RU2165921C2 - Нитросоединения и фармацевтическая композиция, обладающие противовоспалительной и антитромботической активностями - Google Patents

Нитросоединения и фармацевтическая композиция, обладающие противовоспалительной и антитромботической активностями Download PDF

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RU2165921C2
RU2165921C2 RU98110565/04A RU98110565A RU2165921C2 RU 2165921 C2 RU2165921 C2 RU 2165921C2 RU 98110565/04 A RU98110565/04 A RU 98110565/04A RU 98110565 A RU98110565 A RU 98110565A RU 2165921 C2 RU2165921 C2 RU 2165921C2
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Russia
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ono
inflammatory
products
cox
group
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RU98110565/04A
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English (en)
Russian (ru)
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RU98110565A (ru
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Солдато Пьеро Дел
Франческо Санниколо
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Никокс С.А.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU98110565/04A 1995-10-31 1996-10-29 Нитросоединения и фармацевтическая композиция, обладающие противовоспалительной и антитромботической активностями RU2165921C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI002263A IT1276071B1 (it) 1995-10-31 1995-10-31 Compositi ad attivita' anti-infiammatoria
ITM195A002263 1995-10-31

Publications (2)

Publication Number Publication Date
RU98110565A RU98110565A (ru) 2000-04-27
RU2165921C2 true RU2165921C2 (ru) 2001-04-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU98110565/04A RU2165921C2 (ru) 1995-10-31 1996-10-29 Нитросоединения и фармацевтическая композиция, обладающие противовоспалительной и антитромботической активностями

Country Status (18)

Country Link
US (1) US6040341A (https=)
EP (1) EP0871606B1 (https=)
JP (1) JP3880067B2 (https=)
KR (1) KR100546038B1 (https=)
AT (1) ATE193883T1 (https=)
AU (1) AU709338B2 (https=)
BR (1) BR9611175B1 (https=)
CA (1) CA2235996C (https=)
DE (1) DE69608916T2 (https=)
DK (1) DK0871606T3 (https=)
ES (1) ES2148808T3 (https=)
GR (1) GR3033827T3 (https=)
HU (1) HUP9802986A3 (https=)
IT (1) IT1276071B1 (https=)
PT (1) PT871606E (https=)
RU (1) RU2165921C2 (https=)
SI (1) SI0871606T1 (https=)
WO (1) WO1997016405A1 (https=)

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RU2322434C2 (ru) * 2002-09-20 2008-04-20 Никокс С.А. Способ получения no-донорных соединений, таких как no-донорный диклофенак

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US7115661B1 (en) 1999-12-29 2006-10-03 Queen's University At Kingston Methods and compositions for mitigating pain
US20050137191A1 (en) * 1996-06-04 2005-06-23 Thatcher Gregory R. Nitrate esters and their use for mitigating cellular damage
US20040082652A1 (en) * 1996-09-04 2004-04-29 Nicox S.A. Nitric ester derivatives and their use in treating gastrointestinal tumors
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US6136804A (en) 1998-03-13 2000-10-24 Merck & Co., Inc. Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
ES2136581B1 (es) 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
EP1085845A2 (en) 1998-06-08 2001-03-28 Advanced Medicine, Inc. Multibinding inhibitors of cyclooxygenase-2
WO2000018352A2 (en) * 1998-09-28 2000-04-06 Merck & Co., Inc. A method for treating inflammatory diseases by administering a thrombin inhibitor
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IT1307928B1 (it) * 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.
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US6509377B1 (en) * 1999-05-26 2003-01-21 J. Uriach & Cia, S.A. Use of a 2-hydroxy-4-trifluoromethylbenzoic acid derivatives as inhibitors of the activation of the nuclear transcription factor NF-κB
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ITMI991517A1 (it) * 1999-07-09 2001-01-09 Nicox Sa Procedimento per ottenere nitrossimetil fenil esterni di derivati dell'acido salicilico
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ITMI20011240A1 (it) * 2001-06-13 2002-12-13 Nicox Sa Farmaci per le vasculopatie
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US7011854B2 (en) 2002-02-04 2006-03-14 Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
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US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
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WO1992001668A1 (en) * 1990-07-26 1992-02-06 Italfarmaco S.P.A. Benzoic acid substituted derivatives having cardiovascular activity
WO1994012463A1 (en) * 1992-11-26 1994-06-09 Nicox Limited Nitric esters having a pharmacological activity and process for their preparation
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2322434C2 (ru) * 2002-09-20 2008-04-20 Никокс С.А. Способ получения no-донорных соединений, таких как no-донорный диклофенак

Also Published As

Publication number Publication date
PT871606E (pt) 2000-11-30
DE69608916D1 (de) 2000-07-20
JP3880067B2 (ja) 2007-02-14
AU7495096A (en) 1997-05-22
GR3033827T3 (en) 2000-10-31
DK0871606T3 (da) 2000-07-31
CA2235996A1 (en) 1997-05-09
US6040341A (en) 2000-03-21
CA2235996C (en) 2007-01-02
BR9611175A (pt) 1999-03-30
HUP9802986A2 (hu) 1999-04-28
BR9611175B1 (pt) 2009-01-13
SI0871606T1 (en) 2000-08-31
IT1276071B1 (it) 1997-10-24
EP0871606A1 (en) 1998-10-21
WO1997016405A1 (en) 1997-05-09
ITMI952263A1 (it) 1997-05-01
AU709338B2 (en) 1999-08-26
EP0871606B1 (en) 2000-06-14
ATE193883T1 (de) 2000-06-15
HUP9802986A3 (en) 1999-12-28
JPH11514636A (ja) 1999-12-14
KR19990067247A (ko) 1999-08-16
KR100546038B1 (ko) 2006-10-04
DE69608916T2 (de) 2001-01-11
ES2148808T3 (es) 2000-10-16
ITMI952263A0 (https=) 1995-10-31

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Effective date: 20091030