RU2016116533A3 - - Google Patents
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- RU2016116533A3 RU2016116533A3 RU2016116533A RU2016116533A RU2016116533A3 RU 2016116533 A3 RU2016116533 A3 RU 2016116533A3 RU 2016116533 A RU2016116533 A RU 2016116533A RU 2016116533 A RU2016116533 A RU 2016116533A RU 2016116533 A3 RU2016116533 A3 RU 2016116533A3
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- C07C317/42—Y being a hetero atom
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
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- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
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AR082887A1 (es) | 2013-01-16 |
CA2809391A1 (en) | 2012-03-08 |
US20130273034A1 (en) | 2013-10-17 |
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AU2011295724B2 (en) | 2016-05-12 |
AU2011295724A1 (en) | 2013-05-02 |
CN103270023B (zh) | 2016-11-02 |
RU2016116533A (ru) | 2018-11-30 |
WO2012031196A1 (en) | 2012-03-08 |
RU2013114844A (ru) | 2014-10-10 |
CN106986856A (zh) | 2017-07-28 |
CN103270023A (zh) | 2013-08-28 |
US20180291000A1 (en) | 2018-10-11 |
JP2013536868A (ja) | 2013-09-26 |
US10329275B2 (en) | 2019-06-25 |
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JP6038792B2 (ja) | 2016-12-07 |
AU2011295724A8 (en) | 2013-06-20 |
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EP2611777A1 (en) | 2013-07-10 |