22
CA2272063C (en) 2008-05-27
CN1242768A (zh) 2000-01-26
ITMI962368A1 (it) 1998-05-14
HUP0000667A3 (en) 2000-08-28
JP4264137B2 (ja) 2009-05-13
IT1295694B1 (it) 1999-05-27
EP0941218A1 (en) 1999-09-15

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